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Artikel ; Online: Structural basis for human Ca

Huang, Jian / Fan, Xiao / Jin, Xueqin / Lyu, Chen / Guo, Qinmeng / Liu, Tao / Chen, Jiaofeng / Davakan, Amaël / Lory, Philippe / Yan, Nieng

Cell research

2024

Abstract: ... The ... ...

Abstract	The Ca
Sprache	Englisch
Erscheinungsdatum	2024-04-11
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	1319303-x
ISSN	1748-7838 ; 1001-0602
ISSN (online)	1748-7838
ISSN	1001-0602
DOI	10.1038/s41422-024-00959-8
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Inflection Point Age in the Middle and Older Women - Jiangxi Province, China, 2020-2022.

Yang, Shanlan / Zhang, Langlang / Huang, Helang / Wang, Jiaofeng / Wu, Lei / Bao, Zhijun

China CDC weekly

2024 Band 6, Heft 9, Seite(n) 162–167

Abstract: What is already known about this topic?: Previous studies have predominantly examined the micro-level aspects of women aging inflection points, while macro-level research using big data on the inflection points of aging among middle-aged and elderly ... ...

Abstract	What is already known about this topic?: Previous studies have predominantly examined the micro-level aspects of women aging inflection points, while macro-level research using big data on the inflection points of aging among middle-aged and elderly women in China is currently limited. What is added by this report?: This study determined the inflection ages for physiological, psychological, social, and total dimensions in middle-aged, young elderly, and elderly women [(48.0-53.2) What are the implications for public health practice?: This study is important for gaining a deeper understanding of aging, identifying patterns of aging, and implementing targeted interventions to promote the overall health of Chinese women.
Sprache	Englisch
Erscheinungsdatum	2024-02-29
Erscheinungsland	China
Dokumenttyp	Journal Article
ISSN	2096-7071
ISSN (online)	2096-7071
DOI	10.46234/ccdcw2024.033
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Serum uric acid levels and prognosis of patients with non-alcoholic fatty liver disease.

Yang, Xinyi / Lin, Yan / Huang, Jiaofeng / Chi, Yujing / Wu, Yinlian / Lin, Su

Scientific reports

2024 Band 14, Heft 1, Seite(n) 5923

Abstract: Uric acid (UA) is associated with non-alcoholic fatty liver disease (NAFLD). However, it is unclear whether UA plays a predictive role in NAFLD prognosis. This study aimed to explore the relationship between UA levels and mortality in NAFLD patients ... ...

Abstract	Uric acid (UA) is associated with non-alcoholic fatty liver disease (NAFLD). However, it is unclear whether UA plays a predictive role in NAFLD prognosis. This study aimed to explore the relationship between UA levels and mortality in NAFLD patients without severe renal disease. Data were obtained from the Third National Health and Nutrition Examination Survey (NHANES). Time-dependent Cox regression was used to estimate the hazard ratio (HR) and 95% confidence interval (CI) for mortality. Overall, 2493 individuals with NAFLD and estimated glomerular filtration rate (eGFR) > 60 mL/min/1.73 m
Mesh-Begriff(e)	Humans ; Non-alcoholic Fatty Liver Disease/complications ; Uric Acid ; Nutrition Surveys ; Prognosis ; Risk Factors
Chemische Substanzen	Uric Acid (268B43MJ25)
Sprache	Englisch
Erscheinungsdatum	2024-03-11
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-55845-5
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The prognostic role of diet quality in patients with MAFLD and physical activity: data from NHANES.

Huang, Jiaofeng / Wu, Yinlian / Zheng, Jiaping / Wang, Mingfang / Goh, George Boon-Bee / Lin, Su

Nutrition & diabetes

2024 Band 14, Heft 1, Seite(n) 4

Abstract: Background and objectives: Dietary control and increased physical activity (PA) are recommended for patients with metabolic (dysfunction-) associated fatty liver disease (MAFLD). However, not all patients can sustain both exercise and a healthy diet. ... ...

