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  1. Artikel ; Online: The mud volcanoes at Santa Barbara and Aragona (Sicily, Italy)

    A. Gattuso / F. Italiano / G. Capasso / A. D'Alessandro / F. Grassa / A. F. Pisciotta / D. Romano

    Natural Hazards and Earth System Sciences, Vol 21, Pp 3407-

    a contribution to risk assessment

    2021  Band 3419

    Abstract: The Santa Barbara and Aragona areas are affected by mud volcanism (MV) phenomena, consisting ... paroxysm surfaces of 0.12 and 0.20 km 2 for Santa Barbara and Aragona respectively were defined ... in Santa Barbara. From preliminary results, both seismic events and ambient noise showed a frequency of 5 ...

    Abstract The Santa Barbara and Aragona areas are affected by mud volcanism (MV) phenomena, consisting of continuous or intermittent emission of mud, water, and gases. This activity could be interrupted by paroxysmal events, with an eruptive column composed mainly of clay material, water, and gases. They are the most hazardous phenomena, and today it is impossible to define the potential parameters for modelling the phenomenon. In 2017, two digital surface models (DSMs) were performed by drone in both areas, thus allowing the mapping of the emission zones and the covered areas by the previous events. Detailed information about past paroxysms was obtained from historical sources, and, with the analysis of the 2017 DSMs, a preliminary hazard assessment was carried out for the first time at two sites. Two potentially hazardous paroxysm surfaces of 0.12 and 0.20 km 2 for Santa Barbara and Aragona respectively were defined. In May 2020, at Aragona, a new paroxysm covered a surface of 8721 m 2 . After this, a new detailed DSM was collected with the aim to make a comparison with the 2017 one. Since 2017, a seismic station was installed in Santa Barbara. From preliminary results, both seismic events and ambient noise showed a frequency of 5–10 Hz.
    Schlagwörter Environmental technology. Sanitary engineering ; TD1-1066 ; Geography. Anthropology. Recreation ; G ; Environmental sciences ; GE1-350 ; Geology ; QE1-996.5
    Thema/Rubrik (Code) 333
    Sprache Englisch
    Erscheinungsdatum 2021-11-01T00:00:00Z
    Verlag Copernicus Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Buch ; Online: IBD Management - Novel Targets and Therapeutic Perspectives

    Antonioli, Luca / Romano, Barbara / Blandizzi, Corrado / Fornai, Matteo

    2020  

    Schlagwörter Science: general issues ; Pharmacology ; IBD ; immune cells ; novel therapeutic agents ; inflammatory resolution ; cytokines
    Umfang 1 electronic resource (140 pages)
    Verlag Frontiers Media SA
    Dokumenttyp Buch ; Online
    Anmerkung English ; Open Access
    HBZ-ID HT021230172
    ISBN 9782889637713 ; 2889637719
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  3. Artikel ; Online: Urbanismo proempresarial y viviendas desocupadas en el área metropolitana de Buenos Aires

    Bárbara Teresa Romano

    Boletín de Estudios Geográficos, Iss

    el caso de la ciudad de Lomas de Zamora

    2021  Band 115

    Abstract: El proceso de recuperación económica que se vivenció luego de la crisis económica, social y política del año 2001 en la Argentina, representó una oportunidad, fundamentalmente, para el sector de la construcción y de los negocios inmobiliarios. Las ... ...

