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Artikel ; Online: Avaliação dos conhecimentos, atitudes e medidas de prevenção contra a dengue na cidade de Senador Rui Palmeira/AL

Maria Regina Oliveira da Silva / Pedro Juvino de Souza Júnior / Claudimary Bispo dos Santos

Diversitas Journal, Vol 2, Iss

2017 Band 3

Abstract: ... se com este estudo avaliar o conhecimento, atitudes e medidas de prevenção da Dengue na cidade de Senador Rui ... prevention measures in the city of Senador Rui Palmeira, the state of Alagoas. The search is called based on ...

Abstract	RESUMO: A Dengue é uma arbovirose que está entre as problemáticas de saúde mais abordadas no Brasil e no mundo, causada pelo Flavivirus transmitido pelo mosquito-fêmea do gênero Aedes. Objetivou-se com este estudo avaliar o conhecimento, atitudes e medidas de prevenção da Dengue na cidade de Senador Rui Palmeira, interior do estado de Alagoas. A pesquisa denomina-se exploratória baseada em trabalho de campo que está em desenvolvimento na zona urbana do município supracitado com uma amostragem de 100 domicílios escolhidos aleatoriamente que serão visitados durante o ano de 2016. Estes dados correspondem a 56 domicílios visitados, onde foram observados 86% do gênero feminino, 30% possuem idades entre 18 e 29 anos e 63% não concluíram o ensino fundamental II. Podendo ser a falta de escolaridade e falta de consciência principal dificuldade para ações de educação em relação a Dengue. Com isso, 96% costumam armazenar água, devido ocorrer intermitência constante no sistema de abastecimento. Havia condições favoráveis para o desenvolvimento das larvas em 66% dos domicílios. Foi possível concluir que o grau de escolaridade e as condições socioeconômicas não afetam as atitudes e medidas de prevenção da Dengue, estando este um fator essencial para a elaboração de outras pesquisas na área. PALAVRAS - CHAVE: Educação, Saúde, Brasil. ABSTRACT: Dengue is an arbovirus which is among the health issues most discussed in Brazil and in the world, caused by flavivirus transmitted by the mosquito-female Aedes genus. This study aims to evaluate the knowledge, attitudes and Dengue prevention measures in the city of Senador Rui Palmeira, the state of Alagoas. The search is called based on exploratory field work that is under development in the urban area of the above municipality with a sample of 100 households randomly selected to be visited during the year 2016. This corresponds to 56 households visited, which were observed 86 % female, 30% are aged between 18 and 29 years and 63% have not completed primary education II. It may be a ...
Schlagwörter	Education ; L ; Science ; Q ; Social Sciences ; H
Sprache	Englisch
Erscheinungsdatum	2017-12-01T00:00:00Z
Verlag	Universidade Estadual de Alagoas
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Buch ; Online ; E-Book: Hydrogels for tissue engineering and regenerative medicine

Oliveira, Joaquim Miguel / Silva-Correia, Joana / Reis, Rui L.

from fundamentals to applications

2024

Abstract: Hydrogels for Tissue Engineering and Regenerative Medicine: From Fundaments to Applications provides the reader with a comprehensive, concise and thoroughly up-to-date resource on the different types of hydrogels in tissue engineering and regenerative ... ...

Verfasserangabe	edited by J. Miguel Oliveira, Joana Silva-Correia, and Rui L. Reis
Abstract	Hydrogels for Tissue Engineering and Regenerative Medicine: From Fundaments to Applications provides the reader with a comprehensive, concise and thoroughly up-to-date resource on the different types of hydrogels in tissue engineering and regenerative medicine. The book is divided into three main sections that describe biological activities and the structural and physicochemical properties of hydrogels, along with a wide range of applications, including their combination with emerging technologies. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this groundbreaking publication fills a gap in literature needed in the tissue engineering and regenerative medicine field.
Mesh-Begriff(e)	Hydrogels/therapeutic use. ; Tissue Engineering. ; Regenerative Medicine.
Schlagwörter	Tissue engineering ; Colloids/Therapeutic use.
Thema/Rubrik (Code)	621
Sprache	Englisch
Umfang	1 online resource (851 pages)
Ausgabenhinweis	First edition.
Verlag	Academic Press
Erscheinungsort	London
Dokumenttyp	Buch ; Online ; E-Book
Bemerkung	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
ISBN	0-12-824225-6 ; 9780128239483 ; 978-0-12-824225-4 ; 0128239484
Datenquelle	ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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Artikel ; Online: Single-Particle Plasmon Sensor to Monitor Proteolytic Activity in Real Time.

