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Artikel ; Online: The importance of leucine-rich α-2 glycoprotein-1 in acute calculus cholecystitis.

Harmantepe, A T / Ozdemir, K / Fırat, N / Dikicier, E / Gönüllü, E / Aka, B U / Ozdin, M / Canturk, A O

European review for medical and pharmacological sciences

2024 Band 28, Heft 9, Seite(n) 3414–3419

Abstract: Objective: The aim of this prospective, single-center cohort study was to analyze serum leucine-rich α-2-glycoprotein-1 (LRG1) expression in patients with acute cholecystitis (AC) and to investigate its variation depending on symptom duration.: ... ...

Abstract	Objective: The aim of this prospective, single-center cohort study was to analyze serum leucine-rich α-2-glycoprotein-1 (LRG1) expression in patients with acute cholecystitis (AC) and to investigate its variation depending on symptom duration. Patients and methods: Participants were divided into patients with AC and a healthy control group. At the time of diagnosis, blood samples were collected, and symptom onset times were questioned. Collected serum LRG1 levels were measured. Results: 30 patients and 30 healthy volunteers were included in the study. LRG1 (p=0.008), white blood cells (WBC) (p<0.001), platelet (p=0.003), neutrophil (p<0.001), lymphocyte (p=0.001), and CRP (p=0.014) were significantly different in AC patients vs. the control group. When the correlations of serum laboratory values with the time of onset of symptoms were compared, LRG1 (p<0.001) was significantly correlated, while no significant correlation was observed in C-reactive protein (CRP) (p=0.572), WBC (p=0.155), and neutrophil (p=0.155). Conclusions: LRG1 expression increases after 24 hours in AC patients. Due to its correlation with symptom duration, we believe it can be helpful for timing cholecystectomy.
Mesh-Begriff(e)	Humans ; Glycoproteins/blood ; Male ; Prospective Studies ; Female ; Cholecystitis, Acute/blood ; Cholecystitis, Acute/diagnosis ; Middle Aged ; Adult ; C-Reactive Protein/metabolism ; C-Reactive Protein/analysis ; Case-Control Studies ; Aged
Chemische Substanzen	LRG1 protein, human
Sprache	Englisch
Erscheinungsdatum	2024-05-20
Erscheinungsland	Italy
Dokumenttyp	Journal Article
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
DOI	10.26355/eurrev_202405_36186
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: A different way to diagnosis acute appendicitis: machine learning.

Harmantepe, Ahmet Tarik / Dikicier, Enis / Gönüllü, Emre / Ozdemir, Kayhan / Kamburoğlu, Muhammet Burak / Yigit, Merve

Polski przeglad chirurgiczny

2024 Band 96, Heft 2, Seite(n) 38–43

Abstract: ... Indroduction: ... Machine learning is a branch of artificial intelligence based on the idea that systems can learn from data, identify patterns, and make decisions with minimal human intervention ... ... Aim: ... Our aim is to predict acute ... ...

Abstract	Indroduction: Machine learning is a branch of artificial intelligence based on the idea that systems can learn from data, identify patterns, and make decisions with minimal human intervention. Aim: Our aim is to predict acute appendicitis, which is the most common indication for emergency surgery, using machine learning algorithms with an easy and inexpensive method. Materials and methods: Patients who were treated surgically with a prediagnosis of acute appendicitis in a single center between 2011 and 2021 were analyzed. Patients with right lower quadrant pain were selected. A total of 189 positive and 156 negative appendectomies were found. Gender and hemogram were used as features. Machine learning algorithms and data analysis were made in Python (3.7) programming language. Results: Negative appendectomies were found in 62% (n = 97) of the women and in 38% (n = 59) of the men. Positive appendectomies were present in 38% (n = 72) of the women and 62% (n = 117) of the men. The accuracy in the test data was 82.7% in logistic regression, 68.9% in support vector machines, 78.1% in k-nearest neighbors, and 83.9% in neural networks. The accuracy in the voting classifier created with logistic regression, k-nearest neighbor, support vector machines, and artificial neural networks was 86.2%. In the voting classifier, the sensitivity was 83.7% and the specificity was 88.6%. Conclusions: The results of our study show that machine learning is an effective method for diagnosing acute appendicitis. This study presents a practical, easy, fast, and inexpensive method to predict the diagnosis of acute appendicitis. .
Mesh-Begriff(e)	Male ; Humans ; Female ; Appendicitis/diagnosis ; Appendicitis/surgery ; Artificial Intelligence ; Machine Learning ; Abdominal Pain ; Acute Disease
Sprache	Englisch
Erscheinungsdatum	2024-04-17
Erscheinungsland	Poland
Dokumenttyp	Journal Article
ZDB-ID	128732-1
ISSN	2299-2847 ; 0032-373X
ISSN (online)	2299-2847
ISSN	0032-373X
DOI	10.5604/01.3001.0053.5994
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Comparison of treatment methods in plastron appendicitis: a tertiary center experience.

