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  1. Artikel ; Online: ESAs in transplant anemia: one size does not "fit all".

    Mehrotra, Anita

    Journal of the American Society of Nephrology : JASN

    2012  Band 23, Heft 2, Seite(n) 192–193

    Mesh-Begriff(e) Anemia/drug therapy ; Erythropoietin/therapeutic use ; Female ; Humans ; Kidney Diseases/prevention & control ; Kidney Transplantation/adverse effects ; Male ; Recombinant Proteins/therapeutic use
    Chemische Substanzen Recombinant Proteins ; epoetin beta ; Erythropoietin (11096-26-7)
    Sprache Englisch
    Erscheinungsdatum 2012-01-12
    Erscheinungsland United States
    Dokumenttyp Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2011121220
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Usefulness of Thromboelastography for Perioperative Evaluation of Hemostatic Profile in Patients with Primary Brain Tumors Undergoing Surgery.

    Khatri, Vikalp / Hemlata / Mehrotra, Megha Kohli / Kohli, Monica / Malik, Anita / Verma, Anupam

    Anesthesia, essays and researches

    2022  Band 15, Heft 3, Seite(n) 279–284

    Abstract: Context: Hemostatic abnormalities are more common in patients with brain tumors than systemic malignant diseases. Conventional coagulation tests (CCT) are poor assays for dynamic assessment of clot strength in whole blood. Thromboelastography (TEG) ... ...

    Abstract Context: Hemostatic abnormalities are more common in patients with brain tumors than systemic malignant diseases. Conventional coagulation tests (CCT) are poor assays for dynamic assessment of clot strength in whole blood. Thromboelastography (TEG) gives us detailed information on the dynamics of clot development, stabilization, and dissolution reflecting
    Aims: This study aimed to investigate the temporal trends in hemostatic profile occurring during surgery for primary brain tumors, using a combination of TEG and CCT, and to assess perioperative blood component support.
    Subjects and methods: A prospective, observational study was done on 40 patients with primary brain tumors larger than 4 cm in maximum diameter on computed tomography or magnetic resonance imaging. The tests (TEG and CCT [PT, INR, activated partial thromboplastin time, and platelet count]) were performed preoperatively (on the day of surgery), intraoperatively (2 h into surgery), and postoperatively (the day after surgery).
    Statistical analysis: SPSS Version 21.0 statistical analysis software was used.
    Results: We found a universal trend toward hypercoagulability (persistent decrease in R-time, K-time and increase in MA, α-angle, Coagulation Index) in all the TEG parameters measured intraoperatively and postoperatively even though the values were within normal limits. Results of CCT had poor correlation with TEG parameters. The mean intraoperative blood loss was 737.7 ± 185.6 mL, for which PRBC was transfused in 17 patients, FFP in 13, but no platelet transfusion was done intraoperatively.
    Conclusions: We found a trend toward hypercoagulability in our study in intraoperative and postoperative period using TEG which was not evident on CCT. TEG was a useful diagnostic tool to identify coagulation abnormalities and to guide perioperative blood transfusion.
    Sprache Englisch
    Erscheinungsdatum 2022-02-07
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2626233-2
    ISSN 2229-7685 ; 0259-1162
    ISSN (online) 2229-7685
    ISSN 0259-1162
    DOI 10.4103/aer.aer_136_21
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: To Host or Not to Host? A Comparison Study on the Long-Run Impact of the Olympic Games

    Anita Mehrotra

    Michigan Journal of Business, Vol 5, Iss 2, Pp 61-

    2012  Band 92

    Abstract: Macroeconomic research on sporting mega-events, like the Olympic Games, often focuses on the short-run economic impact of individual countries. In this paper, I explore the long-run effect of the Olympics on host countries, in general. I analyze hosts in ...

    Abstract Macroeconomic research on sporting mega-events, like the Olympic Games, often focuses on the short-run economic impact of individual countries. In this paper, I explore the long-run effect of the Olympics on host countries, in general. I analyze hosts in relation to "runner-up" countries, i.e. countries that come in second to the hosts in the bidding process. Upon rectifying anomalies in the data set and including control variables for the initial state of the economy and population, I find that hosts' long-run GDP per capita (GDPpc) is negative in comparison to runner-up countries' at a statistically significant level. This suggests that a one-time spike in government expenditure may lead to long-run detrimental effects: a "reverse multiplier effect" perpetuates the fall in investment demand and consumption levels back to pre-Olympic levels. My results extend the view that individual countries experience a negative economic impact, to the group of host countries in general.
    Schlagwörter Business ; HF5001-6182 ; Commerce ; HF1-6182 ; Social Sciences ; H ; DOAJ:Business and Management ; DOAJ:Business and Economics
    Thema/Rubrik (Code) 300
    Sprache Englisch
    Erscheinungsdatum 2012-09-01T00:00:00Z
    Verlag University of Michigan
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel: Maternal Near Miss: Unraveling Our Experience in the Tertiary Care Hospital of Andaman and Nicobar Islands.

    Sharma, Charu / Yadav, Anita / Mehrotra, Manju / Saha, Mrinmoy Kumar / Tambe, Rupali R

    Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

    2021  Band 46, Heft 1, Seite(n) 35–39

    Abstract: Context: Women who survive life-threatening complications related to pregnancy and delivery have many common aspects with those who die of such complications. This similarity brought forward the near miss concept in maternal health. Analysis of the ... ...

    Abstract Context: Women who survive life-threatening complications related to pregnancy and delivery have many common aspects with those who die of such complications. This similarity brought forward the near miss concept in maternal health. Analysis of the similarities, differences, and the relationship between these two groups of women provide a complete assessment of quality of maternal health care.
    Aims: The aim of this study is to assess the baseline indices of maternal near miss (MNM) and analyze the quality of care at a tertiary care center in Andaman and Nicobar Islands.
    Settings and design: Facility-based, cross-sectional study.
    Subjects and methods: The study was conducted for a period of 18 months from January 1, 2015, to August 31, 2016. Cases, who met the World Health Organization (WHO) criteria of severe obstetric morbidity, were included and followed up during their hospital stay and till their discharge or death. Quality of maternal health care was assessed through the WHO near-miss criteria and criterion-based clinical audit methodology.
    Statistical analysis used: Descriptive statistics using mean and percentages and Student's
    Results: Among 4720 women who delivered in our hospital, there were 4677 live births, 52 patients were near miss, and there were 9 maternal deaths. The MNM incidence ratio was 11.11%, the MNM mortality ratio was 5.77, and the mortality index 14.75%. The most common cause of maternal morbidity was hemorrhage followed by hypertensive disorders.
    Conclusions: Improving referral systems, effective use of critical care, and evidence-based interventions can potentially reduce severe maternal outcomes.
    Sprache Englisch
    Erscheinungsdatum 2021-03-01
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2085330-0
    ISSN 1998-3581 ; 0970-0218
    ISSN (online) 1998-3581
    ISSN 0970-0218
    DOI 10.4103/ijcm.IJCM_145_20
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Maternal near miss

    Charu Sharma / Anita Yadav / Manju Mehrotra / Mrinmoy Kumar Saha / Rupali R Tambe

    Indian Journal of Community Medicine, Vol 46, Iss 1, Pp 35-

    Unraveling our experience in the tertiary care hospital of Andaman and Nicobar Islands

    2021  Band 39

    Abstract: Context: Women who survive life-threatening complications related to pregnancy and delivery have many common aspects with those who die of such complications. This similarity brought forward the near miss concept in maternal health. Analysis of the ... ...

    Abstract Context: Women who survive life-threatening complications related to pregnancy and delivery have many common aspects with those who die of such complications. This similarity brought forward the near miss concept in maternal health. Analysis of the similarities, differences, and the relationship between these two groups of women provide a complete assessment of quality of maternal health care. Aims: The aim of this study is to assess the baseline indices of maternal near miss (MNM) and analyze the quality of care at a tertiary care center in Andaman and Nicobar Islands. Settings and Design: Facility-based, cross-sectional study. Subjects and Methods: The study was conducted for a period of 18 months from January 1, 2015, to August 31, 2016. Cases, who met the World Health Organization (WHO) criteria of severe obstetric morbidity, were included and followed up during their hospital stay and till their discharge or death. Quality of maternal health care was assessed through the WHO near-miss criteria and criterion-based clinical audit methodology. Statistical Analysis Used: Descriptive statistics using mean and percentages and Student's t-test were used. Results: Among 4720 women who delivered in our hospital, there were 4677 live births, 52 patients were near miss, and there were 9 maternal deaths. The MNM incidence ratio was 11.11%, the MNM mortality ratio was 5.77, and the mortality index 14.75%. The most common cause of maternal morbidity was hemorrhage followed by hypertensive disorders. Conclusions: Improving referral systems, effective use of critical care, and evidence-based interventions can potentially reduce severe maternal outcomes.
    Schlagwörter intensive care unit ; maternal near miss ; morbidity ; mortality index ; Public aspects of medicine ; RA1-1270
    Thema/Rubrik (Code) 360
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Wolters Kluwer Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: B cells and kidney transplantation: beyond antibodies.

