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  1. Buch: Clinical chemistry

    Marshall, William J. / Lapsley, Marta / Day, Andrew P. / Shipman, Kate

    2021  

    Verfasserangabe William J. Marshall, Marta Lapsley, Andrew Day, Kate Shipman
    Schlagwörter Clinical chemistry
    Thema/Rubrik (Code) 616.0756
    Sprache Englisch
    Umfang ix, 419 Seiten, Illustrationen, 24 cm
    Ausgabenhinweis Ninth edition
    Verlag Elsevier
    Erscheinungsort St. Louis, Missouri
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    Anmerkung Zugang zur Online-Ausgabe über Code
    HBZ-ID HT020577569
    ISBN 978-0-702-0-7936-8 ; 978-0-702-0-7936- ; 978-0-702-07930-6 ; 0-702-0-7936-7 ; 0-702-07930-8
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Artikel: Editorial: Insights in pediatric gastroenterology, hepatology and nutrition: 2022.

    Day, Andrew S

    Frontiers in pediatrics

    2023  Band 11, Seite(n) 1210986

    Sprache Englisch
    Erscheinungsdatum 2023-05-12
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2023.1210986
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Selection of ethanol tolerant strains of Candida albicans by repeated ethanol exposure results in strains with reduced susceptibility to fluconazole.

    Day, Andrew W / Kumamoto, Carol A

    PloS one

    2024  Band 19, Heft 2, Seite(n) e0298724

    Abstract: Candida albicans is a commensal yeast that has important impacts on host metabolism and immune function, and can establish life-threatening infections in immunocompromised individuals. Previously, C. albicans colonization has been shown to contribute to ... ...

    Abstract Candida albicans is a commensal yeast that has important impacts on host metabolism and immune function, and can establish life-threatening infections in immunocompromised individuals. Previously, C. albicans colonization has been shown to contribute to the progression and severity of alcoholic liver disease. However, relatively little is known about how C. albicans responds to changing environmental conditions in the GI tract of individuals with alcohol use disorder, namely repeated exposure to ethanol. In this study, we repeatedly exposed C. albicans to high concentrations (10% vol/vol) of ethanol-a concentration that can be observed in the upper GI tract of humans following consumption of alcohol. Following this repeated exposure protocol, ethanol small colony (Esc) variants of C. albicans isolated from these populations exhibited increased ethanol tolerance, altered transcriptional responses to ethanol, and cross-resistance/tolerance to the frontline antifungal fluconazole. These Esc strains exhibited chromosomal copy number variations and carried polymorphisms in genes previously associated with the acquisition of fluconazole resistance during human infection. This study identifies a selective pressure that can result in evolution of fluconazole tolerance and resistance without previous exposure to the drug.
    Mesh-Begriff(e) Humans ; Fluconazole/pharmacology ; Candida albicans ; Ethanol/pharmacology ; DNA Copy Number Variations ; Antifungal Agents/pharmacology ; Antifungal Agents/therapeutic use ; Microbial Sensitivity Tests ; Drug Resistance, Fungal/genetics
    Chemische Substanzen Fluconazole (8VZV102JFY) ; Ethanol (3K9958V90M) ; Antifungal Agents
    Sprache Englisch
    Erscheinungsdatum 2024-02-20
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298724
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: At a crossroads? Offender rehabilitation in Australian prisons.

    Day, Andrew

    Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law

    2020  Band 27, Heft 6, Seite(n) 939–949

    Abstract: This article presents a commentary on the current status of offender rehabilitation in Australian prisons. Prompted by recent debates concerning the value of rehabilitation programs in reducing rates of re-imprisonment, it considers the current evidence ... ...

    Abstract This article presents a commentary on the current status of offender rehabilitation in Australian prisons. Prompted by recent debates concerning the value of rehabilitation programs in reducing rates of re-imprisonment, it considers the current evidence to support the effectiveness of Australian correctional programs highlighting the importance of the prison social climate, the intensity and quality of treatment and the need for psychological treatment to be integrated within broader models of rehabilitation and reintegration.
    Sprache Englisch
    Erscheinungsdatum 2020-04-17
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1331268-6
    ISSN 1934-1687 ; 1321-8719
    ISSN (online) 1934-1687
    ISSN 1321-8719
    DOI 10.1080/13218719.2020.1751335
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Time to stop and smell the roses: On 'rushing headlong' into service delivery without really knowing what it is we are doing.

