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Artikel ; Online: World Psychiatric Association position statement on mental health and the death penalty.

Misra, Maitreyi / Sinha, Namrata / Pathare, Soumitra / Gill, Neeraj / Javed, Afzal

The lancet. Psychiatry

2024 Band 11, Heft 4, Seite(n) 239–241

Mesh-Begriff(e)	Humans ; Mental Health ; Capital Punishment ; Forensic Psychiatry
Sprache	Englisch
Erscheinungsdatum	2024-02-05
Erscheinungsland	England
Dokumenttyp	Journal Article
ISSN	2215-0374
ISSN (online)	2215-0374
DOI	10.1016/S2215-0366(23)00434-0
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Longitudinal NMR Based Serum Metabolomics to Track the Potential Serum Biomarkers of Septic Shock.

Pandey, Swarnima / Azim, Afzal / Sinha, Neeraj

Nanotheranostics

2023 Band 7, Heft 2, Seite(n) 142–151

Abstract: Background: ...

Abstract	Background:
Mesh-Begriff(e)	Humans ; Shock, Septic/diagnosis ; Shock, Septic/metabolism ; Prospective Studies ; Biomarkers/metabolism ; Metabolomics ; Magnetic Resonance Spectroscopy
Chemische Substanzen	Biomarkers
Sprache	Englisch
Erscheinungsdatum	2023-01-01
Erscheinungsland	Australia
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2206-7418
ISSN (online)	2206-7418
DOI	10.7150/ntno.79394
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Lung Transplantation in Patients with Cystic Fibrosis: A Complex Task, A Changing Target.

Loebe, Matthias / Deuse, Tobias / Sinha, Neeraj / Koster, Andreas / Erdoes, Gabor

Journal of cardiothoracic and vascular anesthesia

2023 Band 38, Heft 3, Seite(n) 635–637

Mesh-Begriff(e)	Humans ; Cystic Fibrosis/surgery ; Lung Transplantation ; Postoperative Complications
Sprache	Englisch
Erscheinungsdatum	2023-12-21
Erscheinungsland	United States
Dokumenttyp	Editorial
ZDB-ID	1067317-9
ISSN	1532-8422 ; 1053-0770
ISSN (online)	1532-8422
ISSN	1053-0770
DOI	10.1053/j.jvca.2023.12.020
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Lung transplant in chronic HIV infection.

Yarlagadda, Keerthi / Werne, Rachel / Sinha, Neeraj

BMJ case reports

2023 Band 16, Heft 11

Abstract: Lung transplantation is the treatment of choice for many end-stage chronic lung conditions. Chronic Human Immunodeficiency Virus (HIV) infection is considered a relative contraindication for lung transplantation. In the era of Highly Active ... ...

Abstract	Lung transplantation is the treatment of choice for many end-stage chronic lung conditions. Chronic Human Immunodeficiency Virus (HIV) infection is considered a relative contraindication for lung transplantation. In the era of Highly Active Antiretroviral Therapy (HAART), there has been an increase in the number of HIV-positive patients living with chronic lung conditions. In this paper, we aim to summarise the available literature in the field of lung transplantation in HIV-positive patients. We also present our experience of an HIV-positive woman who underwent lung transplantation for chronic interstitial lung disease from an HIV-negative donor.Careful candidate selection, along with management focused on closer monitoring, may result in favourable outcomes, including improved longevity among HIV-positive patients with chronic lung disease.
Mesh-Begriff(e)	Female ; Humans ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV Seropositivity ; Lung Transplantation ; Kidney Transplantation ; Antiretroviral Therapy, Highly Active
Sprache	Englisch
Erscheinungsdatum	2023-11-14
Erscheinungsland	England
Dokumenttyp	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2022-253855
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: 1

Dwivedi, Navneet / Siddiqui, Mohd Adnan / Srivastava, Seema / Sinha, Neeraj

Magnetic resonance in chemistry : MRC

2023 Band 61, Heft 7, Seite(n) 397–406

Abstract: Bone is a living tissue made up of organic proteins, inorganic minerals, and water. The organic component of bone (mainly made up of Type-I collagen) provides flexibility and tensile strength. Solid-state nuclear magnetic resonance (ssNMR) is one of the ... ...

