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  1. AU=Khosravi-Far Roya
  2. AU="Udeochu, Joe C"
  3. AU="Osoba, Osonde A." AU="Osoba, Osonde A."
  4. AU="Palani, Sowmiya"
  5. AU="Manfred Frick"
  6. AU="Jensen, Leonard"
  7. AU="Pakhomov, Evgeny A."
  8. AU="Subramanyam, Chithirala Bala"
  9. AU=Petrek J A
  10. AU="Thomson-Baker, B"
  11. AU=Shahidi Shahrzad
  12. AU="Taylor, Holly A"
  13. AU="Yeong Jeong Jeon"
  14. AU="Bueno-Cavanillas, Aurora"
  15. AU="Kavčič, Tina"
  16. AU="Arias-Jiménez, José Luís"
  17. AU="Tünçok, Ekin"
  18. AU="Roberto Toro"
  19. AU="Bharti Sahu"
  20. AU="Soo-Yeon Choi"
  21. AU="Nono, Sandra"
  22. AU="Diepens, Robin J W"
  23. AU="Baselga-Garriga, Clara"

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  1. Buch: Programmed cell death in cancer progression and therapy

    Khosravi-Far, Roya / White, Eileen

    (Advances in experimental medicine and biology ; 615)

    2008  

    Verfasserangabe Roya Khosravi-Far ; Eileen White
    Serientitel Advances in experimental medicine and biology ; 615
    Überordnung
    Sprache Englisch
    Verlag Springer
    Erscheinungsort New York u.a.
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT015418803
    ISBN 978-1-4020-6553-8 ; 9781402065545 ; 1-4020-6553-1 ; 140206554X
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Artikel: Graph Convolutional Network for predicting secondary structure of RNA.

    Busaranuvong, Palawat / Ammartayakun, Aukkawut / Korkin, Dmitry / Khosravi-Far, Roya

    Research square

    2024  

    Abstract: The prediction of RNA secondary structures is essential for understanding its underlying principles and applications in diverse fields, including molecular diagnostics and RNA-based therapeutic strategies. However, the complexity of the search space ... ...

    Abstract The prediction of RNA secondary structures is essential for understanding its underlying principles and applications in diverse fields, including molecular diagnostics and RNA-based therapeutic strategies. However, the complexity of the search space presents a challenge. This work proposes a Graph Convolutional Network (GCNfold) for predicting the RNA secondary structure. GCNfold considers an RNA sequence as graph-structured data and predicts posterior base-pairing probabilities given the prior base-pairing probabilities, calculated using McCaskill's partition function. The performance of GCNfold surpasses that of the state-of-the-art folding algorithms, as we have incorporated minimum free energy information into the richly parameterized network, enhancing its robustness in predicting non-homologous RNA secondary structures. A Symmetric Argmax Post-processing algorithm ensures that GCNfold formulates valid structures. To validate our algorithm, we applied it to the SARS-CoV-2 E gene and determined the secondary structure of the E-gene across the
    Sprache Englisch
    Erscheinungsdatum 2024-02-23
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.21203/rs.3.rs-3798842/v1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: VIRAL TRANSPORTATION IN COVID-19 PANDEMIC: INACTIVATED VIRUS TRANSPORTATION SHOULD BE IMPLEMENTED FOR SAFE TRANSPORTATION AND HANDLING AT DIAGNOSTICS LABORATORIES.

    Dewar, Rajan / Baunoch, David / Wojno, Kirk / Parkash, Vinita / Khosravi-Far, Roya

    Archives of pathology & laboratory medicine

    2020  

    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-04-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 194119-7
    ISSN 1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
    ISSN (online) 1543-2165
    ISSN 0363-0153 ; 0096-8528 ; 0003-9985
    DOI 10.5858/arpa.2020-0175-LE
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Viral Transportation in Covid-19 Pandemic: Inactivated Virus Transportation Should Be Implemented for Safe Transportation and Handling at Diagnostics Laboratories

    Dewar, Rajan / Baunoch, David / Wojno, Kirk / Parkash, Vinita / Khosravi-Far, Roya

    Arch. pathol. lab. med. (1976)

    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #32298137
    Datenquelle COVID19

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  5. Artikel ; Online: Ser81 Survivin Induced Protein Kinase A (PKA)-dependent Phosphatidylinositol 3-kinase (PI3K) Activity

    Ferry Sandra / Roya Khosravi-Far

    Indonesian Biomedical Journal, Vol 6, Iss 3, Pp 157-

    2014  Band 62

    Abstract: BACKGROUND: Our previous report showed that phosphorylated-survivin at Ser81 induces survivin back loop to activate protein kinase A (PKA) in the cytoprotection mechanism. Activated PKA could possibly induce the cytoprotection via Phosphatydilinositol 3- ... ...

    Abstract BACKGROUND: Our previous report showed that phosphorylated-survivin at Ser81 induces survivin back loop to activate protein kinase A (PKA) in the cytoprotection mechanism. Activated PKA could possibly induce the cytoprotection via Phosphatydilinositol 3-kinase (PI3K). Therefore our current study was conducted to investigate the possibility of survivin-PKA-PI3K signaling pathway. METHODS: Viral productions by BOSC23 cells of Survivin, Antisense Survivin (Survivin-AS) and Ser81Ala mutant (Survivin-S81A) in pMSCV-IRES-GFP vector with cytomegalovirus (CMV) promoter were conducted. L929 cells were pretreated with/without PKI 6-22 amide and infected with viral particle of Survivin, Survivin-AS, Survivin-S81A or vector only. Cells were harvested, lysed and immunoprecipitated with anti-PI3K (p85) antibody and immunoblotted to detect PI3K (p85) and phospho-(Tyr) p85 PI3K. To confirm PI3K activation, PI3K Activity Assay was conducted by using phosphoinositide fraction containing PtdIns(4,5)P2 and [32P]ATP. RESULTS: Immunoblot and PI3K activity results showed similar results. Upon infection of virus with survivin, a markedly increased level of tyrosine phosphorylation of p85 PI3K or PI3K activity in L929 cells was seen. Low levels of tyrosine phosphorylation of p85 PI3K or PI3K activity were observed for Survivin-AS and Survivin-S81A-viral-infected L929 cells. With higher concentrations of Survivin-viral-infection, levels of tyrosine phosphorylation of p85 PI3K or PI3K activity in L929 cells were gradually increased. However, when L929 cells were pretreated with PKI 6-22 amide, prior to Survivin-viral-infection, level of tyrosine phosphorylation level of p85 PI3K or PI3K activity was detected much lower. CONCLUSIONS: Our result suggest that Ser81 Survivin play role in inducing PI3K activation and the Survivin-PI3K signaling pathway was PKA-dependent. KEYWORDS: Ser81, Survivin, PKA, PI3K, L929.
    Schlagwörter Medicine (General) ; R5-920
    Sprache Englisch
    Erscheinungsdatum 2014-12-01T00:00:00Z
    Verlag Secretariat of The Indonesian Biomedical Journal
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Buch: Programmed cell death, general principles for studying cell death

    Khosravi-Far, Roya

    (Methods in enzymology ; 442)

    2008  

    Verfasserangabe ed. by Roya Khosravi-Far
    Serientitel Methods in enzymology ; 442
    Sprache Englisch
    Umfang XLVIII, 493, [15] S., Ill., graph. Darst.
    Dokumenttyp Buch
    ISBN 9780123743121 ; 0123743125
    Datenquelle Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung

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  7. Buch: Programmed cell death, general principles for studying cell death

    Khosravi-Far, Roya

    (Methods in enzymology ; ...)

    2008  

    Verfasserangabe ed. by Roya Khosravi-Far
    Serientitel Methods in enzymology
    ...
    Sprache Englisch
    Erscheinungsverlauf 2008-9999
    Verlag Elsevier, Acad. Press
    Erscheinungsort Amsterdam u.a.
    Dokumenttyp Buch
    Datenquelle Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung

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  8. Buch: Programmed cell death, the biology and therapeutic implications of cell death

    Khosravi-Far, Roya

    (Methods in enzymology ; ...)

    2008  

    Verfasserangabe ed. by Roya Khosravi-Far
    Serientitel Methods in enzymology
    ...
    Sprache Englisch
    Erscheinungsverlauf 2008-9999
    Verlag Elsevier, Acad. Press
    Erscheinungsort Amsterdam u.a.
    Dokumenttyp Buch
    Datenquelle Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung

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  9. Buch: Programmed cell death, general principles for studying cell death

    Khosravi-Far, Roya

    (Methods in enzymology ; 442)

    2008  

    Verfasserangabe ed. by Roya Khosravi-Far
    Serientitel Methods in enzymology ; 442
    Sprache Englisch
    Umfang XLVIII, 493, [15] S., Ill., graph. Darst.
    Verlag Elsevier, Acad. Press
    Erscheinungsort Amsterdam u.a.
    Dokumenttyp Buch
    ISBN 9780123743121 ; 0123743125
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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