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Buch ; Online: Photonic Technology for Precision Metrology

Wojtas, Jacek

2022

Schlagwörter	Technology: general issues ; History of engineering & technology ; infrared thermometer ; mid-wave infrared ; indium arsenide antimony photodiode ; uncooled thermometer ; fibreoptic coupling ; chopper stabilised op-amp ; zero-drift pre-amplifier ; ammonia detection ; NH3 ; MOX sensors ; polymer sensors ; laser absorption spectroscopy ; CRDS ; CEAS ; MUPASS ; PAS ; HOT IR detectors ; HgCdTe ; P-i-N ; BLIP condition ; 2D material photodetectors ; colloidal quantum dot photodetectors ; low-light photodetectors ; fluorescence microscopy ; time-resolved fluorescence microscopy ; hybrid photodetector (HPD) ; single-molecule fluorescence detection ; fourier ptychography ; image classification ; deep learning ; neural network ; electro-optic modulator ; frequency modulation ; displacement measuring interferometer ; quantum cascade laser ; laser controller ; infrared modulator ; laser spectroscopy ; free space optics ; photonic metrology ; accuracy ; precision ; resolution ; FTIR ; absorption spectroscopy ; gas sensors ; optoelectronic sensors
Sprache	0\|e
Umfang	1 electronic resource (126 pages)
Verlag	MDPI - Multidisciplinary Digital Publishing Institute
Erscheinungsort	Basel
Dokumenttyp	Buch ; Online
Anmerkung	English ; Open Access
HBZ-ID	HT021613361
ISBN	9783036544946 ; 3036544941
Datenquelle	ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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Artikel ; Online: Photonic Technology for Precision Metrology

Jacek Wojtas

Applied Sciences, Vol 12, Iss 4022, p

2022 Band 4022

Abstract: Precision metrology is important for understanding and monitoring various phenomena, especially in special and scientific applications. The subject of the article covers selected aspects of the study of high-resolution measurements of the absorption ... ...

Abstract	Precision metrology is important for understanding and monitoring various phenomena, especially in special and scientific applications. The subject of the article covers selected aspects of the study of high-resolution measurements of the absorption spectra and their impact on practical issues. This research is crucial for the development of new systems based on laser absorption spectroscopy methods that can detect trace amounts of matter. Some of the most important parameters describing measuring instruments are also defined and illustrated. Specific examples of measurement results are presented, taking into account the need for the highest possible resolution, accuracy and precision.
Schlagwörter	photonic metrology ; accuracy ; precision ; resolution ; FTIR ; absorption spectroscopy ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Sprache	Englisch
Erscheinungsdatum	2022-04-01T00:00:00Z
Verlag	MDPI AG
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: Time-Efficient SNR Optimization of WMS-Based Gas Sensor Using a Genetic Algorithm.

Musiałek, Filip / Szabra, Dariusz / Wojtas, Jacek

Sensors (Basel, Switzerland)

2024 Band 24, Heft 6

Abstract: This paper presents the description of the wavelength modulation spectroscopy (WMS) experiment, the parameters of which were established by use of the Artificial Intelligence (AI) algorithm. As a result, a significant improvement in the signal power to ... ...

Abstract	This paper presents the description of the wavelength modulation spectroscopy (WMS) experiment, the parameters of which were established by use of the Artificial Intelligence (AI) algorithm. As a result, a significant improvement in the signal power to noise power ratio (SNR) was achieved, ranging from 1.6 to 6.5 times, depending on the harmonic. Typically, optimizing the operation conditions of WMS-based gas sensors is based on long-term simulations, complex mathematical model analysis, and iterative experimental trials. An innovative approach based on a biological-inspired genetic algorithm (GA) and custom-made electronics for laser control is proposed. The experimental setup was equipped with a 31.23 m Heriott multipass cell, software lock-in, and algorithms to control the modulation process of the quantum cascade laser (QCL) operating in the long-wavelength-infrared (LWIR) spectral range. The research results show that the applied evolutionary approach can efficiently and precisely explore a wide range of WMS parameter combinations, enabling researchers to dramatically reduce the time needed to identify optimal settings. It took only 300 s to test approximately 1.39 × 10
Sprache	Englisch
Erscheinungsdatum	2024-03-13
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s24061842
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Ultraviolet Photodetectors: From Photocathodes to Low-Dimensional Solids.

Rogalski, Antoni / Bielecki, Zbigniew / Mikołajczyk, Janusz / Wojtas, Jacek

Sensors (Basel, Switzerland)

2023 Band 23, Heft 9

Abstract: The paper presents the long-term evolution and recent development of ultraviolet photodetectors. First, the general theory of ultraviolet (UV) photodetectors is briefly described. Then the different types of detectors are presented, starting with the ... ...

Abstract	The paper presents the long-term evolution and recent development of ultraviolet photodetectors. First, the general theory of ultraviolet (UV) photodetectors is briefly described. Then the different types of detectors are presented, starting with the older photoemission detectors through photomultipliers and image intensifiers. More attention is paid to silicon and different types of wide band gap semiconductor photodetectors such as AlGaN, SiC-based, and diamond detectors. Additionally, Ga
Sprache	Englisch
Erscheinungsdatum	2023-05-02
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Review
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23094452
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Application of Cavity Enhanced Absorption Spectroscopy to the Detection of Nitric Oxide, Carbonyl Sulphide, and Ethane--Breath Biomarkers of Serious Diseases.

Wojtas, Jacek

Sensors (Basel, Switzerland)

2015 Band 15, Heft 6, Seite(n) 14356–14369

Abstract: The paper presents one of the laser absorption spectroscopy techniques as an effective tool for sensitive analysis of trace gas species in human breath. Characterization of nitric oxide, carbonyl sulphide and ethane, and the selection of their absorption ...

Abstract	The paper presents one of the laser absorption spectroscopy techniques as an effective tool for sensitive analysis of trace gas species in human breath. Characterization of nitric oxide, carbonyl sulphide and ethane, and the selection of their absorption lines are described. Experiments with some biomarkers showed that detection of pathogenic changes at the molecular level is possible using this technique. Thanks to cavity enhanced spectroscopy application, detection limits at the ppb-level and short measurements time (<3 s) were achieved. Absorption lines of reference samples of the selected volatile biomarkers were probed using a distributed feedback quantum cascade laser and a tunable laser system consisting of an optical parametric oscillator and difference frequency generator. Setup using the first source provided a detection limit of 30 ppb for nitric oxide and 250 ppb for carbonyl sulphide. During experiments employing a second laser, detection limits of 0.9 ppb and 0.3 ppb were obtained for carbonyl sulphide and ethane, respectively. The conducted experiments show that this type of diagnosis would significantly increase chances for effective therapy of some diseases. Additionally, it offers non-invasive and real time measurements, high sensitivity and selectivity as well as minimizing discomfort for patients. For that reason, such sensors can be used in screening for early detection of serious diseases.
Mesh-Begriff(e)	Biomarkers/analysis ; Breath Tests/methods ; Ethane/analysis ; Humans ; Limit of Detection ; Nitric Oxide/analysis ; Spectrum Analysis/methods ; Sulfur Oxides/analysis
Chemische Substanzen	Biomarkers ; Sulfur Oxides ; Nitric Oxide (31C4KY9ESH) ; carbonyl sulfide (871UI0ET21) ; Ethane (L99N5N533T)
Sprache	Englisch
Erscheinungsdatum	2015-06-17
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s150614356
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Application of Cavity Enhanced Absorption Spectroscopy to the Detection of Nitric Oxide, Carbonyl Sulphide, and Ethane—Breath Biomarkers of Serious Diseases

