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Buch ; Online: Advanced Immunization Technologies for Next Generation Vaccines

Medaglini, Donata / Rappuoli, Rino / Andersen, Peter / Lewis, David J. M.

2020

Schlagwörter	Medicine ; Immunology ; ADITEC ; immunization technologies ; vaccines ; adjuvants ; vaccine vectors ; systems vaccinology ; human immunology
Umfang	1 electronic resource (296 pages)
Verlag	Frontiers Media SA
Dokumenttyp	Buch ; Online
Anmerkung	English ; Open Access
HBZ-ID	HT021231134
ISBN	9782889639311 ; 2889639312
Datenquelle	ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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Artikel ; Online: A goldilocks amount of H3K27me3.

Reich, Tyler J / Lewis, Peter W

Nature chemical biology

2023 Band 19, Heft 9, Seite(n) 1046–1047

Sprache	Englisch
Erscheinungsdatum	2023-03-10
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2202962-X
ISSN	1552-4469 ; 1552-4450
ISSN (online)	1552-4469
ISSN	1552-4450
DOI	10.1038/s41589-023-01295-5
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 6251: Hefte anzeigen			Standort: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Artikel ; Online: Polymerase Chain Reaction of Plasma and Bronchoalveolar Lavage Fluid for Diagnosing Invasive Aspergillosis.

White, P Lewis / Donnelly, J Peter

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

2023 Band 77, Heft 9, Seite(n) 1291–1293

Mesh-Begriff(e)	Humans ; Bronchoalveolar Lavage Fluid ; Aspergillosis/diagnosis ; Aspergillus/genetics ; Mannans/blood ; Polymerase Chain Reaction ; Cell-Free Nucleic Acids
Chemische Substanzen	galactomannan (11078-30-1) ; Mannans ; Cell-Free Nucleic Acids
Sprache	Englisch
Erscheinungsdatum	2023-07-14
Erscheinungsland	United States
Dokumenttyp	Editorial ; Comment
ZDB-ID	1099781-7
ISSN	1537-6591 ; 1058-4838
ISSN (online)	1537-6591
ISSN	1058-4838
DOI	10.1093/cid/ciad421
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Cardiopulmonary resuscitation and basic life support guidelines for people with disability: a scoping review.

Deegan, Elisha / Lewis, Peter / Wilson, Nathan J / Pullin, Laynie H

Disability and rehabilitation

2024 , Seite(n) 1–7

Abstract: Purpose: To explore literature, policies or procedures available to care providers on how to deliver CPR and BLS to people with a disability, for whom the current standard guidelines are not fit for purpose.: Material and methods: A scoping review ... ...

Abstract	Purpose: To explore literature, policies or procedures available to care providers on how to deliver CPR and BLS to people with a disability, for whom the current standard guidelines are not fit for purpose. Material and methods: A scoping review was conducted using four databases, namely, CINHAL, PubMed, Scopus, Medline and Google Scholar. Keywords used included, disab, wheelchairs, cardiopulmonary, resuscitation, "basic life support", life support care, and bystander CPR. 1119 papers were retrieved and 1043 were screened following removal of 76 for duplication. 18 full text articles were reviewed and 5 met the inclusion criteria. Results:* The five articles were from three counties and included one case study, three expert opinion papers and one intervention study. Four of the papers advocated in favour of improved CPR and BLS guidelines and three of the papers discussed techniques and ideas for supplementation of standard CPR and BLS. Conclusion: The scoping review has uncovered a paucity of evidence explaining delivery of CPR and BLS for people with disability and highlights the need for further research. In the absence of further evidence, it is reasonable for educators to provide ideas and discussion about supplementing CPR and BLS for people with disability to carers.
Sprache	Englisch
Erscheinungsdatum	2024-04-09
Erscheinungsland	England
Dokumenttyp	Journal Article ; Review
ZDB-ID	1104775-6
ISSN	1464-5165 ; 0963-8288
ISSN (online)	1464-5165
ISSN	0963-8288
DOI	10.1080/09638288.2024.2337098
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Animal deception and the content of signals.

Fallis, Don / Lewis, Peter J

Studies in history and philosophy of science

2021 Band 87, Seite(n) 114–124

Abstract: In cases of animal mimicry, the receiver of the signal learns the truth that he is either dealing with the real thing or with a mimic. Thus, despite being a prototypical example of animal deception, mimicry does not seem to qualify as deception on the ... ...

Abstract	In cases of animal mimicry, the receiver of the signal learns the truth that he is either dealing with the real thing or with a mimic. Thus, despite being a prototypical example of animal deception, mimicry does not seem to qualify as deception on the traditional definition, since the receiver is not actually misled. We offer a new account of propositional content in sender-receiver games that explains how the receiver is misled (and deceived) by mimicry. We show that previous accounts of deception, and of propositional content, give incorrect results about whether certain signals are deceptive.
Mesh-Begriff(e)	Animals ; Deception ; Learning ; Male
Sprache	Englisch
Erscheinungsdatum	2021-04-10
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	202358-1
ISSN	1879-2510 ; 0039-3681
ISSN (online)	1879-2510
ISSN	0039-3681
DOI	10.1016/j.shpsa.2021.03.004
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Increasing radial growth in old-growth high-elevation conifers in Southern California, USA, during the exceptional "hot drought" of 2000-2020.