Oliveira-Silva, Rui / Wang, Yuyang / Nooteboom, Sjoerd W / Prazeres, Duarte M F / Paulo, Pedro M R / Zijlstra, Peter

ACS applied optical materials

2023 Band 1, Heft 10, Seite(n) 1661–1669

Abstract: We have established a label-free plasmonic platform that monitors proteolytic activity in real time. The sensor consists of a random array of gold nanorods that are functionalized with a design peptide that is specifically cleaved by thrombin, resulting ... ...

Abstract	We have established a label-free plasmonic platform that monitors proteolytic activity in real time. The sensor consists of a random array of gold nanorods that are functionalized with a design peptide that is specifically cleaved by thrombin, resulting in a blueshift of the longitudinal plasmon. By monitoring the plasmon of many individual nanorods, we determined thrombin's proteolytic activity in real time and inferred relevant kinetic parameters. Furthermore, a comparison to a kinetic model revealed that the plasmon shift is dictated by a competition between peptide cleavage and thrombin binding, which have opposing effects on the measured plasmon shift. The dynamic range of the sensor is greater than two orders of magnitude, and it is capable of detecting physiologically relevant levels of active thrombin down to 3 nM in buffered conditions. We expect these plasmon-mediated label-free sensors to open the window to a range of applications stretching from the diagnostic and characterization of bleeding disorders to fundamental proteolytic and pharmacological studies.
Sprache	Englisch
Erscheinungsdatum	2023-10-04
Erscheinungsland	United States
Dokumenttyp	Journal Article
ISSN	2771-9855
ISSN (online)	2771-9855
DOI	10.1021/acsaom.3c00226
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Contributions for the Validation of the European Portuguese Version of the Vascular Quality of Life-6 Questionnaire for Peripheral Artery Disease.

Oliveira, Rafaela / Pedras, Susana / Pimenta, Rui / Silva, Ivone

Acta medica portuguesa

2024 Band 37, Heft 6, Seite(n) 436–444

Abstract: Introduction: Peripheral arterial disease (PAD) is an occlusive atherosclerotic disease of the arteries of the extremities of the body that affects more than 230 million people worldwide. The most common symptom is intermittent claudication, described ... ...

