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  1. AU="Li, Yunfeng" AU="Li, Yunfeng"
  2. AU="Shankar, Ganesh"
  3. AU="Ruginsk, Silvia G"
  4. AU="Aquilante, Francesco"
  5. AU="Dillon, Robert C"
  6. AU="Yuan Qu"
  7. AU="Dufour, A"
  8. AU="Hannus, Jill"
  9. AU="Rieber, Julia"
  10. AU="Gulmuradov, Tashpulat"
  11. AU="Romeu Fontanillas, Teresa"
  12. AU="Fleming, Renée"
  13. AU="Cao, Fang"
  14. AU="Sally J L Moore"
  15. AU="Moreno, Yolanda"
  16. AU="Vasiliy Ya. Kolyuchkin"

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  1. Artikel ; Online: Letter on "Achalasia is Strongly Associated With Eosinophilic Esophagitis and Other Allergic Disorders".

    Li, Yun-Feng / Gau, Shuo-Yan

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2023  Band 22, Heft 5, Seite(n) 1144–1145

    Mesh-Begriff(e) Humans ; Esophageal Achalasia/complications ; Esophageal Achalasia/diagnosis ; Eosinophilic Esophagitis/complications ; Eosinophilic Esophagitis/diagnosis ; Hypersensitivity/complications
    Sprache Englisch
    Erscheinungsdatum 2023-09-13
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2023.08.030
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: A hypothesis of monoamine (5-HT) - Glutamate/GABA long neural circuit: Aiming for fast-onset antidepressant discovery.

    Li, Yun-Feng

    Pharmacology & therapeutics

    2020  Band 208, Seite(n) 107494

    Abstract: Major depressive disorder has become a global public health problem of serious concern. Most of the clinical antidepressants are developed under the classic "monoamine hypothesis (strategy)". These drugs generally have such deficiencies including slow ... ...

    Abstract Major depressive disorder has become a global public health problem of serious concern. Most of the clinical antidepressants are developed under the classic "monoamine hypothesis (strategy)". These drugs generally have such deficiencies including slow onset and limited efficiency, cognitive impairment and suicidal tendency. Therefore, it is the direction to break through the classic monoamine strategy framework for developing antidepressants that have fast-acting, lower side effects, and cognitive enhancement, to satisfy the major clinical needs. In 2019, the launch of fast-acting antidepressants such as S-ketamine(S-Ket) and brexanolone into market by FDA has opened up new prospects for non-monoamine strategy mainly based on the N-methyl-d-aspartate (NMDA) and γ-aminobutyric acid type A (GABA
    Mesh-Begriff(e) Animals ; Antidepressive Agents/therapeutic use ; Depressive Disorder, Major/drug therapy ; Depressive Disorder, Major/physiopathology ; Drug Discovery ; Glutamic Acid/physiology ; Humans ; Neurons/physiology ; Serotonin/physiology ; gamma-Aminobutyric Acid/physiology
    Chemische Substanzen Antidepressive Agents ; Serotonin (333DO1RDJY) ; Glutamic Acid (3KX376GY7L) ; gamma-Aminobutyric Acid (56-12-2)
    Sprache Englisch
    Erscheinungsdatum 2020-01-25
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 194735-7
    ISSN 1879-016X ; 0163-7258
    ISSN (online) 1879-016X
    ISSN 0163-7258
    DOI 10.1016/j.pharmthera.2020.107494
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: BSSRO Improves Mandibular Morphology Mainly through Correction of Body Length and Volume in Patients with Asymmetric Mandibular Prognathism.

    Liu, Yanfei / Li, Yunfeng

    Journal of clinical medicine

    2022  Band 11, Heft 23

    Abstract: Purpose: The purpose of this study is to analyze the change and stability of mandibular morphology in patients with asymmetric mandibular prognathism after bilateral sagittal split ramus osteotomy (BSSRO). Methods: We retrospectively analyzed fifty ... ...

    Abstract Purpose: The purpose of this study is to analyze the change and stability of mandibular morphology in patients with asymmetric mandibular prognathism after bilateral sagittal split ramus osteotomy (BSSRO). Methods: We retrospectively analyzed fifty patients with asymmetric mandibular prognathism from the West China Hospital of Stomatology, Sichuan University, between January 2018 to March 2021. The spiral CT data before surgery, within two weeks after surgery, and at more than six months after surgery of each patient were collected. According to the deflection direction of the chin, the bilateral mandibles were defined as the long side and the short side. The morphological data of the bilateral condyle, the mandibular ramus, and the mandibular body were analyzed to determine the effect and stability of BSSRO on asymmetric mandibular prognathism. Results: It was found that the long-side mandible had greater condylar volume and diameter, mandibular ramus height and volume, and mandibular body length and volume (p < 0.05) before surgery. After surgery, the volume of the mandibular ramus increased, while the length and volume of the mandibular body decreased (p < 0.05) at the long side of the mandible; the morphological changes of the mandibular ramus and body at the short side of the mandible were not statistically significant (p > 0.05). When comparing the long and short sides of the mandible, the long side still had greater height and volume of the mandibular ramus (p < 0.01). The volume difference of the mandibular body from the two sides was corrected (p > 0.05), and the length difference of the mandibular body from the two sides was overcorrected (p < 0.05). At more than six months after surgery, the volume of the mandibular ramus and body increased, while their height decreased at the long side of the mandible (p < 0.05). For the other side, or the short side, the volume of the ramus and body increased, too. However, their height decreased (p < 0.01). Conclusion: The results of this study suggested good effect and stability of BSSRO on asymmetric mandibular prognathism, except for the correction of ramus height and volume.
    Sprache Englisch
    Erscheinungsdatum 2022-11-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11237131
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Static hand gesture recognition based on hierarchical decision and classification of finger features.

    Li, Yunfeng / Zhang, Pengyue

    Science progress

    2022  Band 105, Heft 1, Seite(n) 368504221086362

    Abstract: ... ...

    Abstract Abstract
    Mesh-Begriff(e) Algorithms ; Fingers ; Gestures ; Pattern Recognition, Automated/methods ; Recognition, Psychology
    Sprache Englisch
    Erscheinungsdatum 2022-03-15
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 128412-5
    ISSN 2047-7163 ; 0036-8504 ; 0302-1785
    ISSN (online) 2047-7163
    ISSN 0036-8504 ; 0302-1785
    DOI 10.1177/00368504221086362
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  5. Artikel ; Online: Calculation method for the static carrying curve of double-row different-diameter ball slewing bearings.

    Li, Yunfeng / Wang, Rundong / Mao, Feiran

    Science progress

    2023  Band 106, Heft 2, Seite(n) 368504231180026

    Abstract: A method for calculating the static carrying curve of a double-row different-diameter ball slewing bearing was proposed. The relationship between the internal maximum rolling element load of each row and the combined external axial load and tilting ... ...

    Abstract A method for calculating the static carrying curve of a double-row different-diameter ball slewing bearing was proposed. The relationship between the internal maximum rolling element load of each row and the combined external axial load and tilting moment load of the slewing bearing was established using the deformation compatibility and force equilibrium conditions. The rolling element load distribution range parameters of the main and auxiliary raceways of the double-row different-diameter ball slewing bearing were used as input invariables, and the corresponding external load combinations of the axial and tilting moment loads of the slewing bearing were obtained. These external load combinations were plotted in the coordinate system to obtain the static carrying curve of the slewing bearing. The obtained static carrying curve was compared with that calculated using the finite element method for verification. Finally, the influences of detailed design parameters such as the raceway groove radius coefficient, raceway contact angle, and rolling element diameter on the carrying capacity of the double-row different-diameter ball slewing bearing were analyzed based on the carrying curves. As the groove radius coefficient increases from 0.515 to 0.530, or the contact angle increases from 50° to 65°, the carrying capacity of the slewing bearing decreases. As the rolling element diameter increases from 0.90 times the initial diameter to 1.05 times the initial diameter, the carrying capacity of the slewing bearing increases.
    Sprache Englisch
    Erscheinungsdatum 2023-06-20
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 128412-5
    ISSN 2047-7163 ; 0036-8504 ; 0302-1785
    ISSN (online) 2047-7163
    ISSN 0036-8504 ; 0302-1785
    DOI 10.1177/00368504231180026
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  6. Artikel ; Online: Comprehensive correction of maxillofacial bone deformity-consideration and combined application of orthognathic surgery and facial contouring surgery.

    Zhu, Song-Song / Li, Yun-Feng

    Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

    2021  Band 39, Heft 3, Seite(n) 255–259

    Abstract: The maxillofacial skeleton is the basis of the contour of the face. Orthognathic surgery and facial contouring surgery change jaw tissue and affect facial appearance in different manners. Orthognathic surgery is the main method to correct dental and ... ...

    Abstract The maxillofacial skeleton is the basis of the contour of the face. Orthognathic surgery and facial contouring surgery change jaw tissue and affect facial appearance in different manners. Orthognathic surgery is the main method to correct dental and maxillofacial deformities. It changes the shape of the jaw and improves the occlusal relationship by changing the three-dimensional position of the jaw. Facial contouring surgery mainly adopts the method of "bone reduction", which changes the "amount"of the jawbone by cutting a part of the bone tissue to improve the facial appearance, generally without changing oral function. The combined use of orthognathic surgery and facial contouring surgery is becoming increasingly common in clinical practice. This also requires oral and maxillofacial surgeons to have a holistic consideration of the comprehensive correction of maxillofacial bone deformity, and to perform comprehensive analysis of jaw deformities and jaw plastic surgery to achieve the most ideal results. The author's team has been engaged in the clinical work of orthognathic surgery and facial contouring surgery and accumulated rich clinical experience in the comprehensive correction of maxillofacial bone deformity. In this article, the indications, treatment goals, treatment modes, treatment methods, and key points in the surgical operations of comprehensive maxillofacial bone surgery were summarized.
    Mesh-Begriff(e) Face/surgery ; Facial Bones ; Humans ; Maxillofacial Abnormalities ; Orthognathic Surgery ; Orthognathic Surgical Procedures
    Sprache Chinesisch
    Erscheinungsdatum 2021-05-26
    Erscheinungsland China
    Dokumenttyp Journal Article
    ZDB-ID 1202342-5
    ISSN 2618-0456 ; 1000-1182
    ISSN (online) 2618-0456
    ISSN 1000-1182
    DOI 10.7518/hxkq.2021.03.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Simulation of Daily Transpiration of Tomatoes Grown in Venlo-Type Greenhouse Substrates.

    Yi, Ping / Qiang, Xiaoman / Liu, Shengxing / Han, Yang / Li, Yunfeng / Liu, Hao / Wang, Jinglei

    Plants (Basel, Switzerland)

    2024  Band 13, Heft 3

    Abstract: An appropriate water supply strategy is imperative for obtaining tomatoes of a high yield and quality; the lack of one has caused resource wastage and quality deterioration. To determine the suitable irrigation amount and simulate daily transpiration ... ...

    Abstract An appropriate water supply strategy is imperative for obtaining tomatoes of a high yield and quality; the lack of one has caused resource wastage and quality deterioration. To determine the suitable irrigation amount and simulate daily transpiration under these optimal irrigation conditions, a two-year greenhouse cultivation experiment was conducted over 2022-2023. Commencing at anthesis, three distinct irrigation gradients were triggered and designated as irrigation controls with the lower limits set at 80% (T1), 70% (T2), and 60% (T3) of the substrate water-holding capacity. We determined the optimal irrigation amount by ranking the treatments using the TOPSIS method, balancing the tomato yield and quality. A segmented daily transpiration model under optimal irrigation conditions driven by crop and environmental factors was established using the Marquardt method and data from 2022, and the model was validated using data from 2023. The results indicated that T2 was the optimal irrigation amount, with the water use efficiency increased by 18.0%, but with a 10.9% decrease in yield, while the quality indices improved significantly. The
    Sprache Englisch
    Erscheinungsdatum 2024-01-26
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13030374
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  8. Artikel: Spatial distribution dynamics for

    Li, Yunfeng / Wang, Yan / Du, Xiaojuan / Zhao, Chunying / He, Ping / Meng, Fanyun

    Ecology and evolution

    2024  Band 14, Heft 2, Seite(n) e11010

    Abstract: At different time scales, a species will experience diverse distribution changes. ... ...

    Abstract At different time scales, a species will experience diverse distribution changes. For
    Sprache Englisch
    Erscheinungsdatum 2024-02-21
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.11010
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  9. Artikel ; Online: Revealing the changes in signaling pathways caused by tofacitinib in patients with rheumatoid arthritis through RNA sequencing and the correlation with clinical parameters.

    Lu, Fangyi / Chen, Qilin / Qi, Xin / Cong, Menglin / Dai, Xinyue / Liu, Huaxiang / Li, Yunfeng

    Clinical rheumatology

    2024  Band 43, Heft 5, Seite(n) 1479–1489

    Abstract: Objectives: The current study is to accelerate the understanding of how tofacitinib works in patients with rheumatoid arthritis (RA) due to the lack of relevant information.: Method: We selected ten patients with active RA and obtained the expression ...

    Abstract Objectives: The current study is to accelerate the understanding of how tofacitinib works in patients with rheumatoid arthritis (RA) due to the lack of relevant information.
    Method: We selected ten patients with active RA and obtained the expression profile for their peripheral blood mononuclear cells before and after the tofacitinib treatment by RNA sequencing. The gene set enrichment analysis was conducted, and the significantly enriched gene sets were identified. The hub gene highly correlated with clinical parameters in the gene set was selected. We constructed the weighted gene co-expression network, linked modules with clinical indicators, and screened hub genes. The expression of representative hub genes was validated by real-time quantitative PCR (qPCR).
    Results: Gene set interferon (IFN) α and IFN β signaling was the most significantly down-regulated after tofacitinib treatment. In this gene set, genes Oas2 and Oasl showed a significant positive correlation with morning stiffness. In co-expression network, gene Vgll3 from the violet module with the highest correlation coefficient, was positively correlated with morning stiffness. Among them, Oasl and Vgll3 have shown significant down-regulation in qPCR validation.
    Conclusions: Our results highlighted the role of type I IFN, mainly including IFN α and IFN β, in the pathogenesis of RA and action for tofacitinib, and provided a new entry point for further elucidating the mechanism of morning stiffness. Key Points • Gene set IFN α and IFN β signaling was the most significantly down-regulated after tofacitinib treatment in RA patients. • Gene Oasl and Vgll3 were correlated with morning stiffness and significantly down-regulated due to the action of tofacitinib. • Type I IFN system was highlighted in the action of tofacitinib.
    Mesh-Begriff(e) Humans ; Leukocytes, Mononuclear/metabolism ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/genetics ; Arthritis, Rheumatoid/metabolism ; Signal Transduction ; Sequence Analysis, RNA ; Piperidines ; Pyrimidines
    Chemische Substanzen tofacitinib (87LA6FU830) ; Piperidines ; Pyrimidines
    Sprache Englisch
    Erscheinungsdatum 2024-03-16
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 604755-5
    ISSN 1434-9949 ; 0770-3198
    ISSN (online) 1434-9949
    ISSN 0770-3198
    DOI 10.1007/s10067-024-06931-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Editorial: Microbial interaction with banana: mechanisms, symbiosis, and integrated diseases control.

    Zheng, Si-Jun / Hu, Huigang / Li, Yunfeng / Chen, Jian / Li, Xundong / Bai, Tingting

    Frontiers in microbiology

    2024  Band 15, Seite(n) 1390969

    Sprache Englisch
    Erscheinungsdatum 2024-04-05
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2024.1390969
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