Artikel ; Online: Case Report: Visceral Leishmaniasis and Hemophagocytic Lymphohistiocytosis: Three Clinical Cases, Three Different Patterns.
The American journal of tropical medicine and hygiene
2021 Band 105, Heft 1, Seite(n) 138–141
Abstract: Visceral leishmaniasis (VL) is a neglected tropical disease with more than 30,000 cases annually reported worldwide. In Brazil, about 3,700 cases are annually reported. The VL clinical presentation is variable, from asymptomatic to severe cases with a ... ...
Abstract | Visceral leishmaniasis (VL) is a neglected tropical disease with more than 30,000 cases annually reported worldwide. In Brazil, about 3,700 cases are annually reported. The VL clinical presentation is variable, from asymptomatic to severe cases with a high risk of death. We reported three cases of VL with clinical sign similarities but distinct development. All cases had bone marrow hemophagocytosis and hemophagocytic lymphohistiocytosis (HLH) criteria. HLH is a rare condition that may have secondary causes, including infectious and parasitic diseases, like VL. The delayed recognition of the secondary HLH (sHLH) association to VL may cause unfavorable outcomes and death. |
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Mesh-Begriff(e) | Adult ; Amphotericin B/therapeutic use ; Antiprotozoal Agents/therapeutic use ; Brazil/epidemiology ; Fatal Outcome ; Female ; Humans ; Immunoglobulins/therapeutic use ; Leishmaniasis, Visceral/complications ; Leishmaniasis, Visceral/diagnosis ; Leishmaniasis, Visceral/drug therapy ; Leishmaniasis, Visceral/epidemiology ; Lymphohistiocytosis, Hemophagocytic/diagnosis ; Lymphohistiocytosis, Hemophagocytic/epidemiology ; Lymphohistiocytosis, Hemophagocytic/etiology ; Lymphohistiocytosis, Hemophagocytic/therapy ; Male ; Methylprednisolone/therapeutic use ; Neglected Diseases/complications ; Neglected Diseases/diagnosis ; Neglected Diseases/drug therapy ; Neglected Diseases/epidemiology ; Treatment Outcome ; Young Adult |
Chemische Substanzen | Antiprotozoal Agents ; Immunoglobulins ; Amphotericin B (7XU7A7DROE) ; Methylprednisolone (X4W7ZR7023) |
Sprache | Englisch |
Erscheinungsdatum | 2021-05-24 |
Erscheinungsland | United States |
Dokumenttyp | Case Reports |
ZDB-ID | 2942-7 |
ISSN | 1476-1645 ; 0002-9637 |
ISSN (online) | 1476-1645 |
ISSN | 0002-9637 |
DOI | 10.4269/ajtmh.20-1435 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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