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  1. Artikel ; Online: Inquilinus limosus, an atypical Gram-negative rod from lung transplant recipients and cystic fibrosis patients.

    Farfour, Eric / Corvec, Stéphane / Guillard, Thomas / Revillet, Hélène

    Annales de biologie clinique

    2024  Band 82, Heft 2, Seite(n) 1–2

    Sprache Englisch
    Erscheinungsdatum 2024-04-01
    Erscheinungsland France
    Dokumenttyp Journal Article
    ZDB-ID 418098-7
    ISSN 1950-6112 ; 0003-3898
    ISSN (online) 1950-6112
    ISSN 0003-3898
    DOI 10.1684/abc.2024.1876
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Oligella spp.: A systematic review on an uncommon urinary pathogen.

    Farfour, Eric / Vasse, Marc / Vallée, Alexandre

    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

    2024  

    Abstract: Background: Oligella is an uncommon Gram-negative coccobacillus that was first thought to belong to the urogenital tract. The genus Oligella comprises two species that were recovered from various samples worldwide.: Methods: We perform a systematic ... ...

    Abstract Background: Oligella is an uncommon Gram-negative coccobacillus that was first thought to belong to the urogenital tract. The genus Oligella comprises two species that were recovered from various samples worldwide.
    Methods: We perform a systematic review focusing on Oligella microbiological characteristics, habitat, role in Human microbiome and infection, and antimicrobial susceptibility.
    Results: In humans, Oligella is mainly found as part of the microbiome of individuals with predisposing conditions. Oligella were also associated with invasive infections in patients with underlying diseases. Nevertheless, their prevalence remains to determine. Oligella culture requires up to 48 h on agar media in vitro, while urinary samples are usually incubated for 24 h. Consequently, microbiologists should be prompt to prolong the incubation of agar media when the direct examination showed Gram-negative coccobacilli. Oligella is accurately identified using MALDI-TOF mass spectrometry, but biochemical methods often provided inconsistent results. Specific guidelines for antimicrobial susceptibility testing of Oligella lack but the incubation could require up to 48 h of incubation. In contrast to O. urethralis, which is susceptible to third-generation cephalosporin, O. ureolytica is likely resistant to numerous antimicrobials. Genectic determinants of resistance were identified for beta-lactams and aminoglycosides.
    Conclusion: Oligella is an uncommon pathogen that can be underrecognized. Microbiologists should be prompt to prolong the incubation of agar media plated with urines when the direct examination showed Gram-negative coccobacilli. Carbapenems should probably be given for the empirical treatment.
    Sprache Englisch
    Erscheinungsdatum 2024-04-26
    Erscheinungsland Germany
    Dokumenttyp Journal Article ; Review
    ZDB-ID 603155-9
    ISSN 1435-4373 ; 0934-9723 ; 0722-2211
    ISSN (online) 1435-4373
    ISSN 0934-9723 ; 0722-2211
    DOI 10.1007/s10096-024-04797-9
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  3. Artikel ; Online: Mollicutes-related infections in thoracic surgery including lung and heart transplantation: A systematic review.

    Farfour, Eric / Vasse, Marc / Vallée, Alexandre

    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

    2023  Band 43, Heft 1, Seite(n) 169–180

    Abstract: Background: Urogenital Mollicutes, that is, Mycoplasma hominis and Ureaplasma spp., can colonize the urogenital tract. While urogenital colonization is frequent, infections are rare but should not be missed. Furthermore, extragenital infections are even ...

