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  1. Artikel ; Online: Interesting case from Argentina: Kidney transplant recipient with skin lesions-A Latin American perspective.

    Radisic, Marcelo Víctor / Santoro Lopes, Guilherme / Hasslocher-Moreno, Alejandro Marcel / Eichenberger, Emily M / Hall, Victoria G / Pujato, Natalia Rosana / Clemente, Wanessa Trindade

    Transplant infectious disease : an official journal of the Transplantation Society

    2024  Band 26, Heft 2, Seite(n) e14243

    Abstract: This is a case of a kidney transplant recipient who presented with skin lesions, low-grade fevers, and pancytopenia 2 months after his transplant. ...

    Abstract This is a case of a kidney transplant recipient who presented with skin lesions, low-grade fevers, and pancytopenia 2 months after his transplant.
    Mesh-Begriff(e) Humans ; Argentina ; Kidney Transplantation/adverse effects ; Latin America
    Sprache Englisch
    Erscheinungsdatum 2024-02-26
    Erscheinungsland Denmark
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.14243
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Purification and use of crude green glycerol from the transesterification of triglycerides in the formulation of an alcohol gel hand sanitizer.

    Trindade Mazala, Tassio / Costa Viana, Mateus / Carneiro, Guilherme / Lee Nelson, David / de Freitas-Marques, Maria B / De Martinis, Bruno Spinosa / Florêncio, Jacques / Mazzé, Fernanda Marur / da Silva, Severino G Domingos / Barbosa, Sandro L

    Scientific reports

    2024  Band 14, Heft 1, Seite(n) 5510

    Abstract: ... glycerol was purified using chemical and physical treatments. The sanitizer was prepared using 71.100 g ... of 99.3° GL ethanol, 28.0 g H ...

    Abstract The aim of this study was to produce an alcohol gel hand sanitizer containing green glycerol. Crude glycerol was purified using chemical and physical treatments. The sanitizer was prepared using 71.100 g of 99.3° GL ethanol, 28.0 g H
    Mesh-Begriff(e) Glycerol ; Hand Sanitizers ; Triglycerides ; Ethanol ; Gels ; Ethanolamines
    Chemische Substanzen Glycerol (PDC6A3C0OX) ; triethanolamine (9O3K93S3TK) ; Hand Sanitizers ; Triglycerides ; Ethanol (3K9958V90M) ; Gels ; Ethanolamines
    Sprache Englisch
    Erscheinungsdatum 2024-03-06
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-49422-5
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Microsurgical Resection of Giant Petroclival Meningioma via the Posterior Petrosal Approach: 2-Dimensional Operative Video.

    Ceccato, Guilherme H W / da Trindade, Érico S G G / Foltran, Rodrigo S / Pereira, Rodrigo V / Borba, Luis A B

    World neurosurgery

    2022  Band 166, Seite(n) 191

    Abstract: Petroclival meningiomas are challenging deep-seated lesions related to many critical neurovascular structures of the skull base. ...

    Abstract Petroclival meningiomas are challenging deep-seated lesions related to many critical neurovascular structures of the skull base.
    Mesh-Begriff(e) Humans ; Male ; Meningeal Neoplasms/diagnostic imaging ; Meningeal Neoplasms/surgery ; Meningioma/diagnostic imaging ; Meningioma/surgery ; Middle Aged ; Neurosurgical Procedures/methods ; Petrous Bone/diagnostic imaging ; Petrous Bone/pathology ; Petrous Bone/surgery ; Skull Base Neoplasms/diagnostic imaging ; Skull Base Neoplasms/pathology ; Skull Base Neoplasms/surgery
    Sprache Englisch
    Erscheinungsdatum 2022-08-11
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Video-Audio Media
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2022.08.008
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Multimodal treatment of a pediatric posterior fossa arteriovenous malformation employing endovascular and microsurgical techniques.

    Demartini, Zeferino / Ceccato, Guilherme H W / da Trindade, Érico S G G / Borba, Luis A B

    Neurosurgical focus: Video

    2021  Band 4, Heft 1, Seite(n) V17

    Abstract: Intracranial hemorrhage is the most common presentation of posterior fossa arteriovenous malformations (AVMs) and may have serious consequences. The authors present a case of a 7-year-old girl with headache, vomiting, dysmetria, and ataxia due to a ... ...

