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  1. AU=Bongaerts Dion AU=Bongaerts Dion
  2. AU=Assari Shervin
  3. AU="Søes, Lillian Marie"
  4. AU="DeForest Hauser, Cindy"
  5. AU=Khosravi Fatemeh
  6. AU="Sandramara Sasso"
  7. AU="Krejci, Ivo"
  8. AU="Kristie Bloom"
  9. AU="Oliveira, Cláudia Regina G C M de"
  10. AU="Giuseppe Di Capua"
  11. AU=Leng Shuguang
  12. AU="Ahmed Y. Abdelbadee"
  13. AU=Berthold F
  14. AU="Virginia M.Y. Lee"
  15. AU="López-Lago, Ana M"
  16. AU="Barkley, Russell A"
  17. AU="Gahwai, Dharmendra"
  18. AU="Nardelli, S."
  19. AU="Clark, Sarah Elizabeth"
  20. AU="Thaísa X. Silva"

Suchergebnis

Treffer 1 - 10 von insgesamt 13

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  1. Artikel ; Online: Closed for business: The mortality impact of business closures during the Covid-19 pandemic.

    Bongaerts, Dion / Mazzola, Francesco / Wagner, Wolf

    PloS one

    2021  Band 16, Heft 5, Seite(n) e0251373

    Abstract: We investigate the effectiveness of business shutdowns to contain the Covid-19 disease. In March 2020, Italy shut down operations in selected sectors of its economy. Using a difference-in-differences approach, we find that municipalities with higher ... ...

    Abstract We investigate the effectiveness of business shutdowns to contain the Covid-19 disease. In March 2020, Italy shut down operations in selected sectors of its economy. Using a difference-in-differences approach, we find that municipalities with higher exposure to closed sectors experienced subsequently lower mortality rates. The implied life savings exceed 9,400 people over a period of less than a month. We also find that business closures exhibited rapidly diminishing returns and had large effects outside the closed businesses themselves, including spillovers to other municipalities. Overall, the results suggest business shutdowns are effective, but should be selectively implemented and centrally coordinated.
    Mesh-Begriff(e) COVID-19/epidemiology ; COVID-19/mortality ; COVID-19/prevention & control ; COVID-19/virology ; Commerce ; Humans ; Italy/epidemiology ; Mortality/trends ; Pandemics/prevention & control ; Quarantine/methods ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2021-05-14
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0251373
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Closed for business

    Dion Bongaerts / Francesco Mazzola / Wolf Wagner

    PLoS ONE, Vol 16, Iss 5, p e

    The mortality impact of business closures during the Covid-19 pandemic.

    2021  Band 0251373

    Abstract: We investigate the effectiveness of business shutdowns to contain the Covid-19 disease. In March 2020, Italy shut down operations in selected sectors of its economy. Using a difference-in-differences approach, we find that municipalities with higher ... ...

    Abstract We investigate the effectiveness of business shutdowns to contain the Covid-19 disease. In March 2020, Italy shut down operations in selected sectors of its economy. Using a difference-in-differences approach, we find that municipalities with higher exposure to closed sectors experienced subsequently lower mortality rates. The implied life savings exceed 9,400 people over a period of less than a month. We also find that business closures exhibited rapidly diminishing returns and had large effects outside the closed businesses themselves, including spillovers to other municipalities. Overall, the results suggest business shutdowns are effective, but should be selectively implemented and centrally coordinated.
    Schlagwörter Medicine ; R ; Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Buch ; Online: Alternatives for issuer-paid credit rating agencies

    Bongaerts, Dion

    (Working paper series / European Central Bank ; 1703)

    2014  

    Verfasserangabe Dion Bongaerts
    Serientitel Working paper series / European Central Bank ; 1703
    Sprache Englisch
    Umfang Online-Ressource (48 S.)
    Verlag European Central Bank
    Erscheinungsort Frankfurt am Main
    Dokumenttyp Buch ; Online
    ISBN 9789289911115 ; 9289911115
    Datenquelle ECONomics Information System

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  4. Buch ; Online: Green certificates

    Bongaerts, Dion / Schoenmaker, Dirk

    A better version of green bonds

    2020  

    Abstract: The market for green bonds is growing rapidly and has been boosted by the European Commission's plan to raise through green bonds 30 percent of the up to €750 billion that will be borrowed under the Next Generation EU coronavirus economic recovery ... ...

    Abstract -The market for green bonds is growing rapidly and has been boosted by the European Commission's plan to raise through green bonds 30 percent of the up to €750 billion that will be borrowed under the Next Generation EU coronavirus economic recovery programme. But while green bonds can reduce the financing costs of green projects and technologies, their current design means they fall short of fulfilling their full potential. Issuing green bonds alongside regular bonds fragments bond issues, reducing liquidity and thus increasing financing costs. Moreover, green bond prices reflect liquidity, credit risk and environmental performance jointly, which makes it difficult to isolate the part of the return on the bonds that relates to environmental performance. -We propose an alternative: issuance of regular bonds with attached green certificates that ensure earmarking for green purposes. The new design would lead to more liquid securities (as only regular bonds are issued), which would reduce financing costs and in turn would provide incentives to start a greater number of environmentally-friendly projects. The new design would also make market prices more informative about environmental performance. In addition, green certificates would address the criticism that green bonds are used mostly for refinancing existing green projects rather than for new projects. -Sovereigns are among the largest issuers of bonds and are therefore natural candidates for implementation of green certificates. The European Commission could also issue regular bonds and green certificates to finance the European Union's recovery package, and should include green certificates in the under-preparation EU Green Bond standard. Commission issuance of green certificates would give a major boost to EU bonds as liquid safe assets while promoting green investment.
    Schlagwörter ddc:330
    Thema/Rubrik (Code) 710
    Sprache Englisch
    Verlag Brussels: Bruegel
    Erscheinungsland de
    Dokumenttyp Buch ; Online
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  5. Artikel: An asset pricing approach to liquidity effects in corporate bond markets

    Bongaerts, Dion / Driessen, Joost / Jong, Frank de

    The review of financial studies Vol. 30, No. 4 , p. 1229-1269

    2017  Band 30, Heft 4, Seite(n) 1229–1269

    Verfasserangabe Dion Bongaerts, Frank de Jong, Joost Driessen
    Schlagwörter Unternehmensanleihe ; CAPM ; Liquidität ; Risiko ; Transaktionskosten ; Risikoprämie ; USA
    Sprache Englisch
    Verlag Oxford Univ. Press
    Erscheinungsort Cary, NC
    Dokumenttyp Artikel
    ZDB-ID 1043666-2 ; 1467494-4
    ISSN 1465-7368 ; 0893-9454
    ISSN (online) 1465-7368
    ISSN 0893-9454
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  6. Artikel ; Online: Uveal Melanoma Patients Have a Distinct Metabolic Phenotype in Peripheral Blood.

    de Bruyn, Daniël P / Bongaerts, Michiel / Bonte, Ramon / Vaarwater, Jolanda / Meester-Smoor, Magda A / Verdijk, Robert M / Paridaens, Dion / Naus, Nicole C / de Klein, Annelies / Ruijter, George J G / Kiliç, Emine / Brosens, Erwin

    International journal of molecular sciences

    2023  Band 24, Heft 6

    Abstract: Uveal melanomas (UM) are detected earlier. Consequently, tumors are smaller, allowing for novel eye-preserving treatments. This reduces tumor tissue available for genomic profiling. Additionally, these small tumors can be hard to differentiate from nevi, ...

    Abstract Uveal melanomas (UM) are detected earlier. Consequently, tumors are smaller, allowing for novel eye-preserving treatments. This reduces tumor tissue available for genomic profiling. Additionally, these small tumors can be hard to differentiate from nevi, creating the need for minimally invasive detection and prognostication. Metabolites show promise as minimally invasive detection by resembling the biological phenotype. In this pilot study, we determined metabolite patterns in the peripheral blood of UM patients (n = 113) and controls (n = 46) using untargeted metabolomics. Using a random forest classifier (RFC) and leave-one-out cross-validation, we confirmed discriminatory metabolite patterns in UM patients compared to controls with an area under the curve of the receiver operating characteristic of 0.99 in both positive and negative ion modes. The RFC and leave-one-out cross-validation did not reveal discriminatory metabolite patterns in high-risk versus low-risk of metastasizing in UM patients. Ten-time repeated analyses of the RFC and LOOCV using 50% randomly distributed samples showed similar results for UM patients versus controls and prognostic groups. Pathway analysis using annotated metabolites indicated dysregulation of several processes associated with malignancies. Consequently, minimally invasive metabolomics could potentially allow for screening as it distinguishes metabolite patterns that are putatively associated with oncogenic processes in the peripheral blood plasma of UM patients from controls at the time of diagnosis.
    Mesh-Begriff(e) Humans ; Pilot Projects ; Melanoma/genetics ; Uveal Neoplasms/diagnosis ; Uveal Neoplasms/genetics ; Phenotype
    Sprache Englisch
    Erscheinungsdatum 2023-03-07
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24065077
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Uveal Melanoma Patients Have a Distinct Metabolic Phenotype in Peripheral Blood

    Daniël P. de Bruyn / Michiel Bongaerts / Ramon Bonte / Jolanda Vaarwater / Magda A. Meester-Smoor / Robert M. Verdijk / Dion Paridaens / Nicole C. Naus / Annelies de Klein / George J. G. Ruijter / Emine Kiliç / Erwin Brosens

    International Journal of Molecular Sciences, Vol 24, Iss 5077, p

    2023  Band 5077

    Abstract: Uveal melanomas (UM) are detected earlier. Consequently, tumors are smaller, allowing for novel eye-preserving treatments. This reduces tumor tissue available for genomic profiling. Additionally, these small tumors can be hard to differentiate from nevi, ...

    Abstract Uveal melanomas (UM) are detected earlier. Consequently, tumors are smaller, allowing for novel eye-preserving treatments. This reduces tumor tissue available for genomic profiling. Additionally, these small tumors can be hard to differentiate from nevi, creating the need for minimally invasive detection and prognostication. Metabolites show promise as minimally invasive detection by resembling the biological phenotype. In this pilot study, we determined metabolite patterns in the peripheral blood of UM patients (n = 113) and controls (n = 46) using untargeted metabolomics. Using a random forest classifier (RFC) and leave-one-out cross-validation, we confirmed discriminatory metabolite patterns in UM patients compared to controls with an area under the curve of the receiver operating characteristic of 0.99 in both positive and negative ion modes. The RFC and leave-one-out cross-validation did not reveal discriminatory metabolite patterns in high-risk versus low-risk of metastasizing in UM patients. Ten-time repeated analyses of the RFC and LOOCV using 50% randomly distributed samples showed similar results for UM patients versus controls and prognostic groups. Pathway analysis using annotated metabolites indicated dysregulation of several processes associated with malignancies. Consequently, minimally invasive metabolomics could potentially allow for screening as it distinguishes metabolite patterns that are putatively associated with oncogenic processes in the peripheral blood plasma of UM patients from controls at the time of diagnosis.
    Schlagwörter noninvasive ; prognostication ; biomarker ; metabolomics ; liquid biopsy ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2023-03-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Buch ; Online: Private Equity and Regulatory Capital

    Bongaerts, Dion / Charlier, Erwin

    (Discussion Paper / CentER for Economic Research ; 2008,52)

    2008  

    Verfasserangabe by By Dion Bongaerts, Erwin Charlier
    Serientitel Discussion Paper / CentER for Economic Research ; 2008,52
    Schlagwörter Private Equity ; Kapitalbedarf ; Basler Akkord ; Portfolio-Management ; Anlageverhalten ; Optionspreistheorie ; Theorie
    Sprache Englisch
    Umfang Online-Ressource (PDF-Datei: 34 S.), graph. Darst.
    Verlag Center for Economic Research
    Erscheinungsort Tilburg
    Dokumenttyp Buch ; Online
    Anmerkung IMD-Felder maschinell generiert
    Datenquelle ECONomics Information System

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  9. Artikel: Private equity and regulatory capital

    Bongaerts, Dion / Charlier, Erwin

    Journal of banking & finance Vol. 33, No. 7 , p. 1211-1220

    2009  Band 33, Heft 7, Seite(n) 1211–1220

    Verfasserangabe Dion Bongaerts; Erwin Charlier
    Schlagwörter Private Equity ; Kapitalbedarf ; Basler Akkord ; Portfolio-Management ; Anlageverhalten ; Optionspreistheorie ; Risikomanagement ; Theorie
    Sprache Englisch
    Umfang graph. Darst.
    Verlag Elsevier
    Erscheinungsort Amsterdam [u.a.]
    Dokumenttyp Artikel
    ZDB-ID 752905-3 ; 1460614-8
    ISSN 1872-6372 ; 0378-4266
    ISSN (online) 1872-6372
    ISSN 0378-4266
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  10. Buch: Multiple ratings and credit spreads

    Bongaerts, Dion / Cremers, Martijn K. J / Goetzmann, William N

    (NBER working paper series ; 15331)

    2009  

    Verfasserangabe Dion Bongaerts; K. J. Martijn Cremers; William N. Goetzmann
    Serientitel NBER working paper series ; 15331
    Schlagwörter Unternehmensanleihe ; Kreditwürdigkeit ; Ratingagentur ; Informationswert ; USA
    Sprache Englisch
    Umfang 44 S., graph. Darst.
    Erscheinungsort Cambridge, Mass
    Dokumenttyp Buch
    Datenquelle ECONomics Information System

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