    Abstract El proceso de recuperación económica que se vivenció luego de la crisis económica, social y política del año 2001 en la Argentina, representó una oportunidad, fundamentalmente, para el sector de la construcción y de los negocios inmobiliarios. Las inversiones de los promotores inmobiliarios, amparados por los mismos gobiernos locales, se concentraron no solamente en los tradicionales barrios de la Ciudad Autónoma de Buenos Aires, sino también en zonas poco exploradas por el urbanismo proempresarial: las localidades cabeceras de los partidos del Área Metropolitana de Buenos Aires (AMBA). Una de ellas es Lomas de Zamora, que se ubica en el corredor sur del aglomerado, y ha experimentado un reciente proceso de verticalización que ha contribuido a la expansión de las viviendas desocupadas. En esta presentación, nos proponemos analizar la cantidad y distribución de viviendas desocupadas, a través de la información presente en los tres últimos censos nacionales de población, hogares y viviendas (INDEC, 1991 – 2001- 2010), en contraposición al crecimiento de la población residencial que parece estancado; con un enfoque que pretende interpretar las características que están por detrás del fenómeno (¿o estrategia inmobiliaria?) de las viviendas desocupadas.
    Schlagwörter vivienda desocupada ; alquiler ; financiarización de la vivienda ; Lomas de Zamora ; Geography (General) ; G1-922
    Sprache Englisch
    Erscheinungsdatum 2021-07-01T00:00:00Z
    Verlag Instituto de Geografía, Facultad de Filosofía y Letras, Universidad Nacional de Cuyo
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Expansão residencial e o aumento de inquilinato no centro da cidade de Lomas de Zamora, Buenos Aires. Argentina.

    Bárbara Teresa Romano

    Confins, Vol

    2020  Band 44

    Abstract: The cities in the metropolitan region of Buenos Aires have been the target of an important increase in real estate activity in the period after the 2001 crisis. However, the increase in the residential offer has not translated into possibilities of ... ...

    Abstract The cities in the metropolitan region of Buenos Aires have been the target of an important increase in real estate activity in the period after the 2001 crisis. However, the increase in the residential offer has not translated into possibilities of access to own housing, as the number of tenants has increased. In this work, the objective is to analyze the rental process in the city of Lomas de Zamora, with the increase in the number of buildings and the expansion of commercial stores that determined the configuration of an area dubbed by the real estate companies as “Las Lomitas”. In this sense, the research aims to analyze the interference of State policies and also of the market as agents that promote lease in the center of Lomas de Zamora.
    Schlagwörter Tenancy ; verticalization ; urban renewal ; Lomas de Zamora ; Geography. Anthropology. Recreation ; G
    Sprache Englisch
    Erscheinungsdatum 2020-03-01T00:00:00Z
    Verlag Confins
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Percutaneous management of iatrogenic Gerbode defect: a creative solution for a transseptal complication.

    Bellini, Barbara / Beneduce, Alessandro / Romano, Vittorio / Ancona, Francesco / Montorfano, Matteo

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2023  Band 24, Heft 4, Seite(n) 264–265

    Mesh-Begriff(e) Humans ; Heart Septal Defects, Ventricular/etiology ; Cardiac Catheterization/adverse effects ; Iatrogenic Disease
    Sprache Englisch
    Erscheinungsdatum 2023-01-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0000000000001434
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Malignant Peritoneal Mesothelioma: A Case Report.

    Sousa, Bárbara / Silva, Joana / Monteiro, Nereida / Romano, Miguel / Araújo, Elsa

    Cureus

    2023  Band 15, Heft 8, Seite(n) e42902

    Abstract: Malignant peritoneal mesothelioma (MPM) is a rare tumor of the serous membranes of the peritoneum and has been linked to exposure to asbestos and other risk factors. The clinical manifestations are vague, with a wide clinical spectrum, predominantly ... ...

