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  1. Artikel ; Online: More rational use of benzodiazepines in the outpatient clinic.

    Kurihara, Teruyuki

    Internal medicine (Tokyo, Japan)

    2007  Band 46, Heft 6, Seite(n) 255–256

    Mesh-Begriff(e) Adult ; Age Distribution ; Aged ; Ambulatory Care/statistics & numerical data ; Anxiety/therapy ; Benzodiazepines/therapeutic use ; Drug Utilization Review ; Female ; France ; Humans ; Japan ; Male ; Middle Aged ; Practice Patterns, Physicians'/statistics & numerical data ; Sex Distribution ; Sleep Initiation and Maintenance Disorders/therapy ; Stress, Psychological/therapy
    Chemische Substanzen Benzodiazepines (12794-10-4)
    Sprache Englisch
    Erscheinungsdatum 2007-03-15
    Erscheinungsland Japan
    Dokumenttyp Editorial
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.46.0172
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Headache, neck pain, and stroke as characteristic manifestations of the cerebral artery dissection.

    Kurihara, Teruyuki

    Internal medicine (Tokyo, Japan)

    2007  Band 46, Heft 6, Seite(n) 257–258

    Mesh-Begriff(e) Adult ; Aneurysm, Dissecting/complications ; Aneurysm, Dissecting/diagnosis ; Aneurysm, Dissecting/therapy ; Cerebral Arteries/injuries ; Cerebrovascular Trauma/complications ; Female ; Headache/etiology ; Humans ; Intracranial Aneurysm/complications ; Intracranial Aneurysm/diagnosis ; Intracranial Aneurysm/therapy ; Male ; Middle Aged ; Neck Pain/etiology ; Rupture, Spontaneous/complications ; Stroke/etiology
    Sprache Englisch
    Erscheinungsdatum 2007-03-15
    Erscheinungsland Japan
    Dokumenttyp Case Reports ; Editorial ; Review
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.46.0173
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: The gut function test to clarify the mechanism of constipation in familial amyloid polyneuropathy.

    Kurihara, Teruyuki

    Internal medicine (Tokyo, Japan)

    2006  Band 45, Heft 22, Seite(n) 1265–1266

    Mesh-Begriff(e) Amyloid Neuropathies, Familial/complications ; Amyloid Neuropathies, Familial/physiopathology ; Constipation/etiology ; Humans ; Intestines/physiopathology
    Sprache Englisch
    Erscheinungsdatum 2006-12-15
    Erscheinungsland Japan
    Dokumenttyp Editorial
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.45.0171
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Mitochondrial neurogastrointestinal encephalomyopathy and its pathophysiology.

    Kurihara, Teruyuki

    Internal medicine (Tokyo, Japan)

    2006  Band 45, Heft 7, Seite(n) 415–416

    Mesh-Begriff(e) Adult ; DNA, Mitochondrial/genetics ; Female ; Gastrointestinal Diseases/complications ; Gastrointestinal Diseases/genetics ; Humans ; Mitochondrial Encephalomyopathies/complications ; Mitochondrial Encephalomyopathies/enzymology ; Mitochondrial Encephalomyopathies/genetics ; Mutation ; Ophthalmoplegia/genetics ; Thymidine Phosphorylase/genetics
    Chemische Substanzen DNA, Mitochondrial ; Thymidine Phosphorylase (EC 2.4.2.4)
    Sprache Englisch
    Erscheinungsdatum 2006-05-01
    Erscheinungsland Japan
    Dokumenttyp Comment ; Editorial
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.45.0148
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Abducens nerve palsy and ipsilateral incomplete Horner syndrome: a significant sign of locating the lesion in the posterior cavernous sinus.

    Kurihara, Teruyuki

    Internal medicine (Tokyo, Japan)

    2006  Band 45, Heft 17, Seite(n) 993–994

    Mesh-Begriff(e) Abducens Nerve/pathology ; Abducens Nerve Diseases/diagnosis ; Abducens Nerve Diseases/etiology ; Adult ; Brain Neoplasms/complications ; Brain Neoplasms/diagnosis ; Cavernous Sinus ; Female ; Horner Syndrome/diagnosis ; Horner Syndrome/etiology ; Humans ; Male ; Middle Aged ; Sympathetic Nervous System/pathology
    Sprache Englisch
    Erscheinungsdatum 2006-10-02
    Erscheinungsland Japan
    Dokumenttyp Comment ; Editorial
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.45.0163
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Seronegative myasthenia gravis and muscle atrophy of the tongue.

    Kurihara, Teruyuki

    Internal medicine (Tokyo, Japan)

    2005  Band 44, Heft 6, Seite(n) 536–537

    Mesh-Begriff(e) Humans ; Muscular Atrophy/etiology ; Muscular Atrophy/physiopathology ; Myasthenia Gravis/complications ; Myasthenia Gravis/physiopathology ; Tongue/innervation ; Tongue/physiopathology
    Sprache Englisch
    Erscheinungsdatum 2005-06-28
    Erscheinungsland Japan
    Dokumenttyp Comment ; Editorial
    ZDB-ID 32371-8
    ISSN 0918-2918 ; 0021-5120
    ISSN 0918-2918 ; 0021-5120
    DOI 10.2169/internalmedicine.44.536
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Isolated angitis of the central nervous system: early diagnosis and treatment.

    Kurihara, Teruyuki

    Internal medicine (Tokyo, Japan)

    2005  Band 44, Heft 8, Seite(n) 783–784

    Mesh-Begriff(e) Adrenal Cortex Hormones/administration & dosage ; Adrenal Cortex Hormones/therapeutic use ; Biopsy ; Disorders of Excessive Somnolence/etiology ; Humans ; Intracellular Signaling Peptides and Proteins/cerebrospinal fluid ; Memory Disorders/etiology ; Neuropeptides/cerebrospinal fluid ; Orexins ; Vasculitis, Central Nervous System/diagnosis ; Vasculitis, Central Nervous System/drug therapy
    Chemische Substanzen Adrenal Cortex Hormones ; Intracellular Signaling Peptides and Proteins ; Neuropeptides ; Orexins
    Sprache Englisch
    Erscheinungsdatum 2005-09-06
    Erscheinungsland Japan
    Dokumenttyp Comment ; Editorial
    ZDB-ID 32371-8
    ISSN 0918-2918 ; 0021-5120
    ISSN 0918-2918 ; 0021-5120
    DOI 10.2169/internalmedicine.44.783
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Aggregate Formation of BODIPY-Tethered Oligonucleotides That Led to Efficient Intracellular Penetration and Gene Regulation.

    Asahi, Wataru / Kurihara, Ryohsuke / Takeyama, Kotaro / Umehara, Yui / Kimura, Yu / Kondo, Teruyuki / Tanabe, Kazuhito

    ACS applied bio materials

    2019  Band 2, Heft 10, Seite(n) 4456–4463

    Abstract: Exogenous nucleic acids showed low efficiency regarding cellular uptake and low stability in biological conditions; therefore, a number of techniques have been developed to improve their basic properties. One of the best solutions is the application of ... ...

    Abstract Exogenous nucleic acids showed low efficiency regarding cellular uptake and low stability in biological conditions; therefore, a number of techniques have been developed to improve their basic properties. One of the best solutions is the application of nanosized particles consisting of oligonucleotides that penetrate the cell membrane without any additives and exhibit high stability in cells. In this report, we employed a simple approach to address the basic properties of nanoparticles of oligonucleotides in biological systems. We prepared BODIPY-labeled oligonucleotides that carried an exclusive modification at the strand end. BODIPY shows high hydrophobicity and fluorescent emission; therefore, the oligonucleotides formed nanosized aggregates in aqueous solution and their behaviors in cells or tissues were easily tracked. Detailed experiments revealed that aggregate formation was indispensable for the high cellular uptake of the oligonucleotides via scavenger-receptor-mediated endocytosis. In addition, the aggregates provided an efficient gene regulation in living cells and tumor tissues transplanted into mice.
    Sprache Englisch
    Erscheinungsdatum 2019-10-03
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2576-6422
    ISSN (online) 2576-6422
    DOI 10.1021/acsabm.9b00631
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: New classification and treatment for myotonic disorders.

    Kurihara, Teruyuki

    Internal medicine (Tokyo, Japan)

    2005  Band 44, Heft 10, Seite(n) 1027–1032

    Abstract: Myotonia is repetitive firing of muscle action potentials causing prolonged muscle contractions even after mechanical stimulations to the muscles have ceased. Most common myotonic disorder is myotonic dystrophy which is now termed DM1, myotonic dystrophy ...

    Abstract Myotonia is repetitive firing of muscle action potentials causing prolonged muscle contractions even after mechanical stimulations to the muscles have ceased. Most common myotonic disorder is myotonic dystrophy which is now termed DM1, myotonic dystrophy type 1. In Japan, proximal myotonic myopathy, which is now called DM2 has not been reported. Both DM1 and DM2 have Cl channel abnormality which causes myotonia. Less commonly we encounter Thomsen's disease, and autosomal recessive generalized myotonia (Becker type) which also have a Cl channel abnormality. There are other myotonic disorders related to Na channelopathy which include three disorders: paramyotonia congenita, adynamia episodica hereditaria, and myotonia fluctuans. Myotonia has been treated by various Na channel blockers, mexiletine, phenytoin, and carbamazepine, but they were originally developed for cardiac arrhythmia, or seizure disorders and they have undesirable side effects, weakness. Comprehensive treatment includes myotonia control without reducing the strength, and care for systemic manifestations of DM1.
    Mesh-Begriff(e) Humans ; Myotonic Disorders/classification ; Myotonic Disorders/therapy
    Sprache Englisch
    Erscheinungsdatum 2005-11-14
    Erscheinungsland Japan
    Dokumenttyp Journal Article ; Review
    ZDB-ID 32371-8
    ISSN 0918-2918 ; 0021-5120
    ISSN 0918-2918 ; 0021-5120
    DOI 10.2169/internalmedicine.44.1027
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: [Myotonic disorder and channelopathy].

    Kurihara, Teruyuki

    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine

    2003  Band 93, Heft 3, Seite(n) 510–514

    Mesh-Begriff(e) Animals ; Chloride Channels/genetics ; Dehydroepiandrosterone Sulfate/administration & dosage ; Humans ; Mutation ; Myotonic Disorders/drug therapy ; Myotonic Disorders/etiology ; Sodium Channel Blockers/therapeutic use ; Sodium Channels/genetics
    Chemische Substanzen Chloride Channels ; Sodium Channel Blockers ; Sodium Channels ; Dehydroepiandrosterone Sulfate (57B09Q7FJR)
    Sprache Japanisch
    Erscheinungsdatum 2003-07-08
    Erscheinungsland Japan
    Dokumenttyp Journal Article ; Review
    ZDB-ID 952816-7
    ISSN 1883-2083 ; 0021-5384
    ISSN (online) 1883-2083
    ISSN 0021-5384
    DOI 10.2169/naika.93.510
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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