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  1. Artikel ; Online: Health Insurance For People Younger Than Age 65: Expiration Of Temporary Policies Projected To Reshuffle Coverage, 2023-33.

    Hanson, Caroline / Hou, Claire / Percy, Allison / Vreeland, Emily / Minicozzi, Alexandra

    Health affairs (Project Hope)

    2023  Band 42, Heft 6, Seite(n) 742–752

    Abstract: The Congressional Budget Office estimates that in 2023, 248 million people in the US who are younger than age sixty-five have health insurance coverage (mostly through employment-based plans), and twenty-three million people, or 8.3 percent of that age ... ...

    Abstract The Congressional Budget Office estimates that in 2023, 248 million people in the US who are younger than age sixty-five have health insurance coverage (mostly through employment-based plans), and twenty-three million people, or 8.3 percent of that age group, are uninsured-with significant variations in coverage by income and, to a lesser extent, by race and ethnicity. The unprecedented low uninsurance rate is largely attributable to temporary policies that kept beneficiaries enrolled in Medicaid and enhanced the subsidies available through the health insurance Marketplaces during the COVID-19 pandemic. As the continuous eligibility provisions unwind in 2023 and 2024, an estimated 9.3 million people in that age group will transition to other forms of coverage, and 6.2 million will become uninsured. If the enhanced subsidies expire after 2025, 4.9 million fewer people are estimated to enroll in Marketplace coverage, instead enrolling in unsubsidized nongroup or employment-based coverage or becoming uninsured. By 2033 the uninsurance rate is projected to be 10.1 percent, which is still below the 2019 rate of about 12 percent.
    Mesh-Begriff(e) United States ; Humans ; Aged ; Pandemics ; Insurance Coverage ; COVID-19 ; Insurance, Health ; Medicaid ; Medically Uninsured ; Policy
    Sprache Englisch
    Erscheinungsdatum 2023-05-24
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 632712-6
    ISSN 1544-5208 ; 0278-2715
    ISSN (online) 1544-5208
    ISSN 0278-2715
    DOI 10.1377/hlthaff.2023.00325
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Let me pay taxes!

    Minicozzi, Alessia

    Narrative inquiry in bioethics

    2013  Band 3, Heft 3, Seite(n) 210–213

    Mesh-Begriff(e) Attitude ; Disabled Persons ; Employment ; Humans
    Sprache Englisch
    Erscheinungsdatum 2013
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2632728-4
    ISSN 2157-1740 ; 2157-1732
    ISSN (online) 2157-1740
    ISSN 2157-1732
    DOI 10.1353/nib.2013.0081
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Ensuring no patient is lost along the way - a single-centre experience of the clinical genetics referral pathways for Lynch syndrome.

    El-Shakankery, Karim Hussien / Balogh, Petra / Grantham, Marianne / Minicozzi, Anna / Diamantis, Nikolaos

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2023  Band 25, Heft 5, Seite(n) 838–842

    Abstract: Lynch syndrome (LS), caused by heterozygous germline mutation in one of the key mismatch repair (MMR) genes, is the primary cause of inherited colorectal cancer (CRC). LS also increases susceptibility to several other cancers. It is estimated that just 5% ...

    Abstract Lynch syndrome (LS), caused by heterozygous germline mutation in one of the key mismatch repair (MMR) genes, is the primary cause of inherited colorectal cancer (CRC). LS also increases susceptibility to several other cancers. It is estimated that just 5% of patients with LS are aware of their diagnosis. Therefore, in an attempt to increase the identification of cases within the UK population, the 2017 NICE guidelines recommend offering immunohistochemistry for MMR proteins or microsatellite instability (MSI) testing to all people with CRC when first diagnosed. Following identification of MMR deficiency, eligible patients should be assessed for underlying causes, including potential referral to the genetics service and/or germline LS testing (if appropriate). In our regional centre for CRC, we audited local pathways to identify what proportion of patients are being correctly referred, in line with national guidelines. Reflecting on these results, we highlight our practical concerns by identifying the pitfalls and issues faced with the recommended referral pathway. We also propose possible solutions to improve the efficacy of the system for both referrers and patients. Finally, we discuss the ongoing interventions that national bodies and regional centres are implementing to improve and further streamline this process.
    Mesh-Begriff(e) Humans ; Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis ; Colorectal Neoplasms, Hereditary Nonpolyposis/genetics ; Colorectal Neoplasms/genetics ; Neoplastic Syndromes, Hereditary ; Microsatellite Instability ; Germ-Line Mutation ; DNA Mismatch Repair/genetics
    Sprache Englisch
    Erscheinungsdatum 2023-02-15
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16496
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Transition to adult care: another view.

    Minicozzi, A

    Pediatric nursing

    2000  Band 26, Heft 4, Seite(n) 411–412

    Mesh-Begriff(e) Adaptation, Psychological ; Adolescent ; Adult ; Autobiography as Topic ; Child ; Female ; Humans ; Long-Term Care/psychology ; Nurse's Role ; Patient Care Team ; Patient Transfer ; Sick Role ; Spinal Muscular Atrophies of Childhood/nursing ; Spinal Muscular Atrophies of Childhood/psychology
    Sprache Englisch
    Erscheinungsdatum 2000-07
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 752968-5
    ISSN 0097-9805
    ISSN 0097-9805
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease.

    Humphreys, David T / Lewis, Amy / Pan-Castillo, Belen / Berti, Giulio / Mein, Charles / Wozniak, Eva / Gordon, Hannah / Gadhok, Radha / Minicozzi, Annamaria / ChinAleong, Joanna / Feakins, Roger / Giannoulatou, Eleni / James, Louisa K / Stagg, Andrew J / Lindsay, James Oliver / Silver, Andrew

    Journal of cellular and molecular medicine

    2024  Band 28, Heft 9, Seite(n) e18344

    Abstract: Single cell RNA sequencing of human full thickness Crohn's disease (CD) small bowel resection specimens was used to identify potential therapeutic targets for stricturing (S) CD. Using an unbiased approach, 16 cell lineages were assigned within 14,539 ... ...

    Abstract Single cell RNA sequencing of human full thickness Crohn's disease (CD) small bowel resection specimens was used to identify potential therapeutic targets for stricturing (S) CD. Using an unbiased approach, 16 cell lineages were assigned within 14,539 sequenced cells from patient-matched SCD and non-stricturing (NSCD) preparations. SCD and NSCD contained identical cell types. Amongst immune cells, B cells and plasma cells were selectively increased in SCD samples. B cell subsets suggested formation of tertiary lymphoid tissue in SCD and compared with NSCD there was an increase in IgG, and a decrease in IgA plasma cells, consistent with their potential role in CD fibrosis. Two Lumican-positive fibroblast subtypes were identified and subclassified based on expression of selectively enriched genes as fibroblast clusters (C) 12 and C9. Cells within these clusters expressed the profibrotic genes Decorin (C12) and JUN (C9). C9 cells expressed ACTA2; ECM genes COL4A1, COL4A2, COL15A1, COL6A3, COL18A1 and ADAMDEC1; LAMB1 and GREM1. GO and KEGG Biological terms showed extracellular matrix and stricture organization associated with C12 and C9, and regulation of WNT pathway genes with C9. Trajectory and differential gene analysis of C12 and C9 identified four sub-clusters. Intra sub-cluster gene analysis detected 13 co-regulated gene modules that aligned along predicted pseudotime trajectories. CXCL14 and ADAMDEC1 were key markers in module 1. Our findings support further investigation of fibroblast heterogeneity and interactions with local and circulating immune cells at earlier time points in fibrosis progression. Breaking these interactions by targeting one or other population may improve therapeutic management for SCD.
    Mesh-Begriff(e) Humans ; Crohn Disease/genetics ; Crohn Disease/pathology ; Crohn Disease/metabolism ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Single-Cell Analysis/methods ; B-Lymphocytes/metabolism ; B-Lymphocytes/immunology ; B-Lymphocytes/pathology ; Male ; Female ; Adult ; Gene Expression Profiling
    Sprache Englisch
    Erscheinungsdatum 2024-04-11
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2074559-X
    ISSN 1582-4934 ; 1582-4934 ; 1582-1838
    ISSN (online) 1582-4934
    ISSN 1582-4934 ; 1582-1838
    DOI 10.1111/jcmm.18344
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Medical savings accounts: what story do the data tell?

    Minicozzi, Alexandra

    Health affairs (Project Hope)

    2006  Band 25, Heft 1, Seite(n) 256–267

    Abstract: Fewer than a quarter-million tax units had reported a medical savings account (MSA) by the end of 2001. Nearly one-quarter of those having an MSA reported being previously uninsured. The tax data support the prediction that higher-income taxpayers are ... ...

    Abstract Fewer than a quarter-million tax units had reported a medical savings account (MSA) by the end of 2001. Nearly one-quarter of those having an MSA reported being previously uninsured. The tax data support the prediction that higher-income taxpayers are more likely than others to be MSA consumers. Surprisingly, the middle-aged had the greatest predicted MSA demand, even after income and marginal tax rate were controlled for. There is mixed evidence as to whether the account was treated as a savings vehicle. For those who continued their accounts, their build-up was generally sufficient to offset a year or two of future medical expenses below the deductible.
    Mesh-Begriff(e) Humans ; Income Tax/statistics & numerical data ; Medical Savings Accounts/trends ; Medical Savings Accounts/utilization ; Middle Aged ; Social Class ; United States
    Sprache Englisch
    Erscheinungsdatum 2006-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 632712-6
    ISSN 1544-5208 ; 0278-2715
    ISSN (online) 1544-5208
    ISSN 0278-2715
    DOI 10.1377/hlthaff.25.1.256
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Management of distal rectal cancer: results from a national survey.

    Melotti, G / De Antoni, E / Habr-Gama, A / Minicozzi, A

    Updates in surgery

    2013  Band 65, Heft 1, Seite(n) 43–52

    Abstract: Owing to the complexity of distal rectal cancer its management requires a multidisciplinary approach. The diagnosis and the response after neoadjuvant chemoradiotherapy are not easy to assess and therefore the surgical approach is heterogeneous. The ... ...

    Abstract Owing to the complexity of distal rectal cancer its management requires a multidisciplinary approach. The diagnosis and the response after neoadjuvant chemoradiotherapy are not easy to assess and therefore the surgical approach is heterogeneous. The purpose of this survey is to evaluate the experiences of members of the Italian Society of Surgery in diagnosis and treatment strategies for rectal cancer and compare it with international practice. A questionnaire was devised comprising 18 questions with 11 sub-items making a total of 29 questions and submitted online to all the 2,500 members of the SIC starting from July 2010. The survey was completed in June 2011. The overall response rate was 17.8 % (444). The majority of the Italian surgeons' responses were in line with the international consensus reflecting the complex management of distal rectal cancer. Other opinions, especially those on staging, diverge from the common view of MRI being the gold standard in the assessment of loco-regional diffusion of the disease and on the superiority of FDG PET-CT versus CT for systemic staging. The timing for the re-staging and for surgery following neoadjuvant chemoradiotherapy does not reflect the international opinion. Italian surgeons are also exposed to the common difficulties encountered internationally in the management of distal rectal cancer. Probably, the implementation of an Italian rectal cancer registry and of many national and international multicentre studies may improve the management of rectal cancer in Italy.
    Mesh-Begriff(e) Humans ; Italy ; Practice Patterns, Physicians' ; Rectal Neoplasms/pathology ; Rectal Neoplasms/therapy ; Surveys and Questionnaires ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2013-01-19
    Erscheinungsland Italy
    Dokumenttyp Journal Article
    ZDB-ID 2572692-4
    ISSN 2038-3312 ; 2038-131X
    ISSN (online) 2038-3312
    ISSN 2038-131X
    DOI 10.1007/s13304-012-0192-x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: New method for internal anal sphincter measurements: feasibility study.

    Sboarina, A / Minicozzi, A / Cordiano, C

    International journal of computer assisted radiology and surgery

    2010  Band 5, Heft 5, Seite(n) 515–525

    Abstract: Purpose: The aim of this paper is to provide a method for measuring the internal anal sphincter on the basis of the quantitative analysis of three-dimensional endosonographic images. A software calculates a large set of measurements which are able to ... ...

    Abstract Purpose: The aim of this paper is to provide a method for measuring the internal anal sphincter on the basis of the quantitative analysis of three-dimensional endosonographic images. A software calculates a large set of measurements which are able to describe the three-dimensional shape of the muscle.
    Methods: A software provides four types of measurements: thickness, length, area and volume. The different magnitudes are estimated using the same reference system. The measurements obtained are modeled by functions that describe their spatial trend. The precision and reproducibility of the method was tested on a phantom before a study was performed on fifteen healthy patients. The measurements were carried out by two different operators. The inter-observer variability were assessed.
    Results: In the phantom measurements the mean errors and the standard deviation were: 0.05 +/- 0.1 mm for the thickness, 0.02 +/- 0.12 mm for the length, -4.43 +/- 2.4 mm(2) for the area, -20.69 +/- 20.83 mm(3) for the volume. The maximum absolute differences between the measurements carried out by the two operators was: 0.18 mm for the thickness (in the 95% of the case), 1.69 mm(2) for the area (in the 95% of the case), and 0.25 mm for the length, and 29.46 mm(3) for the volume. The human IAS assessments were evaluated on each segment. The mean of the all tissue measurements carried out were (mean +/- SD): 1.71 +/- 0.34 mm for the thickness, 33.24 +/- 6.10 mm for the length, 111.28 +/- 29.08 mm(2) for the area. The mean of the volume measurements of the entire tissue was: 4124 +/- 1160 mm(3). Inter-observer variability was observed only in the anterior proximal segment for the thickness measurements by Wilcoxon's signed rank test (P value = 0.048) and for the volume assessments by the limits of agreement method (-118 to 78 mm(3)). The mean percentage errors and the limit of agreement for the measurements of the entire tissue were: 0.27 and (-0.11 to 0.12 mm) for the thickness, -2.32 and (-3.88 to 2.33 mm) for the length, -0.05 and (-9.71 to 9.83 mm(2)) for the area, -1.89 and (-366 to 240 mm(3)) for the volume.
    Conclusion: The assessments of accuracy and precision of the method result satisfactory for all four type of measurements. The reproducibility analysis confirms very good inter-observer agreement for the phantom measurements and for the most part of the IAS segments evaluations. Inter-observer variability was seen only for the thickness and volume measurements of the anterior-proximal segment. Our method provides a high number of measurements with good accuracy enabling a very detailed study of IAS morphology.
    Mesh-Begriff(e) Anal Canal/diagnostic imaging ; Endosonography/methods ; Feasibility Studies ; Humans ; Imaging, Three-Dimensional ; Phantoms, Imaging ; Reproducibility of Results
    Sprache Englisch
    Erscheinungsdatum 2010-02-24
    Erscheinungsland Germany
    Dokumenttyp Comparative Study ; Journal Article
    ZDB-ID 2365628-1
    ISSN 1861-6429 ; 1861-6410
    ISSN (online) 1861-6429
    ISSN 1861-6410
    DOI 10.1007/s11548-010-0406-y
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Buch ; Dissertation / Habilitation: Baby doctors

    Minicozzi, Alessia

    the socialization and the bioethics of the first-year attending

    2006  

    Verfasserangabe Alessia Minicozzi
    Mesh-Begriff(e) Medical Staff, Hospital/psychology ; Medical Staff, Hospital/ethics ; Socialization ; Professional Autonomy
    Schlagwörter United States
    Sprache Englisch
    Umfang v, 146 p.
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Thesis (Ph. D.)--University of Pennsylvania, 2006
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  10. Artikel: The short term effect of educational debt on job decisions

    Minicozzi, Alexandra

    Economics of education review Vol. 24, No. 4 , p. 417-430

    2005  Band 24, Heft 4, Seite(n) 417–430

    Verfasserangabe Alexandra Minicozzi
    Schlagwörter Studienfinanzierung ; Bildungsertrag ; USA
    Sprache Englisch
    Umfang graph. Darst.
    Verlag Elsevier Science
    Erscheinungsort Amsterdam [u.a.]
    Dokumenttyp Artikel
    ZDB-ID 865180-2
    Datenquelle ECONomics Information System

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