Abstract	Introduction: Peripheral arterial disease (PAD) is an occlusive atherosclerotic disease of the arteries of the extremities of the body that affects more than 230 million people worldwide. The most common symptom is intermittent claudication, described as leg pain which occurs mainly while walking. The symptoms impair the ambulation and functional capacity of patients, leading to loss of mobility, disease deterioration, increased risk of other cardiovascular diseases, and lower quality of life (QoL). Therefore, the aim of this study was to perform a cross-cultural adaptation and validation of the VascuQol-6 questionnaire for the Portuguese population to obtain a quick, sensitive, and easy-to-use way to assess the QoL of Portuguese patients diagnosed with PAD. Methods: The Vascular Quality of Life-6 Questionnaire (VascuQoL-6) was adapted and translated into European Portuguese using standard validation methodology, including 115 patients with a mean age of 64.67 (7.23) years, with PAD with IC stable for more than three months; and ABI < 0.9 at rest. VascuQoL-6, SF-36, International Physical Activity Questionnaire (IPAQ), and the PAD Knowledge Questionnaire (PADKQ) were used. Reliability, construct validity analysis through convergent and discriminant validity, known-group validity, and responsiveness analysis were tested. Results: The Cronbach's alpha was 0.64 and the average inter-item correlation was 0.27, indicating acceptable internal consistency. VascuQoL-6 was positively associated with SF-36 Physical Component Summary and Mental Component Summary scores (r = 0.64, p < 0.01 and r = 0.42, p < 0.01, respectively). In turn, there was no significant correlation between VascuQoL-6 scores and the PADKQ or IPAQ. A statistically significant difference between groups according to IC severity [F(2.47) = 8.35, p < 0.001] was found. A paired samples t-test showed differences between VascuQol-6 scores before a walking program (M = 15.65, SD = 3.09), and after a walking program (M = 17.41, SD = 2.71), t(67) = 3.94, p ≤ 0.001. Conclusion: The VascuQoL-6 is a six-item instrument to assess the QoL associated with PAD with good psychometric properties, convergent and discriminant validity with SF-36, PADKQ and IPAQ. The instrument proved to have known group validity and responsiveness.
Mesh-Begriff(e)	Humans ; Quality of Life ; Peripheral Arterial Disease/diagnosis ; Male ; Female ; Middle Aged ; Portugal ; Translations ; Aged ; Surveys and Questionnaires/standards ; Reproducibility of Results ; Cultural Characteristics
Sprache	Englisch
Erscheinungsdatum	2024-06-03
Erscheinungsland	Portugal
Dokumenttyp	Journal Article ; Validation Study
ZDB-ID	603078-6
ISSN	1646-0758 ; 0870-399X
ISSN (online)	1646-0758
ISSN	0870-399X
DOI	10.20344/amp.20760
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Bioenergetic modelling of a marine top predator's responses to changes in prey structure.

Silva, Mariana P / Oliveira, Cláudia / Prieto, Rui / Silva, Mónica A / New, Leslie / Pérez-Jorge, Sergi

Ecology and evolution

2024 Band 14, Heft 3, Seite(n) e11135

Abstract: Determining how animals allocate energy, and how external factors influence this allocation, is crucial to understand species' life history requirements and response to disturbance. This response is driven in part by individuals' energy balance, prey ... ...

Abstract	Determining how animals allocate energy, and how external factors influence this allocation, is crucial to understand species' life history requirements and response to disturbance. This response is driven in part by individuals' energy balance, prey characteristics, foraging behaviour and energy required for essential functions. We developed a bioenergetic model to estimate minimum foraging success rate (FSR), that is, the lowest possible prey capture rate for individuals to obtain the minimum energy intake needed to meet daily metabolic requirements, for female sperm whale (
Sprache	Englisch
Erscheinungsdatum	2024-03-24
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	2635675-2
ISSN	2045-7758
ISSN	2045-7758
DOI	10.1002/ece3.11135
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Lessons from Four Decades of Systemic Amyloidosis with Renal Involvement.

Oliveira-Silva, Catarina / Marques, Nídia / Pinho, Ana / Poínhos, Rui / Bergantim, Rui / Nunes, Ana Teresa / Sampaio, Susana / Rodrigues-Pereira, Pedro / Silva, Roberto / Praça, Augusta / Frazão, João / Pestana, Manuel / Tavares, Isabel

Nephron

2022 Band 147, Heft 3-4, Seite(n) 158–169

Abstract: Background: Apart from ATTR amyloidosis, the epidemiology and outcomes of the most common subtypes of systemic amyloidosis in Portugal remain primarily unknown.: Methods: This retrospective cohort study evaluated patients with renal biopsy-proven ... ...

