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  1. Article: Endocrowns: review.

    Sevimli, Gaye / Cengiz, Seda / Oruc, M Selcuk

    Journal of Istanbul University Faculty of Dentistry

    2015  Volume 49, Issue 2, Page(s) 57–63

    Abstract: The ideal restoration of endodontically treated teeth (ETT) has been widely and controversially discussed in the literature. Prevention of healthy dental structure is essential to help mechanical stabilization of tooth-restoration integrity, increase the ...

    Abstract The ideal restoration of endodontically treated teeth (ETT) has been widely and controversially discussed in the literature. Prevention of healthy dental structure is essential to help mechanical stabilization of tooth-restoration integrity, increase the amount of suitable surfaces for adhesion and thus positively affect the long-term success. ETT are affected by a higher risk of biomechanical failure than vital teeth. With the development of adhesive systems, the need for post-core restorations is also reduced. Especially for restoration of excessively damaged ETT, endocrowns have been used as an alternative to the conventional post-core and fixed partial dentures. Compared to conventional methods, good aesthetics, better mechanical performance, and less cost and clinic time are the advantages of endocrowns.
    Language English
    Publishing date 2015-04-29
    Publishing country Turkey
    Document type Journal Article ; Review
    ISSN 2149-2352
    ISSN 2149-2352
    DOI 10.17096/jiufd.71363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A novel niosome formulation for encapsulation of anthocyanins and modelling intestinal transport.

    Fidan-Yardimci, Melike / Akay, Seref / Sharifi, Fatemeh / Sevimli-Gur, Canan / Ongen, Gaye / Yesil-Celiktas, Ozlem

    Food chemistry

    2019  Volume 293, Page(s) 57–65

    Abstract: The bioavailability of drugs can be improved by regulating the structural properties, particularly lipoid systems, such as niosomes, can increase cellular uptake. Herein, we optimized double emulsion and niosomal formulations for encapsulating ... ...

    Abstract The bioavailability of drugs can be improved by regulating the structural properties, particularly lipoid systems, such as niosomes, can increase cellular uptake. Herein, we optimized double emulsion and niosomal formulations for encapsulating anthocyanin-rich black carrot extract. Nanoparticles obtained by selected formulation were characterized in terms of morphology, particle size, drug encapsulation efficiency, in vitro release and cytotoxicity. The optimum conditions for niosomal formulation were elicited as 30 mg of cholesterol, 150 mg of Tween 20 and feeding time of 1 min at a stirring rate of 900 rpm yielding the lowest average particle size of 130 nm. In vitro release data showed the majority of the encapsulated anthocyanins were released at the end of 10 h. A mathematical model was developed to estimate the absorption of anthocyanins released from niosomes and cytotoxicity was assessed against neuroblastoma. Overall, these findings suggest that niosomal vesicles might be suitable delivery systems for anthocyanins.
    MeSH term(s) Anthocyanins/chemistry ; Anthocyanins/metabolism ; Calorimetry, Differential Scanning ; Cell Line, Tumor ; Cell Survival/drug effects ; Cholesterol/chemistry ; Daucus carota/chemistry ; Daucus carota/metabolism ; Humans ; Liposomes/chemistry ; Liposomes/toxicity ; Models, Theoretical ; Nanoparticles/chemistry ; Particle Size ; Polysorbates/chemistry
    Chemical Substances Anthocyanins ; Liposomes ; Polysorbates ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2019-04-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2019.04.086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 3634: Show issues

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  3. Article: A novel niosome formulation for encapsulation of anthocyanins and modelling intestinal transport

    Fidan-Yardimci, Melike / Akay, Seref / Sharifi, Fatemeh / Sevimli-Gur, Canan / Ongen, Gaye / Yesil-Celiktas, Ozlem

    Food chemistry. 2019 Sept. 30, v. 293

    2019  

    Abstract: The bioavailability of drugs can be improved by regulating the structural properties, particularly lipoid systems, such as niosomes, can increase cellular uptake. Herein, we optimized double emulsion and niosomal formulations for encapsulating ... ...