Knapp, Paul A / Soulé, Peter T / Mitchell, Tyler J / Catherwood, Avery A / Lewis, Hunter S

International journal of biometeorology

2024 Band 68, Heft 4, Seite(n) 743–748

Abstract: Hot droughts, droughts attributed to below-average precipitation and exceptional warmth, are increasingly common in the twenty-first century, yet little is known about their effect on coniferous tree growth because of their historical rarity. In much of ... ...

Abstract	Hot droughts, droughts attributed to below-average precipitation and exceptional warmth, are increasingly common in the twenty-first century, yet little is known about their effect on coniferous tree growth because of their historical rarity. In much of the American West, including California, radial tree growth is principally driven by precipitation, and narrow ring widths are typically associated with either drier or drought conditions. However, for species growing at high elevations (e.g., Larix lyalli, Pinus albicaulis), growth can be closely aligned with above-average temperatures with maximum growth coinciding with meteorological drought, suggesting that the growth effects of drought span from adverse to beneficial depending on location. Here, we compare radial growth responses of three high-elevation old-growth pines (Pinus jeffreyi, P. lambertiana, and P. contorta) growing in the San Jacinto Mountains, California, during a twenty-first-century hot drought (2000-2020) largely caused by exceptional warmth and a twentieth-century drought (1959-1966) principally driven by precipitation deficits. Mean radial growth during the hot drought was 12% above average while 18% below average during the mid-century drought illustrating that the consequences of environmental stress exhibit spatiotemporal variability. We conclude that the effects of hot droughts on tree growth in high-elevation forests may produce responses different than what is commonly associated with extended dry periods for much of western North America's forested lands at lower elevational ranges and likely applies to other mountainous regions (e.g., Mediterranean Europe) defined by summer-dry conditions. Thus, the climatological/biological interactions discovered in Southern California may offer clues to the unique nature of high-elevation forested ecosystems globally.
Mesh-Begriff(e)	Ecosystem ; Droughts ; Pinus/physiology ; Forests ; California
Sprache	Englisch
Erscheinungsdatum	2024-01-12
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	280324-0
ISSN	1432-1254 ; 0020-7128
ISSN (online)	1432-1254
ISSN	0020-7128
DOI	10.1007/s00484-024-02619-3
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Multiplexing Autoradiography.

Lewis, David Y

Methods in molecular biology (Clifton, N.J.)

2023 Band 2729, Seite(n) 423–439

Abstract: ... technique that has several key advantages for the validation of PET radiotracers. Using autoradiography ...

Abstract	Autoradiography, the direct imaging of radioactive distribution in tissue sections, is a powerful technique that has several key advantages for the validation of PET radiotracers. Using autoradiography, we can localize radiotracer uptake to neighbours of cells, and when multiplexed with additional radiotracers, fluorescent probes, or in situ tissue analysis, autoradiography can help to characterize the mechanism of radiotracer uptake and assess functional heterogeneity in tissue. In this chapter, the author outlines the basic ex vivo autoradiography protocol and shows how it can be multiplexed using dual radionuclides
Mesh-Begriff(e)	Positron-Emission Tomography/methods ; Autoradiography ; Radioisotopes ; Radiopharmaceuticals ; Fluorescent Dyes ; Fluorine Radioisotopes
Chemische Substanzen	Radioisotopes ; Radiopharmaceuticals ; Fluorescent Dyes ; Fluorine Radioisotopes
Sprache	Englisch
Erscheinungsdatum	2023-11-25
Erscheinungsland	United States
Dokumenttyp	Journal Article
ISSN	1940-6029
ISSN (online)	1940-6029
DOI	10.1007/978-1-0716-3499-8_24
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Cardiopulmonary resuscitation and basic life support for people with atypical chest shapes and wheelchair users: Toward supplemented education and emergency management plans.

Deegan, Elisha / Wilson, Nathan J / Pullin, Laynie H / Lewis, Peter

Disability and health journal

2023 Band 16, Heft 4, Seite(n) 101501

Abstract: This article explores current practice issues in basic life support (BLS) and cardiopulmonary resuscitation (CPR) delivery for people with disability and poses recommendations for development of education and training where specialist nurses and other ... ...