Ozdemir, Kayhan / Harmantepe, Ahmet Tarik / Dulger, Ugur Can / Gonullu, Emre / Dikicier, Enis / Bayhan, Zulfu / Altintoprak, Fatih

Malawi medical journal : the journal of Medical Association of Malawi

2024 Band 35, Heft 4, Seite(n) 224–227

Abstract: Background: It is controversial which treatment method is superior in plastron appendicitis and the research is still going on. The aim of this study is to compare treatment methods for plastron appendicitis in the adult population with our experience.!# ...

Abstract	Background: It is controversial which treatment method is superior in plastron appendicitis and the research is still going on. The aim of this study is to compare treatment methods for plastron appendicitis in the adult population with our experience. Materials and methods: The data of 92 patients who were diagnosed with plastron appendicitis in university hospital between 2015 and 2021 were analyzed retrospectively. Data were taken from the hospital database. The patients were divided into three groups: those treated with primary surgery, with interval appendectomy and only with conservative method. Results: Interval appendectomy resulted in a lower rate of conversion to open surgery compared to primary surgery, shorter operative time, and lower complication rates. Surgical procedures were found to be superior in detecting neoplasms compared to conservative treatment. After conservative treatment, one of three patients was retreated with the diagnosis of acute appendicitis. Conclusion: In plastron appendicitis, routine interval appendectomy can be performed due to its advantages over other treatments such as the frequency of attacks after conservative treatment, the risk of the tumor being overlooked in conservative treatment, and the high rate of complications and conversion to open surgery in the primary surgery group.
Mesh-Begriff(e)	Adult ; Humans ; Retrospective Studies ; Appendicitis/surgery ; Appendicitis/complications ; Appendicitis/diagnosis ; Length of Stay ; Appendectomy/adverse effects ; Appendectomy/methods ; Acute Disease ; Treatment Outcome
Sprache	Englisch
Erscheinungsdatum	2024-02-01
Erscheinungsland	Malawi
Dokumenttyp	Journal Article
ISSN	1995-7270 ; 1995-7262
ISSN (online)	1995-7270
ISSN	1995-7262
DOI	10.4314/mmj.v35i4.5
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Radiodensitometric study for evaluation of bone mineral density around dental implants after zoledronic acid treatment in ovariectomized rats.

Dikicier, S / Dikicier, E / Karacayli, U / Erguder, B

Medicina oral, patologia oral y cirugia bucal

2017 Band 22, Heft 3, Seite(n) e377–e382

Abstract: Background: The purpose of this study was to evaluate the effects of intravenous zoledronic acid applied systemically on osseointegration of dental implants and the surrounding bone mineral density (BMD) in the ovariectomized rats.: Material and ... ...