    Abstract Background: Urogenital Mollicutes, that is, Mycoplasma hominis and Ureaplasma spp., can colonize the urogenital tract. While urogenital colonization is frequent, infections are rare but should not be missed. Furthermore, extragenital infections are even rarer. Over the past years, they have been increasingly documented as a cause of hyperammonemia syndrome (HS) and post-surgical infections. We review the literature on studies focused on post-surgical infections and HS involving urogenital Mollicutes after thoracic surgery including lung (LTR) and heart (HTR) transplantation.
    Methods: A systematic review was performed by searching PubMed/Medline case reports, case series, cohort studies, and clinical trials. Cases of infections and HS by urogenital Mollicutes after HTR and LTR transplantations were reported.
    Results: Overall, urogenital Mollicutes were associated with 15 HS, 31 infections in HTR and LTR, and 18 post-thoracic surgical infections in another context. Post-surgical infections were reported in all contexts. They were mainly due to M hominis, the only species that could cultivate on standard enriched agar forming pinpoint colonies after 3-5 days of incubation. Microbiologists should be prompted to pinpoint colonies even if the examination of Gram-staining is negative. The patients' management required surgical treatment and antimicrobials, almost always tetracyclines and/or fluoroquinolones. Conversely, HS occurred almost exclusively in bilateral LTR and is more likely due to Ureaplasma spp. As Ureaplasma spp. do not cultivate on standard media, the microbiological diagnosis was performed using molecular methods.
    Conclusions: Infections involving urogenital Mollicute should be considered in LTR with HS. The overall rate of mortality is high and might be due in part to delay in etiologic diagnosis. Post-surgical infections were reported in all contexts. The route of contamination with Mollicutes remains unknown in HTR and non-transplant surgery, but evidence of transmission from donors has been documented for LTR.
    Mesh-Begriff(e) Humans ; Thoracic Surgery ; Tenericutes ; Ureaplasma ; Heart Transplantation/adverse effects ; Lung
    Sprache Englisch
    Erscheinungsdatum 2023-10-03
    Erscheinungsland United States
    Dokumenttyp Systematic Review ; Journal Article ; Review
    ZDB-ID 1062522-7
    ISSN 1557-3117 ; 1053-2498
    ISSN (online) 1557-3117
    ISSN 1053-2498
    DOI 10.1016/j.healun.2023.09.023
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Plaques en prairie fauchée.

    Farfour, Eric / Zucman, David

    IDCases

    2021  Band 24, Seite(n) e01080

    Abstract: We report a clinical picture of a mowed meadow pattern of the tongue in a 29-year-old sexually active man who has sex with men. The painful lesions also called "Plaques en prairie fauchée", occur in the context of the discovery of a postive HIV serology. ...

    Abstract We report a clinical picture of a mowed meadow pattern of the tongue in a 29-year-old sexually active man who has sex with men. The painful lesions also called "Plaques en prairie fauchée", occur in the context of the discovery of a postive HIV serology. The diagnosis of secondary syphilis was confirmed by a positive syphilis serology (nontreponemal RPR test title of 64) and a positive
    Sprache Englisch
    Erscheinungsdatum 2021-03-23
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2021.e01080
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Comparison of the Alinity M STI with the GeneXpert CT/NG for the detection of sexually transmitted microorganisms.

    Farfour, Eric / Kitous, Cyril / Zucman, David / Touche, Pauline / Panel, Kewin / Fourn, Erwan / Vasse, Marc

    Diagnostic microbiology and infectious disease

    2024  Band 108, Heft 3, Seite(n) 116179

    Abstract: We assess the performances of the Alinity M STI assay (Abbott Molecular) in comparison to the Xpert CT/NG assay (Cepheid). We first retrospectively used a collection of 70 frozen samples of which 33, 31, and 6 were positives for Chlamydia trachomatis (CT) ...

    Abstract We assess the performances of the Alinity M STI assay (Abbott Molecular) in comparison to the Xpert CT/NG assay (Cepheid). We first retrospectively used a collection of 70 frozen samples of which 33, 31, and 6 were positives for Chlamydia trachomatis (CT), Neisseria gonorrhoea (NG), and both micro-organisms respectively. The Alinity M STI and the Xpert CT/NG results were in accordance for all. The mean difference in cycle threshold values between the Xpert CT/NG and the Alinity M STI were -1.6 and 0.0 for CT and NG respectively. Then 214 fresh samples collected from 121 patients were prospectively tested with both instruments. Anal swabs, throat swabs, vaginal swabs, and urines accounted each for about 25%. Seven (3.2%) samples of which 5 anal swabs, provided inconclusive results with the Alinity M STI. In conclusion, the Alinity M STI is an accurate device for the microbiological diagnosis of NG and CT infections.
    Mesh-Begriff(e) Female ; Humans ; Chlamydia trachomatis/genetics ; Gonorrhea/diagnosis ; Gonorrhea/microbiology ; Retrospective Studies ; Neisseria gonorrhoeae/genetics ; Chlamydia Infections/diagnosis ; Tomography, X-Ray Computed ; Sexually Transmitted Diseases/diagnosis ; Sexually Transmitted Diseases/microbiology ; Trichomonas vaginalis ; Prevalence
    Sprache Englisch
    Erscheinungsdatum 2024-01-04
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 604920-5
    ISSN 1879-0070 ; 0732-8893
    ISSN (online) 1879-0070
    ISSN 0732-8893
    DOI 10.1016/j.diagmicrobio.2024.116179
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Evaluation of Four Fully Integrated Molecular Assays for the Detection of Respiratory Viruses during the Co-Circulation of SARS-CoV-2, Influenza and RSV.

    Farfour, Eric / Yung, Thomas / Baudoin, Robin / Vasse, Marc

    Journal of clinical medicine

    2022  Band 11, Heft 14

    Abstract: ... ...

