Article ; Online: Assessment of the impact of insulin resistance on pancreatic exocrine functions in obese patients
Medicine Science, Vol 10, Iss 3, Pp 998-
2021 Volume 1001
Abstract: We aimed to show whether insufficiency develops in pancreatic exocrine functions since the insulin resistance period or not. We measured the anthropometric parameters, blood glucose profile parameters and fecal elastase-1 (FE-1) levels of a total of 65 ... ...
Abstract | We aimed to show whether insufficiency develops in pancreatic exocrine functions since the insulin resistance period or not. We measured the anthropometric parameters, blood glucose profile parameters and fecal elastase-1 (FE-1) levels of a total of 65 obese patients with 35 insulin resistance and 30 without insulin resistance. Body mass indexes (BMI) and homeostasis of model assessment insulin resistance indexes (HOMA-IR) were calculated. Exocrine pancreatic insufficiency (EPI) was diagnosed with a FE-1of less than 200 mg/g (ELISA). A statistically significant difference was not observed between the mean FE-1 levels between the groups (p> 0.05). No statistically significant difference was observed between the distribution of mild and severe low FE-1 levels of the insulin resistant (IR) and Non-IR groups (p> 0.05). Our study revealed that the presence of insulin resistance does not cause any change in FE-1 levels in obese patients. [Med-Science 2021; 10(3.000): 998-1001] |
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Keywords | pancreatic exocrine function ; insulin resistance ; fecal elastase-1 ; Medicine ; R ; Medicine (General) ; R5-920 |
Subject code | 610 |
Language | English |
Publishing date | 2021-09-01T00:00:00Z |
Publisher | Society of TURAZ AKADEMI |
Document type | Article ; Online |
Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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