    Abstract Malignant peritoneal mesothelioma (MPM) is a rare tumor of the serous membranes of the peritoneum and has been linked to exposure to asbestos and other risk factors. The clinical manifestations are vague, with a wide clinical spectrum, predominantly related to the abdominal involvement of the disease. Localized mesothelioma is an uncommon manifestation of the disease. Common symptoms include abdominal pain or abdominal distention, nausea, anorexia, and weight loss. Rarely, patients present with paraneoplastic syndrome. Due to the nonspecific symptoms, many patients already have advanced disease at the time of diagnosis. The authors report a case of a 75-year-old female patient who presented with symptoms of asthenia, anorexia, progressive paleness, and weight loss lasting five months. She reports later new-onset symptoms of diffuse abdominal pain and diarrhea associated with nausea. Laboratory tests showed anemia, mild leukocytosis, thrombocytosis, elevated C-reactive protein (CRP), and elevated liver enzymes. An abdominal and pelvic computed tomography (CT) scan revealed marked tissue thickening of an irregular and striated configuration of the leaflets and peritoneal reflections in an omental cake pattern, and a chest CT scan showed multiple bilateral pulmonary nodules, suggesting diffuse malignant disease. A CT-guided biopsy of a peritoneal implant was performed, establishing the diagnosis of malignant peritoneal mesothelioma. Due to rapid clinical deterioration, the patient did not receive any systemic treatment, surgery, or radiotherapy and was transitioned to comfort care. As in the presented case, most cases of MPM have diffuse peritoneal involvement at the time of diagnosis, although extra-abdominal involvement is very rare. This disease presentation is associated with high morbidity and mortality compared to cases of localized disease. There is no specific imaging diagnostic modality or valuable tumor markers for MPM. Although a CT scan remains important in the diagnostic approach, the changes found are not specific. Radiographically, MPM may present as mesenteric or parietal peritoneal nodules, visceral peritoneal thickening, ascites, or omental masses. Although these features may raise suspicion of MPM, a biopsy is necessary to confirm the diagnosis. Therefore, due to the rarity of this disease and its nonspecific signs or symptoms, MPM is difficult to diagnose, and the prognosis remains poor.
    Sprache Englisch
    Erscheinungsdatum 2023-08-03
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.42902
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Enhanced Stability of Oral Vitamin C Delivery: A Novel Large-Scale Method for Liposomes Production and Encapsulation through Dynamic High-Pressure Microfluidization.

    Romano, Eugenia / Palladino, Roberta / Cannavale, Mariagabriella / Lamparelli, Erwin Pavel / Maglione, Barbara

    Nanomaterials (Basel, Switzerland)

    2024  Band 14, Heft 6

    Abstract: In recent years, nanocarriers have been widely used as an effective solution for oral administration of pharmaceuticals. However, there is still an urgent need to speed up their translation to clinical practice. Cost-effective and industrially scalable ... ...

    Abstract In recent years, nanocarriers have been widely used as an effective solution for oral administration of pharmaceuticals. However, there is still an urgent need to speed up their translation to clinical practice. Cost-effective and industrially scalable methodologies are still needed. Herein, the production of vitamin C-loaded liposomes for nutraceutical purposes has been investigated and optimized by adopting a High-Pressure Homogenizer. Initially, the impact of process parameters on particles size, distributions, and morphology was explored. The findings document that the pressure and cycle manipulation allow for control over liposome size and polydispersity, reaching a maximum encapsulation efficiency exceeding 80%. This significantly improves the storage stability of vitamin C, as demonstrated by monitoring its antioxidant activity. Furthermore, the in vitro simulation of gastrointestinal digestion shows that liposomes could protect the active substance from damage and control its release in the gastrointestinal fluid. Thus, the whole nanodelivery system can contribute to enhancing vitamin C bioavailability. In conclusion, the results indicate that this innovative approach to producing vitamin C liposomes holds promise for clinical translation and industrial scale-up. Indeed, by utilizing food-grade materials and straightforward equipment, it is possible to produce stable and functional liposomes suitable for health products.
    Sprache Englisch
    Erscheinungsdatum 2024-03-14
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano14060516
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Technical Evaluation of a New Medical Device Based on Rigenase in the Treatment of Chronic Skin Lesions.

    Romano, Eugenia / Campagnuolo, Claudio / Palladino, Roberta / Schiavo, Giulia / Maglione, Barbara / Luceri, Cristina / Mennini, Natascia

    Bioengineering (Basel, Switzerland)

    2023  Band 10, Heft 9

    Abstract: Chronic wound is characterized by slow healing time, persistence, and abnormal healing progress. Therefore, serious complications can lead at worst to the tissue removal. In this scenario, there is an urgent need for an ideal dressing capable of high ... ...

