LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 10 von insgesamt 144

Suchoptionen

  1. Artikel: Understanding the Mechanism of Antimicrobial Resistance and Pathogenesis of

    Khan, Maryam / Shamim, Saba

    Microorganisms

    2022  Band 10, Heft 10

    Abstract: Salmonella ... ...

    Abstract Salmonella enterica
    Sprache Englisch
    Erscheinungsdatum 2022-10-11
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms10102006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  2. Artikel: Anisi Stellati Fructus

    Khan, Maryam / Shamim, Saba

    Evidence-based complementary and alternative medicine : eCAM

    2022  Band 2022, Seite(n) 4071489

    Abstract: Anisi stellati ... ...

    Abstract Anisi stellati fructus
    Sprache Englisch
    Erscheinungsdatum 2022-05-09
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2022/4071489
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  3. Artikel ; Online: Anisi Stellati Fructus, a Significant Traditional Chinese Medicine (TCM) Herb and Its Bioactivity against Gastric Cancer

    Maryam Khan / Saba Shamim

    Evidence-Based Complementary and Alternative Medicine, Vol

    2022  Band 2022

    Abstract: Anisi stellati fructus (ASF) is the fruit of Illicium verum Hook F. (Chinese star anise), which is native to many countries, and is a significant Chinese medicinal herb. Gastric cancer (GC) is one of the major fatal types of cancers with multiple stages ... ...

    Abstract Anisi stellati fructus (ASF) is the fruit of Illicium verum Hook F. (Chinese star anise), which is native to many countries, and is a significant Chinese medicinal herb. Gastric cancer (GC) is one of the major fatal types of cancers with multiple stages and a poor prognosis. The present review aims to discuss the bioactive properties of ASF and its phytocompounds against GC, with a particular insight into the molecular mechanisms and signaling pathways involved in its anti-GC mechanism. Furthermore, it highlights the potential mechanism of action of major phytocompounds of ASF against GC. Clinical studies (in vitro and in vivo) regarding the action of ASF and its major bioactive compounds such as quercetin, luteolin, kaempferol, d-limonene, and honokiol against GC were reviewed. For this review, search of literature was performed in Science, PubMed, Google Scholar, Web of Science, and Scopus related to ASF and its phytocompounds, from which only relevant studies were chosen. Major bioactive compounds of ASF and their extracts have proven to be effective against GC due to the mechanistic action of these compounds involving signaling pathways that target cancer cell apoptosis, proliferation, and tumor metastasis in GC cells. Existing reports of these compounds and their combinatory effects with other modern anticancer agents have also been reviewed. From its traditional use to its role as an anticancer agent, ASF and its bioactive phytocompounds have been observed to be effective in modern research, specifically against GC. However, further studies are required for the identification of molecular targets and pharmacokinetic potential and for the formulation of anti-GC drugs.
    Schlagwörter Other systems of medicine ; RZ201-999
    Thema/Rubrik (Code) 500
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag Hindawi Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Zusatzmaterialien

    Kategorien

  4. Artikel ; Online: Correction: Encyclopaedic Review of Glipizide Pre-clinical and Clinical Status.

    Mohammed, Saad / Mahmood, Tarique / Shamim, Arshiya / Ahsan, Farogh / Shariq, Mohammad / Parveen, Saba / Waseem, Rufaida / Singh, Aditya

    Drug research

    2024  Band 74, Heft 3, Seite(n) e2

    Sprache Englisch
    Erscheinungsdatum 2024-05-15
    Erscheinungsland Germany
    Dokumenttyp Journal Article ; Published Erratum
    ZDB-ID 2703847-6
    ISSN 2194-9387 ; 2194-9379
    ISSN (online) 2194-9387
    ISSN 2194-9379
    DOI 10.1055/a-2321-8886
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  5. Artikel: [Titelangabe fehlt]

    Mohammed, Saad / Mahmood, Tarique / Shamim, Arshiya / Ahsan, Farogh / Shariq, Mohammad / Parveen, Saba / Waseem, Rufaida / Singh, Aditya

