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  1. Artikel: Bank performance and its determinants in Korea/ Jeong Yeon Lee; Doyeon Kim

    Lee, Jeong Yeon / Kim, Doyeon

    Japan and the world economy : international journal of theory and policy Vol. 27 , p. 70-82

    2013  Band 27, Seite(n) 70–82

    Schlagwörter Bank ; Profitability ; Economies of scale ; Ownership structure ; Malmquist index
    Sprache Englisch
    Verlag Elsevier Science Publ
    Erscheinungsort Amsterdam
    Dokumenttyp Artikel
    ZDB-ID 649581-3
    ISSN 0922-1425
    Datenquelle ECONomics Information System

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  2. Artikel: Circuit Training Improves the Levels of β-Amyloid and Brain-Derived Neurotrophic Factor Related to Cognitive Impairment Risk Factors in Obese Elderly Korean Women.

    Kang, Duwang / Koh, Suhan / Kim, Taekyu / Bressel, Eadric / Kim, Doyeon

    Journal of clinical medicine

    2024  Band 13, Heft 3

    Abstract: ... ...

    Abstract Background
    Sprache Englisch
    Erscheinungsdatum 2024-01-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030799
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Genetic characteristics of a highly metastatic basal cell adenocarcinoma arising in buccal mucosa.

    Kim, DoYeon / Choi, KyungUn / Park, HaeRyoun / Song, JaeMin

    Oral oncology

    2024  Band 149, Seite(n) 106681

    Mesh-Begriff(e) Humans ; Mouth Mucosa/pathology ; Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Salivary Gland Neoplasms/genetics ; Salivary Gland Neoplasms/pathology
    Sprache Englisch
    Erscheinungsdatum 2024-01-05
    Erscheinungsland England
    Dokumenttyp Letter
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2023.106681
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 4869: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.A 456: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  4. Artikel ; Online: Sensitive detection of viable Cronobacter sakazakii by bioluminescent reporter phage emitting stable signals with truncated holin.

    Kim, Doyeon / Kim, Minsik

    Food research international (Ottawa, Ont.)

    2023  Band 174, Heft Pt 2, Seite(n) 113665

    Abstract: As outbreaks of foodborne illness caused by the opportunistic pathogen Cronobacter sakazakii (Cs) continue to occur, particularly in infants consuming powdered infant formula (PIF), the need for sensitive, rapid, and easy-to-use detection of Cs from food ...

    Abstract As outbreaks of foodborne illness caused by the opportunistic pathogen Cronobacter sakazakii (Cs) continue to occur, particularly in infants consuming powdered infant formula (PIF), the need for sensitive, rapid, and easy-to-use detection of Cs from food and food processing environments is increasing. Here, we developed bioluminescent reporter bacteriophages for viable Cs-specific, substrate-free, rapid detection by introducing luciferase and its corresponding substrate-providing enzyme complex into the virulent phage ΦC01. Although the reporter phage ΦC01_lux, constructed by replacing non-essential genes for phage infectivity with a luxCDABE reporter operon, produced bioluminescence upon Cs infection, the emitted signal was quickly decayed due to the superior bacteriolytic activity of ΦC01. By truncating the membrane pore-forming protein holin and thus limiting its function, the bacterial lysis was delayed and the resultant engineered reporter phage ΦC01_lux_Δhol could produce a more stable and reliable bioluminescent signal. Accordingly, ΦC01_lux_Δhol was able to detect at least an average of 2 CFU/ml of Cs artificially contaminated PIF and Sunsik and food contact surface models within a total of 7 h of assays, including 5 h of pre-enrichment for Cs amplification. The sensitive, easy-to-use, and specific detection of live Cs with the developed reporter phage could be applied as a novel complementary tool for monitoring Cs in food and food-related environments for food safety and public health.
    Mesh-Begriff(e) Cronobacter sakazakii/genetics ; Cronobacter sakazakii/isolation & purification ; Bacteriological Techniques/methods ; Bacteriophages/genetics ; Bacteriophages/metabolism ; Viral Proteins/genetics ; Viral Proteins/metabolism ; Food Microbiology/methods ; Genome, Viral/genetics ; Sequence Deletion ; Luminescent Measurements/methods ; Sensitivity and Specificity
    Chemische Substanzen Viral Proteins
    Sprache Englisch
    Erscheinungsdatum 2023-11-04
    Erscheinungsland Canada
    Dokumenttyp Journal Article
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2023.113665
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Effectiveness of Regular Aerobic Exercise in Improving Vascular Stiffness in Elderly Korean Women.

    Koh, Suhan / Kim, Taekyu / Kang, Duwang / Kim, Doyeon

    Journal of clinical medicine

    2023  Band 12, Heft 19

    Abstract: The purpose of this study was to determine the effects of aerobic exercise on carotid to femoral pulse wave velocity (cf-PWV), cell adhesion molecules (intracellular adhesion molecules (ICAM-1), vascular cell adhesion molecules (VCAM-1), endothelial ... ...

    Abstract The purpose of this study was to determine the effects of aerobic exercise on carotid to femoral pulse wave velocity (cf-PWV), cell adhesion molecules (intracellular adhesion molecules (ICAM-1), vascular cell adhesion molecules (VCAM-1), endothelial selectin (E-selectin), and oxidized LDL in elderly women aged 70-85 years, and to identify the effect of and correlation with vascular stiffness. Forty participants were recruited and divided into three groups; vascular stiffness (VSG,
    Sprache Englisch
    Erscheinungsdatum 2023-09-22
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12196119
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Public R&D Projects-Based Investment and Collaboration Framework for an Overarching South Korean National Strategy of Personalized Medicine

    Doyeon Lee / Keunhwan Kim

    International Journal of Environmental Research and Public Health, Vol 19, Iss 1291, p

    2022  Band 1291

    Abstract: Since the South Korean government designated personalized medicine (PM) as a national strategic task in 2016, it has spared no investment to achieve its goals, which were recently accelerated by the COVID-19 pandemic. This study analyzed investment ... ...

    Abstract Since the South Korean government designated personalized medicine (PM) as a national strategic task in 2016, it has spared no investment to achieve its goals, which were recently accelerated by the COVID-19 pandemic. This study analyzed investment trends in 17 regions and eight technology clusters related to PM, consisting of 5727 public R&D projects worth USD 148.5 million, from 2015 to 2020. We also illustrated the level of investment for different PM-related technology clusters in each region; various research organizations explicitly verified comparable innovation capabilities for all eight technology fields in 17 regions, showing individual differences in technology areas per region. Our framework provided information to allow implementation of two goals: administering successful PM and improving regional equality in public health and healthcare according to technical and organizational levels. This study empirically demonstrates that it can provide a precise overarching innovation scheme with regional, technical, and organizational dimensions to establish collaboration among different stakeholders, thereby creating a foundation for an overarching national PM strategy.
    Schlagwörter personalized medicine ; public R&D project ; government investment ; collaboration ; framework ; strategy ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: National Investment Framework for Revitalizing the R&D Collaborative Ecosystem of Sustainable Smart Agriculture

    Doyeon Lee / Keunhwan Kim

    Sustainability, Vol 14, Iss 6452, p

    2022  Band 6452

    Abstract: Demographic, economic, and environmental issues, including climate change events, aging population, growing urban-rural disparity, and the COVID-19 pandemic, contribute to vulnerabilities in agricultural production and food systems. South Korea has ... ...

    Abstract Demographic, economic, and environmental issues, including climate change events, aging population, growing urban-rural disparity, and the COVID-19 pandemic, contribute to vulnerabilities in agricultural production and food systems. South Korea has designated smart agriculture as a national strategic investment, expanding investment in research and development (R&D) to develop and commercialize convergence technologies, thus extending sustainable smart agriculture and strengthening global competitiveness. Hence, this study probes the status of smart agricultural R&D investment from the perspectives of public funds, research areas, technologies, regions, organizations, and stakeholders. It examines 5646 public R&D projects worth USD 1408.5 million on smart agriculture in 17 regions and eight technology clusters from 2015 to 2021. Further, it proposes a pool of potential collaborative networks via a case study of strawberry, a representative veritable crop inspiring smart agriculture, to demonstrate the study framework’s usefulness in promoting smart agriculture and establishing a sustainable R&D collaboration ecosystem. The proposed framework, accordingly, allows stakeholders to understand and monitor the status of R&D investment from various perspectives. Moreover, given the insight into the tasks belonging to technical areas and regions that require sustainable cooperation in smart agriculture, central and local governments develop policies to reinforce sustainable smart-farming models.
    Schlagwörter smart agriculture ; collaboration ; national R&D project ; government investment ; framework ; ecosystem ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 333
    Sprache Englisch
    Erscheinungsdatum 2022-05-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: SCD and MTHFD2 inhibitors for high-risk acute myeloid leukaemia patients, as suggested by ELN2017-pathway association.