    Abstract Chronic wound is characterized by slow healing time, persistence, and abnormal healing progress. Therefore, serious complications can lead at worst to the tissue removal. In this scenario, there is an urgent need for an ideal dressing capable of high absorbency, moisture retention and antimicrobial properties. Herein we investigate the technical properties of a novel advanced non-woven triple layer gauze imbibed with a cream containing Rigenase, an aqueous extract of
    Sprache Englisch
    Erscheinungsdatum 2023-08-29
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering10091022
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Topical Collection "Pharmacology of Medicinal Plants".

    Romano, Barbara / Lucariello, Giuseppe / Capasso, Raffaele

    Biomolecules

    2021  Band 11, Heft 1

    Abstract: The use of remedies based on medicinal plants continues to expand rapidly around the world, with many people now resorting to this type of product for the treatment and prevention of several pathologies [ ... ]. ...

    Abstract The use of remedies based on medicinal plants continues to expand rapidly around the world, with many people now resorting to this type of product for the treatment and prevention of several pathologies [...].
    Mesh-Begriff(e) Animals ; Cell Line, Tumor ; Humans ; Mice ; Pharmacology ; Phytochemicals/pharmacology ; Phytotherapy ; Plants, Medicinal/chemistry
    Chemische Substanzen Phytochemicals
    Sprache Englisch
    Erscheinungsdatum 2021-01-14
    Erscheinungsland Switzerland
    Dokumenttyp Editorial ; Introductory Journal Article
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom11010101
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  10. Artikel ; Online: Unveiling the genetic landscape of suspected congenital dyserythropoietic anemia type I: A retrospective cohort study of 36 patients.

    Marra, Roberta / Nostroso, Antonella / Rosato, Barbara Eleni / Esposito, Federica Maria / D'Onofrio, Vanessa / Iscaro, Anthony / Gambale, Antonella / Bruschi, Barbara / Coccia, Paola / Poloni, Antonella / Unal, Sule / Romano, Alberto / Iolascon, Achille / Andolfo, Immacolata / Russo, Roberta

    American journal of hematology

    2024  

    Abstract: Congenital Dyserythropoietic Anemia type I (CDA I) is a rare hereditary condition characterized by macrocytic/normocytic anemia, splenomegaly, iron overload, and distinct abnormalities during late erythropoiesis, particularly internuclear bridges between ...

    Abstract Congenital Dyserythropoietic Anemia type I (CDA I) is a rare hereditary condition characterized by macrocytic/normocytic anemia, splenomegaly, iron overload, and distinct abnormalities during late erythropoiesis, particularly internuclear bridges between erythroblasts. Diagnosis of CDA I remains challenging due to its rarity, clinical heterogeneity, and overlapping phenotype with other rare hereditary anemias. In this case series, we present 36 patients with suspected CDA I. A molecular diagnosis was successfully established in 89% of cases, identifying 16 patients with CDA I through the presence of 18 causative variants in the CDAN1 or CDIN1 genes. Transcriptomic analysis of CDIN1 variants revealed impaired erythroid differentiation and disruptions in transcription, cell proliferation, and histone regulation. Conversely, 16 individuals received a different diagnosis, primarily pyruvate kinase deficiency. Comparisons between CDA I and non-CDA I patients revealed no significant differences in erythroblast morphological features. However, hemoglobin levels and red blood cell count differed between the two groups, with non-CDA I subjects being more severely affected. Notably, most patients with severe anemia belonged to the non-CDA I group (82% non-CDA I vs. 18% CDA I), with a subsequent absolute prevalence of transfusion dependency among non-CDA I patients (100% vs. 41.7%). All patients exhibited reduced bone marrow responsiveness to anemia, with a more pronounced effect observed in non-CDA I patients. Erythropoietin levels were significantly higher in non-CDA I patients compared to CDA I patients. However, evaluations of erythroferrone, soluble transferrin receptor, and hepcidin revealed no significant differences in plasma concentration between the two groups.
    Sprache Englisch
    Erscheinungsdatum 2024-04-26
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.27350
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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