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  1. Book ; Online: Pollen ages and depths in ODP Site 184-1144, supplementary data to: Sun, Xiangjun; Luo, Yunli; Huang, Fei; Tian, Jun; Wang, Pinxian (2003): Deep-sea pollen from the South China Sea: Pleistocene indicators of East Asian monsoon. Marine Geology, 201(1-3), 97-118

    Sun, Xiangjun / Huang, Fei / Luo, Yunli / Tian, Jun / Wang, Pinxian

    2003  

    Abstract: A high-resolution pollen record (sampling interval averages 820 years) has been obtained from ODP Site 1144 (water depth 2037 m), northern South China Sea. The 504-m sequence (in composition length) covers the last 1.03 million years according to ... ...

    Abstract A high-resolution pollen record (sampling interval averages 820 years) has been obtained from ODP Site 1144 (water depth 2037 m), northern South China Sea. The 504-m sequence (in composition length) covers the last 1.03 million years according to micropaleontological and isotopic stratigraphy. The pollen assemblages are characterized by high proportions of Pinus and herb pollen, and by their frequent alternations. Based on these alternations, 29 pollen zones have been recognized that are closely correlated to the Marine Oxygen Isotope Stages (MIS) 1-29. Pinus- dominant pollen zones correspond to interglacial periods with lighter delta18O values, while herb-marked ones relate to the heavier delta18O stages assigned to glacials. Judging from the pollen data, the exposed northern continental shelf of the South China Sea during the glacials was covered by grassland, and the extensive northern shelf has formed only since MIS 6 (ca. 150 ka), probably as a result of tectonic subsidence. Tree pollen influx values are indicative of winter monsoon which began to intensify 600 ka ago. The summer monsoon variations can be approximated by the fern percentage within the total pollen and spore abundance, and the result shows high values in general occurring at interglacials, with the maxima at MIS 15, 5e and 1. The relatively high fern percentage with smaller amplitude in variations before 600 ka might suggest more stable humid conditions before the intensification of winter monsoon.
    Language English
    Dates of publication 2003-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/S0025-3227(03)00211-1
    DOI 10.1594/PANGAEA.738719
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Article ; Online: The effects of medication therapy management on medication utilization among Medicare beneficiaries with HIV/AIDS.

    Zhang, Xiangjun / Wang, Junling

    Journal of the American Pharmacists Association : JAPhA

    2024  Volume 64, Issue 2, Page(s) 463–470.e2

    Abstract: Background: Medicare Part D plans are required to provide medication therapy management (MTM) programs to eligible beneficiaries to optimize medication utilization. MTM programs' effects on medication utilization among older persons living with HIV/AIDS ...

    Abstract Background: Medicare Part D plans are required to provide medication therapy management (MTM) programs to eligible beneficiaries to optimize medication utilization. MTM programs' effects on medication utilization among older persons living with HIV/AIDS (PLWHs) remain unclear.
    Objective: This study examined the effects of the Medicare MTM programs on medication utilization among PLWHs.
    Methods: This study analyzed 2017 Medicare databases linked to the Area Health Resources Files. Recipients and nonrecipients of the MTM services were compared on their medication utilization: adherence to antiretroviral medications, drug-drug interactions (DDI), and concurrent use of opioids and benzodiazepines. The intervention group comprised recipients of the MTM services, and the control group was nonrecipients meeting the eligibility criteria. A propensity score with a ratio of 1:2 between the intervention and control groups was used to identify study groups with balanced characteristics. A logistic regression was used to control for patient/community characteristics.
    Results: After matching, the intervention and comparison groups comprised 3298 and 6596 beneficiaries for the antiretroviral adherence measure, 809 and 1618 for the DDI measure, and 691 and 1382 for the concurrent use of opioids and benzodiazepines measure. The intervention was associated with higher odds of adherence to antiretroviral medications (adjusted odds ratio = 1.15, 95% CI = 1.04-1.26), and no concurrent use of opioids and benzodiazepines (adjusted odds ratio = 1.255, 95% CI = 1.005-1.568). The study groups did not differ on no DDI (adjusted odds ratio = 0.95, 95% CI = 0.74-1.20).
    Conclusions: Medicare MTM programs effectively improved medication utilization among PLWHs. Future studies should explore the long-term effects of the program.
    MeSH term(s) Humans ; Aged ; United States ; Aged, 80 and over ; Medication Therapy Management ; Acquired Immunodeficiency Syndrome/drug therapy ; Medicare Part D ; Eligibility Determination ; Benzodiazepines/therapeutic use
    Chemical Substances Benzodiazepines (12794-10-4)
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2118585-2
    ISSN 1544-3450 ; 1544-3191 ; 1086-5802
    ISSN (online) 1544-3450
    ISSN 1544-3191 ; 1086-5802
    DOI 10.1016/j.japh.2023.12.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Current state of immune checkpoints therapy for glioblastoma

