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  1. Artikel: Concurrent Xanthogranulomatous Pyelonephritis and Upper Urinary Tract Transitional Cell Carcinoma.

    Guglin, Anthony / Weiss, Robert / Singh, Adityabikram / Mittal, Anugya / Hwang, Thomas / Shah, Ankit

    Case reports in urology

    2023  Band 2023, Seite(n) 6021178

    Abstract: A 37-year-old male with a history of chronic nephrolithiasis presented to the ED with gross hematuria, clot retention, and right flank pain. The patient had radiological findings of perinephric stranding, marked hydronephrosis, and marked thinning of the ...

    Abstract A 37-year-old male with a history of chronic nephrolithiasis presented to the ED with gross hematuria, clot retention, and right flank pain. The patient had radiological findings of perinephric stranding, marked hydronephrosis, and marked thinning of the right renal parenchyma on computed tomography (CT), all suggestive of xanthogranulomatous pyelonephritis (XGP). The specimen following radical nephrectomy revealed urothelial carcinoma (UC) in a background of XGP but with no evidence of spread to regional lymph nodes. Follow-up imaging revealed hypodense lesions in the liver which demonstrated UC on biopsy. This is the first reported case of a young patient presenting with such an advanced stage of UC in the setting of XGP. It illustrates the link between inflammatory processes of the kidney and malignancy of the upper urinary tract.
    Sprache Englisch
    Erscheinungsdatum 2023-03-31
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2627659-8
    ISSN 2090-6978 ; 2090-696X
    ISSN (online) 2090-6978
    ISSN 2090-696X
    DOI 10.1155/2023/6021178
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Recognition and treatment of devastating vasculopathic systemic disorders: Coronavirus disease 2019 and rickettsioses.

    Mittal, Anugya / Elias, Marcus L / Schwartz, Robert A / Kapila, Rajendra

    Dermatologic therapy

    2021  Band 34, Heft 4, Seite(n) e14984

    Abstract: Cutaneous involvement can be an important sign of both COVID-19 and rickettsioses. Rickettsial infections may be first evident as an exanthem with eschars as a key finding. In contrast, eschars and necrotic lesions can be seen in critically ill COVID-19 ... ...

    Abstract Cutaneous involvement can be an important sign of both COVID-19 and rickettsioses. Rickettsial infections may be first evident as an exanthem with eschars as a key finding. In contrast, eschars and necrotic lesions can be seen in critically ill COVID-19 patients. Both illnesses share a similar mechanism of infecting endothelial cells resulting in vasculopathy. Rickettsia parkeri and Rickettsia 364D are both characterized by eschars unlike Rickettsia rickettsii. Other eschar causing rickettsioses such as Rickettsia conorii, Rickettsia africae, and Orientia tsutsugamushi are commonly diagnosed in people from or having traveled through endemic areas. While there is no consensus on treatment for COVID-19, rickettsioses are treatable. Due to possibly serious consequences of delayed treatment, doxycycline should be administered given an eschar-presenting patient's travel history and sufficient suspicion of vector exposure. The proliferation of COVID-19 cases has rendered it critical to differentiate between the two, both of which may have overlapping vasculopathic cutaneous findings. We review these diseases, emphasizing the importance of cutaneous involvement, while also discussing possible therapeutic interventions.
    Mesh-Begriff(e) COVID-19 ; Endothelial Cells ; Humans ; Rickettsia ; Rickettsia Infections/diagnosis ; Rickettsia Infections/drug therapy ; SARS-CoV-2
    Sprache Englisch
    Erscheinungsdatum 2021-05-29
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14984
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Association studies of Toll-like receptor gene polymorphisms with allograft survival in renal transplant recipients of North India.

    Srivastava, Priyanka / Singh, Anugya / Kesarwani, Praveen / Jaiswal, Praveen K / Singh, Vibha / Mittal, Rama D

    Clinical transplantation

    2012  Band 26, Heft 4, Seite(n) 581–588

    Abstract: Organ transplantation itself inevitably activates the innate immune system by Toll-like receptors (TLRs), potentially leading to allograft rejection and graft failure. We evaluated the possible association of TLR2, TLR3, and TLR9 polymorphisms of donor- ... ...

