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  1. Artikel ; Online: Osteoporosis treatment: the battle to be won.

    Borges, Joao Lindolfo C

    Archives of endocrinology and metabolism

    2020  Band 64, Heft 4, Seite(n) 327–328

    Mesh-Begriff(e) Humans ; Osteoporosis/drug therapy
    Sprache Englisch
    Erscheinungsdatum 2020-08-12
    Erscheinungsland Brazil
    Dokumenttyp Editorial
    ISSN 2359-4292
    ISSN (online) 2359-4292
    DOI 10.20945/2359-3997000000276
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Osteoporosis treatment

    Joao Lindolfo C Borges

    Archives of Endocrinology and Metabolism, Vol 64, Iss 4, Pp 327-

    the battle to be won

    2020  Band 328

    Schlagwörter Medicine ; R ; Diseases of the endocrine glands. Clinical endocrinology ; RC648-665
    Sprache Englisch
    Erscheinungsdatum 2020-08-01T00:00:00Z
    Verlag Brazilian Society of Endocrinology and Metabolism
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Accelerated fracture healing with teriparatide.

    Borges, João Lindolfo C

    Archives of endocrinology and metabolism

    2015  Band 59, Heft 1, Seite(n) 89

    Mesh-Begriff(e) Bone Density Conservation Agents/therapeutic use ; Female ; Femoral Neck Fractures/drug therapy ; Fracture Healing/drug effects ; Humans ; Osteoporotic Fractures/drug therapy ; Teriparatide/therapeutic use
    Chemische Substanzen Bone Density Conservation Agents ; Teriparatide (10T9CSU89I)
    Sprache Englisch
    Erscheinungsdatum 2015-02
    Erscheinungsland Brazil
    Dokumenttyp Comment ; Letter
    ISSN 2359-4292
    ISSN (online) 2359-4292
    DOI 10.1590/2359-3997000000016
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: The Clinical Utility of Vertebral Fracture Assessment in Predicting Fractures.

    Borges, Joao Lindolfo C / de M Miranda, Isabella Santiago / Lewiecki, E Michael

    Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

    2017  Band 20, Heft 3, Seite(n) 304–308

    Abstract: Vertebral fracture (VF) is the most common type of osteoporotic fracture. VFs are associated with diminished quality of life and high morbidity and mortality. The presence of a VF, especially a recent one, is an important risk factor for developing ... ...

    Abstract Vertebral fracture (VF) is the most common type of osteoporotic fracture. VFs are associated with diminished quality of life and high morbidity and mortality. The presence of a VF, especially a recent one, is an important risk factor for developing another fracture. However, most VFs are not clinically recognized. VF assessment by dual-energy X-ray absorptiometry is a convenient, low-cost, low-radiation, reliable method to identify VFs during bone mineral density measurement. The finding of a previously unrecognized VF may change the diagnostic classification, assessment of fracture risk, and treatment strategies. This paper focuses on the utility of VF assessment in clinical practice.
    Mesh-Begriff(e) Absorptiometry, Photon ; Algorithms ; Arthritis, Rheumatoid/diagnostic imaging ; Female ; Humans ; Male ; Osteoporotic Fractures/diagnostic imaging ; Postmenopause ; Predictive Value of Tests ; Recurrence ; Risk Assessment ; Spinal Fractures/diagnostic imaging
    Sprache Englisch
    Erscheinungsdatum 2017-07
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2040951-5
    ISSN 1094-6950
    ISSN 1094-6950
    DOI 10.1016/j.jocd.2017.06.016
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Complicando o monitoramento da osteoporose: mas não aqui.

    Borges, João Lindolfo C

    Arquivos brasileiros de endocrinologia e metabologia

    2004  Band 48, Heft 2, Seite(n) 221–222

    Titelübersetzung Complicating the monitoring of osteoporosis: but not here.
    Mesh-Begriff(e) Bone Density ; Humans ; Osteoporosis/blood ; Osteoporosis/metabolism ; Parathyroid Hormone/blood ; Seasons ; Vitamin D/blood
    Chemische Substanzen Parathyroid Hormone ; Vitamin D (1406-16-2)
    Sprache Portugiesisch
    Erscheinungsdatum 2004-07-07
    Erscheinungsland Brazil
    Dokumenttyp Editorial
    ZDB-ID 603919-4
    ISSN 1677-9487 ; 0004-2730
    ISSN (online) 1677-9487
    ISSN 0004-2730
    DOI 10.1590/s0004-27302004000200002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Accelerated fracture healing with teriparatide.