    He Wang / Jing Yang / Xiangjun Li / Hai Zhao

    Heliyon, Vol 10, Iss 2, Pp e24729- (2024)

    2024  

    Abstract: Glioblastoma (GBM), one of the most aggressive forms of brain cancer, has limited treatment options. Recent years have witnessed the remarkable success of checkpoint inhibitor immunotherapy across various cancer types. Against this backdrop, several ... ...

    Abstract Glioblastoma (GBM), one of the most aggressive forms of brain cancer, has limited treatment options. Recent years have witnessed the remarkable success of checkpoint inhibitor immunotherapy across various cancer types. Against this backdrop, several clinical trials investigating checkpoint inhibitors for GBM are underway in multiple countries. Furthermore, the integration of immunotherapy with traditional treatment approaches is now emerging as a highly promising strategy. This review summarizes the latest advancements in checkpoint inhibitor immunotherapy for GBM treatment. We provide a concise yet comprehensive overview of current GBM immunotherapy options. Additionally, this review underscores combination strategies and potential biomarkers for predicting response and resistance in GBM immunotherapies.
    Keywords GBM ; Checkpoint inhibitor ; Immunotherapy ; Combination therapy ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Circulating fibroblasts present neutrophil-like features in severe COVID-19 cases revealed by single-cell landscape analyses.

    Liu, Xiangjun / Gui, Jingang / Wang, Xiaolin

    Genes & diseases

    2023  

    Language English
    Publishing date 2023-03-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2821806-1
    ISSN 2352-3042 ; 2352-3042
    ISSN (online) 2352-3042
    ISSN 2352-3042
    DOI 10.1016/j.gendis.2023.02.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Current state of immune checkpoints therapy for glioblastoma.

    Wang, He / Yang, Jing / Li, Xiangjun / Zhao, Hai

    Heliyon

    2024  Volume 10, Issue 2, Page(s) e24729

    Abstract: Glioblastoma (GBM), one of the most aggressive forms of brain cancer, has limited treatment options. Recent years have witnessed the remarkable success of checkpoint inhibitor immunotherapy across various cancer types. Against this backdrop, several ... ...

    Abstract Glioblastoma (GBM), one of the most aggressive forms of brain cancer, has limited treatment options. Recent years have witnessed the remarkable success of checkpoint inhibitor immunotherapy across various cancer types. Against this backdrop, several clinical trials investigating checkpoint inhibitors for GBM are underway in multiple countries. Furthermore, the integration of immunotherapy with traditional treatment approaches is now emerging as a highly promising strategy. This review summarizes the latest advancements in checkpoint inhibitor immunotherapy for GBM treatment. We provide a concise yet comprehensive overview of current GBM immunotherapy options. Additionally, this review underscores combination strategies and potential biomarkers for predicting response and resistance in GBM immunotherapies.
    Language English
    Publishing date 2024-01-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e24729
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Erratum: MicroRNA-423 enhances the invasiveness of hepatocellular carcinoma via regulation of BRMS1.

    Sun, Xiangjun / Wang, Mingchun / Liu, Haiyan / Wang, Jian

    American journal of translational research

    2023  Volume 15, Issue 2, Page(s) 1533–1534

    Abstract: This corrects the article on p. 5576 in vol. 9, PMID: 29312509.]. ...

