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  1. AU="Savino, Wilson" AU="Savino, Wilson"
  2. AU="Jin Han Nam"
  3. AU="Millburn, Michael V"
  4. AU="Ciebiera, Małgorzata"
  5. AU="Granich, R"
  6. AU="Koh, Lian Chye Winston"
  7. AU="Meredith M. White"
  8. AU="Aft, Rebecca"
  9. AU="Urban, Gerald A"
  10. AU="Jeong, Jae-Hyun"
  11. AU="Patsch, Wolfgang"
  12. AU="Garwood, Sarah K"
  13. AU="Pilon, Dominic"
  14. AU="Ignacio Cerro, C"
  15. AU=Jethani Bipin AU=Jethani Bipin

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Treffer 1 - 10 von insgesamt 241

Suchoptionen

  1. Buch: Endocrine immunology

    Savino, Wilson / Guaraldi, Federica

    (Frontiers of hormone research ; 48)

    2017  

    Verfasserangabe volume editors Wilson Savino, Federica Guaraldi
    Serientitel Frontiers of hormone research ; 48
    Überordnung
    Schlagwörter Endocrine System / immunology ; Endocrine System / physiology ; Immunomodulation / immunology ; Hormones / immunology ; Autoimmunity / immunology
    Sprache Englisch
    Umfang VII, 180 Seiten, Illustrationen, Diagramme
    Verlag Karger
    Erscheinungsort Basel
    Erscheinungsland Schweiz
    Dokumenttyp Buch
    HBZ-ID HT019282787
    ISBN 978-3-31806013-3 ; 9783318060140 ; 3-31806013-5 ; 3318060143
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Buch ; Konferenzbeitrag: Neuroimmunomodulation

    Savino, Wilson

    from fundamental biology to therapy ; [result of a conference entitled the VII congress of the International Society for Neuroimmunomodulation (ISNIM), held April 14 - 27, 2008 in Rio de Janeiro, Brazil

    (Annals of the New York Academy of Sciences ; 1153)

    2009  

    Körperschaft International Society for Neuroimmunomodulation
    Verfasserangabe ed. by Wilson Savino
    Serientitel Annals of the New York Academy of Sciences ; 1153
    Überordnung
    Sprache Englisch
    Umfang XI, 274 S. : Ill., graph. Darst.
    Verlag Blackwell
    Erscheinungsort Boston, Mass
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch ; Konferenzbeitrag
    HBZ-ID HT015862128
    ISBN 978-1-57331-746-7 ; 1-57331-746-2
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  3. Buch: Neuroendocrine immunology of the thymus

    Savino, Wilson / Dardenne, Mireille

    5 tables

    (Neuroimmunomodulation ; 18,5)

    2011  

    Verfasserangabe ed. Wilson Savino ; Mireille Dardenne
    Serientitel Neuroimmunomodulation ; 18,5
    Überordnung
    Sprache Englisch
    Umfang S. 263 - 357 : Ill., graph. Darst.
    Verlag Karger
    Erscheinungsort Basel u.a.
    Erscheinungsland Schweiz
    Dokumenttyp Buch
    HBZ-ID HT016982681
    ISBN 978-3-8055-9831-6 ; 3-8055-9831-9 ; 9783805598323 ; 3805598327
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  4. Buch ; Online: Hormones, Neurotransmitters, and T-Cell Development in Health and Disease

    Savino, Wilson / Areas Mendes-da-Cruz, Daniella / Rosa Pérez, Ana / Geenen, Vincent

    2019  

    Schlagwörter Medicine ; Endocrinology ; Glucocorticoids ; Growth hormone ; Sympathetic innervation ; Galectins ; Thymus ; Norepinephrine ; Ephrins ; Diabetes ; Infectious diseases ; Cytokines
    Umfang 1 electronic resource (110 pages)
    Verlag Frontiers Media SA
    Dokumenttyp Buch ; Online
    Anmerkung English ; Open Access
    HBZ-ID HT021231169
    ISBN 9782889630264 ; 2889630269
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  5. Buch: Neuroendocrine control of the thymus

    Savino, Wilson

    18 tables

    1999  

    Verfasserangabe ed. W. Savino
    Sprache Englisch
    Umfang 143 S. : Ill., graph. Darst.
    Ausgabenhinweis Reprint.
    Verlag Karger
    Erscheinungsort Basel u.a.
    Erscheinungsland Schweiz
    Dokumenttyp Buch
    Anmerkung Aus: Neuroimmunomodulation ; 6.1999,1-2
    HBZ-ID HT010079055
    ISBN 3-8055-6769-3 ; 978-3-8055-6769-5
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  6. Artikel: Thymus-derived hormonal and cellular control of cancer.

    Savino, Wilson / Lepletier, Ailin

    Frontiers in endocrinology

    2023  Band 14, Seite(n) 1168186

    Abstract: The thymus gland is a central lymphoid organ in which developing T cell precursors, known as thymocytes, undergo differentiation into distinct type of mature T cells, ultimately migrating to the periphery where they exert specialized effector functions ... ...

    Abstract The thymus gland is a central lymphoid organ in which developing T cell precursors, known as thymocytes, undergo differentiation into distinct type of mature T cells, ultimately migrating to the periphery where they exert specialized effector functions and orchestrate the immune responses against tumor cells, pathogens and self-antigens. The mechanisms supporting intrathymic T cell differentiation are pleiotropically regulated by thymic peptide hormones and cytokines produced by stromal cells in the thymic microenvironment and developing thymocytes. Interestingly, in the same way as T cells, thymic hormones (herein exemplified by thymosin, thymulin and thymopoietin), can circulate to impact immune cells and other cellular components in the periphery. Evidence on how thymic function influences tumor cell biology and response of patients with cancer to therapies remains unsatisfactory, although there has been some improvement in the knowledge provided by recent studies. Herein, we summarize research progression in the field of thymus-mediated immunoendocrine control of cancer, providing insights into how manipulation of the thymic microenvironment can influence treatment outcomes, including clinical responses and adverse effects of therapies. We review data obtained from clinical and preclinical cancer research to evidence the complexity of immunoendocrine interactions underpinning anti-tumor immunity.
    Mesh-Begriff(e) Humans ; Thymus Gland ; T-Lymphocytes ; Cytokines/metabolism ; Neoplasms/metabolism ; Peptides/metabolism ; Tumor Microenvironment
    Chemische Substanzen Cytokines ; Peptides
    Sprache Englisch
    Erscheinungsdatum 2023-07-17
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1168186
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Brain-Thymus Connections in Chagas Disease.

    González, Florencia Belén / Savino, Wilson / Pérez, Ana Rosa

    Neuroimmunomodulation

    2024  Band 31, Heft 1, Seite(n) 78–88

    Abstract: Background: The brain and the immune systems represent the two primary adaptive systems within the body. Both are involved in a dynamic process of communication, vital for the preservation of mammalian homeostasis. This interplay involves two major ... ...

    Abstract Background: The brain and the immune systems represent the two primary adaptive systems within the body. Both are involved in a dynamic process of communication, vital for the preservation of mammalian homeostasis. This interplay involves two major pathways: the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system.
    Summary: The establishment of infection can affect immunoneuroendocrine interactions, with functional consequences for immune organs, particularly the thymus. Interestingly, the physiology of this primary organ is not only under the control of the central nervous system (CNS) but also exhibits autocrine/paracrine regulatory circuitries mediated by hormones and neuropeptides that can be altered in situations of infectious stress or chronic inflammation. In particular, Chagas disease, caused by the protozoan parasite Trypanosoma cruzi (T. cruzi), impacts upon immunoneuroendocrine circuits disrupting thymus physiology. Here, we discuss the most relevant findings reported in relation to brain-thymic connections during T. cruzi infection, as well as their possible implications for the immunopathology of human Chagas disease.
    Key messages: During T. cruzi infection, the CNS influences thymus physiology through an intricate network involving hormones, neuropeptides, and pro-inflammatory cytokines. Despite some uncertainties in the mechanisms and the fact that the link between these abnormalities and chronic Chagasic cardiomyopathy is still unknown, it is evident that the precise control exerted by the brain over the thymus is markedly disrupted throughout the course of T. cruzi infection.
    Mesh-Begriff(e) Humans ; Chagas Disease/immunology ; Chagas Disease/physiopathology ; Animals ; Brain/immunology ; Thymus Gland/immunology ; Thymus Gland/physiology ; Trypanosoma cruzi/physiology ; Trypanosoma cruzi/immunology ; Hypothalamo-Hypophyseal System/immunology ; Hypothalamo-Hypophyseal System/metabolism ; Hypothalamo-Hypophyseal System/physiopathology ; Neuroimmunomodulation/physiology ; Neuroimmunomodulation/immunology ; Pituitary-Adrenal System/immunology ; Pituitary-Adrenal System/physiopathology ; Pituitary-Adrenal System/metabolism
    Sprache Englisch
    Erscheinungsdatum 2024-04-09
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1184368-8
    ISSN 1423-0216 ; 1021-7401
    ISSN (online) 1423-0216
    ISSN 1021-7401
    DOI 10.1159/000538220
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Buch ; Konferenzbeitrag: Proceedings of the 1st CEC FIOCRUZ Joint Meeting on Molecular and Cellular Basis of Virulence and Pathogenesis in Infectious and Parasitic Diseases

    Savino, Wilson

    Angra dos Reis, RJ, Brazil, 25 to 29 November, 1991

    (Memórias do Instituto Oswaldo Cruz ; 87, Suppl. 5)

    1992  

    Titelvarianten CEC-FIOCRUZ
    Körperschaft Europäische Kommission
    Veranstaltung/Kongress Joint Meeting Molecular and Cellular Basis of Virulence and Pathogenesis in Infectious and Parasitic Diseases (1, 1991, AngradosReis)
    Verfasserangabe guest ed. for this special issue: Wilson Savino
    Serientitel Memórias do Instituto Oswaldo Cruz ; 87, Suppl. 5
    Memorias do Instituto Oswaldo Cruz
    Überordnung Memorias do Instituto Oswaldo Cruz
    Schlagwörter Virulence / congresses ; Bacterial Infections / etiology / congresses ; Parasitic Diseases / etiology / congresses
    Sprache Englisch
    Umfang 149 S. : Ill., graph. Darst.
    Erscheinungsort Rio de Janeiro
    Erscheinungsland Brasilien
    Dokumenttyp Buch ; Konferenzbeitrag
    HBZ-ID HT006251368
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  9. Artikel: Developing anti-helminth vaccines for people and cattle: (For)seeing the

    Tendler, Miriam / Savino, Wilson / Almeida, Marilia Sirianni Dos Santos

    One health (Amsterdam, Netherlands)

    2023  Band 17, Seite(n) 100616

    Sprache Englisch
    Erscheinungsdatum 2023-08-18
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2834831-X
    ISSN 2352-7714
    ISSN 2352-7714
    DOI 10.1016/j.onehlt.2023.100616
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Prolactin: An Immunomodulator in Health and Disease.

    Savino, Wilson

    Frontiers of hormone research

    2017  Band 48, Seite(n) 69–75

    Abstract: Various lines of evidence show that prolactin (PRL) is an immunomodulator in health and disease. Cells of the immune system express PRL receptors and respond to the cognate ligand. Also, PRL itself is produced by several immune cells, indicating that in ... ...

    Abstract Various lines of evidence show that prolactin (PRL) is an immunomodulator in health and disease. Cells of the immune system express PRL receptors and respond to the cognate ligand. Also, PRL itself is produced by several immune cells, indicating that in addition to its classic endocrine effects, it may also act via paracrine/autocrine pathways. PRL stimulates B and T lymphocyte proliferation, and its excess is associated with the appearance or recrudescence of various systemic and organ-specific autoimmune diseases, as demonstrated by experimental studies performed in mice, and by human case reports and case control studies. Very recently, dopamine agonists have been demonstrated to be efficacious in the treatment of some autoimmune disorders, placing PRL-mediated interactions as potential therapeutic targets for treating autoimmunity.
    Mesh-Begriff(e) Animals ; Autoimmune Diseases/metabolism ; Autoimmune Diseases/therapy ; Humans ; Immunomodulation/physiology ; Prolactin/metabolism
    Chemische Substanzen Prolactin (9002-62-4)
    Sprache Englisch
    Erscheinungsdatum 2017
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ISSN 1662-3762 ; 0301-3073
    ISSN (online) 1662-3762
    ISSN 0301-3073
    DOI 10.1159/000452906
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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