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Article: Suspended sediment transport patterns in the inner shelf â S. Pedro de Moel (Portugal)

Santos, Ana Isabel / Anabela Oliveira / JosÃ© P. Pinto / MÃ³nica Ribeiro / Nuno Zacarias

Journal of sea research. 2014 Oct., v. 93

2014

Abstract: ... Experimental Zone (offshore S. Pedro Moel â W Portugal) to the shore. ADCP and LISST data were collected ...

Abstract	In order to quantify the physical forcing processes associated to sediment transport in the inner shelf, sequential moorings were placed in the three access cable routes connecting the Renewable Energy Experimental Zone (offshore S. Pedro Moel â W Portugal) to the shore. ADCP and LISST data were collected to quantify and establish suspended sediment transport patterns in two different seasonal conditions: September and December 2011. ADCP relative acoustic backscatter was calibrated using LISST suspended sediment concentration and grain size, allowing the integration of current, sediment and wave data. In most cases suspended sediment signatures in all three mooring sites respond mainly to locally induced wave resuspension. More complex dynamic interplay was found in the central mooring site where different finer and coarser sediment signatures were identified, most likely associated with the effect of the Lis River runoff and upwelling fluxes.
Keywords	acoustics ; data collection ; renewable energy sources ; rivers ; runoff ; sediment transport ; sediments ; suspended sediment ; Portugal
Language	English
Dates of publication	2014-10
Size	p. 47-56.
Publishing place	Elsevier B.V.
Document type	Article
ISSN	1385-1101
DOI	10.1016/j.seares.2014.04.009
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: On the Performance of Secure Sharing of Classified Threat Intelligence between Multiple Entities.

Fernandes, Ricardo / Bugla, Sylwia / Pinto, Pedro / Pinto, António

Sensors (Basel, Switzerland)

2023 Volume 23, Issue 2

Abstract: ... from around 2922 s to around 302 s, when considering a shared index with 100,000 elements. From the security ...

Abstract	The sharing of cyberthreat information within a community or group of entities is possible due to solutions such as the Malware Information Sharing Platform (MISP). However, the MISP was considered limited if its information was deemed as classified or shared only for a given period of time. A solution using searchable encryption techniques that better control the sharing of information was previously proposed by the same authors. This paper describes a prototype implementation for two key functionalities of the previous solution, considering multiple entities sharing information with each other: the symmetric key generation of a sharing group and the functionality to update a shared index. Moreover, these functionalities are evaluated regarding their performance, and enhancements are proposed to improve the performance of the implementation regarding its execution time. As the main result, the duration of the update process was shortened from around 2922 s to around 302 s, when considering a shared index with 100,000 elements. From the security analysis performed, the implementation can be considered secure, thus confirming the secrecy of the exchanged nonces. The limitations of the current implementation are depicted, and future work is pointed out.
MeSH term(s)	Computer Security ; Algorithms ; Confidentiality ; Information Dissemination
Language	English
Publishing date	2023-01-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23020914
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The impact of COVID-19 on memory: Recognition for masked and unmasked faces.

Guerra, Natália / Pinto, Raquel / Mendes, Pedro S / Rodrigues, Pedro F S / Albuquerque, Pedro B

Frontiers in psychology

2022 Volume 13, Page(s) 960941

Abstract: Considering the current state of the worldwide pandemic, it is still common to encounter people wearing face protection masks. Although a safety measure against COVID-19, face masks might be compromising our capacity for face recognition. We conducted an ...

Abstract	Considering the current state of the worldwide pandemic, it is still common to encounter people wearing face protection masks. Although a safety measure against COVID-19, face masks might be compromising our capacity for face recognition. We conducted an online study where 140 participants observed masked and unmasked faces in a within-subjects design and then performed a recognition memory task. The best performance was found when there were no masks either at study and test phase, i.e., at the congruent unmasked condition. The worst performance was found for faces encoded with a mask but tested without it (i.e., masked-unmasked incongruent condition), which can be explained by the disruption in holistic face processing and the violation of the encoding specificity principle. Interestingly, considering the unmasked-masked incongruent condition, performance was probably affected by the violation of the encoding specificity principle but protected by holistic processing that occurred during encoding.
Language	English
Publishing date	2022-10-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.960941
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Role of serum-specific immunoglobulin E in egg allergy: a comprehensive study of Portuguese pediatric patients.

