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  1. Artikel ; Online: The Ross-Konno Procedure With or Without Mitral Valve Surgery: A Systematic Review With Individual Data Pooling.

    Dib, Nabil / Ducruet, Thierry / Poirier, Nancy / Khairy, Paul

    World journal for pediatric & congenital heart surgery

    2024  , Seite(n) 21501351241232075

    Abstract: Background: ...

    Abstract Background:
    Sprache Englisch
    Erscheinungsdatum 2024-03-07
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2550261-X
    ISSN 2150-136X ; 2150-1351
    ISSN (online) 2150-136X
    ISSN 2150-1351
    DOI 10.1177/21501351241232075
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Ventricular Fibrillation Is a Sign of Life.

    Dib, Nabil / Martins, Raphael / Flécher, Erwan

    Brazilian journal of cardiovascular surgery

    2023  Band 38, Heft 6, Seite(n) e20210428

    Abstract: Ventricular fibrillation (VF) is a deadly rhythm problem. With asystole, it represents one of the most extreme emergencies that may engage vital prognosis within only few minutes if appropriated treatment is not instituted. It is learned in all medical ... ...

    Abstract Ventricular fibrillation (VF) is a deadly rhythm problem. With asystole, it represents one of the most extreme emergencies that may engage vital prognosis within only few minutes if appropriated treatment is not instituted. It is learned in all medical schools worldwide that VF is not compatible with consciousness and sustained life. Moreover, at 37°C, and without restauration of cardiac flow, VF may be responsible for severe and most often irreversible brain damage after 3 minutes.
    Mesh-Begriff(e) Humans ; Ventricular Fibrillation/therapy ; Arrhythmias, Cardiac ; Heart Arrest/diagnosis ; Heart Arrest/therapy ; Prognosis
    Sprache Englisch
    Erscheinungsdatum 2023-10-06
    Erscheinungsland Brazil
    Dokumenttyp Journal Article
    ZDB-ID 2031026-2
    ISSN 1678-9741 ; 1678-9741
    ISSN (online) 1678-9741
    ISSN 1678-9741
    DOI 10.21470/1678-9741-2021-0428
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Navigating a Career in Innovation.

    Dib, Nabil / DeMaria, Anthony M / King, Spencer B

    Journal of the American College of Cardiology

    2022  Band 79, Heft 3, Seite(n) e141–e142

    Mesh-Begriff(e) Career Choice ; Career Mobility ; Humans
    Sprache Englisch
    Erscheinungsdatum 2022-01-20
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2021.08.077
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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  4. Artikel ; Online: Sharing best practices for educational programs on venture creation and commercialization.

    Eidlisz, Jordan / Hill-Whilton, Zachary / Vizgan, Gabriel / Cobos, Daniel / Chitale, Sadhana / Gillespie, Colleen / Dib, Nabil / Gold-von Simson, Gabrielle

    Nature biotechnology

    2024  Band 42, Heft 4, Seite(n) 675–681

    Sprache Englisch
    Erscheinungsdatum 2024-04-17
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1311932-1
    ISSN 1546-1696 ; 1087-0156
    ISSN (online) 1546-1696
    ISSN 1087-0156
    DOI 10.1038/s41587-024-02199-y
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  5. Artikel ; Online: Long-term outcomes after heart transplantation in adult patients with univentricular versus biventricular congenital heart disease.

    Dib, Nabil / Iserin, Laurence / Varnous, Shaida / Guillemain, Romain / Hascoet, Sebastien / Belli, Emre / Cohen, Sarah

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2024  Band 65, Heft 2

    Abstract: Objectives: Heart transplantation (HT) is the only life-extending therapy in adults with congenital heart disease (CHD) and end-stage heart failure. HT is considered at high risk in complex CHD given the anatomical complexity and past medical history. ... ...

    Abstract Objectives: Heart transplantation (HT) is the only life-extending therapy in adults with congenital heart disease (CHD) and end-stage heart failure. HT is considered at high risk in complex CHD given the anatomical complexity and past medical history. Little is known about long-term outcomes after HT in these patients. We aimed to evaluate early and long-term outcomes after HT in adult patients with univentricular versus biventricular CHD.
    Methods: This multicentre retrospective cohort study included all adult CHD patients who underwent HT between 1988 and 2021 in 3 tertiary centres. Factors associated with early (<30 days) and conditional long-term survival were assessed in the entire cohort.
    Results: Over a mean follow-up of 10.1 ± 7.8 years, 149 patients were included, of whom 55 (36.9%) had univentricular CHD. Sixty-four patients died during follow-up including 47 deaths before discharge from hospital. In multivariable analysis, univentricular physiology and female recipient gender were independently associated with a higher risk of early mortality (odds ratio 2.99; 95% confidence interval [1.33-6.74] and odds ratio 2.76; 95% confidence interval [1.23-6.20], respectively). For patients who survived the early period, conditional long-term survival was excellent for both groups and was not different between 2 groups (P = 0.764).
    Conclusions: Adult CHD patients have a high incidence of overall mortality due to a high rate of early mortality. Univentricular physiology was associated with a significant increased risk of early death compared to biventricular physiology. However, late mortality was excellent and no longer different between the 2 physiologies.
    Mesh-Begriff(e) Adult ; Humans ; Female ; Retrospective Studies ; Heart Transplantation ; Heart Defects, Congenital/surgery ; Patient Discharge ; Incidence ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2024-02-19
    Erscheinungsland Germany
    Dokumenttyp Multicenter Study ; Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezad410
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: The Biomedical Entrepreneurship Skills Development Program (BEEP): Educating a New Generation of Medical Innovators.