Abstract	Background: The purpose of this study was to evaluate the effects of intravenous zoledronic acid applied systemically on osseointegration of dental implants and the surrounding bone mineral density (BMD) in the ovariectomized rats. Material and methods: 36 rats were divided into three groups: control (CTRL), ovariectomy (OVX), and ovariectomy-zoledronic acid (OVX/ZOL). The rats in the CTRL group underwent sham surgery, while rats in OVX and OVX / ZOL group underwent ovariectomy. After 12 weeks, rats from OVX / ZOL were injected with 0.04 mg/kg ZOL intravenously once a week for 6 weeks. The rats from CTRL and OVX groups were injected with 0.9% NaCl. Implants were placed in the left tibia. After 8 weeks, rats were sacrificed and tibia bones were removed for radiodensitometric examination. Digital radiographs of bones' lateral surface were taken. The BMD was measured by using radiographic analysis software. Results: Statistically significant differences were found between all groups (p<0.05). While highest mean BMD values were observed in the CTRL group, the lowest were in the OVX group. Conclusions: The systemic use of ZOL has increased the bone density around the implants inserted osteoporotic rat tibia.
Sprache	Englisch
Erscheinungsdatum	2017--01
Erscheinungsland	Spain
Dokumenttyp	Journal Article
ZDB-ID	2171573-7
ISSN	1698-6946 ; 1698-4447
ISSN (online)	1698-6946
ISSN	1698-4447
DOI	10.4317/medoral.21706
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Multiple Gastritis Cystica Profunda in a Patient without Gastric Surgery History.

Dikicier, Enis / Altintoprak, Fatih

Archives of Iranian medicine

2018 Band 21, Heft 12, Seite(n) 608–610

Abstract: Gastritis cystica profunda (GCP) is a rare condition characterized by polypoid cystic ectasia of the submucosal layer with cystic dilatation of the glandular structures of the stomach. The probable pathogenesis refers to degradation of the integrity of ... ...

Abstract	Gastritis cystica profunda (GCP) is a rare condition characterized by polypoid cystic ectasia of the submucosal layer with cystic dilatation of the glandular structures of the stomach. The probable pathogenesis refers to degradation of the integrity of the muscularis mucosa and migration of epithelial cells to the submucosal layer. The most common cause known in the literature for this occurrence is previous stomach surgery. A case presented with two GCP lesions in different locations in the stomach without any history of previous surgery.
Mesh-Begriff(e)	Adult ; Cysts/complications ; Cysts/diagnosis ; Cysts/surgery ; Endosonography ; Gastritis/complications ; Gastritis/diagnosis ; Gastritis/diagnostic imaging ; Humans ; Male ; Robotic Surgical Procedures ; Stomach/pathology ; Tomography, X-Ray Computed
Sprache	Englisch
Erscheinungsdatum	2018-12-01
Erscheinungsland	Iran
Dokumenttyp	Case Reports ; Journal Article
ZDB-ID	2204979-4
ISSN	1735-3947 ; 1029-2977
ISSN (online)	1735-3947
ISSN	1029-2977
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Does primer appendagitis epiploica require surgical intervention?

Mantoğlu, Barış / Altıntoprak, Fatih / Akın, Emrah / Fırat, Necattin / Gönüllü, Emre / Dikicier, Enis

Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES

2020 Band 26, Heft 6, Seite(n) 883–886

Abstract: Background: Although primer appendagitis epiploica (PAE) is an acute condition, there is no consensus about a standard first-choice treatment. Different non-surgical and surgical interventions for PAE are available.: Methods: In this study, a total ... ...

Titelübersetzung	Primer appendagitis epiploica da cerrahi müdahale gerektirir mi?
Abstract	Background: Although primer appendagitis epiploica (PAE) is an acute condition, there is no consensus about a standard first-choice treatment. Different non-surgical and surgical interventions for PAE are available. Methods: In this study, a total of 39 patients who were diagnosed as PAE between 2013-2018 were evaluated retrospectively concerning recurrences of the disease, medical intervention, and the requirement of hospitalization. USG and abdominal CT were used as diagnostic tools. Patients were also evaluated for a one-month and long-term follow-up. Results: Of the 39 patients, 29 were male and 10 were female. Recurrence was seen in three patients at the earliest six months. These patients responded to medical treatment. Conclusion: Accurate diagnosis with the help of developing imaging methods has made non-surgical treatment a viable option in the treatment of PAE.
Mesh-Begriff(e)	Acute Disease ; Adult ; Colitis/diagnosis ; Colitis/pathology ; Colitis/therapy ; Digestive System Surgical Procedures ; Female ; Humans ; Male ; Middle Aged ; Recurrence ; Retrospective Studies
Sprache	Englisch
Erscheinungsdatum	2020-12-15
Erscheinungsland	Turkey
Dokumenttyp	Journal Article
ZDB-ID	2253739-9
ISSN	1306-696X
ISSN	1306-696X
DOI	10.14744/tjtes.2020.09693
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Treatment results of small bowel perforations due to unusual causes.

Uzunoglu, Mustafa Yener / Altintoprak, Fatih / Dikicier, Enis / Zengin, Ismail

Pakistan journal of medical sciences

2018 Band 34, Heft 4, Seite(n) 974–979

Abstract: Objectives: Although non-traumatic Small Bowel Perforations (SBPs) are rare, they have high rates of morbidity and mortality in case of late presentation. Aetiological factors vary across different geographical regions. In this paper, SBPs caused by ... ...

Abstract	Objectives: Although non-traumatic Small Bowel Perforations (SBPs) are rare, they have high rates of morbidity and mortality in case of late presentation. Aetiological factors vary across different geographical regions. In this paper, SBPs caused by anything other than trauma and other well-known causes are presented and the current literature is reviewed. Methods: The study was conducted at General Surgery Clinics of two different tertiary university hospitals between January 2008 and September 2016. The authors directly involved in managing the patients. This study was approved by the ethical institutional board and was performed at the Department of General Surgery, School of Medicine, Sakarya University. The medical records of patients retained in both hospitals are electronic. Medical records of subjects who had undergone emergency operations with a prediagnosis of acute abdomen in single center, and were determined to have SBPs due to unusual causes, were investigated retrospectively. Patients with aetiological factors such as trauma, mesenteric vascular disease, internal and external hernias, intra abdominal adhesions, inflammatory bowel diseases, and iatrogenic causes were excluded. Results: In total, 35 patients were evaluated, 20 (57.1%) males and 15 (42.9%) females. The mean age of the cases was 51.6 (18-88) years. Mean time until admission at the hospital was 1.4 days (range 0.25-7 days). The most frequent aetiological factors were various malignancies (10 cases, 28.5%) and perforation of Meckel's diverticulum (8 cases, 22.8%). It was surprising to detect a considerable rate of perforation due to bezoars (6 patients, 17.1%). Conclusions: Post-operative consequences of SBPs due to unusual causes are similar with those related to common, known causes. Factors affecting the clinical course are presentation time and patients' clinical status in admission, not aetiology.
Sprache	Englisch
Erscheinungsdatum	2018-08-22
Erscheinungsland	Pakistan
Dokumenttyp	Journal Article
ZDB-ID	2032827-8
ISSN	1681-715X ; 1682-024X ; 1017-4699
ISSN (online)	1681-715X
ISSN	1682-024X ; 1017-4699
DOI	10.12669/pjms.344.14808
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Giant intra-abdominal cystic lymphangioma.

Altintoprak, Fatih / Uzunoglu, Mustafa Yener / Ozdemir, Kayhan / Dikicier, Enis / Kahyaoglu, Zeynep

The Korean journal of internal medicine

2019 Band 34, Heft 3, Seite(n) 678–679

Mesh-Begriff(e)	Abdominal Neoplasms/diagnostic imaging ; Abdominal Neoplasms/pathology ; Humans ; Lymphangioma, Cystic/diagnostic imaging ; Lymphangioma, Cystic/pathology ; Lymphatic Vessels/pathology ; Magnetic Resonance Imaging ; Male ; Middle Aged
Sprache	Englisch
Erscheinungsdatum	2019-01-07
Erscheinungsland	Korea (South)
Dokumenttyp	Case Reports ; Journal Article
ZDB-ID	639023-7
ISSN	2005-6648 ; 1226-3303
ISSN (online)	2005-6648
ISSN	1226-3303
DOI	10.3904/kjim.2017.029
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Reasons for Undesirable Pregnancy Outcomes among Women with Appendicitis: The Experience of a Tertiary Center.