    Mehrotra, Anita / Heeger, Peter S

    Journal of the American Society of Nephrology : JASN

    2014  Band 25, Heft 7, Seite(n) 1373–1374

    Mesh-Begriff(e) B-Lymphocytes, Regulatory/immunology ; Female ; Humans ; Interleukin-10/immunology ; Kidney Neoplasms/immunology ; Male ; Tumor Necrosis Factor-alpha/immunology
    Chemische Substanzen Tumor Necrosis Factor-alpha ; Interleukin-10 (130068-27-8)
    Sprache Englisch
    Erscheinungsdatum 2014-03-07
    Erscheinungsland United States
    Dokumenttyp Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2014020132
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Erratum to: Nutritional vitamin D supplementation and health-related outcomes in hemodialysis patients: a protocol for a systematic review and meta-analysis.

    Mehrotra, Anita / Leung, Wai-Yin / Joson, Tannia

    Systematic reviews

    2015  Band 4, Seite(n) 106

    Sprache Englisch
    Erscheinungsdatum 2015-08-11
    Erscheinungsland England
    Dokumenttyp Published Erratum
    ZDB-ID 2662257-9
    ISSN 2046-4053 ; 2046-4053
    ISSN (online) 2046-4053
    ISSN 2046-4053
    DOI 10.1186/s13643-015-0086-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Field-Based Evaluation of Rice Genotypes for Enhanced Growth, Yield Attributes, Yield and Grain Yield Efficiency Index in Irrigated Lowlands of the Indo-Gangetic Plains

    Sandeep Gawdiya / Dinesh Kumar / Yashbir S. Shivay / Arti Bhatia / Shweta Mehrotra / Mandapelli Sharath Chandra / Anita Kumawat / Rajesh Kumar / Adam H. Price / Nandula Raghuram / Himanshu Pathak / Mark A. Sutton

    Sustainability, Vol 15, Iss 8793, p

    2023  Band 8793

    Abstract: Nitrogen (N) fertilizers are widely used worldwide to increase agricultural productivity. However, significant N losses contributing to air and water pollution ultimately reduce the nitrogen use efficiency (NUE) of crops. Numerous research studies have ... ...

    Abstract Nitrogen (N) fertilizers are widely used worldwide to increase agricultural productivity. However, significant N losses contributing to air and water pollution ultimately reduce the nitrogen use efficiency (NUE) of crops. Numerous research studies have emphasized the use of a low dose of N fertilizer, but few have focused on screening N-efficient rice genotypes. This study aimed to identify and screen ten rice genotypes that are N-use-efficient under different N fertilization treatments using the surface placement of neem-oil-coated urea: N 0 (control), N 60 (½ of recommended N), and N 120 (recommended N) for two consecutive years (2020 and 2021) under a split plot design. In both growing seasons, the application of N 120 yielded the highest panicles m −2 (PAN = 453), filled grains panicle −1 (FGP = 133), leaf area index (LAI = 5.47), tillers m −2 (TILL = 541), grain yield t ha −1 (GY = 5.5) and harvest index (HI = 45.4%) by the genotype ‘Nidhi’, being closely followed by the genotype ‘Daya’. Four genotypes (‘Nidhi’, ‘Daya’, ‘PB 1728’ and ‘Nagina 22’), out of the ten genotypes evaluated, responded well to different fertilization treatments with N with respect to the grain yield efficiency index (GYEI ≥ 1). Regarding N fertilization, N 60 and N 120 recorded the highest increase in PAN (28.5%; 41.4%), FGP (29.5%; 39.3%), test weight (29.5%; 45.3%), LAI at 30 days after transplanting (DAT) (143.7%; 223.3%), and LAI at 60 DAT (61.6%; 70.1%) when compared with N 0 . Furthermore, the application of N 60 and N 120 improved GY and HI by 47.6% and 59.4%, and 3.4% and 6.2%, respectively, over N 0 . Nitrogen addition (N 60 and N 120 ) also significantly increased the chlorophyll content at 60 DAT (8.8%; 16.3%), TILL at 60 DAT (22.9%; 46.2%), TILL at harvest (28%; 41.4%), respectively, over N 0 . Overall, our research findings clearly indicate that ‘Nidhi’ and ‘Daya’ could be efficient candidates for improved nitrogen use, grain yield and GYEI in the Indo-Gangetic plains of India.
    Schlagwörter grain yield ; rice genotypes ; nitrogen fertilization ; grain yield efficiency index ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 333
    Sprache Englisch
    Erscheinungsdatum 2023-05-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Obstetric Cerebral Venous ThrombosisA Clinical Dilemma

    Charu Sharma / Anita Yadav / Shiv Shankar Singh / Manju Mehrotra / Avinash Prakash

    Journal of Clinical and Diagnostic Research, Vol 13, Iss 8, Pp QC10-QC

    2019  Band 13

    Abstract: Introduction: Cerebral Venous Thrombosis (CVT) is one of the important causes of stroke which is not very common. It has a varied clinical presentation and pathogenesis. It most often involves the superior sagittal sinus but may occur anywhere in the ... ...