    Abstract Intracranial hemorrhage is the most common presentation of posterior fossa arteriovenous malformations (AVMs) and may have serious consequences. The authors present a case of a 7-year-old girl with headache, vomiting, dysmetria, and ataxia due to a ruptured cerebellar grade III AVM. After two sessions of embolization, the patient underwent total microsurgical resection through a suboccipital craniotomy. There were no additional postoperative deficits, and the patient improved progressively during 6 months of rehabilitation. These challenging lesions should be removed after rupture, especially in children with long-term cumulative risk of rebleeding. Multimodal treatment reduces the perioperative bleeding, allowing better outcomes for pediatric AVM. The video can be found here: https://youtu.be/HQWnjD8ENZQ.
    Sprache Englisch
    Erscheinungsdatum 2021-01-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2643-5217
    ISSN (online) 2643-5217
    DOI 10.3171/2020.10.FOCVID2064
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: DENTAL INTRAORAL EXPOSURES IN PORTUGAL: FROM 1990 TO 2018.

    Trindade, Hugo / Coutinho, Guilherme

    Radiation protection dosimetry

    2019  Band 185, Heft 4, Seite(n) 452–455

    Abstract: Data from dental intraoral radiography quality controls was gathered from 1201 units (22% of the licensed X-ray units existing in Portugal), using film and digital image systems, between 2016 and 2018. The median incident air KERMA for standard superior ... ...

    Abstract Data from dental intraoral radiography quality controls was gathered from 1201 units (22% of the licensed X-ray units existing in Portugal), using film and digital image systems, between 2016 and 2018. The median incident air KERMA for standard superior molar tooth was evaluated in 0.9 mGy with the value of 1.3 mGy as the upper quartile. Comparisons with a 1990 published survey from dental exposures in Portugal were made. A 85% reduction for incident air KERMA per exposure was observed (6.0 mGy for the 1990 survey), which can be attributed to technical advances in the X-ray image receptors, as well as the implementation of legal requirements for technical acceptability of radiological units. It was also observed an increase of X-ray exams, which is related to an increase of dental practitioners, available radiological equipment and the level of dental healthcare.
    Mesh-Begriff(e) Humans ; Portugal ; Quality Control ; Radiation Dosage ; Radiography, Dental/methods ; Radiography, Dental/statistics & numerical data ; Radiography, Dental, Digital/methods ; Radiography, Dental, Digital/statistics & numerical data ; Radiology ; Radiometry ; Surveys and Questionnaires ; X-Ray Intensifying Screens ; X-Rays
    Sprache Englisch
    Erscheinungsdatum 2019-09-06
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 225912-6
    ISSN 1742-3406 ; 0144-8420
    ISSN (online) 1742-3406
    ISSN 0144-8420
    DOI 10.1093/rpd/ncz033
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Facial Expressions of Horses Using Weighted Multivariate Statistics for Assessment of Subtle Local Pain Induced by Polylactide-Based Polymers Implanted Subcutaneously.

    Carvalho, Júlia R G / Trindade, Pedro H E / Conde, Gabriel / Antonioli, Marina L / Funnicelli, Michelli I G / Dias, Paula P / Canola, Paulo A / Chinelatto, Marcelo A / Ferraz, Guilherme C

    Animals : an open access journal from MDPI

    2022  Band 12, Heft 18

    Abstract: Facial-expression-based analysis has been widely applied as a pain coding system in horses. Herein, we aimed to identify pain in horses undergoing subcutaneously polylactide-based polymer implantation. The sham group was submitted only to surgical ... ...

    Abstract Facial-expression-based analysis has been widely applied as a pain coding system in horses. Herein, we aimed to identify pain in horses undergoing subcutaneously polylactide-based polymer implantation. The sham group was submitted only to surgical incision. The horses were filmed before and 24 and 48 h after implantation. Five statistical methods for evaluating their facial expressions (FEs) were tested. Primarily, three levels of scores (0, 1, and 2) were applied to the seven FEs (ear movements, eyebrow tension, orbicularis tension, dilated nostrils, eye opening, muzzle tension, and masticatory muscles tension). Subsequently, the scores of the seven FEs were added (SUM). Afterwards, principal component analysis (PCoA) was performed using the scores of the seven FEs obtained using the first method. Subsequently, weights were created for each FE, based on each variable's contribution variability obtained from the PCoA (SUM.W). Lastly, we applied a general score (GFS) to the animal's face (0 = without pain; 1 = moderate pain; 2 = severe pain). The mechanical nociceptive threshold (MNT) and cutaneous temperature (CT) values were collected at the same moments. The results show no intra- or intergroup differences, when evaluating each FE separately or in the GFS. In the intragroup comparison and 48 h after implantation, the control group showed higher values for SUM, PCoA, and SUM.W, although the horses implanted with polymers displayed more obvious alterations in the CT and MNT. Our findings show that the five statistical strategies used to analyze the faces of the horses were not able to detect low-grade inflammatory pain.
    Sprache Englisch
    Erscheinungsdatum 2022-09-13
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani12182400
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: COVID-19: therapeutic approaches description and discussion.