    Day, Andrew

    Criminal behaviour and mental health : CBMH

    2020  Band 31, Heft 1, Seite(n) 5–8

    Sprache Englisch
    Erscheinungsdatum 2020-10-08
    Erscheinungsland England
    Dokumenttyp Editorial
    ZDB-ID 2042697-5
    ISSN 1471-2857 ; 0957-9664
    ISSN (online) 1471-2857
    ISSN 0957-9664
    DOI 10.1002/cbm.2171
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Advances in Nutrition in Pediatric Gastroenterology.

    Krishnan, Usha / Day, Andrew S

    Nutrients

    2023  Band 15, Heft 9

    Abstract: Chronic conditions affecting the gastrointestinal (GI) tract commonly impact nutrition adversely [ ... ]. ...

    Abstract Chronic conditions affecting the gastrointestinal (GI) tract commonly impact nutrition adversely [...].
    Mesh-Begriff(e) Child ; Humans ; Gastroenterology ; Gastrointestinal Tract ; Nutritional Status
    Sprache Englisch
    Erscheinungsdatum 2023-05-04
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15092181
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Selection of Ethanol Tolerant Strains of

    Day, Andrew W / Kumamoto, Carol A

    bioRxiv : the preprint server for biology

    2023  

    Abstract: ... Candida ... ...

    Abstract Candida albicans
    Sprache Englisch
    Erscheinungsdatum 2023-11-10
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2023.09.13.557677
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Interplay between host and Candida albicans during commensal gut colonization.

    Day, Andrew W / Kumamoto, Carol A

    PLoS pathogens

    2023  Band 19, Heft 9, Seite(n) e1011607

    Mesh-Begriff(e) Candida albicans ; Symbiosis ; Host Microbial Interactions
    Sprache Englisch
    Erscheinungsdatum 2023-09-14
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2205412-1
    ISSN 1553-7374 ; 1553-7374
    ISSN (online) 1553-7374
    ISSN 1553-7374
    DOI 10.1371/journal.ppat.1011607
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Looking for coeliac disease hiding in the family.

    Robson, Nicola / Day, Andrew S

    The Medical journal of Australia

    2023  Band 219, Heft 8, Seite(n) 355

    Sprache Englisch
    Erscheinungsdatum 2023-09-25
    Erscheinungsland Australia
    Dokumenttyp Editorial
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    DOI 10.5694/mja2.52116
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Exploring the Diagnostic Spectrum of Children with Raised Faecal Calprotectin Levels.

    Vernon-Roberts, Angharad / Humphrey, Olivia / Day, Andrew S

    Children (Basel, Switzerland)

    2024  Band 11, Heft 4

    Abstract: Faecal calprotectin (FC) is a marker of gut inflammation. The cause and relevance of raised FC in children outside the context of established inflammatory bowel disease (IBD) have had minimal attention. This study aimed to address this by carrying out a ... ...

    Abstract Faecal calprotectin (FC) is a marker of gut inflammation. The cause and relevance of raised FC in children outside the context of established inflammatory bowel disease (IBD) have had minimal attention. This study aimed to address this by carrying out a retrospective study on children with abnormal FC tests aged 4-17 years without established IBD in the South Island, New Zealand. Abnormal FC results were stratified: 51-249 μg/g, 250-499 μg/g, and 500+ μg/g, and participants were categorised into diagnostic groups. Data were collected on symptoms and diagnostic tests. Three-hundred and ten children had abnormal index FC results, with a mean age of 12.9 years, and a 55% proportion of females. The median FC was 125 μg/g; 71% had levels 51-249 μg/g and 21% had levels 500+ μg/g. Of those with FC 500+ μg/g, 89% either had infectious diarrhoea or were diagnosed with IBD at the time of, or subsequent to, the index FC. Alarm symptoms did not delineate between groups with FC 500+ μg/g. Abnormalities in platelet levels, abdominal ultrasound, and colonoscopy were more frequent for children diagnosed with IBD. Repeat FC test levels were significantly reduced except for those subsequently diagnosed with IBD. Abnormal FC levels for the majority were below the level indicative of mucosal inflammation. Repeat FC testing could play an important role in distinguishing between diagnoses.
    Sprache Englisch
    Erscheinungsdatum 2024-04-02
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children11040420
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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