    Abstract The bioavailability of drugs can be improved by regulating the structural properties, particularly lipoid systems, such as niosomes, can increase cellular uptake. Herein, we optimized double emulsion and niosomal formulations for encapsulating anthocyanin-rich black carrot extract. Nanoparticles obtained by selected formulation were characterized in terms of morphology, particle size, drug encapsulation efficiency, in vitro release and cytotoxicity. The optimum conditions for niosomal formulation were elicited as 30 mg of cholesterol, 150 mg of Tween 20 and feeding time of 1 min at a stirring rate of 900 rpm yielding the lowest average particle size of 130 nm. In vitro release data showed the majority of the encapsulated anthocyanins were released at the end of 10 h. A mathematical model was developed to estimate the absorption of anthocyanins released from niosomes and cytotoxicity was assessed against neuroblastoma. Overall, these findings suggest that niosomal vesicles might be suitable delivery systems for anthocyanins.
    Keywords absorption ; anthocyanins ; bioavailability ; carrots ; cholesterol ; cytotoxicity ; drugs ; emulsions ; encapsulation ; intestines ; mathematical models ; mixing ; nanoparticles ; niosomes ; particle size ; polysorbates
    Language English
    Dates of publication 2019-0930
    Size p. 57-65.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2019.04.086
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 3634: Show issues

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  4. Article ; Online: Color Stability and Surface Roughness of a Laboratory-Processed Composite Resin as a Function of Mouthrinse.

    Cengiz, Seda / Yüzbaşioğlu, Emir / Cengiz, M Inanç / Velioğlu, Neslin / Sevimli, Gaye

    Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.

    2015  Volume 27, Issue 5, Page(s) 314–321

    Abstract: Statement of the problem: Mouthrinses can cause discoloration on indirect resin composites.: Purpose of the study: The purpose of the study was to investigate the effect of different mouthrinses on the color changes and surface roughness of a ... ...

    Abstract Statement of the problem: Mouthrinses can cause discoloration on indirect resin composites.
    Purpose of the study: The purpose of the study was to investigate the effect of different mouthrinses on the color changes and surface roughness of a laboratory-processed composite.
    Methods and materials: Fifty discs were made using GC Gradia/GC indirect composites and divided into five groups which immersed in artificial saliva and four different types of mouthrinses. The samples were immersed daily for 14 days in 20 mL of the solutions for 2 minutes twice a day (with a 12-hour interval between exposures). Measurements were carried out at four different times: 1 hour after sample preparation (t0 ), 1 day (t1 ), 7 days (t2 ), and 14 days (t3 ) after the first immersion in the solutions. The color before and after immersion was measured according to Comission Internationale de L'Eclairage (CIE L*, a*, b*) System and ΔL*, Δa*, Δb*, and ΔE* values were calculated. The surface roughness Ra (μm) of the specimens was evaluated using a profilometer.
    Results: There were significant differences between the groups at all time representing ΔE values (p < 0.001). At (t1 ) time representing ΔRa value, there were significant differences between the groups (p < 0.05). At (t2, t3 ) time representing ΔRa values, there were significant differences between the groups (p < 0.001). Pharmol Zn immersed specimens showed ΔE values between 1.04 and 3.67.
    Conclusions: The result of this study indicated that the mouthrinses affected the color stability of indirect composites.
    Clinical significance: Based on the results of this study, patients with resin composite restorations should be warned by the dentists about the discoloration of the restorations and the time period of the mouthrinse that will be used.
    MeSH term(s) Color ; Composite Resins ; Humans ; Mouthwashes ; Surface Properties
    Chemical Substances Composite Resins ; Mouthwashes
    Language English
    Publishing date 2015-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2043146-6
    ISSN 1708-8240 ; 1496-4155
    ISSN (online) 1708-8240
    ISSN 1496-4155
    DOI 10.1111/jerd.12167
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3314: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: ENDOCROWNS: REVIEW

    Sevimli, Gaye / Cengiz, Seda / Bülent Ecevit Üniversitesi Diş Hekimliği Fakültesi Protetik Diş Tedavisi AD / Oruç, Selçuk

    Journal of Istanbul University Faculty of Dentistry; Vol 49, No 2 (2015); 57-63

    Abstract: The ideal restoration of endodontically treatedteeth (ETT) has been widely and controversiallydiscussed in the literature. Prevention of healthydental structure is essential to help mechanicalstabilization of tooth-restoration integrity, increasethe ... ...

    Abstract The ideal restoration of endodontically treatedteeth (ETT) has been widely and controversiallydiscussed in the literature. Prevention of healthydental structure is essential to help mechanicalstabilization of tooth-restoration integrity, increasethe amount of suitable surfaces for adhesion andthus positively affect the long-term success. ETT areaffected by a higher risk of biomechanical failure thanvital teeth. With the development of adhesive systems,the need for post-core restorations is also reduced.Especially for restoration of excessively damagedETT, endocrowns have been used as an alternative tothe conventional post-core and fixed partial dentures.Compared to conventional methods, good aesthetics,better mechanical performance, and less cost andclinic time are the advantages of endocrowns.
    Language English
    Document type Article
    ISSN 2149-4592
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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