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  1. Buch ; Online ; E-Book: Brain network dysfunction in neuropsychiatric illness

    Diwadkar, Vaibhav A. / B. Eickhoff, Simon

    methods, applications, and implications

    2021  

    Verfasserangabe Vaibhav A. Diwadkar, Simon B. Eickhoff editors
    Schlagwörter Electronic books
    Sprache Englisch
    Umfang 1 Online-Ressource (xvii, 488 Seiten), Illustrationen, Diagramme
    Verlag Springer
    Erscheinungsort Cham
    Erscheinungsland Schweiz
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020943027
    ISBN 978-3-030-59797-9 ; 9783030597962 ; 3-030-59797-0 ; 3030597962
    DOI 10.1007/978-3-030-59797-9
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Buch ; Online ; Dissertation / Habilitation: A Comparative Neuroimaging Investigation into Great Ape Brain Aging

    Vickery, Sam [Verfasser] / Eickhoff, Simon B. [Gutachter] / Caspers, Svenja [Gutachter]

    2024  

    Verfasserangabe Sam Vickery ; Gutachter: Simon B. Eickhoff, Svenja Caspers
    Schlagwörter Tiere (Zoologie) ; Animals (Zoology)
    Thema/Rubrik (Code) sg590
    Sprache Englisch
    Verlag Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Erscheinungsort Düsseldorf
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Datenquelle Digitale Dissertationen im Internet

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  3. Buch ; Online ; Dissertation / Habilitation: Einflüsse von Lebensstil- und State-Faktoren auf die Leistungen im Multitasking im höheren Lebensalter

    Destani, Dalif [Verfasser] / Eickhoff, Simon B. [Gutachter] / Dragano, Nico [Gutachter]

    2024  

    Verfasserangabe Dalif Destani ; Gutachter: Simon B. Eickhoff, Nico Dragano
    Schlagwörter Psychologie ; Psychology
    Thema/Rubrik (Code) sg150
    Sprache Deutsch
    Verlag Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Erscheinungsort Düsseldorf
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Datenquelle Digitale Dissertationen im Internet

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  4. Buch ; Online ; Dissertation / Habilitation: Computerassistierte Differenzierung zwischen Patienten mit idiopathischem Parkinson-Syndrom und gesunden Kontrollprobanden anhand unterschiedlicher MRT-Bildgebungsmodalitäten unter Verwendung von Deep Learning

    Boschenriedter, Christian [Verfasser] / Caspers, Julian [Gutachter] / Eickhoff, Simon B. [Gutachter]

    2024  

    Verfasserangabe Christian Boschenriedter ; Gutachter: Julian Caspers, Simon B. Eickhoff
    Schlagwörter Medizin, Gesundheit ; Medicine, Health
    Thema/Rubrik (Code) sg610
    Sprache Deutsch
    Verlag Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Erscheinungsort Düsseldorf
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Datenquelle Digitale Dissertationen im Internet

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  5. Artikel ; Online: Impact of sample size and regression of tissue-specific signals on effective connectivity within the core default mode network.

    Silchenko, Alexander N / Hoffstaedter, Felix / Eickhoff, Simon B

    Human brain mapping

    2023  Band 44, Heft 17, Seite(n) 5858–5870

    Abstract: Interactions within brain networks are inherently directional, which are inaccessible to classical functional connectivity estimates from resting-state functional magnetic resonance imaging (fMRI) but can be detected using spectral dynamic causal ... ...

    Abstract Interactions within brain networks are inherently directional, which are inaccessible to classical functional connectivity estimates from resting-state functional magnetic resonance imaging (fMRI) but can be detected using spectral dynamic causal modeling (DCM). The sample size and unavoidable presence of nuisance signals during fMRI measurement are the two important factors influencing the stability of group estimates of connectivity parameters. However, most recent studies exploring effective connectivity (EC) have been conducted with small sample sizes and minimally pre-processed datasets. We explore the impact of these two factors by analyzing clean resting-state fMRI data from 330 unrelated subjects from the Human Connectome Project database. We demonstrate that both the stability of the model selection procedures and the inference of connectivity parameters are highly dependent on the sample size. The minimum sample size required for stable DCM is approximately 50, which may explain the variability of the DCM results reported so far. We reveal a stable pattern of EC within the core default mode network computed for large sample sizes and demonstrate that the use of subject-specific thresholded whole-brain masks for tissue-specific signals regression enhances the detection of weak connections.
    Mesh-Begriff(e) Humans ; Sample Size ; Default Mode Network ; Nerve Net/diagnostic imaging ; Brain/diagnostic imaging ; Brain Mapping/methods ; Connectome/methods ; Magnetic Resonance Imaging/methods
    Sprache Englisch
    Erscheinungsdatum 2023-09-15
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 1197207-5
    ISSN 1097-0193 ; 1065-9471
    ISSN (online) 1097-0193
    ISSN 1065-9471
    DOI 10.1002/hbm.26481
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Der vorhersagbare Mensch : Chancen und Risiken der KI-basierten Prädiktion von kognitiven Fähigkeiten, Persönlichkeitsmerkmalen und psychischen Erkrankungen.