Abstract	Bone is a living tissue made up of organic proteins, inorganic minerals, and water. The organic component of bone (mainly made up of Type-I collagen) provides flexibility and tensile strength. Solid-state nuclear magnetic resonance (ssNMR) is one of the few techniques that can provide atomic-level structural insights of such biomaterials in their native state. In the present article, we employed the variable contact time cross-polarization (
Mesh-Begriff(e)	Kinetics ; Bone and Bones ; Extracellular Matrix/metabolism ; Collagen/chemistry ; Water/chemistry
Chemische Substanzen	Collagen (9007-34-5) ; Water (059QF0KO0R)
Sprache	Englisch
Erscheinungsdatum	2023-03-29
Erscheinungsland	England
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1475029-6
ISSN	1097-458X ; 0749-1581
ISSN (online)	1097-458X
ISSN	0749-1581
DOI	10.1002/mrc.5347
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: A pandemic of acute respiratory distress syndrome-role of lung transplant in coronavirus disease-2019-associated respiratory failure.

Manickavel, Suresh / Sinha, Neeraj

Indian journal of thoracic and cardiovascular surgery

2021 Band 37, Heft Suppl 3, Seite(n) 359–365

Abstract: Lung transplantation may be appropriate, and may offer benefit only to a carefully selected subset of morbidly ill patients afflicted by coronavirus disease-2019. Identifying the appropriate recipient for the allocation of scarce resources, by safely ... ...

Abstract	Lung transplantation may be appropriate, and may offer benefit only to a carefully selected subset of morbidly ill patients afflicted by coronavirus disease-2019. Identifying the appropriate recipient for the allocation of scarce resources, by safely navigating through the challenges that are unique to lung transplantation for coronavirus disease-2019-associated acute respiratory distress syndrome, demands a conscientious and meticulous approach. Categorizing the respiratory failure in coronavirus disease-2019 may facilitate the process of evaluation for the purpose of transplant. The progress in rescue transplants over the past two decades has greatly improved our ability to successfully perform high-risk lung transplantation.
Sprache	Englisch
Erscheinungsdatum	2021-09-01
Erscheinungsland	India
Dokumenttyp	Journal Article ; Review
ZDB-ID	2164386-6
ISSN	0973-7723 ; 0970-9134
ISSN (online)	0973-7723
ISSN	0970-9134
DOI	10.1007/s12055-021-01233-x
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Using ALE coordinate-based meta-analysis to observe resting-state brain abnormalities in subjective tinnitus.

Pandey, Himanshu R / Keshri, Amit / Singh, Anshita / Sinha, Neeraj / Kumar, Uttam

Brain imaging and behavior

2024

Abstract: The origin of tinnitus remains a topic of discussion; however, numerous resting-state functional magnetic resonance imaging (rsfMRI) studies interpret it as a disruption in neural functional connectivity. Yet, there's notable inconsistency in the resting- ...

Abstract	The origin of tinnitus remains a topic of discussion; however, numerous resting-state functional magnetic resonance imaging (rsfMRI) studies interpret it as a disruption in neural functional connectivity. Yet, there's notable inconsistency in the resting-state data across these studies. To shed light on this discrepancy, we conducted a meta-analysis of extant rsfMRI studies, aiming to identify potential regions that consistently signify core abnormalities in individuals with tinnitus. Methods: A systematic search on MEDLINE/PubMed, Google Scholar, and Scopus databases was performed to identify rsfMRI studies on tinnitus published up to October 2022. Coordinates related to the amplitude of low-frequency fluctuation (ALFF) and regional homogeneity (ReHo) brain maps that showed significant differences between tinnitus patients and controls were extracted. Meta-analysis was performed using the activation likelihood estimation method. Data were included from 17 rsfMRI studies that reported a total of 63 distinct foci in ALFF and 46 foci in ReHo. Results: Our meta-analysis revealed several regions where tinnitus patients demonstrated increased ALFF and ReHO values, both individually and collectively, when compared to control subjects. These regions encompassed the insula, middle temporal gyrus, and inferior frontal gyrus on both sides. Additionally, increased activity was also noted in the cerebellum posterior lobe bilaterally and the right superior frontal gyrus. Conclusions: This meta-analysis demonstrates a unique pattern of resting-state brain abnormalities involving both the auditory and non-auditory brain regions as neuroimaging markers, which helps understand the neuro-pathophysiological mechanisms of tinnitus.
Sprache	Englisch
Erscheinungsdatum	2024-01-03
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2377165-3
ISSN	1931-7565 ; 1931-7557
ISSN (online)	1931-7565
ISSN	1931-7557
DOI	10.1007/s11682-023-00846-7
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Opioid-free anesthesia using a combination of ketamine and dexmedetomidine in patients undergoing laparoscopic cholecystectomy: a randomized controlled trial.

K R, Vishnuraj / Singh, Kunal / Sahay, Nishant / Sinha, Chandni / Kumar, Amarjeet / Kumar, Neeraj

Anesthesia and pain medicine

2024 Band 19, Heft 2, Seite(n) 109–116

Abstract: Background: Opioids administered as bolus doses or continuous infusions are widely used for major and daycare surgeries. Opioid-free anesthesia is multimodal anesthesia and analgesia that does not use opioids, benefiting patients from opioid-related ... ...

