LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 10 von insgesamt 2295

Suchoptionen

  1. Artikel ; Online: Determination of antibiotic resistance patterns and genotypes of Escherichia coli isolated from wild birds

    Nejash A. Ahmed / Timur Gulhan

    Microbiome, Vol 12, Iss 1, Pp 1-

    2024  Band 15

    Abstract: Abstract Background Curbing the potential negative impact of antibiotic resistance, one of our era's growing global public health crises, requires regular monitoring of the resistance situations, including the reservoir of resistance genes. Wild birds, a ...

    Abstract Abstract Background Curbing the potential negative impact of antibiotic resistance, one of our era's growing global public health crises, requires regular monitoring of the resistance situations, including the reservoir of resistance genes. Wild birds, a possible bioindicator of antibiotic resistance, have been suggested to play a role in the dissemination of antibiotic-resistant bacteria. Therefore, this study was conducted with the objective of determining the phenotypic and genotypic antibiotic resistance profiles of 100 Escherichia coli isolates of gull and pigeon origin by using the Kirby-Bauer disk diffusion method and PCR. Furthermore, the genetic relationships of the isolates were determined by RAPD-PCR. Results Phenotypic antibiotic susceptibility testing revealed that 63% (63/100) and 29% (29/100) of E. coli isolates were resistant to at least one antibiotic and multidrug-resistant (MDR), respectively. With the exception of cephalothin, to which the E. coli isolates were 100% susceptible, tetracycline (52%), kanamycin (38%), streptomycin (37%), ampicillin (28%), chloramphenicol (21%), trimethoprim/sulfamethoxazole (19%), gentamicin (13%), enrofloxacin (12%) and ciprofloxacin (12%) resistances were detected at varying degrees. Among the investigated resistance genes, tet(B) (66%), tet(A) (63%), aphA1 (48%), sul3 (34%), sul2 (26%), strA/strB (24%) and sul1 (16%) were detected. Regarding the genetic diversity of the isolates, the RAPD-PCR-based dendrograms divided both pigeon and gull isolates into five different clusters based on a 70% similarity threshold. Dendrogram analysis revealed 47–100% similarities among pigeon-origin strains and 40–100% similarities among gull-origin E.coli strains. Conclusions This study revealed that gulls and pigeons carry MDR E. coli isolates, which may pose a risk to animal and human health by contaminating the environment with their feces. However, a large-scale epidemiological study investigating the genetic relationship of the strains from a "one health" point of view is ...
    Schlagwörter Antibiotic resistance ; E. coli ; Gull ; Pigeon ; RAPD-PCR ; Microbial ecology ; QR100-130
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2024-01-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Zusatzmaterialien

    Kategorien

  2. Artikel ; Online: Computationally assisted vibrational spectroscopy of nucleic acid bases. 2. Thymine.

    Katsyuba, Sergey A / Burganov, Timur I

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2024  Band 309, Seite(n) 123832

    Abstract: As in the case of cytosine [Phys. Chem. Chem. Phys. 2023, 25, 24121-24128], Raman and infrared (IR) spectra of aqueous thymine and its N-deuterated derivative, thymine- ... ...

    Abstract As in the case of cytosine [Phys. Chem. Chem. Phys. 2023, 25, 24121-24128], Raman and infrared (IR) spectra of aqueous thymine and its N-deuterated derivative, thymine-d
    Sprache Englisch
    Erscheinungsdatum 2024-01-04
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2023.123832
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  3. Artikel ; Online: Determination of antibiotic resistance patterns and genotypes of Escherichia coli isolated from wild birds.

    Ahmed, Nejash A / Gulhan, Timur

    Microbiome

    2024  Band 12, Heft 1, Seite(n) 8

    Abstract: Background: Curbing the potential negative impact of antibiotic resistance, one of our era's growing global public health crises, requires regular monitoring of the resistance situations, including the reservoir of resistance genes. Wild birds, a ... ...