    Abstract Background
    Sprache Englisch
    Erscheinungsdatum 2022-07-06
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11143942
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  7. Artikel ; Online: Monkeypox virus: A novel sexually transmitted disease? A case report from France.

    Vallée, Alexandre / Farfour, Eric / Zucman, David

    Travel medicine and infectious disease

    2022  Band 49, Seite(n) 102394

    Mesh-Begriff(e) Disease Outbreaks ; France ; Humans ; Monkeypox virus ; Sexually Transmitted Diseases/diagnosis
    Sprache Englisch
    Erscheinungsdatum 2022-06-28
    Erscheinungsland Netherlands
    Dokumenttyp Case Reports ; Letter
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2022.102394
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  8. Artikel ; Online: Reply to comments on "Impact of EUCAST rapid Antimicrobial Susceptibility testing (RAST) on management of Gram-negative bloodstream infection".

    Cardot-Martin, E / Colombier, M A / Limousin, L / Farfour, E / Lesprit, P / Vasse, M

    Infectious diseases now

    2023  Band 53, Heft 2, Seite(n) 104667

    Mesh-Begriff(e) Humans ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Sepsis/drug therapy
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Englisch
    Erscheinungsdatum 2023-02-02
    Erscheinungsland France
    Dokumenttyp Letter ; Comment
    ISSN 2666-9919
    ISSN (online) 2666-9919
    DOI 10.1016/j.idnow.2023.104667
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  9. Artikel: Rarely Encountered Gram-Negative Rods and Lung Transplant Recipients: A Narrative Review.

    Farfour, Eric / Roux, Antoine / Sage, Edouard / Revillet, Hélène / Vasse, Marc / Vallée, Alexandre

    Microorganisms

    2023  Band 11, Heft 6

    Abstract: The respiratory tract of lung transplant recipients (LTR) is likely to be colonized with non-fermentative Gram-negative rods. As a consequence of the improvements in molecular sequencing and taxonomy, an increasing number of bacterial species have been ... ...

    Abstract The respiratory tract of lung transplant recipients (LTR) is likely to be colonized with non-fermentative Gram-negative rods. As a consequence of the improvements in molecular sequencing and taxonomy, an increasing number of bacterial species have been described. We performed a review of the literature of bacterial infections in LTR involving non-fermentative Gram-negative rods with exclusion of
    Sprache Englisch
    Erscheinungsdatum 2023-05-31
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11061468
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  10. Artikel ; Online: Impact of COVID-19 pandemic on blood culture practices and bacteremia epidemiology.

    Farfour, Eric / Clichet, Valentin / Péan de Ponfilly, Gauthier / Carbonnelle, Etienne / Vasse, Marc

    Diagnostic microbiology and infectious disease

    2023  Band 107, Heft 1, Seite(n) 116002

    Abstract: The COVID-19 pandemic has strongly impacted healthcare settings. We assess changes in blood culture practices and results during the COVID-19 era. All blood culture vials processed between January 1, 2017, and December 31, 2020, by 3 clinical ... ...

    Abstract The COVID-19 pandemic has strongly impacted healthcare settings. We assess changes in blood culture practices and results during the COVID-19 era. All blood culture vials processed between January 1, 2017, and December 31, 2020, by 3 clinical laboratories were included. A baseline period from January 1, 2017 to December 31, 2019, was compared to the year 2020. COVID-19 "waves" were defined as follows: "wave 1" from March 16 to May 10, 2020, and "wave 2" from October 29 to December 14, 2020. A mean of 143.5 and 158.6 vials per day were processed in 2019 and 2020 respectively. Up to 300 and 220 vials per day were processed during waves 1 and 2. Among positive vials, a higher rate of contaminant was noticed during wave 1 (55.9% vs 45.0%; P < 0.0001) and interwave (46.0% vs 38.6%; P < 0.0001) in comparison to previous years. The prevalence of contaminants returned to the baseline level during wave 2. Streptococcus pneumonia prevalence fell in 2020 in comparison to the baseline (0.4% vs 1.4%; P < 0.0001). The COVID-19 pandemic was associated with an increase in the number of blood culture vials processed, the rate of contaminants, and a fall in the number of pneumococcal bloodstream infections.
    Mesh-Begriff(e) Humans ; COVID-19/epidemiology ; Blood Culture ; Pandemics ; Bacteremia/epidemiology ; Pneumococcal Infections/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2023-06-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 604920-5
    ISSN 1879-0070 ; 0732-8893
    ISSN (online) 1879-0070
    ISSN 0732-8893
    DOI 10.1016/j.diagmicrobio.2023.116002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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