    Drug Research

    2024  Band 74, Heft 03, Seite(n) e2–e2

    Sprache Englisch
    Erscheinungsdatum 2024-03-01
    Verlag Georg Thieme Verlag KG
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel
    ZDB-ID 2703847-6
    ISSN 2194-9387 ; 2194-9379
    ISSN (online) 2194-9387
    ISSN 2194-9379
    DOI 10.1055/a-2321-8886
    Datenquelle Thieme Verlag

    Zusatzmaterialien

    Kategorien

  6. Artikel: Investigation of the Antibacterial, Anti-Biofilm, and Antioxidative Effect of

    Jalil, Varda / Khan, Maryam / Haider, Syed Zeeshan / Shamim, Saba

    Microorganisms

    2022  Band 10, Heft 12

    Abstract: Among oral diseases, dental caries is one of the most frequent to affect human health. The current research work aimed to ascertain the antibacterial, anti-biofilm, and antioxidative potential ... ...

    Abstract Among oral diseases, dental caries is one of the most frequent to affect human health. The current research work aimed to ascertain the antibacterial, anti-biofilm, and antioxidative potential of
    Sprache Englisch
    Erscheinungsdatum 2022-12-15
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms10122485
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  7. Artikel: Corrigendum: Zinc essentiality, toxicity, and its bacterial bioremediation: A comprehensive insight.

    Hussain, Sarfraz / Khan, Maryam / Sheikh, Taha Majid Mahmood / Mumtaz, Muhammad Zahid / Chohan, Talha Ali / Shamim, Saba / Liu, Yuhong

    Frontiers in microbiology

    2023  Band 13, Seite(n) 1133733

    Abstract: This corrects the article DOI: 10.3389/fmicb.2022.900740.]. ...

    Abstract [This corrects the article DOI: 10.3389/fmicb.2022.900740.].
    Sprache Englisch
    Erscheinungsdatum 2023-01-17
    Erscheinungsland Switzerland
    Dokumenttyp Published Erratum
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.1133733
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  8. Artikel ; Online: Encyclopaedic Review of Glipizide Pre-clinical and Clinical Status.

    Mohammed, Saad / Mahmood, Tarique / Shamim, Arshiya / Ahsan, Farogh / Shariq, Mohammad / Parveen, Saba / Waseem, Rufaida / Singh, Aditya

    Drug research

    2024  Band 74, Heft 3, Seite(n) 123–132

    Abstract: Glipizide is an oral glucose-lowering medication that is beneficial for the treatment of type 2 diabetes. This study compiles exhaustively all accessible information on glipizide, from preclinical to clinical studies. Glipizide may be used in concert ... ...

    Abstract Glipizide is an oral glucose-lowering medication that is beneficial for the treatment of type 2 diabetes. This study compiles exhaustively all accessible information on glipizide, from preclinical to clinical studies. Glipizide may be used in concert with TRAIL to treat cancer cells; in vitro studies have shown that it suppresses angiogenesis and vasculogenesis while shielding cells from glycation-induced damage. Anticonvulsant effects and modifications in the pharmacokinetics of other medications, such as Divalproex Sodium, were seen in glipizide in vivo experiments. Propranolol amplifies glipizide's hypoglycemic effect briefly in normal animals but consistently enhances it in diabetic ones. In the treatment of cancer and neurodegenerative poly(Q) illnesses, glipizide has demonstrated to offer potential therapeutic advantages. It is ineffective in preventing DENA-induced liver cancer and may cause DNA damage over time. The way glipizide interacts with genetic variants may increase the risk of hypoglycemia. Combining Syzygium cumini and ARBE to glipizide may enhance glycemic and lipid control in type 2 diabetes. Individuals with coronary artery disease who take glipizide or glyburide have an increased risk of death. The risk of muscular responses and acute pancreatitis is minimal when glipizide and dulaglutide are combined. In conclusion, glipizide has shown promising therapeutic efficacy across a variety of disorders.
    Mesh-Begriff(e) Humans ; Glipizide/adverse effects ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/chemically induced ; Acute Disease ; Blood Glucose ; Pancreatitis/chemically induced ; Pancreatitis/drug therapy
    Chemische Substanzen Glipizide (X7WDT95N5C) ; Blood Glucose
    Sprache Englisch
    Erscheinungsdatum 2024-02-26
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 2703847-6
    ISSN 2194-9387 ; 2194-9379
    ISSN (online) 2194-9387
    ISSN 2194-9379
    DOI 10.1055/a-2237-8566
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  9. Artikel ; Online: Continuing professional development for pharmacists in three countries with developing health systems.