    Simson, Gabrielle Gold-von / Dib, Nabil / Cobos, Daniel / Johnson, LeAnn

    Scientia (Bristol, England)

    2022  Band 145, Seite(n) 124–127

    Abstract: Innovative, new technologies are rapidly being introduced into the medical world, as scientists and inventors continually discover solutions to all kinds of health issues. However, comprehensive education in medical product development, business process ... ...

    Abstract Innovative, new technologies are rapidly being introduced into the medical world, as scientists and inventors continually discover solutions to all kinds of health issues. However, comprehensive education in medical product development, business process and strategy is distinctly lacking for science students who aspire to become commercial medical innovators and entrepreneurs. Entrepreneurially minded professionals at the New York University Grossman School of Medicine developed, implemented, and integrated programs to train early scientists in the business side of science to accelerate the pace of commercialisation and encourage individuals to pursue venture creation and entrepreneurship to impact highly relevant healthcare solutions.
    Sprache Englisch
    Erscheinungsdatum 2022-05-19
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2059-898X
    ISSN (online) 2059-898X
    DOI 10.33548/SCIENTIA815
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  7. Artikel: Role and Applications of Experimental Animal Models of Fontan Circulation.

    Jalal, Zakaria / Langouet, Elise / Dib, Nabil / Le-Quellenec, Soazig / Mostefa-Kara, Mansour / Martin, Amandine / Roubertie, François / Thambo, Jean-Benoît

    Journal of clinical medicine

    2024  Band 13, Heft 9

    Abstract: Over the last four decades, the Fontan operation has been the treatment of choice for children born with complex congenital heart diseases and a single-ventricle physiology. However, therapeutic options remain limited and despite ongoing improvements in ... ...

    Abstract Over the last four decades, the Fontan operation has been the treatment of choice for children born with complex congenital heart diseases and a single-ventricle physiology. However, therapeutic options remain limited and despite ongoing improvements in initial surgical repair, patients still experience a multiplicity of cardiovascular complications. The causes for cardiovascular failure are multifactorial and include systemic ventricular dysfunction, pulmonary vascular resistance, atrioventricular valve regurgitation, arrhythmia, development of collaterals, protein-losing enteropathy, hepatic dysfunction, and plastic bronchitis, among others. The mechanisms leading to these late complications remain to be fully elucidated. Experimental animal models have been developed as preclinical steps that enable a better understanding of the underlying pathophysiology. They furthermore play a key role in the evaluation of the efficacy and safety of new medical devices prior to their use in human clinical studies. However, these experimental models have several limitations. In this review, we aim to provide an overview of the evolution and progress of the various types of experimental animal models used in the Fontan procedure published to date in the literature. A special focus is placed on experimental studies performed on animal models of the Fontan procedure with or without mechanical circulatory support as well as a description of their impact in the evolution of the Fontan design. We also highlight the contribution of animal models to our understanding of the pathophysiology and assess forthcoming developments that may improve the contribution of animal models for the testing of new therapeutic solutions.
    Sprache Englisch
    Erscheinungsdatum 2024-04-29
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13092601
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Association of Arterial Blood pH at Cannulation With 1 Year Survival Among Veno-Arterial Extracorporeal Membrane Oxygenation Recipients: The Three Seven Rule.

    Dib, Nabil / Belaroussi, Yaniss / Mansour, Alexandre / Anselmi, Amedeo / Auffret, Vincent / Nesseler, Nicolas / Flécher, Erwan

    ASAIO journal (American Society for Artificial Internal Organs : 1992)

    2023  Band 69, Heft 7, Seite(n) e287–e292

    Abstract: We aimed to describe the clinical outcomes of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) therapy in our institution considering clinical context and pH at cannulation. All patients treated by VA-ECMO during the 2005-2020 period with 1 ... ...