Coelho, Pedro Simão / Santos, Gonçalo Martins Dos / Sangalho, Inês / Rosa, Sónia / Pinto, Paula Leiria

Allergologia et immunopathologia

2024 Volume 52, Issue 3, Page(s) 53–59

Abstract: ... 28 KUA/L; area under the curve [AUC] = 0.917; sensitivity [S] 100%; and specificity [Sp] 92 ... ovomucoid for cooked egg (sIgE > 0.99 KUA/L; AUC = 0.788, 95%; S: 79%; and Sp: 74%), and ovomucoid for baked ... egg (sIgE> 4.63 KUA/L; AUC = 0.870; S: 80%; and Sp: 85%) showing predictive capacities.: Conclusions ...

Abstract	Introduction: Food allergies represent a growing public health concern, particularly among children. This study aims to examine egg allergy in pediatric patients and analyze the value of serum-specific immunoglobulin E (sIgE) levels as predictive biomarkers for oral food challenge (OFC) outcomes. Methods: Retrospective study, involving pediatric patients with suspected IgE-mediated egg allergy, conducted at a tertiary hospital. Results: Data from 176 pediatric patients were analyzed, revealing a higher male prevalence (59.1%). Most cases (40.3%) presented symptoms in the first year of life, predominantly mucocutaneous symptoms (46%). OFC results varied across various forms of egg presentation, with cooked egg being the most frequently tested food. Positive OFCs were observed in 14.6% (n = 36) of cases. The study identified specific egg protein biomarkers for positive OFC, with ovalbumin for raw egg (sIgE > 1.28 KUA/L; area under the curve [AUC] = 0.917; sensitivity [S] 100%; and specificity [Sp] 92%), ovomucoid for cooked egg (sIgE > 0.99 KUA/L; AUC = 0.788, 95%; S: 79%; and Sp: 74%), and ovomucoid for baked egg (sIgE> 4.63 KUA/L; AUC = 0.870; S: 80%; and Sp: 85%) showing predictive capacities. Conclusions: The findings underscore the importance of considering various forms of egg presentation in the diagnosis and management of egg allergy. The findings highlight the valuable discriminatory capacity and provided reliable biomarkers, such as ovalbumin for raw egg and ovomucoid for cooked and baked egg in risk assessment, aiding in predicting OFC outcomes and helping clinicians to make informed decisions in diagnosing and managing egg allergies, thus improving patient care and quality of life.
MeSH term(s)	Humans ; Egg Hypersensitivity/diagnosis ; Egg Hypersensitivity/immunology ; Egg Hypersensitivity/epidemiology ; Egg Hypersensitivity/blood ; Immunoglobulin E/blood ; Immunoglobulin E/immunology ; Male ; Female ; Retrospective Studies ; Child, Preschool ; Child ; Infant ; Portugal/epidemiology ; Allergens/immunology ; Biomarkers/blood ; Adolescent ; Prevalence ; Eggs/adverse effects
Chemical Substances	Immunoglobulin E (37341-29-0) ; Allergens ; Biomarkers
Language	English
Publishing date	2024-05-01
Publishing country	Singapore
Document type	Journal Article
ZDB-ID	193144-1
ISSN	1578-1267 ; 0301-0546
ISSN (online)	1578-1267
ISSN	0301-0546
DOI	10.15586/aei.v52i3.1058
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Evolution of the Quinoline Scaffold for the Treatment of Leishmaniasis: A Structural Perspective.

Silva, Carlos F M / Pinto, Diana C G A / Fernandes, Pedro A / Silva, Artur M S

Pharmaceuticals (Basel, Switzerland)

2024 Volume 17, Issue 3

Abstract: Since the beginning of the XXI century, Leishmaniasis has been integrated into the World Health Organization's list of the 20 neglected tropical diseases, being considered a public health issue in more than 88 countries, especially in the tropics, ... ...