Abstract	Background and objectives: Dietary control and increased physical activity (PA) are recommended for patients with metabolic (dysfunction-) associated fatty liver disease (MAFLD). However, not all patients can sustain both exercise and a healthy diet. This study explored the interaction between dietary quality, PA levels, and mortality in MAFLD patients. Methods: The Third National Health and Nutrition Examination Survey and linked mortality data were used in this study. Diet quality was assessed with the Healthy Eating Index (HEI). PA level was calculated by multiply self-reported exercise frequency and its Metabolic Equivalent A high-quality diet was associated. A Cox proportional hazard model was used to explore risk factors for mortality in MAFLD patients. Results: In total, 3709 participants with MAFLD were included in the final analysis. The median follow-up time was 26.2 (interquartile range 19.3-28.1) years and 1549 (41.8%) deaths were recorded over follow-up. Cox multivariate regression was used to adjust for potential confounders of mortality. The results showed both HEI score and PA level were inversely correlated with all-cause mortality (P < 0.05). In the subgroup analysis stratified by PA level, higher diet quality decreased all-cause mortality, cardiovascular-related mortality and cancer-related mortality in PA inactive of MAFLD patients (P < 0.05), but these correlations were not present in active PA groups. Conclusion: Healthy diet and physical activity may have different impact as lifestyle interventions for MAFLD. A high-quality diet is associated less mortality in inactive individuals with MAFLD but not in those with active PA levels. Sedentary individuals require healthier diet.
Mesh-Begriff(e)	Humans ; Nutrition Surveys ; Prognosis ; Diet ; Risk Factors ; Exercise ; Non-alcoholic Fatty Liver Disease
Sprache	Englisch
Erscheinungsdatum	2024-02-23
Erscheinungsland	England
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2609314-5
ISSN	2044-4052 ; 2044-4052
ISSN (online)	2044-4052
ISSN	2044-4052
DOI	10.1038/s41387-024-00261-x
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The trends of disease burden due to high temperature in Mainland China from 1990 to 2019 and its prediction to 2030

Jiaolong Zheng / Haiyan Lin / Jingyi Ling / Jiaofeng Huang / Dongliang Li

Scientific Reports, Vol 13, Iss 1, Pp 1-

2023 Band 11

Abstract: Abstract The risk of high-temperature-related diseases is increasing owing to global warming. This study aimed to assess the trend of disease burden caused by high temperatures in Mainland China from 1990 to 2019 and to predict the trend of disease ... ...

Abstract	Abstract The risk of high-temperature-related diseases is increasing owing to global warming. This study aimed to assess the trend of disease burden caused by high temperatures in Mainland China from 1990 to 2019 and to predict the trend of disease burden over the next 10 years. The latest data were downloaded from the Global Burden of Disease Database (GBD) for analysis, and the disease burden related to high temperature was described by mortality and disability-adjusted life-years (DALYs) and stratified by etiology, sex, and age. Statistical analyses were performed using the R software. In 2019, there were 13,907 deaths attributed to high temperatures in Mainland China, and this was 29.55% higher than the 10,735 deaths in 1990. Overall, the age-standardized mortality and DALYs attributed to high temperatures showed a downward trend from 1990 to 2019. We observed an etiological shift in high-temperature-related diseases. The age-standardized DALYs contribution attributed to high temperatures in 1990 was mainly from communicable, maternal, neonatal, and nutritional diseases (CMNND) (21.81/100,000), followed by injury (18.30/100,000) and non-communicable diseases (10.40/100,000). In 2019, the largest contribution shifted to non-communicable diseases (10.07/100,000), followed by injuries (5.21/100,000), and CMNND (2.30/100,000). The disease burden attributed to high temperatures was higher in males than in females and increased with age. In 2030, the mortality rate and DALYs due to high temperatures are predicted to decrease further, and the largest contribution will come from chronic non-communicable diseases, the occurrence of which will remain at a high level over the next 10 years. The burden of disease due to high temperatures in Mainland China is still heavy, mainly due to population aging and an increase in non-communicable diseases.
Schlagwörter	Medicine ; R ; Science ; Q
Thema/Rubrik (Code)	610
Sprache	Englisch
Erscheinungsdatum	2023-12-01T00:00:00Z
Verlag	Nature Portfolio
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: The trends of disease burden due to high temperature in Mainland China from 1990 to 2019 and its prediction to 2030.

