LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 10 von insgesamt 86

Suchoptionen

  1. Artikel ; Online: Guideline-directed medical therapy in patients with heart failure with preserved ejection fraction and polypharmacy: Do not be afraid.

    Salah, Husam M / Fudim, Marat

    European journal of heart failure

    2024  

    Sprache Englisch
    Erscheinungsdatum 2024-05-07
    Erscheinungsland England
    Dokumenttyp Editorial
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.3283
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  2. Artikel ; Online: Biomarker Assessment of Lymphatic System Remodeling in Acute Heart Failure.

    Salah, Husam M / Alvarez, Paulino

    Journal of cardiac failure

    2023  Band 29, Heft 12, Seite(n) 1639–1641

    Mesh-Begriff(e) Humans ; Heart Failure/diagnosis ; Biomarkers ; Lymphatic System ; Ventricular Remodeling
    Chemische Substanzen Biomarkers
    Sprache Englisch
    Erscheinungsdatum 2023-06-12
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 1281194-4
    ISSN 1532-8414 ; 1071-9164
    ISSN (online) 1532-8414
    ISSN 1071-9164
    DOI 10.1016/j.cardfail.2023.06.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  3. Artikel ; Online: Best time for administration of antihypertensive medications: morning or evening?

    Salah, Husam M / Mehta, Jawahar L

    Lancet (London, England)

    2022  Band 400, Heft 10361, Seite(n) 1383–1385

    Mesh-Begriff(e) Humans ; Antihypertensive Agents/therapeutic use ; Hypertension/drug therapy ; Blood Pressure Monitoring, Ambulatory ; Circadian Rhythm ; Blood Pressure
    Chemische Substanzen Antihypertensive Agents
    Sprache Englisch
    Erscheinungsdatum 2022-10-11
    Erscheinungsland England
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)01900-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  4. Artikel ; Online: Tolerability and safety barriers to sodium-glucose cotransporter 2 inhibitor initiation in heart failure with reduced ejection fraction.

    Salah, Husam M / Fudim, Marat

    European journal of heart failure

    2022  Band 24, Heft 9, Seite(n) 1633–1635

    Mesh-Begriff(e) Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Glucose ; Heart Failure/drug therapy ; Humans ; Sodium ; Stroke Volume ; Ventricular Dysfunction, Left
    Chemische Substanzen Sodium (9NEZ333N27) ; Glucose (IY9XDZ35W2)
    Sprache Englisch
    Erscheinungsdatum 2022-08-02
    Erscheinungsland England
    Dokumenttyp Editorial ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.2633
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  5. Artikel: Sodium-glucose Cotransporter 2 Inhibitors and Nonalcoholic Fatty Liver Disease.

    Salah, Husam M / Fudim, Marat

    Heart failure clinics

    2022  Band 18, Heft 4, Seite(n) 625–634

    Abstract: Nonalcoholic fatty liver disease (NAFLD) is a systemic disorder with cardiovascular manifestations; due to its complex and multifactorial pathophysiological mechanisms, no effective pharmacologic treatment has been identified to date. Sodium-glucose ... ...

    Abstract Nonalcoholic fatty liver disease (NAFLD) is a systemic disorder with cardiovascular manifestations; due to its complex and multifactorial pathophysiological mechanisms, no effective pharmacologic treatment has been identified to date. Sodium-glucose cotransporter 2 (SGLT2) inhibitors have demonstrated potentially favorable effects on NAFLD incidence and progression in preclinical and clinical studies. This review summarizes the evidence from preclinical and human studies supporting the use of SGLT2 inhibitors in NAFLD and proposes several mechanisms that may drive these favorable effects (ie, increasing insulin sensitivity, decreasing intrahepatic fat accumulation and lipotoxicity, decreasing oxidative stress and endoplasmic reticulum (ER) stress, improving autophagy, and inhibiting apoptosis).
    Mesh-Begriff(e) Humans ; Liver ; Non-alcoholic Fatty Liver Disease/drug therapy ; Sodium-Glucose Transporter 2 ; Sodium-Glucose Transporter 2 Inhibitors/pharmacology ; Sodium-Glucose Transporter 2 Inhibitors/therapeutic use
    Chemische Substanzen Sodium-Glucose Transporter 2 ; Sodium-Glucose Transporter 2 Inhibitors
    Sprache Englisch
    Erscheinungsdatum 2022-09-07
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2212019-1
    ISSN 1551-7136
    ISSN 1551-7136
    DOI 10.1016/j.hfc.2022.03.011
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  6. Artikel ; Online: COVID-19 Vaccine and Myocarditis.

    Salah, Husam M / Mehta, Jawahar L

    The American journal of cardiology

    2021  Band 157, Seite(n) 146–148

    Mesh-Begriff(e) COVID-19 Vaccines/adverse effects ; Humans ; Myocarditis/etiology ; Stroke Volume ; Troponin/blood
    Chemische Substanzen COVID-19 Vaccines ; Troponin
    Sprache Englisch
    Erscheinungsdatum 2021-07-12
    Erscheinungsland United States
    Dokumenttyp Letter ; Meta-Analysis ; Review
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2021.07.009
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  7. Artikel ; Online: Role of the Renal Lymphatic System in Heart Failure.