    Abstract Background: Curbing the potential negative impact of antibiotic resistance, one of our era's growing global public health crises, requires regular monitoring of the resistance situations, including the reservoir of resistance genes. Wild birds, a possible bioindicator of antibiotic resistance, have been suggested to play a role in the dissemination of antibiotic-resistant bacteria. Therefore, this study was conducted with the objective of determining the phenotypic and genotypic antibiotic resistance profiles of 100 Escherichia coli isolates of gull and pigeon origin by using the Kirby-Bauer disk diffusion method and PCR. Furthermore, the genetic relationships of the isolates were determined by RAPD-PCR.
    Results: Phenotypic antibiotic susceptibility testing revealed that 63% (63/100) and 29% (29/100) of E. coli isolates were resistant to at least one antibiotic and multidrug-resistant (MDR), respectively. With the exception of cephalothin, to which the E. coli isolates were 100% susceptible, tetracycline (52%), kanamycin (38%), streptomycin (37%), ampicillin (28%), chloramphenicol (21%), trimethoprim/sulfamethoxazole (19%), gentamicin (13%), enrofloxacin (12%) and ciprofloxacin (12%) resistances were detected at varying degrees. Among the investigated resistance genes, tet(B) (66%), tet(A) (63%), aphA1 (48%), sul3 (34%), sul2 (26%), strA/strB (24%) and sul1 (16%) were detected. Regarding the genetic diversity of the isolates, the RAPD-PCR-based dendrograms divided both pigeon and gull isolates into five different clusters based on a 70% similarity threshold. Dendrogram analysis revealed 47-100% similarities among pigeon-origin strains and 40-100% similarities among gull-origin E.coli strains.
    Conclusions: This study revealed that gulls and pigeons carry MDR E. coli isolates, which may pose a risk to animal and human health by contaminating the environment with their feces. However, a large-scale epidemiological study investigating the genetic relationship of the strains from a "one health" point of view is warranted to determine the possible transmission patterns of antibiotic-resistant bacteria between wild birds, the environment, humans, and other hosts. Video Abstract.
    Mesh-Begriff(e) Animals ; Humans ; Escherichia coli/genetics ; Random Amplified Polymorphic DNA Technique ; Birds ; Genotype ; Anti-Bacterial Agents/pharmacology ; Drug Resistance, Microbial
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Englisch
    Erscheinungsdatum 2024-01-08
    Erscheinungsland England
    Dokumenttyp Video-Audio Media ; Journal Article
    ZDB-ID 2697425-3
    ISSN 2049-2618 ; 2049-2618
    ISSN (online) 2049-2618
    ISSN 2049-2618
    DOI 10.1186/s40168-023-01729-1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  4. Artikel ; Online: Low working memory reduces the use of mental contrasting.

    Timur Sevincer, A / Schröder, Anne / Plakides, Alexander / Edler, Nils / Oettingen, Gabriele

    Consciousness and cognition

    2024  Band 118, Seite(n) 103644

    Abstract: Mentally contrasting a desired future with reality is a self-regulation strategy that helps people effectively pursue important personal wishes. People with higher self-regulation skills are more likely to spontaneously use mental contrasting. Because ... ...

    Abstract Mentally contrasting a desired future with reality is a self-regulation strategy that helps people effectively pursue important personal wishes. People with higher self-regulation skills are more likely to spontaneously use mental contrasting. Because one central cognitive function underlying self-regulation is working memory capacity, we investigated whether people with low rather than high working memory capacity are less likely to spontaneously use mental contrasting. Study 1 provided correlational evidence that participants with lower working memory capacity, as measured by the Operation-Span Task, were less likely to use mental contrasting when elaborating an important interpersonal wish. Study 2 provided experimental evidence that manipulating low working memory capacity by inducing cognitive load (vs. no load) led fewer participants to use mental contrasting. The findings have theoretical implications by illuminating the processes that impede mental contrasting, and they have applied implications for understanding how to foster the use of mental contrasting in everyday life.
    Mesh-Begriff(e) Humans ; Memory, Short-Term/physiology ; Cognition
    Sprache Englisch
    Erscheinungsdatum 2024-01-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1106647-7
    ISSN 1090-2376 ; 1053-8100
    ISSN (online) 1090-2376
    ISSN 1053-8100
    DOI 10.1016/j.concog.2024.103644
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  5. Artikel ; Online: The country’s land potential as a key factor in ensuring its food security

    Papaskiri Timur V. / Lipski Stanislav A.

    BIO Web of Conferences, Vol 82, p

    Land management and legal aspect

    2024  Band 05006

    Abstract: The article analyzes the state of the country’s land resources and land management measures to optimize their use for reliable food security. According to the results of the analysis, a number of problems that arose in the post-reform period were ... ...

    Abstract The article analyzes the state of the country’s land resources and land management measures to optimize their use for reliable food security. According to the results of the analysis, a number of problems that arose in the post-reform period were identified: unclaimed land shares and their allocation to independent consolidated plots, termination of processing of previously developed farmland, lack of proper land management support, including due to imperfect legislation. The prolonged consequences of these processes are still underestimated. The authors point out that land management measures and the need for their implementation are a necessary condition for successfully solving these problems.
    Schlagwörter Microbiology ; QR1-502 ; Physiology ; QP1-981 ; Zoology ; QL1-991
    Sprache Englisch
    Erscheinungsdatum 2024-01-01T00:00:00Z
    Verlag EDP Sciences
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Zusatzmaterialien

    Kategorien

  6. Artikel ; Online: Recovering fluorescence spectra hidden by scattering signal: In search of the best smoother.

    Krylov, Ivan N / Labutin, Timur A

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2023  Band 293, Seite(n) 122441

    Abstract: Interpolation of the scattering areas in fluorescence excitation-emission matrices is a useful preprocessing method in fluorescence spectroscopy and data modelling. Commonly used row-by-row interpolation using piecewise cubic Hermite interpolating ... ...