    Trindade, Guilherme G / Caxito, Samyra M C / Xavier, Alessandra Rejane E O / Xavier, Mauro A S / BrandÃo, Fabiana

    Anais da Academia Brasileira de Ciencias

    2020  Band 92, Heft 2, Seite(n) e20200466

    Abstract: COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" ... ...

    Abstract COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" pandemic in 1918. Researchers globally are dedicating efforts to the search for an effective treatment for COVID-19. Drugs already used in a clinical setting for other pathologies have been tested as a new therapeutic approach against SARS-CoV-2, setting off a frenzy over the preliminary data of different studies. This work aims to compile and discuss the data published thus far. Despite the potential effects of some antivirals and antiparasitic against COVID-19, clinical studies must confirm real effectiveness. However, non-pharmacological approaches have proven to be the most efficient strategy to date.
    Mesh-Begriff(e) Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Antiparasitic Agents/administration & dosage ; Antiparasitic Agents/chemistry ; Antiparasitic Agents/pharmacology ; Antiviral Agents/administration & dosage ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Betacoronavirus/drug effects ; COVID-19 ; Coronavirus Infections/drug therapy ; Humans ; Macrolides/administration & dosage ; Macrolides/chemistry ; Macrolides/pharmacology ; Pandemics ; Pneumonia, Viral/drug therapy ; SARS-CoV-2 ; Serine Proteinase Inhibitors/administration & dosage ; Serine Proteinase Inhibitors/chemistry ; Serine Proteinase Inhibitors/pharmacology
    Chemische Substanzen Anti-Bacterial Agents ; Antiparasitic Agents ; Antiviral Agents ; Macrolides ; Serine Proteinase Inhibitors
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-06-15
    Erscheinungsland Brazil
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2046885-4
    ISSN 1678-2690 ; 0001-3765
    ISSN (online) 1678-2690
    ISSN 0001-3765
    DOI 10.1590/0001-3765202020200466
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: COVID-19

    TRINDADE, GUILHERME G. / CAXITO, SAMYRA M.C. / XAVIER, ALESSANDRA REJANE E.O. / XAVIER, MAURO A.S. / BRANDÃO, FABIANA

    Anais da Academia Brasileira de Ciências v.92 n.2 2020

    therapeutic approaches description and discussion

    2020  

    Abstract: Abstract Abstract: COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since ...

    Abstract Abstract Abstract: COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the “Spanish flu” pandemic in 1918. Researchers globally are dedicating efforts to the search for an effective treatment for COVID-19. Drugs already used in a clinical setting for other pathologies have been tested as a new therapeutic approach against SARS-CoV-2, setting off a frenzy over the preliminary data of different studies. This work aims to compile and discuss the data published thus far. Despite the potential effects of some antivirals and antiparasitic against COVID-19, clinical studies must confirm real effectiveness. However, non-pharmacological approaches have proven to be the most efficient strategy to date.
    Schlagwörter antivirals ; antiparasitic ; COVID-19 ; SARS-CoV-2 ; therapeutic approaches ; covid19
    Sprache Englisch
    Erscheinungsdatum 2020-01-01
    Verlag Academia Brasileira de Ciências
    Erscheinungsland br
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel: Facial Expressions of Horses Using Weighted Multivariate Statistics for Assessment of Subtle Local Pain Induced by Polylactide-Based Polymers Implanted Subcutaneously

    Carvalho, Júlia R. G. / Trindade, Pedro H. E. / Conde, Gabriel / Antonioli, Marina L. / Funnicelli, Michelli I. G. / Dias, Paula P. / Canola, Paulo A. / Chinelatto, Marcelo A. / Ferraz, Guilherme C.