Abstract	This article explores current practice issues in basic life support (BLS) and cardiopulmonary resuscitation (CPR) delivery for people with disability and poses recommendations for development of education and training where specialist nurses and other health professionals can facilitate BLS and CPR techniques catering for people with atypical chest shapes wheelchair users and people at high risk of choking. People with a disability are at higher risk of premature and unexpected death. At present there is a significant gap in knowledge about how to deliver optimal BLS or CPR to people with atypical chest shapes wheelchair users and people at high risk of choking. This leave carers to augment guidelines during emergency situations. Introduction of supplemented BLS and CPR together with development of emergency care plans for people with disability could reduce the number of people with disability dying premature or preventable deaths.
Mesh-Begriff(e)	Humans ; Cardiopulmonary Resuscitation/education ; Cardiopulmonary Resuscitation/methods ; Disabled Persons ; Educational Status ; Health Personnel ; Wheelchairs
Sprache	Englisch
Erscheinungsdatum	2023-06-29
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2414615-8
ISSN	1876-7583 ; 1936-6574
ISSN (online)	1876-7583
ISSN	1936-6574
DOI	10.1016/j.dhjo.2023.101501
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Becoming a non-resident father: Marginalised through distress, disadvantage and disempowerment.

Violi, Dominic / Lewis, Peter / Kwok, Cannas / Wilson, Nathan J

Health promotion journal of Australia : official journal of Australian Association of Health Promotion Professionals

2023 Band 34, Heft 4, Seite(n) 714–722

Abstract: Issue addressed: Becoming a non-resident father through divorce is stressful and this often results in compromised mental health and well-being. Non-resident fathers' mental well-being has been measured at very low levels which may require clinical ... ...

Abstract	Issue addressed: Becoming a non-resident father through divorce is stressful and this often results in compromised mental health and well-being. Non-resident fathers' mental well-being has been measured at very low levels which may require clinical treatment, especially when correlated with child access and family court issues. A United Nations report highlighted how non-resident fathers may be marginalised, but to date, limited literature considers the lives of non-resident fathers from their own perspective and reflecting their own voice and it has been claimed that as fathers are often absent from parenting research, this absence, they are not heard. The aim of this paper was to identify how non-resident fathers' interactions with legal and welfare services and ex-partners may result in their marginalisation and affect their mental health. Methods: In-depth interviews with open-ended questions were conducted with 19 non-resident fathers, both long term, newly divorced or in the divorce process, so as to capture a long range view of their experiences. Thematic Analysis was used for data analysis and the generation of the themes. Results: Three themes emerged from the data: (1) Becoming a non-resident father with two sub themes; (2) Being in a state of distress, with three sub-themes and (3) Managing distress and seeking help, with two sub-themes. Participants reported a lack of agency, lack of power in decision making and a lack of social and financial resources all contributing to the deterioration in their self-reported experiences of mental health. This impact was highlighted by the number of participants who undertook counselling or psychological assistance to deal with their perceived marginalisation, feeling of invisibility and disempowerment. Conclusions: The implications of marginalisation for non-resident fathers' mental health, as outlined by the participants, are discussed regarding the impact of becoming a non-resident father, legal aspects, welfare service experiences and relationship with ex-partner. The chronic stress experienced by non-resident fathers who often find themselves in a situation which is difficult to resolve without major compromises to their desired outcomes must be recognised. So what: One means of achieving better mental health for non-resident fathers is to address the impact of marginalisation and lack of agency and that court processes are resolved swiftly with a view to increasing non-resident father's agency in post-divorce decision making.
Mesh-Begriff(e)	Male ; Child ; Humans ; Fathers/psychology ; Mental Health ; Psychological Well-Being ; Parenting/psychology ; Self Report
Sprache	Englisch
Erscheinungsdatum	2023-10-01
Erscheinungsland	Australia
Dokumenttyp	Journal Article
ZDB-ID	2250864-8
ISSN	2201-1617 ; 1036-1073
ISSN (online)	2201-1617
ISSN	1036-1073
DOI	10.1002/hpja.810
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Inhibition of N-type calcium channels by phenoxyaniline and sulfonamide analogues.

Bispat, Anjie S / Cardoso, Fernanda C / Hasan, Md Mahadhi / Dongol, Yashad / Wilcox, Ricki / Lewis, Richard J / Duggan, Peter J / Tuck, Kellie L

RSC medicinal chemistry

2024 Band 15, Heft 3, Seite(n) 916–936

Abstract: Building on previous investigations, structural modifications to the neuronal calcium ion channel blocker MONIRO-1 and related compounds were conducted that included replacement of the amide linker with an aniline and isosteric sulfonamide moiety, and ... ...

Abstract	Building on previous investigations, structural modifications to the neuronal calcium ion channel blocker MONIRO-1 and related compounds were conducted that included replacement of the amide linker with an aniline and isosteric sulfonamide moiety, and the previously used strategy of substitution of the guanidinium group with less hydrophilic amine functionalities. A comprehensive SAR study revealed a number of phenoxyaniline and sulfonamide compounds that were more potent or had similar potency for the Ca
Sprache	Englisch
Erscheinungsdatum	2024-01-31
Erscheinungsland	England
Dokumenttyp	Journal Article
ISSN	2632-8682
ISSN (online)	2632-8682
DOI	10.1039/d3md00714f
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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