Abstract	Since the beginning of the XXI century, Leishmaniasis has been integrated into the World Health Organization's list of the 20 neglected tropical diseases, being considered a public health issue in more than 88 countries, especially in the tropics, subtropics, and the Mediterranean area. Statistically, this disease presents a world prevalence of 12 million cases worldwide, with this number being expected to increase shortly due to the 350 million people considered at risk and the 2-2.5 million new cases appearing every year. The lack of an appropriate and effective treatment against this disease has intensified the interest of many research groups to pursue the discovery and development of novel treatments in close collaboration with the WHO, which hopes to eradicate it shortly. This paper intends to highlight the quinoline scaffold's potential for developing novel antileishmanial agents and provide a set of structural guidelines to help the research groups in the medicinal chemistry field perform more direct drug discovery and development programs. Thus, this review paper presents a thorough compilation of the most recent advances in the development of new quinoline-based antileishmanial agents, with a particular focus on structure-activity relationship studies that should be considerably useful for the future of the field.
Language	English
Publishing date	2024-02-22
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2193542-7
ISSN	1424-8247
ISSN	1424-8247
DOI	10.3390/ph17030285
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: COVID-19-associated arthritis: an emerging new entity?

Farisogullari, Bayram / Pinto, Ana S / Machado, Pedro M

RMD open

2022 Volume 8, Issue 2

Abstract: The current COVID-19 pandemic raises several clinical challenges. Cases of COVID-19-associated arthritis have been reported, and inconsistently described as either COVID-19 viral arthritis or COVID-19 reactive arthritis. We aimed to review all the ... ...

Abstract	The current COVID-19 pandemic raises several clinical challenges. Cases of COVID-19-associated arthritis have been reported, and inconsistently described as either COVID-19 viral arthritis or COVID-19 reactive arthritis. We aimed to review all the reported cases of 'COVID-19-associated arthritis', which we propose, is a better term to define the entire spectrum of new-onset arthritis believed to be associated with SARS-CoV-2 infection. We performed a systematic literature review using MEDLINE, EMBASE and the Cochrane Database of Systematic Reviews to search for articles published up to 13 December 2021. We included cohort studies, case series and case reports describing patients diagnosed with COVID-19 reactive or viral arthritis by a physician, irrespective of fulfilment of classification criteria. To identify relevant studies, medical subject headings and keywords related to 'COVID-19/SARS-CoV-2 infection' and 'reactive arthritis' were used. Our search retrieved 419 articles, of which 31 were included in the review. A total of 33 cases were reported in these 31 articles, the majority being adults (28/33=85%) with peripheral joint involvement (26/33=79%). Most of the patients responded well to treatment and the disease was self-limiting. These 33 case reports describe a possible causal relationship between exposure to SARS-CoV-2 and the onset of arthritis. However, since these cases were reported during a pandemic, other aetiologies cannot be fully excluded. The exact mechanism through which SARS-CoV-2 might trigger arthritis is not fully understood and robust epidemiological data to support a causal relationship are still lacking.
MeSH term(s)	Adult ; Arthritis, Reactive/epidemiology ; Arthritis, Reactive/etiology ; COVID-19/complications ; Humans ; Pandemics ; SARS-CoV-2 ; Systematic Reviews as Topic
Language	English
Publishing date	2022-09-13
Publishing country	England
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2812592-7
ISSN	2056-5933 ; 2056-5933
ISSN (online)	2056-5933
ISSN	2056-5933
DOI	10.1136/rmdopen-2021-002026
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: COVID-19-associated arthritis

Pedro M Machado / Bayram Farisogullari / Ana S Pinto

RMD Open, Vol 8, Iss

an emerging new entity?

2022 Volume 2

Abstract	The current COVID-19 pandemic raises several clinical challenges. Cases of COVID-19-associated arthritis have been reported, and inconsistently described as either COVID-19 viral arthritis or COVID-19 reactive arthritis. We aimed to review all the reported cases of ‘COVID-19-associated arthritis’, which we propose, is a better term to define the entire spectrum of new-onset arthritis believed to be associated with SARS-CoV-2 infection. We performed a systematic literature review using MEDLINE, EMBASE and the Cochrane Database of Systematic Reviews to search for articles published up to 13 December 2021. We included cohort studies, case series and case reports describing patients diagnosed with COVID-19 reactive or viral arthritis by a physician, irrespective of fulfilment of classification criteria. To identify relevant studies, medical subject headings and keywords related to ‘COVID-19/SARS-CoV-2 infection’ and ‘reactive arthritis’ were used. Our search retrieved 419 articles, of which 31 were included in the review. A total of 33 cases were reported in these 31 articles, the majority being adults (28/33=85%) with peripheral joint involvement (26/33=79%). Most of the patients responded well to treatment and the disease was self-limiting. These 33 case reports describe a possible causal relationship between exposure to SARS-CoV-2 and the onset of arthritis. However, since these cases were reported during a pandemic, other aetiologies cannot be fully excluded. The exact mechanism through which SARS-CoV-2 might trigger arthritis is not fully understood and robust epidemiological data to support a causal relationship are still lacking.
Keywords	Medicine ; R
Subject code	610
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	BMJ Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Author Correction: An interpretable machine learning system for colorectal cancer diagnosis from pathology slides.

