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  1. AU="Wu, J" AU="Wu, J"
  2. AU="Kotsubo, Vincent Y"
  3. AU="Sladek, Frances M"
  4. AU="Sevillya, Gur"
  5. AU="Jia, Jinhui"
  6. AU="Valero, Sergi"
  7. AU="Lu, Chia-Jung"
  8. AU="Patel, Nakul"
  9. AU=Cerdena Jessica P
  10. AU="Cano, Suzana Faria"
  11. AU="Richardson, Kathryn"
  12. AU="Tsourouflis, Gerassimos"
  13. AU="Srai, S K"
  14. AU="Or, Charles C-F"
  15. AU="Rohin, Francis"
  16. AU="Natália Pinto de Almeida"
  17. AU="Spagnolo-Allende, Antonio J"
  18. AU="Jenninger, B"
  19. AU="Kerenza Hood"
  20. AU="Khan Chachar, Aijaz Zeeshan"
  21. AU="Yuan, Weiming"

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  1. Buch ; Online ; E-Book: Biomanufacture of Functional Carbohydrates

    Wu, Jing / Su, Lingqia

    2024  

    Abstract: Biomanufacture of Functional Carbohydrates provides the systemic introduction of biomanufacture of 10 functional carbohydrates. Each chapter introduces the function and application of a functional carbohydrate, then focuses on the recent advancements of ... ...

    Verfasserangabe Jing Wu and Lingqia Su
    Abstract Biomanufacture of Functional Carbohydrates provides the systemic introduction of biomanufacture of 10 functional carbohydrates. Each chapter introduces the function and application of a functional carbohydrate, then focuses on the recent advancements of the enzymes and catalytic pathways associated with its biosynthesis.
    Schlagwörter Functional foods ; Carbohydrates in human nutrition
    Thema/Rubrik (Code) 664/.15
    Sprache Englisch
    Umfang 1 online resource (376 pages)
    Ausgabenhinweis First edition.
    Verlag CRC Press
    Erscheinungsort Boca Raton, FL
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-04-000811-9 ; 1-003-37264-3 ; 1-03-243815-0 ; 978-1-04-000811-9 ; 978-1-003-37264-6 ; 978-1-03-243815-3
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Buch ; Online ; E-Book: Single-Arm phase II survival trial design

    Wu, Jianrong

    (Chapman and Hall/CRC biostatistics series)

    2022  

    Titelvarianten Single arm phase II survival trial design
    Verfasserangabe Jianrong Wu
    Serientitel Chapman and Hall/CRC biostatistics series
    Sprache Englisch
    Umfang 1 Online-Ressource (x, 263 Seiten), Illustrationen, Diagramme
    Ausgabenhinweis First edition
    Verlag CRC Press LLC
    Erscheinungsort Milton
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021344293
    ISBN 9781000421736 ; 9781003129059 ; 9780367653491 ; 9780367653453 ; 1000421732 ; 1003129056 ; 0367653494 ; 0367653451
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  3. Buch ; Online ; E-Book: Quantitative analysis and modeling of earth and environmental data

    Wu, Jiaping / He, Junyu / Christakos, George

    space-time and spacetime data considerations

    2022  

    Verfasserangabe Jiaping Wu, Junyu He, George Christakos
    Schlagwörter Environmental monitoring ; Environmental sciences/Data processing ; Spatial analysis (Statistics)
    Sprache Englisch
    Umfang 1 online resource (504 pages)
    Verlag Elsevier
    Erscheinungsort Amsterdam
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-12-816342-9 ; 9780128163412 ; 978-0-12-816342-9 ; 0128163410
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  4. Buch ; Online ; E-Book: Transmission dynamics of tick-borne diseases with co-feeding, developmental and behavioural diapause

    Wu, Jianhong / Zhang, Xue

    (Lecture notes on mathematical modelling in the life sciences)

    2020  

    Abstract: This monograph introduces some current developments in the modelling of the spread of tick-borne diseases. Effective modelling requires the integration of multiple frameworks. Here, particular attention is given to the previously neglected issues of tick ...

    Verfasserangabe Jianhong Wu, Xue Zhang
    Serientitel Lecture notes on mathematical modelling in the life sciences
    Abstract This monograph introduces some current developments in the modelling of the spread of tick-borne diseases. Effective modelling requires the integration of multiple frameworks. Here, particular attention is given to the previously neglected issues of tick developmental and behavioral diapause, tick-borne pathogen co-feeding transmission, and their interactions. An introduction to the required basics of structured population formulations and delay differential equations is given, and topics for future study are suggested. The described techniques will also be useful in the study of other vector-borne diseases. The ultimate aim of this project is to develop a general qualitative framework leading to tick-borne disease risk predictive tools and a decision support system. The target audience is mathematical biologists interested in modelling tick population dynamics and tick-borne disease transmission, and developing computational tools for disease prevention and control.
    Schlagwörter Tick-borne diseases
    Thema/Rubrik (Code) 616.968
    Sprache Englisch
    Umfang 1 online resource (XIII, 160 p. 24 illus., 21 illus. in color.)
    Ausgabenhinweis 1st ed. 2020.
    Verlag Springer
    Erscheinungsort Cham, Switzerland
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-54024-3 ; 3-030-54023-5 ; 978-3-030-54024-1 ; 978-3-030-54023-4
    DOI 10.1007/978-3-030-54024-1
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  5. Buch ; Online ; E-Book: Environmental Management in China

    Wu, Jing / Chang, I-Shin

    Policies and Institutions

    2020  

    Abstract: This book details various stages in the introduction, establishment and evolution of China’s environmental management system. By combining a literature review, comparative analysis, and case study, it investigates the environmental management system in ... ...

    Verfasserangabe by Jing Wu, I-Shin Chang
    Abstract This book details various stages in the introduction, establishment and evolution of China’s environmental management system. By combining a literature review, comparative analysis, and case study, it investigates the environmental management system in several key periods in order to systematically assess the necessary measures and appropriate adjustments the Chinese Government implemented to reconcile the growing conflicts between economic development and resources conservation, in the context of rapid economic growth and economic transformation. Given its scope, the book offers a valuable resource for experts, scholars, and government officials in related fields. .
    Schlagwörter Environmental management ; Environmental law. ; Environmental policy ; Sustainable development ; Environmental Management ; Environmental Law/Policy/Ecojustice ; Sustainable Development
    Thema/Rubrik (Code) 333.70951
    Sprache Englisch
    Umfang 1 online resource (278 pages)
    Ausgabenhinweis 1st ed. 2020.
    Verlag Springer Singapore ; Imprint: Springer
    Erscheinungsort Singapore
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-15-4894-3 ; 981-15-4893-5 ; 978-981-15-4894-9 ; 978-981-15-4893-2
    DOI 10.1007/978-981-15-4894-9
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  6. Artikel: Lychee Seed Saponins Improve Cognitive Function and Prevent Neuronal Injury via Inhibiting Neuronal Apoptosis in a Rat Model of Alzheimer’s Disease

    Wu, Jianming

    Nutrients, 9(2):105

    2017  

    Abstract: Lychee seed is a traditional Chinese medicine and possesses many activities, including hypoglycemia, liver protection, antioxidation, antivirus, and antitumor. However, its effect on neuroprotection is still unclear. The present study investigated the ... ...

    Abstract Lychee seed is a traditional Chinese medicine and possesses many activities, including hypoglycemia, liver protection, antioxidation, antivirus, and antitumor. However, its effect on neuroprotection is still unclear. The present study investigated the effects of lychee seed saponins (LSS) on neuroprotection and associated mechanisms. We established a rat model of Alzheimer’s disease (AD) by injecting Aβ25–35 into the lateral ventricle of rats and evaluated the effect of LSS on spatial learning and memory ability via the Morris water maze. Neuronal apoptosis was analyzed by hematoxylin and eosin stain and terminal deoxynucleotidyl transferase (Tdt)-mediated dUTP nick-end labeling analysis, and mRNA expression of caspase-3 and protein expressions of Bax and Bcl-2 by reverse transcription-polymerase chain reaction (RT-PCR) and Western blotting, respectively. The results showed that LSS remarkably improved cognitive function and alleviated neuronal injury by inhibiting apoptosis in the hippocampus of AD rats. Furthermore, the mRNA expression of caspase-3 and the protein expression of Bax were downregulated, while the protein expression of Bcl-2 and the ratio of Bcl-2/Bax were increased by LSS. We demonstrate that LSS significantly improves cognitive function and prevent neuronal injury in the AD rats via regulation of the apoptosis pathway. Therefore, LSS may be developed as a nutritional supplement and sold as a drug for AD prevention and/or treatment.
    Schlagwörter Alzheimer’s disease ; cognitive function ; apoptosis ; lychee seed saponins ; neuronal injury ; rat model of Alzheimer’s disease
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle Fachrepositorium Lebenswissenschaften

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  7. Buch ; Online: Molecular Regulation and Therapeutic Potential of Thermogenic Fat Cells

    Wu, Jun

    2016  

    Abstract: Obesity has emerged as a major threat to public health in both the western and developing world. Essentially a disorder of energy balance, obesity occurs when energy intake and storage exceeds expenditure. Much of energy homeostasis depends on the ... ...

    Abstract Obesity has emerged as a major threat to public health in both the western and developing world. Essentially a disorder of energy balance, obesity occurs when energy intake and storage exceeds expenditure. Much of energy homeostasis depends on the activity and function of adipose tissue. Adipocytes in mammals fall into two categories classified by their primary functions: white fat cells that mediate energy storage and thermogenic fat cells that counteract hypothermia and obesity through adaptive thermogenesis. Whereas white fat and its function as an energy reservoir and endocrine organ have been studied for decades and are relatively well understood, until recently many aspects of the thermogenic fat biology have remained elusive. Accumulating evidence supports the hypothesis that thermogenic fat cells arise from at least two different developmental origins: the ones of a skeletal muscle-like lineage are now called "classical" brown fat cells, and the rest of the thermogenic fat cells are normally referred to as the beige fat cells. The last decade has witnessed an explosion of interest and studies focusing on the regulation of thermogenic fat cells and potential therapeutics targeting these adipocytes. Here we summarize the recent advancements in our understanding of these metabolically active fat cells
    Schlagwörter Diseases of the endocrine glands. Clinical endocrinology ; Medicine (General)
    Umfang 1 electronic resource (127 p.)
    Verlag Frontiers Media SA
    Dokumenttyp Buch ; Online
    Anmerkung English ; Open Access
    HBZ-ID HT020090590
    ISBN 9782889198696 ; 2889198693
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  8. Buch ; Online: Fatty Acids and Cardiometabolic Health

    Wu, Jason / Marklund, Matti

    2019  

    Abstract: The impact of fat intake on hypercholesterolemia and related atherosclerotic cardiovascular diseases has been studied for decades. However, the current evidence base suggests that fatty acids also influences cardiometabolic diseases through other ... ...

    Abstract The impact of fat intake on hypercholesterolemia and related atherosclerotic cardiovascular diseases has been studied for decades. However, the current evidence base suggests that fatty acids also influences cardiometabolic diseases through other mechanisms including effects on glucose metabolism, body fat distribution, blood pressure, inflammation, and heart rate. Furthermore, studies evaluating single fatty acids have challenged the simplistic view of shared health effects within fatty acid groups categorized by degree of saturation. In addition, investigations of endogenous fatty acid metabolism, including genetic studies of fatty acid metabolizing enzymes, and the identification of novel metabolically derived fatty acids have further increased the complexity of fatty acids' health impacts. This Special Issue aims to include original research and up-to-date reviews on genetic and dietary modulation of fatty acids, and the role and function of dietary and metabolically derived fatty acids in cardiometabolic health
    Schlagwörter Science (General) ; Biology (General) ; Nutrition. Foods and food supply
    Umfang 1 electronic resource (202 p.)
    Verlag MDPI - Multidisciplinary Digital Publishing Institute
    Erscheinungsort Verlagsort nicht ermittelbar
    Dokumenttyp Buch ; Online
    Anmerkung eng ; Open Access
    HBZ-ID HT020195708
    ISBN 9783038978909 ; 9783038978916 ; 3038978906 ; 3038978914
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  9. Artikel ; Online: Hyperspectral imaging for non-invasive blood oxygen saturation assessment.

    Wu, Jiangbo

    Photodiagnosis and photodynamic therapy

    2024  Band 45, Seite(n) 104003

    Abstract: Hyperspectral Imaging (HSI) seamlessly integrates imaging and spectroscopy, capturing both spatial and spectral data concurrently. With widespread applications in medical diagnostics, HSI serves as a noninvasive tool for gaining insights into tissue ... ...

    Abstract Hyperspectral Imaging (HSI) seamlessly integrates imaging and spectroscopy, capturing both spatial and spectral data concurrently. With widespread applications in medical diagnostics, HSI serves as a noninvasive tool for gaining insights into tissue characteristics. The distinctive spectral profiles of biological tissues set HSI apart from traditional microscopy in enabling in vivo tissue analysis. Despite its potential, existing HSI techniques face challenges such as alignment issues, low light throughput, and tissue heating due to intense illumination. This study introduces an innovative HSI system featuring active sequential bandpass illumination seamlessly integrated into conventional optical instruments. The primary focus is on analyzing oxyhemoglobin and deoxyhemoglobin saturation in animal tissue samples using multivariate linear regression. This approach holds promise for enhancing noninvasive medical diagnostics. A key feature of the system, active bandpass illumination, effectively prevents tissue overheating, thereby bolstering its suitability for medical applications.
    Mesh-Begriff(e) Animals ; Hyperspectral Imaging ; Oxygen Saturation ; Photochemotherapy/methods ; Photosensitizing Agents ; Lighting
    Chemische Substanzen Photosensitizing Agents
    Sprache Englisch
    Erscheinungsdatum 2024-02-08
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2149918-4
    ISSN 1873-1597 ; 1572-1000
    ISSN (online) 1873-1597
    ISSN 1572-1000
    DOI 10.1016/j.pdpdt.2024.104003
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Emerging Innate Immune Cells in Cancer Immunotherapy: Promises and Challenges.

    Wu, Jennifer

    BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

    2024  

    Abstract: Immune checkpoint inhibitor (ICI)-based therapy has made an unprecedented impact on survival benefit for a subset of cancer patients; however, only a subset of cancer patients is benefiting from ICI therapy if all cancer types are considered. With the ... ...

    Abstract Immune checkpoint inhibitor (ICI)-based therapy has made an unprecedented impact on survival benefit for a subset of cancer patients; however, only a subset of cancer patients is benefiting from ICI therapy if all cancer types are considered. With the advanced understanding of interactions of immune effector cell types and tumors, cell-based therapies are emerging as alternatives to patients who could not benefit from ICI therapy. Pioneering work of chimeric antigen receptor T (CAR-T) therapy for hematological malignancies has brought encouragement to a broad range of development for cellular-based cancer immunotherapy, both innate immune cell-based therapies and T-cell-based therapies. Innate immune cells are important cell types due to their rapid response, versatile function, superior safety profiles being demonstrated in early clinical development, and being able to utilize multiple allogeneic cell sources. Efforts on engineering innate immune cells and exploring their therapeutic potential are rapidly emerging. Some of the therapies, such as CD19 CAR natural killer (CAR-NK) cell-based therapy, have demonstrated comparable early efficacy with CD19 CAR-T cells. These studies underscore the significance of developing innate immune cells for cancer therapy. In this review, we focus on the current development of emerging NK cells, γδ T cells, and macrophages. We also present our views on potential challenges and perspectives to overcome these challenges.
    Sprache Englisch
    Erscheinungsdatum 2024-05-03
    Erscheinungsland New Zealand
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1364202-9
    ISSN 1179-190X ; 1173-8804
    ISSN (online) 1179-190X
    ISSN 1173-8804
    DOI 10.1007/s40259-024-00657-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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