Artikel ; Online: A common variant in 11q23.3 associated with hyperlipidemia is mediated by the binding and regulation of GATA4.
2022 Band 7, Heft 1, Seite(n) 4
Abstract: Large-scale genome-wide associations comprising multiple studies have identified hundreds of genetic loci commonly associated with hyperlipidemia-related phenotypes. However, single large cohort remains necessary in aiming to investigate ethnicity- ... ...
Abstract | Large-scale genome-wide associations comprising multiple studies have identified hundreds of genetic loci commonly associated with hyperlipidemia-related phenotypes. However, single large cohort remains necessary in aiming to investigate ethnicity-specific genetic risks and mechanical insights. A community-based cohort comprising 23,988 samples that included both genotype and biochemical information was assembled for the genome-wide association analysis (GWAS) of hyperlipidemia. The analysis identified fifty genetic variants (P < 5 × 10 |
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Sprache | Englisch |
Erscheinungsdatum | 2022-01-19 |
Erscheinungsland | England |
Dokumenttyp | Journal Article |
ZDB-ID | 2813848-X |
ISSN | 2056-7944 ; 2056-7944 |
ISSN (online) | 2056-7944 |
ISSN | 2056-7944 |
DOI | 10.1038/s41525-021-00279-5 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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