    Salah, Husam M / Biegus, Jan / Fudim, Marat

    Current heart failure reports

    2023  Band 20, Heft 2, Seite(n) 113–120

    Abstract: Purpose of review: The lymphatic system plays a major but overlooked role in maintaining fluid homeostasis. Given the unique fluid homeostasis functions of the kidneys, dysregulation of the renal lymphatic system underlies the development of self- ... ...

    Abstract Purpose of review: The lymphatic system plays a major but overlooked role in maintaining fluid homeostasis. Given the unique fluid homeostasis functions of the kidneys, dysregulation of the renal lymphatic system underlies the development of self-propagating congestive pathomechanisms. In this review, we outline the roles of the renal lymphatic system in heart failure (HF).
    Recent findings: Studies have uncovered several pathomechanisms involving the renal lymphatic system in congestive states, such as impaired interstitial draining by the renal lymphatic system, impaired structure and valves of renal lymphatics, lymphatic-induced increase in renal reabsorption of water and sodium, and development of albuminuria with proteinuria-induced renal lymphangiogenesis. These self-propagating mechanisms result in "renal tamponade" with manifestations of cardiorenal syndrome and inappropriate renal response to diuretics. Dysregulation of the renal lymphatic system is integral to the development and progression of congestion in HF. Targeting renal lymphatics may provide a novel pathway to treat intractable congestion.
    Mesh-Begriff(e) Humans ; Heart Failure ; Kidney ; Cardio-Renal Syndrome ; Lymphatic System ; Diuretics
    Chemische Substanzen Diuretics
    Sprache Englisch
    Erscheinungsdatum 2023-02-27
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2151202-4
    ISSN 1546-9549 ; 1546-9530
    ISSN (online) 1546-9549
    ISSN 1546-9530
    DOI 10.1007/s11897-023-00595-0
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  8. Artikel ; Online: Device Interventions for Heart Failure.

    Salah, Husam M / Fudim, Marat / Burkhoff, Daniel

    JACC. Heart failure

    2023  Band 11, Heft 8 Pt 2, Seite(n) 1039–1054

    Abstract: Despite remarkable advances in drug therapy for heart failure (HF), the residual HF-related morbidity, mortality, and hospitalizations remain substantial across all HF phenotypes, and significant proportions of patients with HF remain symptomatic despite ...

    Abstract Despite remarkable advances in drug therapy for heart failure (HF), the residual HF-related morbidity, mortality, and hospitalizations remain substantial across all HF phenotypes, and significant proportions of patients with HF remain symptomatic despite optimal drug therapy. Driven by these unmet clinical needs, the exponential growth of transcatheter interventions, and a recent shift in the regulatory landscape of device-based therapies, novel device-based interventions have emerged as a potential therapy for various phenotypes of HF. Device-based interventions can overcome some of the limitations of drug therapy (eg, intolerance, nonadherence, inconsistent delivery, and recurrent and long-term cost) and can target some HF-related pathophysiologic pathways more effectively than drug therapy. This paper reviews the current evolving landscape of device-based interventions in HF and highlights critical points related to implementation of these therapies in the current workflow of HF management.
    Mesh-Begriff(e) Humans ; Heart Failure/therapy ; Hospitalization ; Phenotype
    Sprache Englisch
    Erscheinungsdatum 2023-08-22
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2023.07.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  9. Artikel ; Online: Meta-analysis of the Effect of Colchicine on Mortality and Mechanical Ventilation in COVID-19.

    Salah, Husam M / Mehta, Jawahar L

    The American journal of cardiology

    2021  Band 145, Seite(n) 170–172

    Mesh-Begriff(e) COVID-19/mortality ; COVID-19/therapy ; Colchicine/therapeutic use ; Global Health ; Gout Suppressants/therapeutic use ; Humans ; Pandemics ; Respiration, Artificial/methods ; SARS-CoV-2 ; Survival Rate/trends
    Chemische Substanzen Gout Suppressants ; Colchicine (SML2Y3J35T)
    Sprache Englisch
    Erscheinungsdatum 2021-02-19
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Meta-Analysis ; Review
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2021.02.005
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  10. Artikel ; Online: Meta-Analysis of the Effect of Aspirin on Mortality in COVID-19.

    Salah, Husam M / Mehta, Jawahar L

    The American journal of cardiology

    2021  Band 142, Seite(n) 158–159

    Mesh-Begriff(e) Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Aspirin/therapeutic use ; COVID-19/drug therapy ; COVID-19/mortality ; Global Health ; Humans ; Pandemics ; Prognosis ; SARS-CoV-2 ; Survival Rate/trends
    Chemische Substanzen Anti-Inflammatory Agents, Non-Steroidal ; Aspirin (R16CO5Y76E)
    Sprache Englisch
    Erscheinungsdatum 2021-01-06
    Erscheinungsland United States
    Dokumenttyp Letter ; Meta-Analysis
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2020.12.073
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang