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  1. Artikel ; Online: 4 Cases of Aortic Thrombosis in Patients With COVID-19.

    Woehl, Bastien / Lawson, Bree / Jambert, Lucas / Tousch, Jonathan / Ghassani, Afif / Hamade, Amer

    JACC. Case reports

    2020  Band 2, Heft 9, Seite(n) 1397–1401

    Abstract: Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infection between ... ...

    Abstract Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infection between March 26 and April 12, 2020, in Mulhouse, France. (
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-06-08
    Erscheinungsland Netherlands
    Dokumenttyp Case Reports
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2020.06.003
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Antiphospholipid antibodies in patients with coronavirus disease 2019 infection hospitalized in conventional unit.

    Hamadé, Amer / Woehl, Bastien / Harzallah, Ines / Talbot, Marjolaine / Tousch, Jonathan / Jambert, Lucas

    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis

    2020  Band 32, Heft 2, Seite(n) 73–79

    Abstract: Antiphospholipid (aPL) antibodies can arise transiently at times of viral diseases. The objective of this work was to evaluate the incidence of aPL antibodies in patients hospitalized in conventional unit for coronavirus disease 2019 (COVID-19) infection ...

    Abstract Antiphospholipid (aPL) antibodies can arise transiently at times of viral diseases. The objective of this work was to evaluate the incidence of aPL antibodies in patients hospitalized in conventional unit for coronavirus disease 2019 (COVID-19) infection and confirmed venous thromboembolic events (VTE) associated with aPL antibodies. 41 patients infected with COVID-19 were tested for aPL antibodies. None had reported history of aPL syndrome. Arterial and venous duplex ultrasound of lower limbs was performed in all patients at Day 0 and Day 5. All patients had antithrombotic-prophylaxis upon admission using lower molecular weight heparin with Enoxaparin. Biological parameters were collected and analyzed. Nine patients (22%) developed VTE and seven (17%) were positive for aPL antibodies of which five had isolated positive lupus anticoagulant. The sixth patient was double aPL positive IgM anticardiolipin (147.8 U/ml) and anti-Beta2 Glyco protein 1 (97.3 U/ml) antibodies. The seventh was triple positive, IgM anticardiolipin 85.6 UI/ml, IgM anti-Beta2 Glyco protein 1 63.0 U/ml and positive lupus anticoagulant. Among the seven patients with aPL antibodies 2 (28.60%) had VTE. However, the incidence of VTE in patients negative for aPL antibodies was also significant as 20.6% (seven of 34). aPL antibodies were significantly associated with the transfer to ICUs of, P = 0.018. Not only the incidence of aPL antibodies was quite significant within our cohort, but also we observed 28.6% of VTE in aPL-positive patients. We strongly recommend routine testing for aPL antibodies in COVID-19 patients and systematic screening with duplex ultrasound search of vascular complications.
    Mesh-Begriff(e) Aged ; Aged, 80 and over ; Antibodies, Antiphospholipid/blood ; Anticoagulants/therapeutic use ; COVID-19/blood ; COVID-19/complications ; Enoxaparin/therapeutic use ; Humans ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2/isolation & purification ; Venous Thromboembolism/blood ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/etiology ; COVID-19 Drug Treatment
    Chemische Substanzen Antibodies, Antiphospholipid ; Anticoagulants ; Enoxaparin
    Sprache Englisch
    Erscheinungsdatum 2020-11-22
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1033551-1
    ISSN 1473-5733 ; 0957-5235
    ISSN (online) 1473-5733
    ISSN 0957-5235
    DOI 10.1097/MBC.0000000000000963
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: 4 Cases of Aortic Thrombosis in Patients With COVID-19

    Woehl, Bastien / Lawson, Bree / Jambert, Lucas / Tousch, Jonathan / Ghassani, Afif / Hamade, Amer

    JACC: Case Reports

    2020  Band 2, Heft 9, Seite(n) 1397–1401

    Schlagwörter covid19
    Sprache Englisch
    Verlag Elsevier BV
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ISSN 2666-0849
    DOI 10.1016/j.jaccas.2020.06.003
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Four cases of aortic thrombosis in patients with COVID-19

    Woehl, Bastien / Lawson, Bree / Jambert, Lucas / Tousch, Jonathan / Ghassani, Afif / Hamade, Amer

    JACC Case Rep

    Abstract: Abstract Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. We describe four cases of aortic thrombosis in patients admitted for COVID-19, between the ... ...