    Shamim, Saba / Rasheed, Huma / Babar, Zaheer-Ud-Din

    Currents in pharmacy teaching & learning

    2021  Band 13, Heft 5, Seite(n) 471–478

    Abstract: Introduction: The role of pharmacists in healthcare is undergoing transformation throughout the world. The continuing professional development (CPD) model has motivated pharmacists in developed countries to adopt lifelong learning. This is vital to ... ...

    Abstract Introduction: The role of pharmacists in healthcare is undergoing transformation throughout the world. The continuing professional development (CPD) model has motivated pharmacists in developed countries to adopt lifelong learning. This is vital to improve competence and to optimize patient care. This study aimed to explore the existence and understanding of CPD in Ghana, Pakistan, and Trinidad and Tobago, the barriers faced in development of a CPD model, and probable policies needed to build/improve such a model.
    Methods: Audiotaped qualitative in-depth interviews were conducted, transcribed, and coded with pharmacy stakeholders, including academics, community pharmacists, and regulatory professionals. A thematic analysis of the transcribed data led to the extraction of the main themes.
    Results: The findings showed a process of establishment of CPD for pharmacists in Ghana, whereas in Pakistan, Trinidad, and Tobago there was no CPD model.
    Conclusions: These findings indicate the need for a realistic, relevant, and mandatory program of CPD in these countries.
    Mesh-Begriff(e) Education, Pharmacy, Continuing ; Humans ; Learning ; Pharmaceutical Services ; Pharmacies ; Pharmacists
    Sprache Englisch
    Erscheinungsdatum 2021-02-03
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2515217-8
    ISSN 1877-1300 ; 1877-1297
    ISSN (online) 1877-1300
    ISSN 1877-1297
    DOI 10.1016/j.cptl.2021.01.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  10. Artikel: Unraveling the Underlying Heavy Metal Detoxification Mechanisms of

    Alotaibi, Badriyah Shadid / Khan, Maryam / Shamim, Saba

    Microorganisms

    2021  Band 9, Heft 8

    Abstract: The rise of anthropogenic activities has resulted in the increasing release of various contaminants into the environment, jeopardizing fragile ecosystems in the process. Heavy metals are one of the major pollutants that contribute to the escalating ... ...

    Abstract The rise of anthropogenic activities has resulted in the increasing release of various contaminants into the environment, jeopardizing fragile ecosystems in the process. Heavy metals are one of the major pollutants that contribute to the escalating problem of environmental pollution, being primarily introduced in sensitive ecological habitats through industrial effluents, wastewater, as well as sewage of various industries. Where heavy metals like zinc, copper, manganese, and nickel serve key roles in regulating different biological processes in living systems, many heavy metals can be toxic even at low concentrations, such as mercury, arsenic, cadmium, chromium, and lead, and can accumulate in intricate food chains resulting in health concerns. Over the years, many physical and chemical methods of heavy metal removal have essentially been investigated, but their disadvantages like the generation of chemical waste, complex downstream processing, and the uneconomical cost of both methods, have rendered them inefficient,. Since then, microbial bioremediation, particularly the use of bacteria, has gained attention due to the feasibility and efficiency of using them in removing heavy metals from contaminated environments. Bacteria have several methods of processing heavy metals through general resistance mechanisms, biosorption, adsorption, and efflux mechanisms.
    Sprache Englisch
    Erscheinungsdatum 2021-07-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms9081628
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang