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  1. Article ; Online: Corrigendum to "How do biases in sex ratio and disease characteristics affect the spread of sexually transmitted infections?" [J. Theor. Biol. 527 (2021) 110832].

    Halimubieke, Naerhulan / Pirrie, Alistair / Székely, Tamás / Ashby, Ben

    Journal of theoretical biology

    2023  Volume 571, Page(s) 111545

    Language English
    Publishing date 2023-06-16
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2972-5
    ISSN 1095-8541 ; 0022-5193
    ISSN (online) 1095-8541
    ISSN 0022-5193
    DOI 10.1016/j.jtbi.2023.111545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comments to: "Risk factors for a false negative Ortolani and Barlow examination in developmental dysplasia of the hip" by SHS Tan, JXY Lim, AKS Lim, JHP Hui published in Orthop Traumatol Surg Res 2023:103796. doi: 10.1016/j.otsr.2023.103796.

    Rehm, Andreas / Thahir, Azeem / Judkins, Nicholas / Hatzantoni, Katerina / Newton, Ayla C / Ashby, Elizabeth

    Orthopaedics & traumatology, surgery & research : OTSR

    2024  , Page(s) 103893

    Language English
    Publishing date 2024-04-22
    Publishing country France
    Document type Letter
    ISSN 1877-0568
    ISSN (online) 1877-0568
    DOI 10.1016/j.otsr.2024.103893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comments on: "Surgical treatment of congenital pseudarthrosis of the clavicle: a series of 10 cases" by M. Payen, N. Mainard, F. Accadbled, J. Sales de Gauzy, A. Abid published in Orthop Traumatol Surg Res 2022:103518.

    Rehm, Andreas / Hatzantoni, Katerina / Linardatou Novak, Pinelopi / Clegg, Rachael / Ashby, Elizabeth

    Orthopaedics & traumatology, surgery & research : OTSR

    2023  Volume 110, Issue 1, Page(s) 103752

    MeSH term(s) Humans ; Pseudarthrosis/surgery ; Clavicle
    Language English
    Publishing date 2023-11-14
    Publishing country France
    Document type Letter
    ISSN 1877-0568
    ISSN (online) 1877-0568
    DOI 10.1016/j.otsr.2023.103752
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: "Changes in the management of pediatric medial humeral epicondyle fractures with and without associated elbow dislocation." Scherer S, Dietzel M, Jordan N, Tsiflikas I, Kirschner HJ, Fuchs J, Lieber J. Injury 2021;52:2257-2264.

    Rehm, Andreas / Kobezda, Tamás / Ong, Joshua C Y / Ashby, Elizabeth

    Injury

    2021  Volume 53, Issue 3, Page(s) 1297–1298

    MeSH term(s) Child ; Elbow/injuries ; Humans ; Humeral Fractures/complications ; Humeral Fractures/surgery ; Humerus ; Joint Dislocations/complications
    Language English
    Publishing date 2021-11-29
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 218778-4
    ISSN 1879-0267 ; 0020-1383
    ISSN (online) 1879-0267
    ISSN 0020-1383
    DOI 10.1016/j.injury.2021.11.059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Coevolution of Age-Structured Tolerance and Virulence.

    Buckingham, Lydia J / Ashby, Ben

    Bulletin of mathematical biology

    2024  Volume 86, Issue 6, Page(s) 62

    Abstract: Hosts can evolve a variety of defences against parasitism, including resistance (which prevents or reduces the spread of infection) and tolerance (which protects against virulence). Some organisms have evolved different levels of tolerance at different ... ...

    Abstract Hosts can evolve a variety of defences against parasitism, including resistance (which prevents or reduces the spread of infection) and tolerance (which protects against virulence). Some organisms have evolved different levels of tolerance at different life-stages, which is likely to be the result of coevolution with pathogens, and yet it is currently unclear how coevolution drives patterns of age-specific tolerance. Here, we use a model of tolerance-virulence coevolution to investigate how age structure influences coevolutionary dynamics. Specifically, we explore how coevolution unfolds when tolerance and virulence (disease-induced mortality) are age-specific compared to when these traits are uniform across the host lifespan. We find that coevolutionary cycling is relatively common when host tolerance is age-specific, but cycling does not occur when tolerance is the same across all ages. We also find that age-structured tolerance can lead to selection for higher virulence in shorter-lived than in longer-lived hosts, whereas non-age-structured tolerance always leads virulence to increase with host lifespan. Our findings therefore suggest that age structure can have substantial qualitative impacts on host-pathogen coevolution.
    MeSH term(s) Virulence ; Animals ; Host-Pathogen Interactions ; Mathematical Concepts ; Age Factors ; Biological Evolution ; Models, Biological ; Host-Parasite Interactions/immunology ; Biological Coevolution ; Humans ; Longevity
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 184905-0
    ISSN 1522-9602 ; 0007-4985 ; 0092-8240
    ISSN (online) 1522-9602
    ISSN 0007-4985 ; 0092-8240
    DOI 10.1007/s11538-024-01292-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Managing patients with eating disorders: a qualitative study in primary care.

    Ashby, Carrie / Ogden, Jane

    BJGP open

    2024  

    Abstract: Background: General Practitioners (GPs) play a key role in the diagnosis and management of eating disorders (EDs).: Aim: To explore GPs' experiences of managing patients with eating disorders (EDs).: Design & setting: A qualitative study utilising ...

    Abstract Background: General Practitioners (GPs) play a key role in the diagnosis and management of eating disorders (EDs).
    Aim: To explore GPs' experiences of managing patients with eating disorders (EDs).
    Design & setting: A qualitative study utilising remote semi-structured interviews.
    Method: Fourteen GPs were interviewed about their experiences of supporting patients with EDs. The interviews were recorded, transcribed and analysed using thematic analysis.
    Results: The analysis described four themes: i) 'Continuity of care' addressing the GPs relationship with patients and family, patients transitions across life stages and geographical areas and patient non-attendance; ii) 'The role of guidance' focusing on guidelines and protocols, referrals and specialist professionals as points of contact; iii) 'Structural barriers' including waiting times, lack of resources, referral criteria and relationships between services; iv) 'Confidence and skills' reflecting professional and personal experience in EDs, previous training and training needs. Transcending these themes was the notion of the 'Limits to the care' GPs can provide due to professional boundaries and the emotional impact of managing patients with EDs.
    Conclusion: This study found that whilst GPs want to help patients with EDs many limits remain to the care they can provide due to both internal and external factors. Funding is required for training and accessible specialist ED support and greater clarity is needed regarding referral processes if ED management in Primary Care is to be optimised.
    Language English
    Publishing date 2024-04-30
    Publishing country England
    Document type Journal Article
    ISSN 2398-3795
    ISSN (online) 2398-3795
    DOI 10.3399/BJGPO.2024.0014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Conference proceedings ; Online: Design elements for gender-responsive breeding

    Ashby, Jacqueline

    Starting points and unresolved issues

    2022  

    Abstract: Presented by Jacqueline Ashby on 21 September 2017, as part of the webinar 'Design elements ...

    Abstract Presented by Jacqueline Ashby on 21 September 2017, as part of the webinar 'Design elements for gender-responsive breeding'. The webinar was co-organized by the CGIAR Collaborative Platform for Gender Research and the CGIAR Research Program on Roots, Tubers and Bananas.
    Keywords research ; gender ; bananas ; breeding ; roots ; tubers ; elements ; program
    Language English
    Publishing date 2022-08-23T17:35:39Z
    Publisher CGIAR Consortium
    Publishing country fr
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Conference proceedings ; Online: A practical decision checklist for gender-responsive plant and animal breeding

    Ashby, Jacqueline

    2022  

    Abstract: ... of these presentations, given by Jacqueline Ashby. ...

    Abstract This presentation was given during a webinar on May 17, 2018. This is the first of these presentations, given by Jacqueline Ashby.
    Keywords gender ; animal breeding ; breeding ; plant ; animal
    Language English
    Publishing date 2022-08-23T17:35:32Z
    Publisher CGIAR Consortium
    Publishing country fr
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Conference proceedings ; Online: Why isn't gender just about impact?

    Ashby, Jacqueline

    2022  

    Abstract: Presented by Jacqui Ashby, CGIAR Consortium Office at the Joint Pan African Grain Legumes and World ...

    Abstract Presented by Jacqui Ashby, CGIAR Consortium Office at the Joint Pan African Grain Legumes and World Cowpea Conference
    Keywords gender ; legumes ; grain legumes ; grain ; office
    Language English
    Publishing date 2022-08-23T17:35:51Z
    Publisher CGIAR Consortium
    Publishing country fr
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: The Evolution of the Age of Onset of Resistance to Infectious Disease.

    Buckingham, Lydia J / Ashby, Ben

    Bulletin of mathematical biology

    2023  Volume 85, Issue 5, Page(s) 42

    Abstract: Many organisms experience an increase in disease resistance as they age, but the time of life at which this change occurs varies. Increases in resistance are partially due to prior exposure and physiological constraints, but these cannot fully explain ... ...

    Abstract Many organisms experience an increase in disease resistance as they age, but the time of life at which this change occurs varies. Increases in resistance are partially due to prior exposure and physiological constraints, but these cannot fully explain the observed patterns of age-related resistance. An alternative explanation is that developing resistance at an earlier age incurs costs to other life-history traits. Here, we explore how trade-offs with host reproduction or mortality affect the evolution of the onset of resistance, depending on when during the host's life cycle the costs are paid (only when resistance is developing, only when resistant or throughout the lifetime). We find that the timing of the costs is crucial to determining evolutionary outcomes, often making the difference between resistance developing at an early or late age. Accurate modelling of biological systems therefore relies on knowing not only the shape of trade-offs but also when they take effect. We also find that the evolution of the rate of onset of resistance can result in evolutionary branching. This provides an alternative, possible evolutionary history of populations which are dimorphic in disease resistance, where the rate of onset of resistance has diversified rather than the level of resistance.
    MeSH term(s) Humans ; Disease Resistance/genetics ; Age of Onset ; Biological Evolution ; Models, Biological ; Mathematical Concepts ; Communicable Diseases/epidemiology
    Language English
    Publishing date 2023-04-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 184905-0
    ISSN 1522-9602 ; 0007-4985 ; 0092-8240
    ISSN (online) 1522-9602
    ISSN 0007-4985 ; 0092-8240
    DOI 10.1007/s11538-023-01144-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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