Abstract	Background: Opioids administered as bolus doses or continuous infusions are widely used for major and daycare surgeries. Opioid-free anesthesia is multimodal anesthesia and analgesia that does not use opioids, benefiting patients from opioid-related adverse effects. We compared the postoperative analgesic requirements of patients scheduled for elective laparoscopic cholecystectomy under opioid-free and opioid-based anesthesia. Methods: Study included 88 patients aged 18-60 years with American Society of Anesthesiologists physical status 1 and 2 who underwent elective laparoscopic cholecystectomy. Participants were randomly divided into two groups with 44 in each. The opioid-free group was administered an intravenous bolus of ketamine and dexmedetomidine, whereas fentanyl was used in opioid group. Primary outcome was to compare the total amount of fentanyl consumed by both groups during 6 h postoperative period. Episodes of postoperative nausea and vomiting (PONV) and vital signs were noted throughout the postoperative period to analyze the secondary outcomes. Results: Both groups had similar demographic characteristics. The opioid-free group required lesser analgesia within the first 2 h (61.4 ± 17.4 vs. 79.0 ± 19.4 of fentanyl, P < 0.001), which was statistically significant. However, fentanyl consumption was comparable between the groups at 6 h (152 ± 28.2 vs. 164 ± 33.4, P = 0.061). Compared with 4.5% of the participants in the opioid-free group, 34% of those in the opioid-based group developed moderate PONV. Conclusions: Opioid-free anesthesia in patients undergoing laparoscopic cholecystectomy reduced the requirement of analgesia in first two-hour postoperative period and was associated with decreased PONV.
Sprache	Englisch
Erscheinungsdatum	2024-04-19
Erscheinungsland	Korea (South)
Dokumenttyp	Journal Article
ISSN	2383-7977
ISSN (online)	2383-7977
DOI	10.17085/apm.23097
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Pharmacometric analyses and clinical evidence for brigatinib dosing in anaplastic lymphoma kinase-positive non-small cell lung cancer.

Gupta, Neeraj / Hanley, Michael J / Sinha, Vikram

British journal of clinical pharmacology

2022 Band 88, Heft 8, Seite(n) 3922–3923

Mesh-Begriff(e)	Anaplastic Lymphoma Kinase ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/pathology ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/pathology ; Organophosphorus Compounds ; Protein Kinase Inhibitors/therapeutic use ; Pyrimidines
Chemische Substanzen	Organophosphorus Compounds ; Protein Kinase Inhibitors ; Pyrimidines ; Anaplastic Lymphoma Kinase (EC 2.7.10.1) ; brigatinib (HYW8DB273J)
Sprache	Englisch
Erscheinungsdatum	2022-03-29
Erscheinungsland	England
Dokumenttyp	Letter ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	188974-6
ISSN	1365-2125 ; 0306-5251 ; 0264-3774
ISSN (online)	1365-2125
ISSN	0306-5251 ; 0264-3774
DOI	10.1111/bcp.15322
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1118: Hefte anzeigen

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Artikel ; Online: Unraveling Water-Mediated

Dwivedi, Navneet / Dubey, Richa / Srivastava, Seema / Sinha, Neeraj

ACS omega

2022 Band 7, Heft 19, Seite(n) 16678–16688

Abstract: Bone is a dynamic tissue composed of organic proteins (mainly type I collagen), inorganic components (hydroxyapatite), lipids, and water that undergoes a continuous rebuilding process over the lifespan of human beings. Bone mineral is mainly composed of ... ...

Abstract	Bone is a dynamic tissue composed of organic proteins (mainly type I collagen), inorganic components (hydroxyapatite), lipids, and water that undergoes a continuous rebuilding process over the lifespan of human beings. Bone mineral is mainly composed of a crystalline apatitic core surrounded by an amorphous surface layer. The supramolecular arrangement of different constituents gives rise to its unique mechanical properties, which become altered in various bone-related disease conditions. Many of the interactions among the different components are poorly understood. Recently, solid-state nuclear magnetic resonance (ssNMR) has become a popular spectroscopic tool for studying bone. In this article, we present a study probing the interaction of water molecules with amorphous and crystalline parts of the bone mineral through
Sprache	Englisch
Erscheinungsdatum	2022-05-02
Erscheinungsland	United States
Dokumenttyp	Journal Article
ISSN	2470-1343
ISSN (online)	2470-1343
DOI	10.1021/acsomega.2c01133
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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