Abstract	Background: Apart from ATTR amyloidosis, the epidemiology and outcomes of the most common subtypes of systemic amyloidosis in Portugal remain primarily unknown. Methods: This retrospective cohort study evaluated patients with renal biopsy-proven amyloidosis, diagnosed from January 1978 to December 2019. Follow-up started at kidney disease presentation and ended at death or August 2020. Clinical presentation, survival, and prognostic factors were analysed. Results: Of 123 patients with amyloid nephropathy, 111 had definite amyloid typing and were analysed. AA amyloidosis was the most frequent type (56.1%) and was related mainly to chronic infection (47.8%) and chronic inflammatory arthritis (29.0%). AL amyloidosis was present in 25.2% of patients and hereditary forms in 6.5% (4.1% AFibE526V, 2.4% ATTRV30M). During follow-up, 73.9% of AA and 54.8% of AL patients progressed to end-stage renal disease, and 79.7% of AA and 77.4% of AL died; median overall survival was 66.0 (95% CI, 33.0-99.0) and 18.0 (95% CI, 9.3-26.7) months (p = 0.025), respectively. There were no significant differences in renal outcome and survival on dialysis between these two types. In multivariate analysis, cardiac involvement at presentation (HR 6.26 [95% CI, 2.89-13.56]) and estimated glomerular filtration rate <30 mL/min/1.73 m2 (HR 2.05 [95% CI, 1.06-3.99]) independently influenced AA and AL amyloidosis survival. Cardiac involvement at presentation was an independent predictor of death (HR 9.65 [95% CI, 2.91-31.95]) and early mortality in AL amyloidosis. Conclusions: In Portugal, AA amyloidosis and related chronic infections are still relevant. Regarding AL amyloidosis, the low incidence and advanced disease at presentation result from missed and erroneous diagnoses, leading to delayed referrals and poor outcomes in these patients.
Mesh-Begriff(e)	Humans ; Immunoglobulin Light-chain Amyloidosis ; Retrospective Studies ; Renal Dialysis ; Amyloidosis/epidemiology
Sprache	Englisch
Erscheinungsdatum	2022-09-12
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	207121-6
ISSN	2235-3186 ; 1423-0186 ; 1660-8151 ; 0028-2766
ISSN (online)	2235-3186 ; 1423-0186
ISSN	1660-8151 ; 0028-2766
DOI	10.1159/000525675
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Exploring the Bioactive Potential of

Oliveira, Rui S / Preto, Marco / Santos, Germana / Silva, Ana Margarida / Vasconcelos, Vitor / Martins, Rosário

Microorganisms

2024 Band 12, Heft 3

Abstract: Addressing pressing health concerns, modern medical research seeks to identify new antimicrobials to combat drug resistance, novel molecules for cancer treatment, and antioxidants for inflammation-related diseases. ...

Abstract	Addressing pressing health concerns, modern medical research seeks to identify new antimicrobials to combat drug resistance, novel molecules for cancer treatment, and antioxidants for inflammation-related diseases.
Sprache	Englisch
Erscheinungsdatum	2024-02-23
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Review
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms12030450
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Organisational culture and balanced scorecard

Cidália Oliveira / Margarida Rodrigues / Rui Silva / Mário Franco

Management : Journal of Contemporary Management Issues, Vol 28, Iss 2, Pp 133-

An empirical study in Portugal

2023 Band 149

Abstract: This study aims to identify and characterize the culture of the largest exporters without the Balanced Scorecard (BSC) and with the BSC implemented. In addition, it confirms whether there are different characteristics in the type of organizational ... ...