    Eickhoff, Simon B / Heinrichs, Bert

    Der Nervenarzt

    2021  Band 92, Heft 11, Seite(n) 1140–1148

    Abstract: New approaches to the use of artificial intelligence (AI) to analyze data from neuroimaging but also passively collected data from so-called wearables, such as smartphones or smartwatches, as well as data that can be extracted from social media and other ...

    Titelübersetzung The predictable human : Possibilities and risks of AI-based prediction of cognitive abilities, personality traits and mental illnesses.
    Abstract New approaches to the use of artificial intelligence (AI) to analyze data from neuroimaging but also passively collected data from so-called wearables, such as smartphones or smartwatches, as well as data that can be extracted from social media and other online activities, already make it possible to predict cognitive abilities, personality traits, and mental illnesses, as well as to reveal acute mental states. In this article, we explain the methodological concepts behind these current developments, illuminate the possibilities and limitations, and address ethical and social aspects arising from the use.
    Mesh-Begriff(e) Artificial Intelligence ; Cognition ; Humans ; Mental Disorders/diagnosis ; Personality ; Social Media
    Sprache Deutsch
    Erscheinungsdatum 2021-10-04
    Erscheinungsland Germany
    Dokumenttyp Journal Article ; Review
    ZDB-ID 123291-5
    ISSN 1433-0407 ; 0028-2804
    ISSN (online) 1433-0407
    ISSN 0028-2804
    DOI 10.1007/s00115-021-01197-8
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Teaching Research Data Management with DataLad: A Multi-year, Multi-domain Effort.

    Szczepanik, Michał / Wagner, Adina S / Heunis, Stephan / Waite, Laura K / Eickhoff, Simon B / Hanke, Michael

    Neuroinformatics

    2024  

    Abstract: Research data management has become an indispensable skill in modern neuroscience. Researchers can benefit from following good practices as well as from having proficiency in using particular software solutions. But as these domain-agnostic skills are ... ...

    Abstract Research data management has become an indispensable skill in modern neuroscience. Researchers can benefit from following good practices as well as from having proficiency in using particular software solutions. But as these domain-agnostic skills are commonly not included in domain-specific graduate education, community efforts increasingly provide early career scientists with opportunities for organised training and materials for self-study. Investing effort in user documentation and interacting with the user base can, in turn, help developers improve quality of their software. In this work, we detail and evaluate our multi-modal teaching approach to research data management in the DataLad ecosystem, both in general and with concrete software use. Spanning an online and printed handbook, a modular course suitable for in-person and virtual teaching, and a flexible collection of research data management tips in a knowledge base, our free and open source collection of training material has made research data management and software training available to various different stakeholders over the past five years.
    Sprache Englisch
    Erscheinungsdatum 2024-05-07
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2111941-7
    ISSN 1559-0089 ; 1539-2791
    ISSN (online) 1559-0089
    ISSN 1539-2791
    DOI 10.1007/s12021-024-09665-7
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Noninvasive brain stimulation in autism: review and outlook for personalized interventions in adult patients.

    Hensel, Lukas / Lüdtke, Jana / Brouzou, Katia O / Eickhoff, Simon B / Kamp, Daniel / Schilbach, Leonhard

    Cerebral cortex (New York, N.Y. : 1991)

    2024  Band 34, Heft 13, Seite(n) 8–18

    Abstract: Noninvasive brain stimulation (NIBS) has been increasingly investigated during the last decade as a treatment option for persons with autism spectrum disorder (ASD). Yet, previous studies did not reach a consensus on a superior treatment protocol or ... ...

    Abstract Noninvasive brain stimulation (NIBS) has been increasingly investigated during the last decade as a treatment option for persons with autism spectrum disorder (ASD). Yet, previous studies did not reach a consensus on a superior treatment protocol or stimulation target. Persons with ASD often suffer from social isolation and high rates of unemployment, arising from difficulties in social interaction. ASD involves multiple neural systems involved in perception, language, and cognition, and the underlying brain networks of these functional domains have been well documented. Aiming to provide an overview of NIBS effects when targeting these neural systems in late adolescent and adult ASD, we conducted a systematic search of the literature starting at 631 non-duplicate publications, leading to six studies corresponding with inclusion and exclusion criteria. We discuss these studies regarding their treatment rationale and the accordingly chosen methodological setup. The results of these studies vary, while methodological advances may allow to explain some of the variability. Based on these insights, we discuss strategies for future clinical trials to personalize the selection of brain stimulation targets taking into account intersubject variability of brain anatomy as well as function.
    Mesh-Begriff(e) Humans ; Adult ; Brain ; Autism Spectrum Disorder/therapy ; Precision Medicine/methods ; Precision Medicine/trends ; Transcranial Magnetic Stimulation/methods ; Autistic Disorder/therapy ; Autistic Disorder/physiopathology ; Autistic Disorder/psychology ; Transcranial Direct Current Stimulation/methods
    Sprache Englisch
    Erscheinungsdatum 2024-05-02
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1077450-6
    ISSN 1460-2199 ; 1047-3211
    ISSN (online) 1460-2199
    ISSN 1047-3211
    DOI 10.1093/cercor/bhae096
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: The effect of task complexity on the neural network for response inhibition: An ALE meta-analysis.

    Aziz-Safaie, Taraneh / Müller, Veronika I / Langner, Robert / Eickhoff, Simon B / Cieslik, Edna C

    Neuroscience and biobehavioral reviews

    2024  Band 158, Seite(n) 105544

    Abstract: Response inhibition is classically investigated using the go/no-go (GNGT) and stop-signal task (SST), which conceptually measure different subprocesses of inhibition. Further, different task versions with varying levels of additional executive control ... ...

    Abstract Response inhibition is classically investigated using the go/no-go (GNGT) and stop-signal task (SST), which conceptually measure different subprocesses of inhibition. Further, different task versions with varying levels of additional executive control demands exist, making it difficult to identify the core neural correlates of response inhibition independent of variations in task complexity. Using neuroimaging meta-analyses, we show that a divergent pattern of regions is consistently involved in the GNGT versus SST, arguing for different mechanisms involved when performing the two tasks. Further, for the GNGT a strong effect of task complexity was found, with regions of the multiple demand network (MDN) consistently involved particularly in the complex GNGT. In contrast, both standard and complex SST recruited the MDN to a similar degree. These results complement behavioral evidence suggesting that inhibitory control becomes automatic after some practice and is performed without input of higher control regions in the classic, standard GNGT, but continues to be implemented in a top-down controlled fashion in the SST.
    Mesh-Begriff(e) Humans ; Brain Mapping/methods ; Magnetic Resonance Imaging/methods ; Executive Function/physiology ; Inhibition, Psychological ; Neural Networks, Computer ; Reaction Time/physiology
    Sprache Englisch
    Erscheinungsdatum 2024-01-12
    Erscheinungsland United States
    Dokumenttyp Meta-Analysis ; Journal Article ; Review
    ZDB-ID 282464-4
    ISSN 1873-7528 ; 0149-7634
    ISSN (online) 1873-7528
    ISSN 0149-7634
    DOI 10.1016/j.neubiorev.2024.105544
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Resting state changes in aging and Parkinson's disease are shaped by underlying neurotransmission - a normative modeling study.

    Kasper, Jan / Caspers, Svenja / Lotter, Leon D / Hoffstaedter, Felix / Eickhoff, Simon B / Dukart, Juergen

    Biological psychiatry. Cognitive neuroscience and neuroimaging

    2024  

    Abstract: Background: Human healthy and pathological aging is linked to a steady decline in brain resting state activity and connectivity measures. The neurophysiological mechanisms underlying these changes remain poorly understood.: Methods: Making use of ... ...

    Abstract Background: Human healthy and pathological aging is linked to a steady decline in brain resting state activity and connectivity measures. The neurophysiological mechanisms underlying these changes remain poorly understood.
    Methods: Making use of recent developments in normative modeling and availability of in vivo maps for various neurochemical systems, we test in the UK Biobank cohort (N=25917) if and how age- and Parkinson's disease related resting state changes in commonly applied local and global activity and connectivity measures co-localize with underlying neurotransmitter systems.
    Results: We find the distributions of several major neurotransmitter systems including serotonergic, dopaminergic, noradrenergic, and glutamatergic neurotransmission to correlate with age-related changes as observed across functional activity and connectivity measures. Co-localization patterns in Parkinson's disease deviate from normative aging trajectories for these, as well as for cholinergic and GABAergic, neurotransmission. The deviation from normal co-localization of brain function and GABAa correlates with disease duration.
    Conclusions: These findings provide new insights into molecular mechanisms underlying age- and Parkinson's related brain functional changes by extending the existing evidence elucidating the vulnerability of specific neurochemical attributes to normal aging and Parkinson's disease. The results particularly indicate that alongside dopamine and serotonin, increased vulnerability of glutamatergic, cholinergic, and GABAergic systems may also contribute to Parkinson's disease-related functional alterations. Combining normative modeling and neurotransmitter mapping may aid future research and drug development through deeper understanding of neurophysiological mechanisms underlying specific clinical conditions.
    Sprache Englisch
    Erscheinungsdatum 2024-04-26
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2879089-3
    ISSN 2451-9030 ; 2451-9022
    ISSN (online) 2451-9030
    ISSN 2451-9022
    DOI 10.1016/j.bpsc.2024.04.010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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