Jacek Wojtas

Sensors, Vol 15, Iss 6, Pp 14356-

2015 Band 14369

Abstract	The paper presents one of the laser absorption spectroscopy techniques as an effective tool for sensitive analysis of trace gas species in human breath. Characterization of nitric oxide, carbonyl sulphide and ethane, and the selection of their absorption lines are described. Experiments with some biomarkers showed that detection of pathogenic changes at the molecular level is possible using this technique. Thanks to cavity enhanced spectroscopy application, detection limits at the ppb-level and short measurements time (<3 s) were achieved. Absorption lines of reference samples of the selected volatile biomarkers were probed using a distributed feedback quantum cascade laser and a tunable laser system consisting of an optical parametric oscillator and difference frequency generator. Setup using the first source provided a detection limit of 30 ppb for nitric oxide and 250 ppb for carbonyl sulphide. During experiments employing a second laser, detection limits of 0.9 ppb and 0.3 ppb were obtained for carbonyl sulphide and ethane, respectively. The conducted experiments show that this type of diagnosis would significantly increase chances for effective therapy of some diseases. Additionally, it offers non-invasive and real time measurements, high sensitivity and selectivity as well as minimizing discomfort for patients. For that reason, such sensors can be used in screening for early detection of serious diseases.
Schlagwörter	laser absorption spectroscopy ; cavity enhanced spectroscopy ; CEAS ; gas sensors ; breath analysis ; biomarkers ; nitric oxide ; carbonyl sulphide ; ethane ; QCL ; Technology (General) ; T1-995 ; Technology ; T ; Analytical chemistry ; QD71-142 ; Chemistry ; QD1-999 ; Science ; Q
Sprache	Englisch
Erscheinungsdatum	2015-06-01T00:00:00Z
Verlag	MDPI AG
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: stim2b

Wasilewska, Iga / Gupta, Rishikesh Kumar / Wojtaś, Bartosz / Palchevska, Oksana / Kuźnicki, Jacek

Cells

2020 Band 9, Heft 5

Abstract: In neurons, stromal interaction molecule (STIM) proteins regulate store-operated ... ...

Abstract	In neurons, stromal interaction molecule (STIM) proteins regulate store-operated Ca
Mesh-Begriff(e)	Amino Acid Sequence ; Animals ; Calcium-Binding Proteins/chemistry ; Calcium-Binding Proteins/genetics ; Calcium-Binding Proteins/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Developmental/radiation effects ; Gene Knockout Techniques ; Glutamic Acid/metabolism ; Larva/radiation effects ; Light Signal Transduction/radiation effects ; Mutation/genetics ; Neurons/metabolism ; Phenotype ; Phototaxis/radiation effects ; Seizures/metabolism ; Zebrafish/genetics ; Zebrafish/metabolism ; Zebrafish Proteins/chemistry ; Zebrafish Proteins/genetics ; Zebrafish Proteins/metabolism ; gamma-Aminobutyric Acid/metabolism
Chemische Substanzen	Calcium-Binding Proteins ; Zebrafish Proteins ; stim2b protein, zebrafish ; Glutamic Acid (3KX376GY7L) ; gamma-Aminobutyric Acid (56-12-2)
Sprache	Englisch
Erscheinungsdatum	2020-05-21
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2661518-6
ISSN	2073-4409 ; 2073-4409
ISSN (online)	2073-4409
ISSN	2073-4409
DOI	10.3390/cells9051285
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Ammonia Gas Sensors

Zbigniew Bielecki / Tadeusz Stacewicz / Janusz Smulko / Jacek Wojtas

Applied Sciences, Vol 10, Iss 5111, p

Comparison of Solid-State and Optical Methods

2020 Band 5111

Abstract: High precision and fast measurement of gas concentrations is important for both understanding and monitoring various phenomena, from industrial and environmental to medical and scientific applications. This article deals with the recent progress in ... ...