    Abstract [This corrects the article on p. 5576 in vol. 9, PMID: 29312509.].
    Language English
    Publishing date 2023-02-15
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2471058-1
    ISSN 1943-8141
    ISSN 1943-8141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Predicting the current fishable habitat distribution of Antarctic toothfish (

    Liu, Jie / Zhu, Ancheng / Wang, Xitao / Zhou, Xiangjun / Chen, Lu

    PeerJ

    2024  Volume 12, Page(s) e17131

    Abstract: Global warming continues to exert unprecedented impacts on marine habitats. Species distribution models (SDMs) are proven powerful in predicting habitat distribution for marine demersal species under climate change impacts. The Antarctic toothfish, ...

    Abstract Global warming continues to exert unprecedented impacts on marine habitats. Species distribution models (SDMs) are proven powerful in predicting habitat distribution for marine demersal species under climate change impacts. The Antarctic toothfish,
    MeSH term(s) Animals ; Climate Change ; Antarctic Regions ; Ecosystem ; Perciformes ; Oceans and Seas
    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.17131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Review of Cerebrospinal Fluid Circulation and the Pathogenesis of Congenital Hydrocephalus.

    Zhang, Mingzhao / Hu, Xiangjun / Wang, Lifeng

    Neurochemical research

    2024  Volume 49, Issue 5, Page(s) 1123–1136

    Abstract: The brain's ventricles are filled with a colorless fluid known as cerebrospinal fluid (CSF). When there is an excessive accumulation of CSF in the ventricles, it can result in high intracranial pressure, ventricular enlargement, and compression of the ... ...

    Abstract The brain's ventricles are filled with a colorless fluid known as cerebrospinal fluid (CSF). When there is an excessive accumulation of CSF in the ventricles, it can result in high intracranial pressure, ventricular enlargement, and compression of the surrounding brain tissue, leading to potential damage. This condition is referred to as hydrocephalus. Hydrocephalus is classified into two categories: congenital and acquired. Congenital hydrocephalus (CH) poses significant challenges for affected children and their families, particularly in resource-poor countries. Recognizing the psychological and economic impacts is crucial for developing interventions and support systems that can help alleviate the distress and burden faced by these families. As our understanding of CSF production and circulation improves, we are gaining clearer insights into the causes of CH. In this article, we will summarize the current knowledge regarding CSF circulation pathways and the underlying causes of CH. The main causes of CH include abnormalities in the FoxJ1 pathway of ventricular cilia, dysfunctions in the choroid plexus transporter Na
    MeSH term(s) Child ; Humans ; Hydrocephalus/cerebrospinal fluid ; Hydrocephalus/pathology ; Brain/pathology ; Choroid Plexus/metabolism ; Choroid Plexus/pathology ; Head ; Cerebrospinal Fluid
    Language English
    Publishing date 2024-02-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 199335-5
    ISSN 1573-6903 ; 0364-3190
    ISSN (online) 1573-6903
    ISSN 0364-3190
    DOI 10.1007/s11064-024-04113-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Impact of Sarcopenia on Prognosis in Primary Hepatocellular Carcinoma Patients Treated with Transcatheter Arterial Chemoembolization: A Single Center Retrospective Study.

    Bai, Yaowei / Liu, Jiacheng / Wang, Ying / Zhou, Binqian / Liu, Xiaoming / Dong, Xiangjun / Zheng, Chuansheng

    Journal of Cancer

    2024  Volume 15, Issue 7, Page(s) 1837–1847

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2024-02-04
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2573318-7
    ISSN 1837-9664
    ISSN 1837-9664
    DOI 10.7150/jca.92976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The Resource Utilization of Poplar Leaves for CO

    Wang, Xia / Kong, Fanyuan / Zeng, Wulan / Zhang, Huaxiang / Xin, Chunling / Kong, Xiangjun

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 9

    Abstract: Every late autumn, fluttering poplar leaves scatter throughout the campus and city streets. In this work, poplar leaves were used as the raw material, while ... ...

    Abstract Every late autumn, fluttering poplar leaves scatter throughout the campus and city streets. In this work, poplar leaves were used as the raw material, while H
    Language English
    Publishing date 2024-04-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29092024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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