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  1. Article ; Online: The effect of emergency department procedural sedation on cardiac output: post hoc analysis of a prospective study.

    Muller, Willemien D / van Ieperen, Ellen / Coffeng, Sophie M / Stolmeijer, Renate / Ter Avest, Ewoud

    European journal of emergency medicine : official journal of the European Society for Emergency Medicine

    2022  Volume 29, Issue 4, Page(s) 309–311

    MeSH term(s) Anesthesia ; Conscious Sedation ; Emergency Service, Hospital ; Humans ; Hypnotics and Sedatives/therapeutic use ; Propofol ; Prospective Studies
    Chemical Substances Hypnotics and Sedatives ; Propofol (YI7VU623SF)
    Language English
    Publishing date 2022-06-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1233544-7
    ISSN 1473-5695 ; 0969-9546
    ISSN (online) 1473-5695
    ISSN 0969-9546
    DOI 10.1097/MEJ.0000000000000922
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Sexual function in patients with metastatic midgut carcinoid tumours.

    van der Horst-Schrivers, Anouk N A / van Ieperen, Ellen / Wymenga, A N Machteld / Boezen, H Marike / Weijmar-Schultz, Willibrord C M / Kema, Ido P / Meijer, Wim G / de Herder, Wouter W / Willemse, Pax H B / Links, Thera P / de Vries, Elisabeth G E

    Neuroendocrinology

    2009  Volume 89, Issue 2, Page(s) 231–236

    Abstract: Background: Sexual dysfunction is a poorly studied aspect of quality of life in patients with midgut carcinoid tumours. We investigated whether carcinoid patients experience sexual problems.: Methods: Patients with metastatic midgut carcinoid tumours ...

    Abstract Background: Sexual dysfunction is a poorly studied aspect of quality of life in patients with midgut carcinoid tumours. We investigated whether carcinoid patients experience sexual problems.
    Methods: Patients with metastatic midgut carcinoid tumours filled in a validated questionnaire for sexual dysfunction. The prevalence of dysfunction on the subscales arousal, erection, lubrication, orgasm and dyspareunia was compared to a Dutch reference population. Plasma concentration of gonadal hormones, tryptophan and urinary 5-hydroxyindolacetic acid concentrations were measured.
    Results: 43 patients were studied, 27 men and 16 women. Sexual dysfunction was present in 29.6% of men and 6.3% of women. The prevalence of sexual dysfunction on the different subscales did not differ from the reference population. Patients with a sexual dysfunction had, compared to those without a sexual dysfunction, a longer duration of disease, 95.3 months (range 5.4-314.5) versus 18.6 months (range 0.6-167.9) (p = 0.024), lower plasma tryptophan concentration (+/-SD) of 31.5 +/- 16.1 and 48.9 +/- 14.5 micromol/l (p = 0.031), and more often used interferon-alpha, 50% of patients versus 10.5% of patients (p = 0.044).
    Conclusion: Patients with metastatic midgut carcinoid tumours do not experience sexual problems more often than a reference population. Male patients with sexual dysfunction are characterised by more long-standing disease and lower tryptophan concentration.
    MeSH term(s) Carcinoid Tumor/complications ; Carcinoid Tumor/pathology ; Female ; Humans ; Intestinal Neoplasms ; Male ; Middle Aged ; Neoplasm Metastasis ; Sex Characteristics ; Sexual Dysfunction, Physiological/complications
    Language English
    Publishing date 2009
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 123303-8
    ISSN 1423-0194 ; 0028-3835
    ISSN (online) 1423-0194
    ISSN 0028-3835
    DOI 10.1159/000178754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Sexual Function in Patients with Metastatic Midgut Carcinoid Tumours

    van der Horst-Schrivers, Anouk N.A. / van Ieperen, Ellen / Wymenga, A.N. Machteld / Boezen, H. Marike / Weijmar-Schultz, Willibrord C.M. / Kema, Ido P. / Meijer, Wim G. / de Herder, Wouter W. / Willemse, Pax H.B. / Links, Thera P. / de Vries, Elisabeth G.E.

    Neuroendocrinology

    2008  Volume 89, Issue 2, Page(s) 231–236

    Abstract: Background: Sexual dysfunction is a poorly studied aspect of quality of life in patients with midgut carcinoid tumours. We investigated whether carcinoid patients experience sexual problems. Methods: Patients with metastatic midgut carcinoid tumours ... ...

    Institution Departments of Medical Oncology Endocrinology Epidemiology Gynaecology and Pathology and Laboratory Medicine, University Medical Centre Groningen, Groningen Department of Internal Medicine, Medical Spectrum Twente, Enschede Department of Internal Medicine, West Friesch Gasthuis, Hoorn, and Department of Endocrinology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Abstract Background: Sexual dysfunction is a poorly studied aspect of quality of life in patients with midgut carcinoid tumours. We investigated whether carcinoid patients experience sexual problems. Methods: Patients with metastatic midgut carcinoid tumours filled in a validated questionnaire for sexual dysfunction. The prevalence of dysfunction on the subscales arousal, erection, lubrication, orgasm and dyspareunia was compared to a Dutch reference population. Plasma concentration of gonadal hormones, tryptophan and urinary 5-hydroxyindolacetic acid concentrations were measured. Results: 43 patients were studied, 27 men and 16 women. Sexual dysfunction was present in 29.6% of men and 6.3% of women. The prevalence of sexual dysfunction on the different subscales did not differ from the reference population. Patients with a sexual dysfunction had, compared to those without a sexual dysfunction, a longer duration of disease, 95.3 months (range 5.4–314.5) versus 18.6 months (range 0.6–167.9) (p = 0.024), lower plasma tryptophan concentration (±SD) of 31.5 ± 16.1 and 48.9 ± 14.5 μmol/l (p = 0.031), and more often used interferon-α, 50% of patients versus 10.5% of patients (p = 0.044). Conclusion: Patients with metastatic midgut carcinoid tumours do not experience sexual problems more often than a reference population. Male patients with sexual dysfunction are characterised by more long-standing disease and lower tryptophan concentration.
    Keywords Sexual behaviour ; Carcinoid tumour ; Serotonin ; Quality of life
    Language English
    Publishing date 2008-11-26
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Neuroendocrine Tumors
    ZDB-ID 123303-8
    ISSN 1423-0194 ; 0028-3835
    ISSN (online) 1423-0194
    ISSN 0028-3835
    DOI 10.1159/000178754
    Database Karger publisher's database

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