Abstract	High precision and fast measurement of gas concentrations is important for both understanding and monitoring various phenomena, from industrial and environmental to medical and scientific applications. This article deals with the recent progress in ammonia detection using in-situ solid-state and optical methods. Due to the continuous progress in material engineering and optoelectronic technologies, these methods are among the most perceptive because of their advantages in a specific application. We present the basics of each technique, their performance limits, and the possibility of further development. The practical implementations of representative examples are described in detail. Finally, we present a performance comparison of selected practical application, accumulating data reported over the preceding decade, and conclude from this comparison.
Schlagwörter	ammonia detection ; NH 3 ; MOX sensors ; polymer sensors ; laser absorption spectroscopy ; CRDS ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Thema/Rubrik (Code)	621
Sprache	Englisch
Erscheinungsdatum	2020-07-01T00:00:00Z
Verlag	MDPI AG
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: Changes in Calcium Homeostasis and Gene Expression Implicated in Epilepsy in Hippocampi of Mice Overexpressing

Majewski, Lukasz / Wojtas, Bartosz / Maciąg, Filip / Kuznicki, Jacek

International journal of molecular sciences

2019 Band 20, Heft 22

Abstract: Previously, we showed that the overexpression ... ...

Abstract	Previously, we showed that the overexpression of
Mesh-Begriff(e)	Animals ; CA1 Region, Hippocampal/metabolism ; Calcium/metabolism ; Epilepsy/genetics ; Female ; Gene Expression Regulation ; Hippocampus/metabolism ; Homeostasis ; Humans ; Mice ; Neurogenesis/genetics ; Neurons/metabolism ; ORAI1 Protein/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reproducibility of Results ; Ribonucleoproteins/metabolism ; Ribosomes/metabolism ; Up-Regulation/genetics
Chemische Substanzen	ORAI1 Protein ; RNA, Messenger ; Ribonucleoproteins ; Calcium (SY7Q814VUP)
Sprache	Englisch
Erscheinungsdatum	2019-11-06
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms20225539
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: stim2b Knockout Induces Hyperactivity and Susceptibility to Seizures in Zebrafish Larvae

Iga Wasilewska / Rishikesh Kumar Gupta / Bartosz Wojtaś / Oksana Palchevska / Jacek Kuźnicki

Cells, Vol 9, Iss 1285, p

2020 Band 1285

Abstract: In neurons, stromal interaction molecule (STIM) proteins regulate store-operated Ca 2+ entry (SOCE) and are involved in calcium signaling pathways. However, STIM activity in neurological diseases is unclear and should be clarified by studies that are ... ...

Abstract	In neurons, stromal interaction molecule (STIM) proteins regulate store-operated Ca 2+ entry (SOCE) and are involved in calcium signaling pathways. However, STIM activity in neurological diseases is unclear and should be clarified by studies that are performed in vivo rather than in cultured cells in vitro. The present study investigated the role of neuronal Stim2b protein in zebrafish. We generated stim2b knockout zebrafish, which were fertile and had a regular lifespan. Using various behavioral tests, we found that stim2b −/− zebrafish larvae were hyperactive compared with wild-type fish. The mutants exhibited increases in mobility and thigmotaxis and disruptions of phototaxis. They were also more sensitive to pentylenetetrazol and glutamate treatments. Using lightsheet microscopy, a higher average oscillation frequency and higher average amplitude of neuronal Ca 2+ oscillations were observed in stim2b −/− larvae. RNA sequencing detected upregulation of the annexin 3a and gpr39 genes and downregulation of the rrm2 , neuroguidin , and homer2 genes. The latter gene encodes a protein that is involved in several processes that are involved in Ca 2+ homeostasis in neurons, including metabotropic glutamate receptors. We propose that Stim2b deficiency in neurons dysregulates SOCE and triggers changes in gene expression, thereby causing abnormal behavior, such as hyperactivity and susceptibility to seizures.
Schlagwörter	Stim2b ; zebrafish ; behavior ; in vivo imaging ; calcium ; GCaMP5G ; Biology (General) ; QH301-705.5
Thema/Rubrik (Code)	333
Sprache	Englisch
Erscheinungsdatum	2020-05-01T00:00:00Z
Verlag	MDPI AG
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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