Zheng, Jiaolong / Lin, Haiyan / Ling, Jingyi / Huang, Jiaofeng / Li, Dongliang

Scientific reports

2023 Band 13, Heft 1, Seite(n) 22238

Abstract: The risk of high-temperature-related diseases is increasing owing to global warming. This study aimed to assess the trend of disease burden caused by high temperatures in Mainland China from 1990 to 2019 and to predict the trend of disease burden over ... ...

Abstract	The risk of high-temperature-related diseases is increasing owing to global warming. This study aimed to assess the trend of disease burden caused by high temperatures in Mainland China from 1990 to 2019 and to predict the trend of disease burden over the next 10 years. The latest data were downloaded from the Global Burden of Disease Database (GBD) for analysis, and the disease burden related to high temperature was described by mortality and disability-adjusted life-years (DALYs) and stratified by etiology, sex, and age. Statistical analyses were performed using the R software. In 2019, there were 13,907 deaths attributed to high temperatures in Mainland China, and this was 29.55% higher than the 10,735 deaths in 1990. Overall, the age-standardized mortality and DALYs attributed to high temperatures showed a downward trend from 1990 to 2019. We observed an etiological shift in high-temperature-related diseases. The age-standardized DALYs contribution attributed to high temperatures in 1990 was mainly from communicable, maternal, neonatal, and nutritional diseases (CMNND) (21.81/100,000), followed by injury (18.30/100,000) and non-communicable diseases (10.40/100,000). In 2019, the largest contribution shifted to non-communicable diseases (10.07/100,000), followed by injuries (5.21/100,000), and CMNND (2.30/100,000). The disease burden attributed to high temperatures was higher in males than in females and increased with age. In 2030, the mortality rate and DALYs due to high temperatures are predicted to decrease further, and the largest contribution will come from chronic non-communicable diseases, the occurrence of which will remain at a high level over the next 10 years. The burden of disease due to high temperatures in Mainland China is still heavy, mainly due to population aging and an increase in non-communicable diseases.
Mesh-Begriff(e)	Infant, Newborn ; Male ; Female ; Humans ; Life Expectancy ; Quality-Adjusted Life Years ; Temperature ; Noncommunicable Diseases ; Cost of Illness ; Nutrition Disorders ; Persistent Infection ; China/epidemiology ; Risk Factors ; Global Health
Sprache	Englisch
Erscheinungsdatum	2023-12-14
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-49491-6
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Pan-cancer analysis revealing DAAM1 as a novel predictive biomarker for PD-1/PD-L1 blockade in clear cell renal cell carcinoma.

Mei, Jie / Fan, Honghong / Zhou, Jiaofeng / Huang, Dingwei / Xu, Junying / Zhu, Yichao

MedComm

2022 Band 3, Heft 4, Seite(n) e177

Sprache	Englisch
Erscheinungsdatum	2022-10-27
Erscheinungsland	China
Dokumenttyp	Journal Article
ISSN	2688-2663
ISSN (online)	2688-2663
DOI	10.1002/mco2.177
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The association between serum 25-hydroxyvitamin D and the prevalence of herpes simplex virus.

Huang, Jiaofeng / Wu, Yinlian / Wang, Mingfang / Lin, Su

Journal of medical virology

2022 Band 95, Heft 1, Seite(n) e28297

Abstract: Previous studies have reported a potential anti-infection effect for vitamin D. However, the relationship between vitamin D status and herpes simplex virus (HSV) infection has not yet been evaluated. Therefore, this study aimed to determine the ... ...