Abstract	This study aims to identify and characterize the culture of the largest exporters without the Balanced Scorecard (BSC) and with the BSC implemented. In addition, it confirms whether there are different characteristics in the type of organizational culture of the largest exporters without the BSC and with the BSC. To achieve this objective, data were collected through questionnaires sent to the 250 largest exporters in Portugal. Multivariate statistical techniques were used to validate the research hypotheses. This research shows that the Adhocracy (turbulent management) culture type prevails in organizations without BSC, while the Market (productivity) culture type prevails in organizations with BSC. The study is based on the characterization of the culture type of the organizations. This characterization is significant because organizational culture shapes and differentiates organizations’ actions, goal definitions, and strategic objectives, which can affect organizational performance. Although recent literature has addressed organizational culture and performance monitoring in isolation, not many studies have been found that link the topics of organizational culture, BSC, and performance.
Schlagwörter	Balanced Scorecard ; organizational culture ; performance ; major Portuguese exporters ; Economic growth ; development ; planning ; HD72-88 ; Economics as a science ; HB71-74
Thema/Rubrik (Code)	650
Sprache	Englisch
Erscheinungsdatum	2023-01-01T00:00:00Z
Verlag	University of Split, Faculty of Economics
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel: A review of machine learning methods for cancer characterization from microbiome data.

Teixeira, Marco / Silva, Francisco / Ferreira, Rui M / Pereira, Tania / Figueiredo, Ceu / Oliveira, Hélder P

NPJ precision oncology

2024 Band 8, Heft 1, Seite(n) 123

Abstract: Recent studies have shown that the microbiome can impact cancer development, progression, and response to therapies suggesting microbiome-based approaches for cancer characterization. As cancer-related signatures are complex and implicate many taxa, ... ...

Abstract	Recent studies have shown that the microbiome can impact cancer development, progression, and response to therapies suggesting microbiome-based approaches for cancer characterization. As cancer-related signatures are complex and implicate many taxa, their discovery often requires Machine Learning approaches. This review discusses Machine Learning methods for cancer characterization from microbiome data. It focuses on the implications of choices undertaken during sample collection, feature selection and pre-processing. It also discusses ML model selection, guiding how to choose an ML model, and model validation. Finally, it enumerates current limitations and how these may be surpassed. Proposed methods, often based on Random Forests, show promising results, however insufficient for widespread clinical usage. Studies often report conflicting results mainly due to ML models with poor generalizability. We expect that evaluating models with expanded, hold-out datasets, removing technical artifacts, exploring representations of the microbiome other than taxonomical profiles, leveraging advances in deep learning, and developing ML models better adapted to the characteristics of microbiome data will improve the performance and generalizability of models and enable their usage in the clinic.
Sprache	Englisch
Erscheinungsdatum	2024-05-30
Erscheinungsland	England
Dokumenttyp	Journal Article ; Review
ISSN	2397-768X
ISSN	2397-768X
DOI	10.1038/s41698-024-00617-7
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Neurological Spectrum of Epstein-Barr Virus Infection: A Rare Clinical Case.

Gomes, Dora / André, Rui / Oliveira, Catarina / Camões, Sofia / Silva, Catarina R / Mendes, Miguel L

Cureus

2024 Band 16, Heft 1, Seite(n) e53302

Abstract: The Epstein-Barr virus (EBV) is a DNA virus that has been infecting humans since ancient times, capable of causing a wide range of pathologies and affecting approximately 90% of the population. A 61-year-old male with no significant medical history ... ...

Abstract	The Epstein-Barr virus (EBV) is a DNA virus that has been infecting humans since ancient times, capable of causing a wide range of pathologies and affecting approximately 90% of the population. A 61-year-old male with no significant medical history presented with a 5-day history of imbalance and difficulty walking. Neurological examination revealed specific findings, including absent reflexes, bilateral asynergy, and gait abnormalities. Contrasting with Guillain-Barré Syndrome, lumbar puncture suggested a central nervous system infection. Serological testing confirmed Epstein-Barr virus (EBV) positivity, and intravenous immunoglobulin led to significant improvement. Electromyogram results suggested inflammatory/ipnfectious polyradiculopathy. Repeat EBV serology, showing strongly positive IgG and negative IgM, confirmed the diagnosis of Polyradiculoneuropathy secondary to EBV. This case underscores the rare neurological complications of EBV and the importance of considering viral infections in such presentations.
Sprache	Englisch
Erscheinungsdatum	2024-01-31
Erscheinungsland	United States
Dokumenttyp	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.53302
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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