    Kim, Han Sun / Kim, Doyeon / Kim, Jiwoo / Park, Sunghyouk / de Guzman, Arvie Camille V

    Clinical and translational medicine

    2023  Band 13, Heft 7, Seite(n) e1311

    Mesh-Begriff(e) Humans ; Leukemia, Myeloid, Acute/drug therapy
    Sprache Englisch
    Erscheinungsdatum 2023-07-26
    Erscheinungsland United States
    Dokumenttyp Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2697013-2
    ISSN 2001-1326 ; 2001-1326
    ISSN (online) 2001-1326
    ISSN 2001-1326
    DOI 10.1002/ctm2.1311
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: The application of adaptively evolved thermostable bacteriophage ΦYMFM0293 to control Salmonella spp. in poultry skin.

    Lee, Jieon / Kim, Doyeon / Kim, Minsik

    Food research international (Ottawa, Ont.)

    2023  Band 167, Seite(n) 112665

    Abstract: Bacteriophages, bacterial viruses, are now being re-highlighted as one of the promising alternative antimicrobial agents to control bacterial pathogens in various fields, including the food industry. However, wild-type (WT) phages isolated from nature ... ...

    Abstract Bacteriophages, bacterial viruses, are now being re-highlighted as one of the promising alternative antimicrobial agents to control bacterial pathogens in various fields, including the food industry. However, wild-type (WT) phages isolated from nature are vulnerable to external stresses such as heat, limiting the usability of phages in thermal processing. Here, we applied an adaptive laboratory evolution approach to improving the heat stability of newly isolated Salmonella-infecting lytic phage ΦYMFM0293 and examined its application in the poultry scalding process. After 15 cycles of exposure to sub-lethal temperature, the obtained adaptively evolved (AE) phages maintained approximately 3-log more infectious particles at 73 or 74 °C than the WT and non-heat-treated control phages. Missense mutations mainly concentrated in the genes related to the phage tail module were identified from the independently obtained heat-challenged phages, regardless of host Salmonella's heat-shock protein chaperone induction. These results demonstrated the necessity and sufficiency of the phage exposures to heat for thermal adaptation and suggested the involvement of the phage tail in heat stability. No significant physiological or morphological changes except the mutually offsetting phage replication parameters were observed in the AE phages. Accordingly, hot water supplemented with the AE phages significantly reduced the number of artificially contaminated Salmonella cells on chicken and duck skin in the mimicked scalding process. The AE strategy used here could be applied to other WT phages to improve their usability as more feasible antimicrobials for food safety.
    Mesh-Begriff(e) Animals ; Bacteriophages/genetics ; Poultry ; Salmonella ; Chickens ; Food Safety/methods ; Anti-Infective Agents
    Chemische Substanzen Anti-Infective Agents
    Sprache Englisch
    Erscheinungsdatum 2023-03-09
    Erscheinungsland Canada
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1111695-x
    ISSN 1873-7145 ; 0963-9969
    ISSN (online) 1873-7145
    ISSN 0963-9969
    DOI 10.1016/j.foodres.2023.112665
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Bonn

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  10. Artikel ; Online: Public R&D Projects-Based Investment and Collaboration Framework for an Overarching South Korean National Strategy of Personalized Medicine.

    Lee, Doyeon / Kim, Keunhwan

    International journal of environmental research and public health

    2022  Band 19, Heft 3

    Abstract: Since the South Korean government designated personalized medicine (PM) as a national strategic task in 2016, it has spared no investment to achieve its goals, which were recently accelerated by the COVID-19 pandemic. This study analyzed investment ... ...

    Abstract Since the South Korean government designated personalized medicine (PM) as a national strategic task in 2016, it has spared no investment to achieve its goals, which were recently accelerated by the COVID-19 pandemic. This study analyzed investment trends in 17 regions and eight technology clusters related to PM, consisting of 5727 public R&D projects worth USD 148.5 million, from 2015 to 2020. We also illustrated the level of investment for different PM-related technology clusters in each region; various research organizations explicitly verified comparable innovation capabilities for all eight technology fields in 17 regions, showing individual differences in technology areas per region. Our framework provided information to allow implementation of two goals: administering successful PM and improving regional equality in public health and healthcare according to technical and organizational levels. This study empirically demonstrates that it can provide a precise overarching innovation scheme with regional, technical, and organizational dimensions to establish collaboration among different stakeholders, thereby creating a foundation for an overarching national PM strategy.
    Mesh-Begriff(e) COVID-19 ; Humans ; Pandemics ; Precision Medicine ; Republic of Korea ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2022-01-24
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19031291
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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