    Abstract Organ transplantation itself inevitably activates the innate immune system by Toll-like receptors (TLRs), potentially leading to allograft rejection and graft failure. We evaluated the possible association of TLR2, TLR3, and TLR9 polymorphisms of donor-recipient pairs and acute rejection in renal transplant patients of North India. TLR2 (-196 to -174 del), TLR3 (c.1377C/T; rs 3775290), and TLR9 (+2848 G/A; rs 352140) were genotyped using DNA samples from 200 donor-recipient pairs of live donor kidney transplantation by applying Restriction Fragment Length Polymorphism (RFLP) methodology. The variant allele frequency of TLR2 (-196 to -174 del) was significantly different between recipients and donors (7.5% vs. 5.0%; p = 0.049; OR = 3.9; 95% CI = 1.01-15.32). However, no significant association for allograft rejection was observed in transplant recipients for TLR3 and TLR9. Interestingly, a low prevalence of AA genotype of TLR9 + 2848 G>A was observed in rejecters when compared with non-rejecters, demonstrating protective association with allograft rejection (OR = 0.30, 95% CI = 0.12-0.88, p = 0.028). An allele in patients was also observed to be associated with higher rejection-free survival (log-rank = 0.044). These TLR gene polymorphisms, upon further evaluation, may be helpful in elucidation of immunobiological mechanisms associated with renal graft rejection.
    Mesh-Begriff(e) Adolescent ; Adult ; Child ; Female ; Follow-Up Studies ; Graft Rejection/genetics ; Graft Rejection/mortality ; Graft Survival/genetics ; Humans ; Kidney Transplantation/mortality ; Male ; Middle Aged ; Polymerase Chain Reaction ; Polymorphism, Genetic/genetics ; Polymorphism, Restriction Fragment Length ; Prognosis ; Survival Rate ; Tissue Donors ; Toll-Like Receptor 2/genetics ; Toll-Like Receptor 3/genetics ; Toll-Like Receptor 9/genetics ; Transplantation, Homologous ; Young Adult
    Chemische Substanzen TLR2 protein, human ; TLR3 protein, human ; TLR9 protein, human ; Toll-Like Receptor 2 ; Toll-Like Receptor 3 ; Toll-Like Receptor 9
    Sprache Englisch
    Erscheinungsdatum 2012-07
    Erscheinungsland Denmark
    Dokumenttyp Comparative Study ; Journal Article
    ZDB-ID 639001-8
    ISSN 1399-0012 ; 0902-0063
    ISSN (online) 1399-0012
    ISSN 0902-0063
    DOI 10.1111/j.1399-0012.2011.01577.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Contamination of Drinking Water Due to Coal-Based Thermal Power Plants in India

    Agrawal, Prashant / Mittal, Anugya / Prakash, Rajiv / Kumar, Manoj / Tripathi, S. K

    Environmental forensics. 2011 Mar. 15, v. 12, no. 1

    2011  

    Abstract: This study assessed the impact of an Anpara and Renusgar coal-based thermal power plants on drinking water sources. In this work, the concentration of trace metals such as Pb, Cd, Ni, and As in groundwater samples obtained from hand pumps located near ... ...

    Abstract This study assessed the impact of an Anpara and Renusgar coal-based thermal power plants on drinking water sources. In this work, the concentration of trace metals such as Pb, Cd, Ni, and As in groundwater samples obtained from hand pumps located near these power plants were measured. The concentration levels of all the studied heavy metals in groundwater were found to be higher than the maximum acceptable limits of World Health Organization for drinking water.
    Schlagwörter World Health Organization ; arsenic ; cadmium ; drinking water ; groundwater ; heavy metals ; lead ; nickel ; power plants ; pumps ; India
    Sprache Englisch
    Erscheinungsverlauf 2011-0315
    Umfang p. 92-97.
    Erscheinungsort Taylor & Francis Group
    Dokumenttyp Artikel
    ISSN 1527-5930
    DOI 10.1080/15275922.2011.547437
    Datenquelle NAL Katalog (AGRICOLA)

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  5. Artikel ; Online: Assessment of contamination of soil due to heavy metals around coal fired thermal power plants at Singrauli region of India.