    Abstract Abstract Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. We describe four cases of aortic thrombosis in patients admitted for COVID-19, between the 26th of March and the 12th of April 2020, in Mulhouse (France).
    Schlagwörter covid19
    Verlag Elsevier; PMC; WHO
    Dokumenttyp Artikel ; Online
    Anmerkung WHO #Covidence: #574772
    DOI 10.1016/j.jaccas.2020.06.003
    Datenquelle COVID19

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  5. Artikel ; Online: The Conundrum of Occult Cancer Screening in Venous Thromboembolism: Lessons from the REMOTEV Registry.

    Cordeanu, Elena-Mihaela / Jambert, Lucas / Tousch, Jonathan / Mirea, Corina / Delatte, Alexandre / Younes, Waël / Woehl, Bastien / Harter, Claire / Frantz, Anne-Sophie / Hamade, Amer / Schini-Kerth, Valérie / Ohlmann, Patrick / Andres, Emmanuel / Stephan, Dominique

    Medicina (Kaunas, Lithuania)

    2022  Band 58, Heft 7

    Abstract: 1) Background and Objectives: Venous thromboembolism (VTE) is strongly associated with cancer, and may be the first event revealing occult neoplasia. Nonetheless, the reasonable extent of the etiological assessment after an unprovoked VTE event remains ... ...

    Abstract (1) Background and Objectives: Venous thromboembolism (VTE) is strongly associated with cancer, and may be the first event revealing occult neoplasia. Nonetheless, the reasonable extent of the etiological assessment after an unprovoked VTE event remains debated. The main objective of this study was to evaluate the incidence of occult neoplasia one year after an episode of VTE, in consecutively hospitalized patients for VTE from the REMOTEV registry. The secondary objectives were to assess the performance of the various tests used for occult cancer screening in a real-life setting and analyze the risk factors associated with the discovery of cancer and the 1-year prognosis. (2) Methods: REMOTEV is a prospective, non-interventional cohort study of patients with acute VTE. Patients included in the registry from 23 October 2013 to 28 July 2018 were analyzed after a follow-up of 12 months. Cancer detection was performed according to local practices and consisted of a limited strategy to which an abdominal ultrasound was added. In the presence of suggestive clinical manifestations, further examinations were performed on an individual basis. (3) Results: A total of 993 patients were included in the study. At 1 year, the incidence of newly diagnosed cancer was low (5.3%). Half of the detected cancers were metastatic at discovery (51%) and had a poor global prognosis (32% of mortality at 1 year). Admission pulmonary CT scans as well as (thoracic)-abdomino-pelvic CT scans (when performed) were responsible for the majority of detected cancers. Age over 65 years and the concomitant presence of an unusual site and lower-limb deep vein thrombosis were the only factors associated with occult neoplasia in this cohort. After 1-year FU, mortality was higher in cancer patients (HR 6.0 (CI 95% 3.5−10.3, p < 0.0001)), and cancer evolution was the leading cause of death in the cancer group. (4) Conclusions: In REMOTEV, VTE-revealed occult cancer prevalence was low, but similar to recent reports and associated with higher age, multiple thrombotic sites and worse prognosis.
    Mesh-Begriff(e) Aged ; Cohort Studies ; Early Detection of Cancer ; Humans ; Neoplasms/complications ; Neoplasms/diagnosis ; Neoplasms/epidemiology ; Prospective Studies ; Registries ; Risk Factors ; Venous Thromboembolism/diagnosis ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/etiology
    Sprache Englisch
    Erscheinungsdatum 2022-07-09
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58070913
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: 4 Cases of Aortic Thrombosis in Patients With COVID-19

    Woehl, Bastien / Lawson, Bree / Jambert, Lucas / Tousch, Jonathan / Ghassani, Afif / Hamade, Amer

    JACC: Case Reports

    Abstract: Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infection between ... ...

    Abstract Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. This report describes 4 cases of aortic thrombosis in patients admitted for COVID-19 infection between March 26 and April 12, 2020, in Mulhouse, France. (Level of Difficulty: Intermediate.)Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications…
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #574772
    Datenquelle COVID19

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  7. Artikel: Reply to :Aminotransferases disorders associated with venous thromboembolic events in patients infected with COVID-19.

    Hamadé, Amer / Woehl, Bastien / Talbot, Marjolaine / Bensalah, Naouel / Michel, Pierre / Obringer, Golnaz / Lehn-Hogg, Michèle / Buschenrieder, Nathalie / Issa, Mahdi / Tousch, Jonathan / Stephan, Dominique / Jambert, Lucas

    Annals of hepatology

    2021  Band 23, Seite(n) 100334

    Mesh-Begriff(e) COVID-19 ; Humans ; SARS-CoV-2 ; Transaminases ; Venous Thromboembolism/diagnosis ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/etiology ; Venous Thrombosis/diagnosis ; Venous Thrombosis/etiology
    Chemische Substanzen Transaminases (EC 2.6.1.-)
    Sprache Englisch
    Erscheinungsdatum 2021-02-20
    Erscheinungsland Mexico
    Dokumenttyp Letter ; Comment
    ZDB-ID 2188733-0
    ISSN 1665-2681
    ISSN 1665-2681
    DOI 10.1016/j.aohep.2021.100334
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: The Conundrum of Occult Cancer Screening in Venous Thromboembolism