    Abstract Interpolation of the scattering areas in fluorescence excitation-emission matrices is a useful preprocessing method in fluorescence spectroscopy and data modelling. Commonly used row-by-row interpolation using piecewise cubic Hermite interpolating polynomials smoother (PCHIP), however, frequently leads to artifacts because it does not make any use of the information in the other dimension. We have suggested the way of constructing the penalty matrices for Whittaker smoothing that removed one of the main sources of difference between the axis of multiparametric signal - the grid step size - thus making it possible to reduce the number of parameters to optimize. We have compared Whittaker smoother with various surface interpolation methods, including LOESS, Kriging, multilevel B-spline approximation, and PCHIP for the purpose of data preprocessing before PARAFAC modelling of fluorescence signal on a model dataset. The two leaders by signal reconstruction and reconstruction of PARAFAC loadings are LOESS and Whittaker smoothing; the latter is additionally shown to have fundamentally interpretable parameters, which are easier to optimise for the whole dataset. Moreover, Whittaker keeps the shape of the signal and is resistant to variations in data structure and noise level that is very important in numerous applications. We also tested smoothers performance for Åsmund Rinnan fluorescence dataset and the high performance of Whittaker was proved. We can recommend the Whittaker smoothing as a perfect tool for interpolation of scattering areas in florescence spectra of seawaters with low signal-to-noise ratio.
    Sprache Englisch
    Erscheinungsdatum 2023-02-04
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2023.122441
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  7. Artikel ; Online: Effects of Filler Anisometry on the Mechanical Response of a Magnetoactive Elastomer Cell: A Single-Inclusion Modeling Approach.

    Nadzharyan, Timur A / Kramarenko, Elena Yu

    Polymers

    2023  Band 16, Heft 1

    Abstract: A finite-element model of the mechanical response of a magnetoactive elastomer (MAE) volume element is presented. Unit cells containing a single ferromagnetic inclusion with geometric and magnetic anisotropy are considered. The equilibrium state of the ... ...

    Abstract A finite-element model of the mechanical response of a magnetoactive elastomer (MAE) volume element is presented. Unit cells containing a single ferromagnetic inclusion with geometric and magnetic anisotropy are considered. The equilibrium state of the cell is calculated using the finite-element method and cell energy minimization. The response of the cell to three different excitation modes is studied: inclusion rotation, inclusion translation, and uniaxial cell stress. The influence of the magnetic properties of the filler particles on the equilibrium state of the MAE cell is considered. The dependence of the mechanical response of the cell on the filler concentration and inclusion anisometry is calculated and analyzed. Optimal filler shapes for maximizing the magnetic response of the MAE are discussed.
    Sprache Englisch
    Erscheinungsdatum 2023-12-29
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16010118
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  8. Artikel ; Online: Computational analysis of the vibrational spectra and structure of aqueous cytosine.

    Katsyuba, Sergey A / Burganov, Timur I

    Physical chemistry chemical physics : PCCP

    2023  Band 25, Heft 35, Seite(n) 24121–24128

    Abstract: The recently developed efficient protocol for the explicit quantum mechanical modeling of the structure and IR spectra of liquids and solutions [ ... ...

    Abstract The recently developed efficient protocol for the explicit quantum mechanical modeling of the structure and IR spectra of liquids and solutions [Katsyuba
    Sprache Englisch
    Erscheinungsdatum 2023-09-13
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp03059h
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  9. Artikel ; Online: Implementation of perioperative blood glucose monitoring and insulin infusion protocol can decrease postoperative infection rate in diabetic patients undergoing elective craniotomy: An observational study.

    Kulikov, Alexander / Krovko, Yulia / Zagidullin, Timur / Bilotta, Federico

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    2024  Band 124, Seite(n) 137–141

    Abstract: Background: Severe perioperative hyperglycemia (SH) is a proven risk factor for postoperative complications after craniotomy. To reduce this risk, it has been proposed to implement the standardized clinical protocol for scheduled perioperative blood ... ...