    Agrawal, Prashant / Mittal, Anugya / Prakash, Rajiv / Kumar, Manoj / Singh, T B / Tripathi, S K

    Bulletin of environmental contamination and toxicology

    2010  Band 85, Heft 2, Seite(n) 219–223

    Abstract: In the present study, an attempt was made to measure contamination of soil around four large coal-based Thermal Power Plants. The concentration of Cadmium, Lead, Arsenic and Nickel was estimated in all four directions from Thermal Power Plants. The soil ... ...

    Abstract In the present study, an attempt was made to measure contamination of soil around four large coal-based Thermal Power Plants. The concentration of Cadmium, Lead, Arsenic and Nickel was estimated in all four directions from Thermal Power Plants. The soil in the study area was found to be contaminated to varying degrees from coal combustion byproducts. The soil drawn from various selected sites in each direction was largely contaminated by metals, predominantly higher within 2-4 km distance from Thermal Power Plant. Within 2-4 km, the mean maximum concentration of Cadmium, Lead, Arsenic and Nickel was 0.69, 13.69, 17.76, and 3.51 mg/kg, respectively. It was also observed that concentration was maximum in the prevalent wind direction. The concentration of Cadmium, Lead, Arsenic and Nickel was highest 0.69, 13.23, 17.29 and 3.56 mg/kg, respectively in west direction where wind was prevalent.
    Mesh-Begriff(e) Environmental Monitoring ; India ; Industrial Waste/analysis ; Metals, Heavy/analysis ; Power Plants ; Soil/analysis ; Soil Pollutants/analysis
    Chemische Substanzen Industrial Waste ; Metals, Heavy ; Soil ; Soil Pollutants
    Sprache Englisch
    Erscheinungsdatum 2010-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 6895-0
    ISSN 1432-0800 ; 0007-4861
    ISSN (online) 1432-0800
    ISSN 0007-4861
    DOI 10.1007/s00128-010-0043-8
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Assessment of Contamination of Soil due to Heavy Metals around Coal Fired Thermal Power Plants at Singrauli Region of India

    Agrawal, Prashant / Mittal, Anugya / Prakash, Rajiv / Kumar, Manoj / Singh, T. B / Tripathi, S. K

    Bulletin of environmental contamination and toxicology. 2010 Aug., v. 85, no. 2

    2010  

    Abstract: In the present study, an attempt was made to measure contamination of soil around four large coal-based Thermal Power Plants. The concentration of Cadmium, Lead, Arsenic and Nickel was estimated in all four directions from Thermal Power Plants. The soil ... ...

    Abstract In the present study, an attempt was made to measure contamination of soil around four large coal-based Thermal Power Plants. The concentration of Cadmium, Lead, Arsenic and Nickel was estimated in all four directions from Thermal Power Plants. The soil in the study area was found to be contaminated to varying degrees from coal combustion byproducts. The soil drawn from various selected sites in each direction was largely contaminated by metals, predominantly higher within 2-4 km distance from Thermal Power Plant. Within 2-4 km, the mean maximum concentration of Cadmium, Lead, Arsenic and Nickel was 0.69, 13.69, 17.76, and 3.51 mg/kg, respectively. It was also observed that concentration was maximum in the prevalent wind direction. The concentration of Cadmium, Lead, Arsenic and Nickel was highest 0.69, 13.23, 17.29 and 3.56 mg/kg, respectively in west direction where wind was prevalent.
    Schlagwörter fly ash ; soil
    Sprache Englisch
    Erscheinungsverlauf 2010-08
    Umfang p. 219-223.
    Verlag Springer-Verlag
    Erscheinungsort New York
    Dokumenttyp Artikel
    ZDB-ID 6895-0
    ISSN 1432-0800 ; 0007-4861
    ISSN (online) 1432-0800
    ISSN 0007-4861
    DOI 10.1007/s00128-010-0043-8
    Datenquelle NAL Katalog (AGRICOLA)

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