Mantoglu, Baris / Altintoprak, Fatih / Firat, Necattin / Gonullu, Emre / Dikicier, Enis / Akdeniz, Yesim / Aziret, Mehmet / Erkorkmaz, Unal

Emergency medicine international

2020 Band 2020, Seite(n) 6039862

Abstract: Background: Although laparoscopic appendectomy increases its popularity today, the answer to the question of whether to perform open or laparoscopic appendectomy during pregnancy is appropriate in many studies, and the choice of surgery depends on the ... ...

Abstract	Background: Although laparoscopic appendectomy increases its popularity today, the answer to the question of whether to perform open or laparoscopic appendectomy during pregnancy is appropriate in many studies, and the choice of surgery depends on the surgeon. Herein, we aimed to evaluate the variables that affect undesirable pregnancy outcomes that occur as a result of appendicitis during pregnancy. Methods: Seventy-eight pregnant patients with acute appendicitis who underwent laparoscopic or open technique intervention enrolled in this retrospective study. In addition to the demographic structure of the patients, surgical technique, the number of pregnancies, multiple pregnancy status, surgical pathologies, laboratory values, radiological imaging methods, and length of hospital stay were evaluated. The severity of appendicitis was classified according to the pathology results. The patients were divided into two groups according to the outcomes of their pregnancy. Preterm delivery and abortion involved in the study as a single complication section. Results: The mean age of the pregnant patients was 28.6 ± 5. Of the 78 pregnant women with appendicitis, 47.4% had their first pregnancy, 37.2% had their second pregnancy, and 15.4% had 3 or more pregnancies. The preterm delivery and abortus were 19.5% in the open appendectomy (OA) group and 16.2% in the laparoscopic appendectomy (LA) group. No statistically significant difference was detected in this group in terms of appendicitis pathology triggering preterm delivery or abortion ( Conclusion: Consequently, acute appendicitis may cause serious intra-abdominal infection and inflammation in addition to the complexity of the diagnosis due to the nature of pregnancy, as well as undesired pregnancy outcomes with the surgical technique, or independently with other variables.
Sprache	Englisch
Erscheinungsdatum	2020-09-15
Erscheinungsland	Egypt
Dokumenttyp	Journal Article
ZDB-ID	2596429-X
ISSN	2090-2859 ; 2090-2840
ISSN (online)	2090-2859
ISSN	2090-2840
DOI	10.1155/2020/6039862
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Recurrent intestinal ischemia related to Behçet's Disease.

Yalkın, Ömer / Altıntoprak, Fatih / Dikicier, Enis / Uzunoğlu, Mustafa Yener / Kahyaoğlu, Zeynep

Turkish journal of surgery

2018 , Seite(n) 1–3

Abstract: Behçet's disease is a systemic inflammatory disease that may affect multiple organs. However, intraabdominal complications requiring surgical intervention are rare in the natural course of the disease. A 32-year-old male patient with Behçet's disease who ...

Abstract	Behçet's disease is a systemic inflammatory disease that may affect multiple organs. However, intraabdominal complications requiring surgical intervention are rare in the natural course of the disease. A 32-year-old male patient with Behçet's disease who had been followed for 5 years with a diagnosis of acute abdominal syndrome was operated on twice in 18 days. Intestinal ischemia was identified in different segments of the jejenum during each operation. Recurrent segmental intestinal ischemia within a short time interval is rare, although the gastrointestinal involvement can be seen in the normal course of Behçet's disease.
Sprache	Englisch
Erscheinungsdatum	2018-08-28
Erscheinungsland	Turkey
Dokumenttyp	Journal Article
ISSN	2564-6850
ISSN	2564-6850
DOI	10.5152/turkjsurg.2018.3804
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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