    Elena-Mihaela Cordeanu / Lucas Jambert / Jonathan Tousch / Corina Mirea / Alexandre Delatte / Waël Younes / Bastien Woehl / Claire Harter / Anne-Sophie Frantz / Amer Hamade / Valérie Schini-Kerth / Patrick Ohlmann / Emmanuel Andres / Dominique Stephan

    Medicina, Vol 58, Iss 7, p

    Lessons from the REMOTEV Registry

    2022  Band 913

    Abstract: 1) Background and Objectives : Venous thromboembolism (VTE) is strongly associated with cancer, and may be the first event revealing occult neoplasia. Nonetheless, the reasonable extent of the etiological assessment after an unprovoked VTE event remains ...

    Abstract (1) Background and Objectives : Venous thromboembolism (VTE) is strongly associated with cancer, and may be the first event revealing occult neoplasia. Nonetheless, the reasonable extent of the etiological assessment after an unprovoked VTE event remains debated. The main objective of this study was to evaluate the incidence of occult neoplasia one year after an episode of VTE, in consecutively hospitalized patients for VTE from the REMOTEV registry. The secondary objectives were to assess the performance of the various tests used for occult cancer screening in a real-life setting and analyze the risk factors associated with the discovery of cancer and the 1-year prognosis. (2) Methods : REMOTEV is a prospective, non-interventional cohort study of patients with acute VTE. Patients included in the registry from 23 October 2013 to 28 July 2018 were analyzed after a follow-up of 12 months. Cancer detection was performed according to local practices and consisted of a limited strategy to which an abdominal ultrasound was added. In the presence of suggestive clinical manifestations, further examinations were performed on an individual basis. (3) Results : A total of 993 patients were included in the study. At 1 year, the incidence of newly diagnosed cancer was low (5.3%). Half of the detected cancers were metastatic at discovery (51%) and had a poor global prognosis (32% of mortality at 1 year). Admission pulmonary CT scans as well as (thoracic)-abdomino-pelvic CT scans (when performed) were responsible for the majority of detected cancers. Age over 65 years and the concomitant presence of an unusual site and lower-limb deep vein thrombosis were the only factors associated with occult neoplasia in this cohort. After 1-year FU, mortality was higher in cancer patients (HR 6.0 (CI 95% 3.5–10.3, p < 0.0001)), and cancer evolution was the leading cause of death in the cancer group. (4) Conclusions : In REMOTEV, VTE-revealed occult cancer prevalence was low, but similar to recent reports and associated with higher age, ...
    Schlagwörter occult cancer ; venous thromboembolism ; pulmonary embolism ; screening ; Medicine (General) ; R5-920
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2022-07-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Reply to :Aminotransferases disorders associated with venous thromboembolic events in patients infected with COVID-19

    Amer Hamadé / Bastien Woehl / Marjolaine Talbot / Naouel Bensalah / Pierre Michel / Golnaz Obringer / Michèle Lehn-Hogg / Nathalie Buschenrieder / Mahdi Issa / Jonathan Tousch / Dominique Stephan / Lucas Jambert

    Annals of Hepatology, Vol 23, Iss , Pp 100334- (2021)

    2021  

    Schlagwörter Specialties of internal medicine ; RC581-951
    Sprache Englisch
    Erscheinungsdatum 2021-07-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Withdrawal Notice: Is There a Link between Lung Parenchyma Lesions, BMI, CRP and D-dimer in COVID-19 Patients Who Had Acute Pulmonary Embolism?

    Hamadé, Amer / Jambert, Lucas / Tousch, Jonathan / Feuerstein, Philippe / Hammas, Karima / Degoul, Samuel / Bensalah, Naouel / Michel, Pierre / Lehn-Hogg, Michèle / Obringer, Golnaz / Buschenrieder, Nathalie / Nusbaum, Philippe / Barakat, Nayrouz / Talbot, Marjolaine / Stephan, Dominique / Woehl, Bastien

    Cardiovascular & hematological disorders drug targets

    2021  

    Sprache Englisch
    Erscheinungsdatum 2021-08-11
    Erscheinungsland United Arab Emirates
    Dokumenttyp Journal Article
    ZDB-ID 2244164-5
    ISSN 2212-4063 ; 1871-529X
    ISSN (online) 2212-4063
    ISSN 1871-529X
    DOI 10.2174/1871529X21666210812102024
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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