    Abstract Background: Severe perioperative hyperglycemia (SH) is a proven risk factor for postoperative complications after craniotomy. To reduce this risk, it has been proposed to implement the standardized clinical protocol for scheduled perioperative blood glucose concentration (BGC) monitoring. This would be followed by intravenous (IV) insulin infusion to keep BGC below 180 mg/dl in the perioperative period. The aim of this prospective observational study was to assess the impact of this type of protocol on the postoperative infection rate in patients undergoing elective craniotomy.
    Methods: A total of 42 patients were prospectively enrolled in the study. Protocol included scheduled BGC monitoring in the perioperative period and rapid-acting insulin IV infusion when intraoperative SH was detected. The diagnosis of infection (wound, pulmonary, blood stream, urinary tract infection or central nervous system infection) was established according to CDC criteria within the first postoperative week. A previously enrolled group of patients with sporadic BGC monitoring and subcutaneous insulin injections for SH management was used as a control group.
    Results: An infectious complication (i.e., pneumonia) was diagnosed only in one patient (2 %) in the prospective group. In comparison with the control group, a decrease in the risk of postoperative infection was statistically significant with OR = 0.08 [0.009 - 0.72] (p = 0.02). Implementation of the perioperative BGC monitoring and the correction protocol prevented both severe hyperglycemia and hypoglycemia with BGC < 70 mg/dl.
    Conclusion: Scheduled BGC monitoring and the use of low-dose insulin infusion protocol can decrease the postoperative infection rate in patients undergoing elective craniotomy. Future studies are needed to prove the causality of the implementation of such a protocol with an improved outcome.
    Sprache Englisch
    Erscheinungsdatum 2024-05-04
    Erscheinungsland Scotland
    Dokumenttyp Journal Article
    ZDB-ID 1193674-5
    ISSN 1532-2653 ; 0967-5868
    ISSN (online) 1532-2653
    ISSN 0967-5868
    DOI 10.1016/j.jocn.2024.04.031
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  10. Artikel ; Online: ‘The Chapters on Physics’ by Gregory Palamas

    Timur A. Schukin

    Vestnik Volgogradskogo Gosudarstvennogo Universiteta. Seriâ 4. Istoriâ, Regionovedenie, Meždunarodnye Otnošeniâ, Vol 25, Iss 6, Pp 259-

    Historical Context, the Motivation of the Author, Addressee

    2020  Band 273

    Abstract: Introduction. In spite of the fact that major researchers of Gregory Palamas’ theology, Robert Sinkewicz and John Demetracopoulos, offered detailed explanations of when and for what ‘The chapters on physics’ of Gregory Palamas were written, it seems that ...

    Abstract Introduction. In spite of the fact that major researchers of Gregory Palamas’ theology, Robert Sinkewicz and John Demetracopoulos, offered detailed explanations of when and for what ‘The chapters on physics’ of Gregory Palamas were written, it seems that this issue was not finally resolved. Methods. This article, therefore, has two goals. The first is to answer the question why in ‘The chapters on physics’ the polemic against Barlaam and Akindynos, although it occupies a large part of the treatise, is presented as a part of the broader theological and philosophical program of Palamas, and what role does the cosmological part (1–14 chapters) play in the structure of the treatise. In the author’s opinion, such a statement of the question will allow us to understand what Gregory Palamas was guided by when writing the text. The second objective is to offer a social portrait of the addressee of this treatise, delivering some of representatives of the stratum on which the Palamas was oriented. Analysis. In answering the first question, special attention is paid to chapter 81 of the treatise, which, in the author’s opinion, reflects the intent of the entire text, namely, to demonstrate that the logic according to which something indivisible can be thought of as divisible without ceasing to be indivisible, works not only in the case of essence and energy, that is, in theology, but also in cosmology and anthropology. In answering the second question, the focus is on the figure of Matthew Kantakouzenos, who was at the time of writing the treatise in conflict with his father, emperor John VI Kantakouzenos, thereby causing discord in the political party, which at that time was a defender of the ideas of Hesychasm. It was Matthew Kantakouzenos, in the author’s opinion, or the social stratum behind him, who could be the recipients of the treatise. Results. The analysis of the treatise and its historical context shows that it was written largely for political reasons as a program text of Hesychasm, equipped with natural ...
    Schlagwörter gregory palamas ; hesychasm ; essence and energy ; cosmology ; anthropology ; matthew kantakouzenos ; nicholas kabasilas ; nicephorus gregoras ; History of Russia. Soviet Union. Former Soviet Republics ; DK1-4735 ; International relations ; JZ2-6530
    Thema/Rubrik (Code) 230
    Sprache Russisch
    Erscheinungsdatum 2020-12-01T00:00:00Z
    Verlag Volgograd State University
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang