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  1. Buch ; Online: Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment

    Zhang, Huijie

    2023  

    Schlagwörter Medicine ; Pharmacology ; graphene quantum dot ; targeted drug delivery ; photothermal therapy ; chemo-therapy ; polymeric prodrug ; theranostic nanocomplex ; pH-triggering releasing ; magnetic targeting ; magnetic hyperthermia ; magnetic resonance imaging ; docetaxel ; adenosine receptors ; PLGA ; nanoparticles ; lung cancer ; Notch signaling ; RBPJ protein ; drug repurposing ; fidaxomicin ; acarbose ; schaftoside ; breast cancer ; experimental skin cancer ; entrapment efficacy ; ethosomes ; metformin ; in vitro permeation ; zeta potential ; sesamol ; albumin nanoparticles ; doxorubicin ; oxidative stress ; antioxidants ; tumor-derived membrane vesicles ; cancer therapy ; tumor vaccine ; personalized immunotherapy ; low-density lipoprotein ; nanoparticle ; tumor microenvironment-responsive ; magnetic nanofluid ; improved magnetic resonance imaging ; neutral-responsive Fenton reaction ; enhanced chemodynamic therapy ; brain targeting ; folate receptor ; glioma cancer ; erlotinib ; blood-brain barrier
    Sprache Englisch
    Umfang 1 electronic resource (212 pages)
    Verlag MDPI - Multidisciplinary Digital Publishing Institute
    Erscheinungsort Basel
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030375513
    ISBN 9783036570402 ; 3036570403
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  2. Buch ; Online ; E-Book: Analyzing high-dimensional gene expression and DNA methylation data with R

    Zhang, Hongmei

    (Chapman & Hall/CRC computational biology series)

    2020  

    Verfasserangabe Hongmei Zhang
    Serientitel Chapman & Hall/CRC computational biology series
    Schlagwörter Gene expression/Statistical methods ; Gene expression/Data processing ; DNA/Methylation ; Epigenetics/Statistical methods ; R (Computer program language)
    Thema/Rubrik (Code) 572.865015195
    Sprache Englisch
    Umfang 1 Online-Ressource (xii, 190 Seiten), Illustrationen, Diagramme
    Ausgabenhinweis First edition
    Verlag CRC Press, Taylor & Francis Group
    Erscheinungsort Boca Raton
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020472824
    ISBN 978-0-429-15519-2 ; 9781498772594 ; 9780367495169 ; 0-429-15519-0 ; 1498772595 ; 0367495163
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  3. Artikel: Physicochemical properties of vitreous and floury endosperm flours in maize

    Zhang, Haiyan

    Food Science & Nutrition, 7(8):2605-2612

    2019  

    Abstract: Three maize cultivars with different endosperm types (flint, semiflint, and dent maize cultivars) were studied to characterize vitreous endosperm flour properties compared with those of floury endosperm flour from the same maize kernels. Vitreous ... ...

    Abstract Three maize cultivars with different endosperm types (flint, semiflint, and dent maize cultivars) were studied to characterize vitreous endosperm flour properties compared with those of floury endosperm flour from the same maize kernels. Vitreous endosperm flour had higher amylose and protein contents, and lower starch content, higher percentage of large starch granule, bigger mean diameter of starch granule, higher iodine capacity, higher trough viscosity and final viscosity and setback, lower swelling power, lower peak viscosity and breakdown, and higher peak time and pasting temperature than the counterpart floury endosperm flour. X‐ray diffraction analysis indicated typical A‐pattern for starches of vitreous and floury endosperm flours. Floury endosperm flour showed the presence of greater crystallinity and higher enthalpy change (∆Hgel) than vitreous endosperm flour for three cultivars. Retrogradation enthalpy (∆Hret) and retrogradation percentage (R) of vitreous and floury endosperm flours ranged from 6.23 to 7.92 J/g and 52.72% to 73.62%, and from 5.46 to 6.45 J/g and 45.70% to 56.58%, respectively. In conclusion, vitreous and floury endosperm flours had significantly different physicochemical properties. Results of this study provide a foundation for better and valid utilization of different endosperm section during grain processing.
    Schlagwörter flour ; floury endosperm ; maize ; physicochemical properties ; vitreous endosperm
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle Fachrepositorium Lebenswissenschaften

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  4. Buch ; Online: Authorship and Text-making in Early China

    Zhang, Hanmo

    (Library of Sinology [LOS])

    2018  

    Serientitel Library of Sinology [LOS]
    Schlagwörter Classical texts ; Regional studies ; Yellow Emperor ; Confucius ; Liu An Sima Qian
    Sprache Englisch
    Umfang 1 electronic resource (363 pages)
    Verlag De Gruyter
    Erscheinungsort Berlin/Boston
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030722112
    ISBN 9781501505195 ; 150150519X
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  5. Artikel: A novel, sensitive and non‐destructive method for quantitative determination of lipid in live Eriocheir sinensis using low‐field 1H Nuclear magnetic resonance

    Zhang, Hongcai

    Food Science & Nutrition, 6(8):1999-2004

    2018  

    Abstract: In this study, lipid content of live Eriocheir sinensis has been quickly and accurately determined by low‐field 1H Nuclear magnetic resonance (LF ‐1H NMR ). The experimental parameters of LF ‐1H NMR have been optimized and the validity of the established ...

    Abstract In this study, lipid content of live Eriocheir sinensis has been quickly and accurately determined by low‐field 1H Nuclear magnetic resonance (LF ‐1H NMR ). The experimental parameters of LF ‐1H NMR have been optimized and the validity of the established standard method has been confirmed with traditional Soxhlet extraction method. Results show that the lipid signal intensity is strongly correlated with its content and exhibits a good linear correlation (Y = 0.0376 + 4.899X , R 2 = 0.9999), thus demonstrating favorable accuracy and sensitivity for the quantitative determination of lipid content. In conclusion, the lipid content of live E. Sinensis can be directly obtained based on an established method, indicating a great application potential in food and other fields.
    Schlagwörter lipid ; Eriocheir sinensis ; Soxhlet extraction ; non-destructive analysis ; nuclear magnetic resonance
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle Fachrepositorium Lebenswissenschaften

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  6. Artikel: Effects of Sporidiobolus pararoseus Y16 on Postharvest Blue Mold Decay and the Defense Response of Apples

    Zhang, Hongyin

    Journal of food quality, 2018:6731762

    2018  

    Abstract: The efficacy of Sporidiobolus pararoseus Y16 in controlling postharvest blue mold caused by Penicillium expansum on apples and the defense response involved were evaluated. The results suggested that the decay incidence of blue mold of apples treated by ... ...

    Abstract The efficacy of Sporidiobolus pararoseus Y16 in controlling postharvest blue mold caused by Penicillium expansum on apples and the defense response involved were evaluated. The results suggested that the decay incidence of blue mold of apples treated by S. pararoseus Y16 was significantly reduced compared with the control. In vitro testing indicated that germination of spores and germ tube length of P. expansum were markedly inhibited by S. pararoseus Y16. Meanwhile, polyphenol oxidase (PPO), peroxidase (POD), phenylalanine ammonia lyase (PAL), and catalase (CAT) activities and several pathogenesis-related (PR) gene expression levels (including PR3, PR4, PR5, and PR9) were determined. In apples, the activities of PPO, POD, CAT, and PAL were significantly induced by S. pararoseus Y16 treatment compared with the control fruits. The relative expression levels of PR3 and PR4 were significantly induced at 4 and 6 d, while PR5 was significantly induced at 4 and 6 d and PR9 was significantly induced at 4 d. Therefore, the reduction in apple fruit decay by S. pararoseus Y16 treatment could be related to the increased activities of related enzymes and proteins involved in the defense against pathogens, which suggest that S. pararoseus Y16 is a potential antagonistic yeast.
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle Fachrepositorium Lebenswissenschaften

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  7. Artikel ; Online: Propagation of integral and fractional perfect vortex beams in a gradient-index medium.

    Zhang, Hanghang

    Applied optics

    2024  Band 63, Heft 2, Seite(n) 492–498

    Abstract: The analytical expressions for the complex amplitude of integral and fractional perfect vortex (PV) beams propagating in a gradient-index (GRIN) medium are derived. The intensity and phase distributions, propagation trajectories, Poynting vectors, and ... ...

    Abstract The analytical expressions for the complex amplitude of integral and fractional perfect vortex (PV) beams propagating in a gradient-index (GRIN) medium are derived. The intensity and phase distributions, propagation trajectories, Poynting vectors, and the effects of topological charge and refractive index at the medium axis on the intensity of both beams in the medium are numerically investigated. It is shown that both beams propagate periodically in the GRIN medium with alternating spot focusing and reconstruction. Unlike the integral PV beam, the fractional PV beam has a dark line in intensity profiles and a line edge dislocation in phase distributions along the positive
    Sprache Englisch
    Erscheinungsdatum 2024-01-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.507662
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Bicuspid aortic valve repair-current techniques, outcomes, challenges, and future perspectives.

    Zhang, Haiyu

    Frontiers in cardiovascular medicine

    2024  Band 10, Seite(n) 1295146

    Abstract: Bicuspid aortic valve (BAV) is a common congenital heart condition that can lead to some valve-related complications, such as aortic stenosis and/or regurgitation, and is often associated with aortic root dilation. With the development and refinement of ... ...

    Abstract Bicuspid aortic valve (BAV) is a common congenital heart condition that can lead to some valve-related complications, such as aortic stenosis and/or regurgitation, and is often associated with aortic root dilation. With the development and refinement of BAV repair techniques over the past three decades, surgical repair of BAV has emerged as an effective treatment option, offering symptomatic relief and improved outcomes. This review aims to summarize the current techniques, outcomes, and challenges of BAV repair, and to provide potential future perspectives in the field.
    Sprache Englisch
    Erscheinungsdatum 2024-01-03
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1295146
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Psychological wellbeing in Chinese university students: insights into the influences of academic self-concept, teacher support, and student engagement.

    Zhang, Hua

    Frontiers in psychology

    2024  Band 14, Seite(n) 1336682

    Abstract: Objective: This study investigates the complex interplay between academic self-concept, teacher support, student engagement, and psychological wellbeing among Chinese university students. We aimed to elucidate the mediating role of student engagement in ...

    Abstract Objective: This study investigates the complex interplay between academic self-concept, teacher support, student engagement, and psychological wellbeing among Chinese university students. We aimed to elucidate the mediating role of student engagement in these relationships.
    Methods: A sample of 597 Chinese undergraduate students from diverse universities participated in the study. We employed structured questionnaires to assess academic self-concept, teacher support, student engagement, and psychological wellbeing. Confirmatory factor analyses and structural equation modeling were used to test our hypothesized model.
    Results: Structural equation modeling indicated that the partial mediation model, which considered both direct and indirect effects, outperformed full mediation and direct effect models. Student engagement significantly mediated the relationships between academic self-concept, teacher support, and psychological wellbeing. Importantly, teacher support demonstrated a direct impact on psychological wellbeing, even when accounting for the mediating role of student engagement.
    Conclusion: This study underscores the pivotal role of student engagement as a mediator in the relationship between academic self-concept, teacher support, and psychological wellbeing among Chinese university students. While student engagement plays a substantial mediating role, our findings also recognize the persistent direct influence of teacher support on psychological wellbeing. These insights have implications for educators and policymakers aiming to enhance the wellbeing of university students by fostering positive academic self-concept and teacher support while recognizing the importance of student engagement.
    Sprache Englisch
    Erscheinungsdatum 2024-01-16
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1336682
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Buch ; Online: Plateau Lake Water Quality and Eutrophication: Status and Challenges

    Zhang, Hucai / Chen, Jingan / Haffner, G.D

    2023  

    Schlagwörter Earth sciences, geography, environment, planning ; external loading ; internal loading ; water quality ; tributary ; Lake Xingyun ; Lake Chenghai ; Yunnan ; water quality parameters ; seasonality ; spatial heterogeneity ; La-modified material ; macrophyte ; sediments ; phosphorus ; eutrophication ; particulate organic matter (POM) ; carbon and nitrogen stable isotopes ; source tracing ; ecosystem degradation ; Caohai Lake ; middle reach of the Jinsha River ; cascade hydropower development ; regression discontinuity analysis ; Lake Lugu ; thermal stratification ; seasonal changes ; Lake Qilu ; seasonal variation ; water temperature ; dissolved oxygen ; chlorophyll-a ; pH ; turbidity ; plateau lake ; nutrient limitation transformation ; nutrient threshold ; alkaline lake ; phytoplankton blooms ; Lake Yangzong ; temporal and spatial variations ; cyanophyte relative quantity index ; nutrient reduction ; n/a ; Lake Yilong ; spatial-temporal variations ; anthropogenic activities ; Lake Erhai ; temperature ; Chl-a ; nutrient elements ; heavy metal elements ; spatiotemporal characteristics ; entropy method-fuzzy evaluation method ; principal component analysis ; spatial variation ; temporal variation
    Sprache Englisch
    Umfang 1 electronic resource (248 pages)
    Verlag MDPI - Multidisciplinary Digital Publishing Institute
    Erscheinungsort Basel
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030374346
    ISBN 9783036564647 ; 3036564640
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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