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  1. Artikel: Effect of Subanaesthetic Dose of Ketamine on Pneumoperitoneal Response and Clinical Recovery in Patients Undergoing Laparoscopy.

    Rajarajan, Swaminathan Veerasamy / Alarasan, Arun Kumar / Subramaniam, Anand / Mathews, Lailu

    Turkish journal of anaesthesiology and reanimation

    2022  Band 50, Heft 3, Seite(n) 212–218

    Abstract: Objective: Although suppression of intraperitoneal gas insufflation response is possible with a higher dose of opioids, sedatives, and inha- lational agents, delayed emergence and poor clinical recovery are still a matter of concern. Here our primary ... ...

    Abstract Objective: Although suppression of intraperitoneal gas insufflation response is possible with a higher dose of opioids, sedatives, and inha- lational agents, delayed emergence and poor clinical recovery are still a matter of concern. Here our primary aim was to assess the quality of recovery and the secondary aim includes postinsufflation response, postoperative pain intensity, total opioid requirement, and looking for adverse effects, if any.
    Methods: This prospective randomized double-blinded controlled study was conducted among 75 American Society of Anesthesiologist physical status I and II patients scheduled for laparoscopic surgeries under general anaesthesia. Group 1 received injection tramadol 1 mg kg-1 iv-1 5 minutes after intubation. Similarly, groups 2 and 3 received 0.25 mg kg-1 and 0.5 mg kg-1 injection of ketamine iv, respectively. Intraperitoneal insufflation response was observed from the beginning of insufflation till 15 minutes. Clinical recovery was measured in terms of vigilance, cognition, orientation, and comfort. Postoperative pain intensity was assessed at varying movement activities using numerical rating scale pain score and with the total opioid requirement. The collected data were analyzed using three-way ANOVA.
    Results: Groups 1 and 2 had a fair clinical recovery. Postoperative pain intensity was least in group 2, and the postinsufflation mean arterial pressure was higher in groups 1 and 3. A total of 32% of participants had delirium in group 3.
    Conclusions: Clinical recovery and perioperative analgesia were better in ketamine group (0.25 mg kg-1) without any perturbations in intra- operative pneumoperitoneal response. Hence it can be considered an optimal adjuvant in laparoscopic surgeries.
    Sprache Englisch
    Erscheinungsdatum 2022-08-05
    Erscheinungsland Turkey
    Dokumenttyp Journal Article
    ISSN 2667-677X
    ISSN 2667-677X
    DOI 10.5152/TJAR.2022.21066
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Dr. Rajaratinam Karnan Kalyan Singh

    Mathews Lailu

    Annals of Cardiac Anaesthesia, Vol 14, Iss 2, Pp 169-

    2011  Band 169

    Schlagwörter Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Sprache Englisch
    Erscheinungsdatum 2011-01-01T00:00:00Z
    Verlag Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel: Potential threat of meningitis from ampoule impurities: Prevention is always better than cure!

    Muthiah, Thilaka / Mathews, Lailu / Sivashankar, K R

    Indian journal of anaesthesia

    2016  Band 60, Heft 2, Seite(n) 145–146

    Sprache Englisch
    Erscheinungsdatum 2016-03-24
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 412570-8
    ISSN 0019-5049
    ISSN 0019-5049
    DOI 10.4103/0019-5049.176280
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Potential threat of meningitis from ampoule impurities

    Thilaka Muthiah / Lailu Mathews / K R Sivashankar

    Indian Journal of Anaesthesia, Vol 60, Iss 2, Pp 145-

    Prevention is always better than cure!

    2016  Band 146

    Schlagwörter Anesthesiology ; RD78.3-87.3 ; Surgery ; RD1-811 ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2016-01-01T00:00:00Z
    Verlag Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Intravenous labetolol in treating hypertensive crisis following dexmedetomidine infusion for procedural sedation.

    Muthiah, Thilaka / Moni, Amarnath / Mathews, Lailu / Balaji, Sudarshan

    Journal of clinical anesthesia

    2016  Band 29, Seite(n) 30–32

    Abstract: Dexmedetomidine is widely used for procedural sedation because of its unique combination of sedation, analgesia, and anxiolysis with minimal respiratory depression. Transient hypertension has been reported during the use of dexmedetomidine which is ... ...

    Abstract Dexmedetomidine is widely used for procedural sedation because of its unique combination of sedation, analgesia, and anxiolysis with minimal respiratory depression. Transient hypertension has been reported during the use of dexmedetomidine which is usually benign and is taken over by the hypotensive response on continuing the infusion. We report a case of hypertensive crisis following dexmedetomidine infusion used for procedural sedation, necessitating discontinuation of the infusion and treatment of hypertension. The dilemmas involved in treating hypertension caused by dexmedetomidine are discussed.
    Mesh-Begriff(e) Adrenergic alpha-2 Receptor Agonists/adverse effects ; Adult ; Antihypertensive Agents/therapeutic use ; Conscious Sedation/adverse effects ; Dexmedetomidine/adverse effects ; Humans ; Hypertension/drug therapy ; Hypnotics and Sedatives/adverse effects ; Labetalol/therapeutic use ; Male
    Chemische Substanzen Adrenergic alpha-2 Receptor Agonists ; Antihypertensive Agents ; Hypnotics and Sedatives ; Dexmedetomidine (67VB76HONO) ; Labetalol (R5H8897N95)
    Sprache Englisch
    Erscheinungsdatum 2016-03
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 1011618-7
    ISSN 1873-4529 ; 0952-8180
    ISSN (online) 1873-4529
    ISSN 0952-8180
    DOI 10.1016/j.jclinane.2015.10.011
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 2622: Hefte anzeigen Standort:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Artikel ; Online: Cardiac output monitoring

    Mathews Lailu / Singh Kalyan

    Annals of Cardiac Anaesthesia, Vol 11, Iss 1, Pp 56-

    2008  Band 68

    Abstract: Minimally invasive and non-invasive methods of estimation of cardiac output (CO) were developed to overcome the limitations of invasive nature of pulmonary artery catheterization (PAC) and direct Fick method used for the measurement of stroke volume (SV). ...