    Borges, João Lindolfo C / Freitas, Anderson / Bilezikian, John P

    Arquivos brasileiros de endocrinologia e metabologia

    2013  Band 57, Heft 2, Seite(n) 153–156

    Abstract: Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in ... ...

    Abstract Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in experimental models are associated with increased callus size and mineralization, reduced callus remodeling, and improved mechanical strength. Local and systemic bisphosphonate treatment may improve implant fixation. No negative impact on fracture healing has been observed, even after major surgery or when administered immediately after fracture. For the osteoanabolic agent teriparatide, case reports and a randomized trial have produced mixed results, but they are consistent with a positive impact of teriparatide on fracture healing. Some of the agents currently being developed for osteoporosis, notably sclerostin and DKK1 antibodies have shown a beneficial effect on fracture healing. At this point, therefore, there is no evidence that osteoporosis therapies are detrimental to fracture healing with some promising experimental evidence for positive effects on healing, notably for those agents whose actions are primarily anabolic.
    Mesh-Begriff(e) Aged, 80 and over ; Bone Density ; Bone Density Conservation Agents/therapeutic use ; Female ; Femoral Neck Fractures/drug therapy ; Fracture Healing/drug effects ; Humans ; Osteoporotic Fractures/drug therapy ; Randomized Controlled Trials as Topic ; Teriparatide/therapeutic use ; Treatment Outcome
    Chemische Substanzen Bone Density Conservation Agents ; Teriparatide (10T9CSU89I)
    Sprache Englisch
    Erscheinungsdatum 2013-02-05
    Erscheinungsland Brazil
    Dokumenttyp Case Reports ; Journal Article ; Review
    ZDB-ID 603919-4
    ISSN 1677-9487 ; 0004-2730
    ISSN (online) 1677-9487
    ISSN 0004-2730
    DOI 10.1590/s0004-27302013000200010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.B 264: Hefte anzeigen Standort:
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  7. Artikel ; Online: Accelerated fracture healing with teriparatide

    João Lindolfo C. Borges / Anderson Freitas / John P. Bilezikian

    Arquivos brasileiros de Endocrinologia e Metabologia, Vol 57, Iss 2, Pp 153-

    2013  Band 156

    Abstract: Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in ... ...

    Abstract Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in experimental models are associated with increased callus size and mineralization, reduced callus remodeling, and improved mechanical strength. Local and systemic bisphosphonate treatment may improve implant fixation. No negative impact on fracture healing has been observed, even after major surgery or when administered immediately after fracture. For the osteoanabolic agent teriparatide, case reports and a randomized trial have produced mixed results, but they are consistent with a positive impact of teriparatide on fracture healing. Some of the agents currently being developed for osteoporosis, notably sclerostin and DKK1 antibodies have shown a beneficial effect on fracture healing. At this point, therefore, there is no evidence that osteoporosis therapies are detrimental to fracture healing with some promising experimental evidence for positive effects on healing, notably for those agents whose actions are primarily anabolic.
    Schlagwörter Diseases of the endocrine glands. Clinical endocrinology ; RC648-665 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Sprache Portugiesisch
    Erscheinungsdatum 2013-03-01T00:00:00Z
    Verlag Sociedade Brasileira de Endocrinologia e Metabologia
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Accelerated fracture healing with teriparatide

    João Lindolfo C. Borges / Anderson Freitas / John P. Bilezikian

    Arquivos brasileiros de Endocrinologia e Metabologia, Vol 57, Iss 2, Pp 153-

    2013  Band 156

    Abstract: Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in ... ...

    Abstract Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in experimental models are associated with increased callus size and mineralization, reduced callus remodeling, and improved mechanical strength. Local and systemic bisphosphonate treatment may improve implant fixation. No negative impact on fracture healing has been observed, even after major surgery or when administered immediately after fracture. For the osteoanabolic agent teriparatide, case reports and a randomized trial have produced mixed results, but they are consistent with a positive impact of teriparatide on fracture healing. Some of the agents currently being developed for osteoporosis, notably sclerostin and DKK1 antibodies have shown a beneficial effect on fracture healing. At this point, therefore, there is no evidence that osteoporosis therapies are detrimental to fracture healing with some promising experimental evidence for positive effects on healing, notably for those agents whose actions are primarily anabolic.
    Schlagwörter Diseases of the endocrine glands. Clinical endocrinology ; RC648-665 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R
    Sprache Portugiesisch
    Erscheinungsdatum 2013-03-01T00:00:00Z
    Verlag Sociedade Brasileira de Endocrinologia e Metabologia
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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  9. Artikel ; Online: Accelerated fracture healing with teriparatide Consolidação de fratura acelerada com teriparatida

    João Lindolfo C. Borges / Anderson Freitas / John P. Bilezikian

    Arquivos brasileiros de Endocrinologia e Metabologia, Vol 57, Iss 2, Pp 153-

    2013  Band 156

    Abstract: Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in ... ...

    Abstract Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in experimental models are associated with increased callus size and mineralization, reduced callus remodeling, and improved mechanical strength. Local and systemic bisphosphonate treatment may improve implant fixation. No negative impact on fracture healing has been observed, even after major surgery or when administered immediately after fracture. For the osteoanabolic agent teriparatide, case reports and a randomized trial have produced mixed results, but they are consistent with a positive impact of teriparatide on fracture healing. Some of the agents currently being developed for osteoporosis, notably sclerostin and DKK1 antibodies have shown a beneficial effect on fracture healing. At this point, therefore, there is no evidence that osteoporosis therapies are detrimental to fracture healing with some promising experimental evidence for positive effects on healing, notably for those agents whose actions are primarily anabolic. A consolidação adequada da fratura osteoporótica é essencial para recuperação funcional, morbidade e qualidade de vida. Alguns tratamentos para osteoporose podem afetar os processos associados ao reparo ósseo. Por exemplo, os bisfosfonatos, em modelos experimentais, estão associados com aumento do tamanho do calo e a mineralização, reduzindo o remodelamento do calo e melhorando a força mecânica. Tratamento com bisfosfonato, local ou sistêmico, pode melhorar a fixação de implantes. Não foi observado impacto negativo na consolidação da fratura, mesmo após uma cirurgia maior ou quando administrado imediatamente após a fratura. Relatos e um estudo randomizado com o osteoanabólico teriparatida produziram resultados mistos, mas que são consistentes com o impacto positivo da teriparatida na consolidação da fratura. Algumas das drogas que estão sendo desenvolvidas no momento para osteoporose, como anticorpos para esclerotina e DKK1, têm mostrado efeito benéfico na consolidação da fratura. No estágio atual, portanto, não há evidência de que terapias para osteoporose impeçam a consolidação da fratura, mas existem algumas evidências experimentais promissoras de efeito positivo na consolidação, especialmente daqueles agentes cuja ação é primariamente anabólica.
    Schlagwörter Diseases of the endocrine glands. Clinical endocrinology ; RC648-665 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Sprache Portugiesisch
    Erscheinungsdatum 2013-03-01T00:00:00Z
    Verlag Sociedade Brasileira de Endocrinologia e Metabologia
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Complicando o monitoramento da osteoporose

    João Lindolfo C. Borges

    Arquivos brasileiros de Endocrinologia e Metabologia, Vol 48, Iss 2, Pp 221-

    mas não aqui

    2004  Band 222

    Schlagwörter Diseases of the endocrine glands. Clinical endocrinology ; RC648-665 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Sprache Portugiesisch
    Erscheinungsdatum 2004-04-01T00:00:00Z
    Verlag Sociedade Brasileira de Endocrinologia e Metabologia
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

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