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  1. Artikel: Correction to: CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases.

    Vangah, Somayeh Jolany / Katalani, Camellia / Boone, Hannah A / Hajizade, Abbas / Sijercic, Adna / Ahmadian, Gholamreza

    Biological procedures online

    2020  Band 22, Heft 1, Seite(n) 24

    Abstract: An amendment to this paper has been published and can be accessed via the original article. ...

    Abstract An amendment to this paper has been published and can be accessed via the original article.
    Sprache Englisch
    Erscheinungsdatum 2020-11-07
    Erscheinungsland England
    Dokumenttyp Published Erratum
    ZDB-ID 2027823-8
    ISSN 1480-9222
    ISSN 1480-9222
    DOI 10.1186/s12575-020-00136-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases.

    Jolany Vangah, Somayeh / Katalani, Camellia / Booneh, Hannah A / Hajizade, Abbas / Sijercic, Adna / Ahmadian, Gholamreza

    Biological procedures online

    2020  Band 22, Seite(n) 22

    Abstract: Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to CRISPR's ... ...

    Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to CRISPR's remarkable gene editing and cleaving abilities. While the application of CRISPR in human genome editing and diagnosis needs to be researched more fully, and any potential side effects or ambiguities resolved, CRISPR has already shown its capacity in an astonishing variety of applications related to genome editing and genetic engineering. One of its most currently relevant applications is in diagnosis of infectious and non-infectious diseases. Since its initial discovery, 6 types and 22 subtypes of CRISPR systems have been discovered and explored. Diagnostic CRISPR systems are most often derived from types II, V, and VI. Different types of CRISPR-Cas systems which have been identified in different microorganisms can target DNA (e.g. Cas9 and Cas12 enzymes) or RNA (e.g. Cas13 enzyme). Viral, bacterial, and non-infectious diseases such as cancer can all be diagnosed using the cleavage activity of CRISPR enzymes from the aforementioned types. Diagnostic tests using Cas12 and Cas13 enzymes have already been developed for detection of the emerging SARS-CoV-2 virus. Additionally, CRISPR diagnostic tests can be performed using simple reagents and paper-based lateral flow assays, which can potentially reduce laboratory and patient costs significantly. In this review, the classification of CRISPR-Cas systems as well as the basis of the CRISPR/Cas mechanisms of action will be presented. The application of these systems in medical diagnostics with emphasis on the diagnosis of COVID-19 will be discussed.
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-09-14
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2027823-8
    ISSN 1480-9222
    ISSN 1480-9222
    DOI 10.1186/s12575-020-00135-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Correction to

    Somayeh Jolany vangah / Camellia Katalani / Hannah A. Boone / Abbas Hajizade / Adna Sijercic / Gholamreza Ahmadian

    Biological Procedures Online, Vol 22, Iss 1, Pp 1-

    CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases

    2020  Band 1

    Abstract: An amendment to this paper has been published and can be accessed via the original article. ...

    Abstract An amendment to this paper has been published and can be accessed via the original article.
    Schlagwörter Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
    Sprache Englisch
    Erscheinungsdatum 2020-11-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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  4. Artikel ; Online: CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases

    Somayeh Jolany vangah / Camellia Katalani / Hannah A. Booneh / Abbas Hajizade / Adna Sijercic / Gholamreza Ahmadian

    Biological Procedures Online, Vol 22, Iss 1, Pp 1-

    2020  Band 14

    Abstract: Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to ... ...

    Abstract Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to CRISPR’s remarkable gene editing and cleaving abilities. While the application of CRISPR in human genome editing and diagnosis needs to be researched more fully, and any potential side effects or ambiguities resolved, CRISPR has already shown its capacity in an astonishing variety of applications related to genome editing and genetic engineering. One of its most currently relevant applications is in diagnosis of infectious and non-infectious diseases. Since its initial discovery, 6 types and 22 subtypes of CRISPR systems have been discovered and explored. Diagnostic CRISPR systems are most often derived from types II, V, and VI. Different types of CRISPR-Cas systems which have been identified in different microorganisms can target DNA (e.g. Cas9 and Cas12 enzymes) or RNA (e.g. Cas13 enzyme). Viral, bacterial, and non-infectious diseases such as cancer can all be diagnosed using the cleavage activity of CRISPR enzymes from the aforementioned types. Diagnostic tests using Cas12 and Cas13 enzymes have already been developed for detection of the emerging SARS-CoV-2 virus. Additionally, CRISPR diagnostic tests can be performed using simple reagents and paper-based lateral flow assays, which can potentially reduce laboratory and patient costs significantly. In this review, the classification of CRISPR-Cas systems as well as the basis of the CRISPR/Cas mechanisms of action will be presented. The application of these systems in medical diagnostics with emphasis on the diagnosis of COVID-19 will be discussed.
    Schlagwörter CRISPR-Cas ; COVID-19 ; Diagnostic test ; SHERLOCK ; DETECTR ; Single guide RNA (sgRNA) ; Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2020-09-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  5. Artikel ; Online: CRISPR-Based Diagnosis of Infectious and Noninfectious Diseases

    Jolany vangah, Somayeh / Katalani, Camellia / Booneh, Hannah A. / Hajizade, Abbas / Sijercic, Adna / Ahmadian, Gholamreza

    Biological Procedures Online

    2020  Band 22, Heft 1

    Abstract: Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to ... ...

    Abstract Abstract Interest in CRISPR technology, an instrumental component of prokaryotic adaptive immunity which enables prokaryotes to detect any foreign DNA and then destroy it, has gained popularity among members of the scientific community. This is due to CRISPR’s remarkable gene editing and cleaving abilities. While the application of CRISPR in human genome editing and diagnosis needs to be researched more fully, and any potential side effects or ambiguities resolved, CRISPR has already shown its capacity in an astonishing variety of applications related to genome editing and genetic engineering. One of its most currently relevant applications is in diagnosis of infectious and non-infectious diseases. Since its initial discovery, 6 types and 22 subtypes of CRISPR systems have been discovered and explored. Diagnostic CRISPR systems are most often derived from types II, V, and VI. Different types of CRISPR-Cas systems which have been identified in different microorganisms can target DNA (e.g. Cas9 and Cas12 enzymes) or RNA (e.g. Cas13 enzyme). Viral, bacterial, and non-infectious diseases such as cancer can all be diagnosed using the cleavage activity of CRISPR enzymes from the aforementioned types. Diagnostic tests using Cas12 and Cas13 enzymes have already been developed for detection of the emerging SARS-CoV-2 virus. Additionally, CRISPR diagnostic tests can be performed using simple reagents and paper-based lateral flow assays, which can potentially reduce laboratory and patient costs significantly. In this review, the classification of CRISPR-Cas systems as well as the basis of the CRISPR/Cas mechanisms of action will be presented. The application of these systems in medical diagnostics with emphasis on the diagnosis of COVID-19 will be discussed.
    Schlagwörter General Biochemistry, Genetics and Molecular Biology ; covid19
    Sprache Englisch
    Verlag Springer Science and Business Media LLC
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 2027823-8
    ISSN 1480-9222
    ISSN 1480-9222
    DOI 10.1186/s12575-020-00135-3
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

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