    Abstract Introduction: Cerebral Venous Thrombosis (CVT) is one of the important causes of stroke which is not very common. It has a varied clinical presentation and pathogenesis. It most often involves the superior sagittal sinus but may occur anywhere in the cerebral venous circulation. Pregnancy and puerperium are in itself a high-risk factor for its occurrence. Aim: To assess the frequency of different clinical features, risk factors and prognostic outcome of patients diagnosed as CVT. Materials and Methods: A hospital based observational study was conducted in the Department of Obstetrics and Gynaecology and the Department of Medicine at Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar Islands, India, from January 2015 to December 2016. All cases of cerebrovascular accidents were followed and those diagnosed as CVT on the basis of Computed Tomogram (CT), Magnetic Resonance Imaging (MRI) and/or Magnetic Resonance Venogram (MRV) were included in the study, managed and followed till discharge from the hospital and at three months post-delivery. Means and percentages were used as statistical analysis. Results: Out of total of 4,767 deliveries in the study period, we found six cases of puerperal CVT. The incidence of puerperal CVT in our study population came out to be 125.8 per 100,000 deliveries. The mean age of women presenting with CVT was 23.6±3.204 years. The most common presenting symptom was headache (6/6, 100%) followed by seizure (4/6, 66.6%), hemiparesis (1/6), diplopia (1/6) and blindness (1/6). The most common area of infarct was superior sagittal sinus (6/6, 100%). The average period between the onset of symptoms and consultation was 1.8 days. Mortality at discharge was 16.6% (1/6). Conclusion: In CVT precise diagnosis is decisive as based on the diagnosis timely and suitable therapy can be started which can reverse the disease process.
    Schlagwörter empty delta sign ; heparin ; infarct ; magnetic resonance venography ; superior sagittal sinus ; Medicine ; R
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2019-08-01T00:00:00Z
    Verlag JCDR Research and Publications Private Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: "Out of Sight, Out of Mind": The Failed Renal Allograft as a Cause of ESA Resistance.

    Mehrotra, Anita / Tan, Judy A / Ames, Scott A

    Seminars in dialysis

    2015  Band 28, Heft 5, Seite(n) 530–532

    Abstract: Approximately 10% of patients treated with erythropoiesis-stimulating agents (ESAs) for the anemia of chronic kidney disease are unresponsive or relatively resistant to therapy. The etiology of this is usually linked to iron deficiency or an independent ... ...

    Abstract Approximately 10% of patients treated with erythropoiesis-stimulating agents (ESAs) for the anemia of chronic kidney disease are unresponsive or relatively resistant to therapy. The etiology of this is usually linked to iron deficiency or an independent underlying illness. We describe a hemodialysis patient with a failed renal transplant 1.5 years earlier, who developed progressive erythropoietin resistance and anemia without an apparent cause. He simultaneously developed nonspecific malaise and fatigue. By exclusion, the only possible cause of these signs and symptoms was inflammation from acute and chronic rejection in the retained failed renal allograft. Following pulse steroids and transplant nephrectomy, the patient's symptoms resolved and both his hemoglobin improved and his erythropoietin requirements decreased significantly. The patient never required a blood transfusion and was successfully relisted for a deceased donor renal transplant. Hence, inflammation from a retained transplant allograft may be an under-recognized cause of erythropoietin resistance in dialysis patients. Although transplant nephrectomy remains a controversial practice due to concerns of alloantibody production, it may be considered in patients with failed renal allografts and anemia refractory to treatment with ESAs.
    Mesh-Begriff(e) Adult ; Allografts ; Anemia/drug therapy ; Anemia/etiology ; Drug Resistance ; Graft Rejection/surgery ; Hematinics/therapeutic use ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Kidney Transplantation/adverse effects ; Male ; Nephrectomy ; Renal Dialysis/methods
    Chemische Substanzen Hematinics
    Sprache Englisch
    Erscheinungsdatum 2015-09
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1028193-9
    ISSN 1525-139X ; 0894-0959
    ISSN (online) 1525-139X
    ISSN 0894-0959
    DOI 10.1111/sdi.12401
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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