Neto, Pedro C / Montezuma, Diana / Oliveira, Sara P / Oliveira, Domingos / Fraga, João / Monteiro, Ana / Monteiro, João / Ribeiro, Liliana / Gonçalves, Sofia / Reinhard, Stefan / Zlobec, Inti / Pinto, Isabel M / Cardoso, Jaime S

NPJ precision oncology

2024 Volume 8, Issue 1, Page(s) 83

Language	English
Publishing date	2024-04-03
Publishing country	England
Document type	Published Erratum
ISSN	2397-768X
ISSN	2397-768X
DOI	10.1038/s41698-024-00581-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Mycorrhizal Colonization of Wheat by Intact Extraradical Mycelium of Mn-Tolerant Native Plants Induces Different Biochemical Mechanisms of Protection.

Faria, Jorge M S / Barrulas, Pedro / Pinto, Ana Paula / Brito, Isabel / Teixeira, Dora Martins

Plants (Basel, Switzerland)

2023 Volume 12, Issue 11

Abstract: Soil with excess Mn induces toxicity and impairs crop growth. However, with the development in the soil of an intact extraradical mycelia (ERM) from arbuscular mycorrhizal fungi (AMF) symbiotic to native Mn-tolerant plants, wheat growth is promoted due ... ...

Abstract	Soil with excess Mn induces toxicity and impairs crop growth. However, with the development in the soil of an intact extraradical mycelia (ERM) from arbuscular mycorrhizal fungi (AMF) symbiotic to native Mn-tolerant plants, wheat growth is promoted due to a stronger AMF colonization and subsequent increased protection against Mn toxicity. To determine the biochemical mechanisms of protection induced by this native ERM under Mn toxicity, wheat grown in soil from previously developed
Language	English
Publishing date	2023-05-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704341-1
ISSN	2223-7747
ISSN	2223-7747
DOI	10.3390/plants12112091
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Retinoic Acid-Mediated Control of Energy Metabolism Is Essential for Lung Branching Morphogenesis.

Fernandes-Silva, Hugo / Alves, Marco G / Garcez, Marcia R / Correia-Pinto, Jorge / Oliveira, Pedro F / Homem, Catarina C F / Moura, Rute S

International journal of molecular sciences

2024 Volume 25, Issue 9

Abstract: Lung branching morphogenesis relies on intricate epithelial-mesenchymal interactions and signaling networks. Still, the interplay between signaling and energy metabolism in shaping embryonic lung development remains unexplored. Retinoic acid (RA) ... ...

Abstract	Lung branching morphogenesis relies on intricate epithelial-mesenchymal interactions and signaling networks. Still, the interplay between signaling and energy metabolism in shaping embryonic lung development remains unexplored. Retinoic acid (RA) signaling influences lung proximal-distal patterning and branching morphogenesis, but its role as a metabolic modulator is unknown. Hence, this study investigates how RA signaling affects the metabolic profile of lung branching. We performed ex vivo lung explant culture of embryonic chicken lungs treated with DMSO, 1 µM RA, or 10 µM BMS493. Extracellular metabolite consumption/production was evaluated by using
MeSH term(s)	Animals ; Tretinoin/metabolism ; Tretinoin/pharmacology ; Lung/metabolism ; Lung/drug effects ; Lung/embryology ; Energy Metabolism/drug effects ; Morphogenesis/drug effects ; Signal Transduction/drug effects ; Chick Embryo ; Cell Proliferation/drug effects ; Mitochondria/metabolism ; Mitochondria/drug effects ; Chickens
Chemical Substances	Tretinoin (5688UTC01R)
Language	English
Publishing date	2024-05-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25095054
Database	MEDical Literature Analysis and Retrieval System OnLINE

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