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Mesh-Begriff(e)	Humans ; Immunity, Cellular ; Leishmaniasis, Cutaneous/immunology ; Leishmaniasis, Cutaneous/pathology ; Skin/pathology ; Th1 Cells/immunology ; Th2 Cells/immunology ; Transcriptome
Sprache	Englisch
Erscheinungsdatum	2021-04-03
Erscheinungsland	United States
Dokumenttyp	Letter ; Research Support, Non-U.S. Gov't
ZDB-ID	80136-7
ISSN	1523-1747 ; 0022-202X
ISSN (online)	1523-1747
ISSN	0022-202X
DOI	10.1016/j.jid.2021.03.017
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

Mesh-Begriff(e)

Humans ; Immunity, Cellular ; Leishmaniasis, Cutaneous/immunology ; Leishmaniasis, Cutaneous/pathology ; Skin/pathology ; Th1 Cells/immunology ; Th2 Cells/immunology ; Transcriptome

Sprache

Englisch

Erscheinungsdatum

2021-04-03

Erscheinungsland

United States

Dokumenttyp

Letter ; Research Support, Non-U.S. Gov't

ZDB-ID

80136-7

ISSN

1523-1747 ; 0022-202X

ISSN (online)

1523-1747

ISSN

0022-202X

DOI

10.1016/j.jid.2021.03.017

Datenquelle

MEDical Literature Analysis and Retrieval System OnLINE

Artikel: Integrated Analysis Reveals That miR-193b, miR-671, and TREM-1 Correlate With a Good Response to Treatment of Human Localized Cutaneous Leishmaniasis Caused by

Nunes, Sara / Silva, Icaro Bonyek / Ampuero, Mariana Rosa / de Noronha, Almério Libório Lopes / de Souza, Lígia Correia Lima / Correia, Thaizza Cavalcante / Khouri, Ricardo / Boaventura, Viviane Sampaio / Barral, Aldina / Ramos, Pablo Ivan Pereira / Brodskyn, Cláudia / Oliveira, Pablo Rafael Silveira / Tavares, Natalia Machado

Frontiers in immunology

2018 Band 9, Seite(n) 640

Abstract: Localized cutaneous leishmaniasis (LCL) is a chronic disease characterized by ulcerated skin lesion(s) and uncontrolled inflammation. The mechanisms underlying the pathogenesis of LCL are not completely understood, and little is known about ... ...

Abstract	Localized cutaneous leishmaniasis (LCL) is a chronic disease characterized by ulcerated skin lesion(s) and uncontrolled inflammation. The mechanisms underlying the pathogenesis of LCL are not completely understood, and little is known about posttranscriptional regulation during LCL. MicroRNAs (miRNAs) are non-coding small RNAs that regulate gene expression and can be implicated in the pathogenesis of LCL. We investigated the involvement of miRNAs and their targets genes in human LCL using publicly available transcriptome data sets followed by
Mesh-Begriff(e)	Biomarkers, Pharmacological ; CD40 Antigens/genetics ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Regulatory Networks ; Humans ; Leishmania braziliensis/physiology ; Leishmaniasis, Cutaneous/drug therapy ; Leishmaniasis, Cutaneous/genetics ; MicroRNAs/genetics ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Skin Physiological Phenomena/genetics ; Treatment Outcome ; Triggering Receptor Expressed on Myeloid Cells-1/genetics ; Wound Healing/genetics
Chemische Substanzen	Biomarkers, Pharmacological ; CD40 Antigens ; MIRN193 microRNA, human ; MIRN671 microRNA, human ; MicroRNAs ; Receptors, Tumor Necrosis Factor, Type I ; Triggering Receptor Expressed on Myeloid Cells-1
Sprache	Englisch
Erscheinungsdatum	2018-04-04
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2018.00640
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Selective Suppression of Cellular Immunity and Increased Cytotoxicity in Skin Lesions of Disseminated Leishmaniasis Uncovered by Transcriptome-Wide Analysis.

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Artikel: Integrated Analysis Reveals That miR-193b, miR-671, and TREM-1 Correlate With a Good Response to Treatment of Human Localized Cutaneous Leishmaniasis Caused by

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