Abstract	Previous studies have reported a potential anti-infection effect for vitamin D. However, the relationship between vitamin D status and herpes simplex virus (HSV) infection has not yet been evaluated. Therefore, this study aimed to determine the association between serum 25-hydroxyvitamin D [25(OH)D] and infection with HSV types 1 and 2 (HSV-1 and HSV-2). Data were collected from the National Health and Nutrition Examination Survey from 2007 to 2016. The association between 25(OH)D and HSV prevalence was evaluated using propensity score matching (PSM) and univariate and multivariate logistic regression analyses. Overall, 14 174 participants were included in the final analysis. Before PSM, 8639 (60.9%) had positive HSV-1 and 2636 (18.6%) had HSV-2. The HSV-1 and HSV-2 positive groups had more females and older individuals (p < 0.05). The HSV-2 patients had lower 25(OH)D levels than those with HSV-1. Age and gender did not differ in the groups after PSM (p > 0.05). The 25(OH)D level was significantly lower in the HSV-1 and HSV-2 groups than in the non-HSV infection groups. Multivariate logistic regression showed that serum 25(OH)D level was negatively associated with HSV-1 and HSV-2 infection (odds ratio [OR] = 0.730 and 0.691, p < 0.001, respectively). Vitamin D deficiency was an independent risk factor for both HSV-1 and HSV-2 (adjusted OR = 2.205 and 2.704, p < 0.001, respectively). Lower serum 25(OH)D levels correlated significantly with increased HSV-1 and HSV-2 infection risk.
Mesh-Begriff(e)	Female ; Humans ; Nutrition Surveys ; Prevalence ; Vitamin D ; Herpes Simplex/epidemiology ; Herpesvirus 1, Human ; Herpesvirus 2, Human ; Risk Factors
Chemische Substanzen	25-hydroxyvitamin D (A288AR3C9H) ; Vitamin D (1406-16-2)
Sprache	Englisch
Erscheinungsdatum	2022-11-18
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	752392-0
ISSN	1096-9071 ; 0146-6615
ISSN (online)	1096-9071
ISSN	0146-6615
DOI	10.1002/jmv.28297
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Evaluating the global, regional, and national impact of syphilis

Tao Chen / Bo Wan / Mingfang Wang / Su Lin / Yinlian Wu / Jiaofeng Huang

Scientific Reports, Vol 13, Iss 1, Pp 1-

results from the global burden of disease study 2019

2023 Band 11

Abstract: Abstract Syphilis is a global public health concern. This study aimed to assess the global and regional burden of syphilis from 1990 to 2019. Disease burden was evaluated using disability-adjusted life-years (DALYs) and prevalence. Data were extracted ... ...

Abstract	Abstract Syphilis is a global public health concern. This study aimed to assess the global and regional burden of syphilis from 1990 to 2019. Disease burden was evaluated using disability-adjusted life-years (DALYs) and prevalence. Data were extracted from the 2019 global burden of disease Study, an open database available for download. Age-standardized rates (ASR) and estimated annual percentage changes (EAPC) were calculated to evaluate the syphilis burden over time. In 2019, the total number of prevalent cases of syphilis was 49.71 million worldwide. The ASR of prevalence was stable from 1990 to 2019 with an EAPC of 0.00 (95% CI − 0.10–0.11). The number of DALYs caused by syphilis was 7.36 million in 2019, reflecting a reduction of 16.38% compared with that in 1990 (8.80 million). The ASR of DALYs exhibited a decreasing trend from 1990 to 2019 (EAPC = − 1.01; 95% CI − 1.19 to − 0.84), with the highest rates observed in the younger age group (< 14 years old). In 2019, the highest ASR of DALYs was found in low sociodemographic index (SDI) regions (239.21/100,000), and the lowest in high SDI regions (3.14/100,000). Generally, the ASR of DALYs decreased as the SDI increased. The top three countries with the highest ASR of DALYs for syphilis were the Solomon Islands, Equatorial Guinea, and Liberia. While the global prevalence of syphilis remained persistently high from 1990 to 2019, there has been a recent decrease in the ASR of DALYs. Increased attention should be dedicated to younger populations and regions characterized by low SDIs.
Schlagwörter	Medicine ; R ; Science ; Q
Thema/Rubrik (Code)	306
Sprache	Englisch
Erscheinungsdatum	2023-07-01T00:00:00Z
Verlag	Nature Portfolio
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: Pan‐cancer analysis revealing DAAM1 as a novel predictive biomarker for PD‐1/PD‐L1 blockade in clear cell renal cell carcinoma

Jie Mei / Honghong Fan / Jiaofeng Zhou / Dingwei Huang / Junying Xu / Yichao Zhu

MedComm, Vol 3, Iss 4, Pp n/a-n/a (2022)

2022

Schlagwörter	Medicine ; R
Sprache	Englisch
Erscheinungsdatum	2022-12-01T00:00:00Z
Verlag	Wiley
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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