    Abstract Minimally invasive and non-invasive methods of estimation of cardiac output (CO) were developed to overcome the limitations of invasive nature of pulmonary artery catheterization (PAC) and direct Fick method used for the measurement of stroke volume (SV). The important minimally invasive techniques available are: oesophageal Doppler monitoring (ODM), the derivative Fick method (using partial carbon dioxide (CO 2 ) breathing), transpulmonary thermodilution, lithium indicator dilution, pulse contour and pulse power analysis. Impedance cardiography is probably the only non-invasive technique in true sense. It provides information about haemodynamic status without the risk, cost and skill associated with the other invasive or minimally invasive techniques. It is important to understand what is really being measured and what assumptions and calculations have been incorporated with respect to a monitoring device. Understanding the basic principles of the above techniques as well as their advantages and limitations may be useful. In addition, the clinical validation of new techniques is necessary to convince that these new tools provide reliable measurements. In this review the physics behind the working of ODM, partial CO 2 breathing, transpulmonary thermodilution and lithium dilution techniques are dealt with. The physical and the physiological aspects underlying the pulse contour and pulse power analyses, various pulse contour techniques, their development, advantages and limitations are also covered. The principle of thoracic bioimpedance along with computation of CO from changes in thoracic impedance is explained. The purpose of the review is to help us minimize the dogmatic nature of practice favouring one technique or the other.
    Schlagwörter Cardiac output ; impedance cardiography ; lithium dilution ; oesophageal doppler monitoring ; partial CO 2 breathing ; pulse contour analysis ; transpulmonary thermodilution ; Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Cardiovascular ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Sprache Englisch
    Erscheinungsdatum 2008-01-01T00:00:00Z
    Verlag Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel: Cardiac output monitoring.

    Mathews, Lailu / Singh, R K Kalyan

    Annals of cardiac anaesthesia

    2008  Band 11, Heft 1, Seite(n) 56–68

    Abstract: Minimally invasive and non-invasive methods of estimation of cardiac output (CO) were developed to overcome the limitations of invasive nature of pulmonary artery catheterization (PAC) and direct Fick method used for the measurement of stroke volume (SV). ...

    Abstract Minimally invasive and non-invasive methods of estimation of cardiac output (CO) were developed to overcome the limitations of invasive nature of pulmonary artery catheterization (PAC) and direct Fick method used for the measurement of stroke volume (SV). The important minimally invasive techniques available are: oesophageal Doppler monitoring (ODM), the derivative Fick method (using partial carbon dioxide (CO2 ) breathing), transpulmonary thermodilution, lithium indicator dilution, pulse contour and pulse power analysis. Impedance cardiography is probably the only non-invasive technique in true sense. It provides information about haemodynamic status without the risk, cost and skill associated with the other invasive or minimally invasive techniques. It is important to understand what is really being measured and what assumptions and calculations have been incorporated with respect to a monitoring device. Understanding the basic principles of the above techniques as well as their advantages and limitations may be useful. In addition, the clinical validation of new techniques is necessary to convince that these new tools provide reliable measurements. In this review the physics behind the working of ODM, partial CO2 breathing, transpulmonary thermodilution and lithium dilution techniques are dealt with. The physical and the physiological aspects underlying the pulse contour and pulse power analyses, various pulse contour techniques, their development, advantages and limitations are also covered. The principle of thoracic bioimpedance along with computation of CO from changes in thoracic impedance is explained. The purpose of the review is to help us minimize the dogmatic nature of practice favouring one technique or the other.
    Mesh-Begriff(e) Algorithms ; Carbon Dioxide/analysis ; Cardiac Output/physiology ; Echocardiography, Doppler ; Humans ; Lithium ; Monitoring, Intraoperative/instrumentation ; Monitoring, Intraoperative/methods ; Pulse ; Regional Blood Flow/physiology ; Thermodilution
    Chemische Substanzen Carbon Dioxide (142M471B3J) ; Lithium (9FN79X2M3F)
    Sprache Englisch
    Erscheinungsdatum 2008-01-02
    Erscheinungsland India
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2106866-5
    ISSN 0974-5181 ; 0971-9784
    ISSN (online) 0974-5181
    ISSN 0971-9784
    DOI 10.4103/0971-9784.38455
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Intraoperative cardiac arrest--successful resuscitation with open chest cardiac compression.

    Mathews, Lailu / Cherian, Sanjay / Singh, R K Kalyan

    Annals of cardiac anaesthesia

    2006  Band 9, Heft 2, Seite(n) 141–143

    Sprache Englisch
    Erscheinungsdatum 2006-07
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2106866-5
    ISSN 0974-5181 ; 0971-9784
    ISSN (online) 0974-5181
    ISSN 0971-9784
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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