    Animals. 2022 Sept. 13, v. 12, no. 18

    2022  

    Abstract: Facial-expression-based analysis has been widely applied as a pain coding system in horses. Herein, we aimed to identify pain in horses undergoing subcutaneously polylactide-based polymer implantation. The sham group was submitted only to surgical ... ...

    Abstract Facial-expression-based analysis has been widely applied as a pain coding system in horses. Herein, we aimed to identify pain in horses undergoing subcutaneously polylactide-based polymer implantation. The sham group was submitted only to surgical incision. The horses were filmed before and 24 and 48 h after implantation. Five statistical methods for evaluating their facial expressions (FEs) were tested. Primarily, three levels of scores (0, 1, and 2) were applied to the seven FEs (ear movements, eyebrow tension, orbicularis tension, dilated nostrils, eye opening, muzzle tension, and masticatory muscles tension). Subsequently, the scores of the seven FEs were added (SUM). Afterwards, principal component analysis (PCoA) was performed using the scores of the seven FEs obtained using the first method. Subsequently, weights were created for each FE, based on each variable’s contribution variability obtained from the PCoA (SUM.W). Lastly, we applied a general score (GFS) to the animal’s face (0 = without pain; 1 = moderate pain; 2 = severe pain). The mechanical nociceptive threshold (MNT) and cutaneous temperature (CT) values were collected at the same moments. The results show no intra- or intergroup differences, when evaluating each FE separately or in the GFS. In the intragroup comparison and 48 h after implantation, the control group showed higher values for SUM, PCoA, and SUM.W, although the horses implanted with polymers displayed more obvious alterations in the CT and MNT. Our findings show that the five statistical strategies used to analyze the faces of the horses were not able to detect low-grade inflammatory pain.
    Schlagwörter animals ; ears ; face ; multivariate analysis ; pain ; polymers ; principal component analysis ; temperature
    Sprache Englisch
    Erscheinungsverlauf 2022-0913
    Erscheinungsort Multidisciplinary Digital Publishing Institute
    Dokumenttyp Artikel
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani12182400
    Datenquelle NAL Katalog (AGRICOLA)

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  10. Artikel ; Online: Praziquantel pharmacotherapy reduces systemic osteopontin levels and liver collagen content in murine schistosomiasis mansoni.

    Pereira, Thiago A / Vaz de Melo Trindade, Guilherme / Trindade Santos, Elisangela / Pereira, Fausto E L / Souza, Márcia Maria de

    International journal for parasitology

    2021  Band 51, Heft 6, Seite(n) 437–440

    Abstract: The pathogenesis of schistosomiasis and the mechanism of disease regression after Praziquantel pharmacotherapy are not fully elucidated. Schistosoma mansoni egg antigens directly stimulate the expression of the profibrogenic molecule osteopontin (OPN), ... ...

    Abstract The pathogenesis of schistosomiasis and the mechanism of disease regression after Praziquantel pharmacotherapy are not fully elucidated. Schistosoma mansoni egg antigens directly stimulate the expression of the profibrogenic molecule osteopontin (OPN), and systemic OPN levels strongly correlate with disease severity, suggesting its use as a potential morbidity biomarker. In this study, we investigated the impact of Praziquantel use on systemic OPN levels and on liver collagen deposition in chronic murine schistosomiasis. Praziquantel treatment significantly reduced systemic OPN levels and liver collagen deposition, indicating that OPN could be a reliable tool for monitoring PZQ efficacy and fibrosis regression in murine schistosomiasis.
    Mesh-Begriff(e) Animals ; Anthelmintics/therapeutic use ; Collagen/therapeutic use ; Liver ; Mice ; Osteopontin ; Praziquantel/therapeutic use ; Schistosoma mansoni ; Schistosomiasis mansoni/drug therapy
    Chemische Substanzen Anthelmintics ; Osteopontin (106441-73-0) ; Praziquantel (6490C9U457) ; Collagen (9007-34-5)
    Sprache Englisch
    Erscheinungsdatum 2021-01-23
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 120518-3
    ISSN 1879-0135 ; 0020-7519
    ISSN (online) 1879-0135
    ISSN 0020-7519
    DOI 10.1016/j.ijpara.2020.11.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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