    Abstract We aimed to describe the clinical outcomes of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) therapy in our institution considering clinical context and pH at cannulation. All patients treated by VA-ECMO during the 2005-2020 period with 1 year complete follow-up were included. Our cohort was divided in three groups according to the pH level at cannulation: pH <7 (group 1), pH 7-7.2 (group 2), and pH>7.2 (group 3). Survival was analyzed using Kaplan-Meier method. Association between pH group and survival was estimated using a Cox model. A total of 572 patients were included: 60 patients in group 1, 115 in group 2, and 397 in group 3. Refractory cardiogenic shock (36%) was the main indication. One year survival rates were 13%, 36%, and 43% in groups 1, 2, and 3, respectively ( p < 0.001). Death mainly occurred within the first month. The strong correlation between pH and lactates led to propose a simple "three seven rule": pH <7 and lactate >7 was associated with <7% survival. Veno-arterial extracorporeal membrane oxygenation should be considered with caution in patients with pH <7. Lactates and pH might be important parameters to elaborate a new score to predict survival in this population. The "three seven rule" can be very relevant when facing emergency situations.
    Mesh-Begriff(e) Humans ; Extracorporeal Membrane Oxygenation/adverse effects ; Shock, Cardiogenic ; Catheterization/adverse effects ; Hydrogen-Ion Concentration ; Retrospective Studies
    Sprache Englisch
    Erscheinungsdatum 2023-05-04
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 759982-1
    ISSN 1538-943X ; 0162-1432 ; 1058-2916
    ISSN (online) 1538-943X
    ISSN 0162-1432 ; 1058-2916
    DOI 10.1097/MAT.0000000000001964
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  9. Artikel ; Online: Navigating Arrhythmias in Tetralogy of Fallot Throughout the Lifespan: A Case-based Review.

    Vô, Christophe / Dib, Nabil / Bartoletti, Stefano / Gonzalez, Cecilia M / Mondésert, Blandine / Gagnon, Marie-Hélène / Fournier, Anne / Khairy, Paul

    CJC pediatric and congenital heart disease

    2023  Band 2, Heft 6Part A, Seite(n) 404–413

    Abstract: Arrhythmias are a common complication associated with tetralogy of Fallot (ToF), one of the most prevalent forms of congenital heart disease. As illustrated by this case-based review, various forms of arrhythmias can be encountered across the lifespan of ...

    Abstract Arrhythmias are a common complication associated with tetralogy of Fallot (ToF), one of the most prevalent forms of congenital heart disease. As illustrated by this case-based review, various forms of arrhythmias can be encountered across the lifespan of patients with ToF, from infancy to older adulthood. These include atrioventricular block, junctional ectopic tachycardia, and atrial and ventricular arrhythmias. Arrhythmias have important implications on the health and quality of life of patients with ToF and require treatment by caregivers with dedicated expertise. The choice of pharmacologic and/or interventional therapies to alleviate symptoms, avoid complications, and mitigate risks depends in part on the type, severity, and frequency of the arrhythmia, as well as on the particularities of individual clinical scenarios. Preventing, monitoring for, and managing arrhythmias are an integral component of the care of patients with ToF throughout their lifespan that is critical to optimizing health outcomes.
    Sprache Englisch
    Erscheinungsdatum 2023-09-16
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ISSN 2772-8129
    ISSN (online) 2772-8129
    DOI 10.1016/j.cjcpc.2023.09.006
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  10. Artikel: Joint-preserving surgery for idiopathic bilateral osteonecrosis of the distal tibia: A case report.

    Honeine, Mohamad Omar Y / Ghanem, Wendy M / Otayek, Joeffroy N / Dib, Nabil G / Badra, Mohammad I / Moucharafieh, Ramzi S

    Journal of orthopaedic case reports

    2023  Band 13, Heft 10, Seite(n) 47–52

    Abstract: Introduction: Osteonecrosis (ON) is a serious pathological condition that can affect weight-bearing areas of the lower limbs, including the distal tibia. Although trauma is a common cause of ON, the condition has multiple possible etiologies. ON has ... ...

    Abstract Introduction: Osteonecrosis (ON) is a serious pathological condition that can affect weight-bearing areas of the lower limbs, including the distal tibia. Although trauma is a common cause of ON, the condition has multiple possible etiologies. ON has been associated with a range of factors, including trauma, medication use, alcoholism, and vascular disease. Interruption of blood flow to a particular bone region is the first step in the pathophysiology of ON. Conservative management is typically indicated in the early stages of ON, but joint-preserving procedures may be necessary in cases where conservative treatment fails.
    Case report: This article presents a case of bilateral ON of the distal tibia in a 38-year-old female patient without a history of trauma or identifiable risk factors. The patient was initially managed conservatively but ultimately underwent joint-preserving surgery due to treatment failure.
    Conclusion: Joint-preserving procedures should be considered in cases of early-stage distal tibia ON that do not respond to conservative management to prevent joint collapse. This case highlights the importance of considering ON as a possible diagnosis even in the absence of identifiable risk factors or trauma.
    Sprache Englisch
    Erscheinungsdatum 2023-10-11
    Erscheinungsland India
    Dokumenttyp Case Reports
    ZDB-ID 2658169-3
    ISSN 2250-0685
    ISSN 2250-0685
    DOI 10.13107/jocr.2023.v13.i10.3932
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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